EORTC QLQ Core 30 (C30) Questionnaire Score: Single Items
A Study of Atezolizumab Compared With Docetaxel in Participants With Locally Advanced or Metastatic Non-Small Cell Lung Cancer Who Have Failed Platinum-Containing Therapy · Source last updated 2019-12-20
Results reported by the registry submitting party. Population, time horizon, units and missing values must be read together.
Measure
MEAN
Unit
Units on a scale
Interval / dispersion
Standard Deviation
Time frame
Day 1 of each treatment Cycle up to EOT (up to approximately 2.25 years); 6 week following PD ( Pro Week 6 Pd) (up to approximately 2.25 years); survival follow-up-1 (up to approximately 2.25 years) (1 Cycle= 21 days)
What was measured
EORTC QLQ-C30 included global health status (GHS)/quality of life (QOL), functional scales (physical, role, cognitive, emotional, social), symptom scales (fatigue, pain, nausea/vomiting), and single items (dyspnea, appetite loss, insomnia, constipation, diarrhea, financial difficulties). Most questions from QLQ-C30 were a 4-point scale (1/Not at All to 4/Very Much), except Items 29-30, which comprise GHS scale and were a 7-point scale (1/Very Poor to 7/Excellent). For this instrument, GHS/QOL and functional scales were linearly transformed so each score ranged 0-100, where lower scores indicate poorer functioning (e.g., worsening) and higher scores indicate better functioning (e.g., improvement). Symptom scales/items were also linearly transformed so each score ranged 0-100, where higher scores indicate worse symptoms (e.g., more severe/worsened) and lower scores indicate less symptoms (e.g., less severe/improvement).
Analysis population: The PP-ITT analysis set. Here, 'n' signifies those participants evaluated for this measure at specific time point for each group respectively. All 850 participants contributed to the endpoint but not all completed evaluation of every timepoint. Convention 'CxDx' refers to cycle number and day number.
Groups in this outcome
Docetaxel
Docetaxel 75 milligrams per square meter (mg/m\^2) was administered intravenously (IV) on Day 1 of each 21-day cycle until disease progression, death, unacceptable toxicity, withdrawal of consent, or study termination by sponsor, whichever occurred first.
Atezolizumab
Atezolizumab 1200 mg was administered IV on Day 1 of each 21-day cycle until disease progression or loss of clinical benefit, death, unacceptable toxicity, withdrawal of consent, or study termination by sponsor, whichever occurred first.
Group identifiers and denominators belong to this outcome only. They may differ in another outcome or in safety reporting.
Analysis denominator · Participants
Group
Source count
Docetaxel
425
Atezolizumab
425
Reported measurements
Appetite Loss: Baseline (n= 390, 413)
Values in Units on a scale · Interval/dispersion: Standard Deviation
Group
Value
Spread
Lower
Upper
Comment
Docetaxel
26.58
31.57
Not reported
Not reported
Not reported
Atezolizumab
22.92
29.41
Not reported
Not reported
Not reported
Appetite Loss: Cycle (C) 2 Day (D) 1(n= 342, 368)
Values in Units on a scale · Interval/dispersion: Standard Deviation
Group
Value
Spread
Lower
Upper
Comment
Docetaxel
27.49
30.39
Not reported
Not reported
Not reported
Atezolizumab
26.99
31.16
Not reported
Not reported
Not reported
Appetite Loss: C3D1(n= 256, 304)
Values in Units on a scale · Interval/dispersion: Standard Deviation
Group
Value
Spread
Lower
Upper
Comment
Docetaxel
21.35
28.84
Not reported
Not reported
Not reported
Atezolizumab
21.16
28.94
Not reported
Not reported
Not reported
Appetite Loss: C4D1(n= 224, 279)
Values in Units on a scale · Interval/dispersion: Standard Deviation
Group
Value
Spread
Lower
Upper
Comment
Docetaxel
18.75
25.36
Not reported
Not reported
Not reported
Atezolizumab
18.40
26.60
Not reported
Not reported
Not reported
Appetite Loss: C5D1(n= 166, 238)
Values in Units on a scale · Interval/dispersion: Standard Deviation
Group
Value
Spread
Lower
Upper
Comment
Docetaxel
18.88
23.89
Not reported
Not reported
Not reported
Atezolizumab
16.67
27.52
Not reported
Not reported
Not reported
Appetite Loss: C6D1(n= 151, 224)
Values in Units on a scale · Interval/dispersion: Standard Deviation
Group
Value
Spread
Lower
Upper
Comment
Docetaxel
18.98
25.68
Not reported
Not reported
Not reported
Atezolizumab
14.88
25.39
Not reported
Not reported
Not reported
Appetite Loss: C7D1(n= 88, 190)
Values in Units on a scale · Interval/dispersion: Standard Deviation
Group
Value
Spread
Lower
Upper
Comment
Docetaxel
15.91
24.75
Not reported
Not reported
Not reported
Atezolizumab
12.46
23.06
Not reported
Not reported
Not reported
Appetite Loss: C8D1(n= 72, 170)
Values in Units on a scale · Interval/dispersion: Standard Deviation
Group
Value
Spread
Lower
Upper
Comment
Docetaxel
13.89
22.20
Not reported
Not reported
Not reported
Atezolizumab
12.94
23.27
Not reported
Not reported
Not reported
Appetite Loss: C9D1(n= 50, 153)
Values in Units on a scale · Interval/dispersion: Standard Deviation
Group
Value
Spread
Lower
Upper
Comment
Docetaxel
8.00
18.52
Not reported
Not reported
Not reported
Atezolizumab
11.33
22.35
Not reported
Not reported
Not reported
Appetite Loss: C10D1(n= 47, 146)
Values in Units on a scale · Interval/dispersion: Standard Deviation
Group
Value
Spread
Lower
Upper
Comment
Docetaxel
7.80
15.87
Not reported
Not reported
Not reported
Atezolizumab
12.33
21.45
Not reported
Not reported
Not reported
Appetite Loss: C11D1(n= 37, 134)
Values in Units on a scale · Interval/dispersion: Standard Deviation
Group
Value
Spread
Lower
Upper
Comment
Docetaxel
11.71
23.85
Not reported
Not reported
Not reported
Atezolizumab
11.44
22.43
Not reported
Not reported
Not reported
Appetite Loss: C12D1(n= 30, 132)
Values in Units on a scale · Interval/dispersion: Standard Deviation
Group
Value
Spread
Lower
Upper
Comment
Docetaxel
11.11
20.22
Not reported
Not reported
Not reported
Atezolizumab
8.84
18.81
Not reported
Not reported
Not reported
Appetite Loss: C13D1(n= 19, 123)
Values in Units on a scale · Interval/dispersion: Standard Deviation
Group
Value
Spread
Lower
Upper
Comment
Docetaxel
10.53
15.92
Not reported
Not reported
Not reported
Atezolizumab
8.40
15.74
Not reported
Not reported
Not reported
Appetite Loss: C14D1(n= 18, 120)
Values in Units on a scale · Interval/dispersion: Standard Deviation
Group
Value
Spread
Lower
Upper
Comment
Docetaxel
7.41
14.26
Not reported
Not reported
Not reported
Atezolizumab
10.00
17.61
Not reported
Not reported
Not reported
Appetite Loss: C15D1(n= 16, 113)
Values in Units on a scale · Interval/dispersion: Standard Deviation
Group
Value
Spread
Lower
Upper
Comment
Docetaxel
6.25
13.44
Not reported
Not reported
Not reported
Atezolizumab
12.39
22.80
Not reported
Not reported
Not reported
Appetite Loss: C16D1(n= 13, 109)
Values in Units on a scale · Interval/dispersion: Standard Deviation
Group
Value
Spread
Lower
Upper
Comment
Docetaxel
7.69
14.62
Not reported
Not reported
Not reported
Atezolizumab
10.09
19.51
Not reported
Not reported
Not reported
Appetite Loss: C17D1(n= 11, 98)
Values in Units on a scale · Interval/dispersion: Standard Deviation
Group
Value
Spread
Lower
Upper
Comment
Docetaxel
6.06
13.48
Not reported
Not reported
Not reported
Atezolizumab
7.82
18.41
Not reported
Not reported
Not reported
Appetite Loss: C18D1(n= 10, 91)
Values in Units on a scale · Interval/dispersion: Standard Deviation
Group
Value
Spread
Lower
Upper
Comment
Docetaxel
6.67
14.05
Not reported
Not reported
Not reported
Atezolizumab
8.06
18.15
Not reported
Not reported
Not reported
Appetite Loss: C19D1(n= 9, 84)
Values in Units on a scale · Interval/dispersion: Standard Deviation
Group
Value
Spread
Lower
Upper
Comment
Docetaxel
7.41
14.70
Not reported
Not reported
Not reported
Atezolizumab
9.13
18.18
Not reported
Not reported
Not reported
Appetite Loss: C20D1(n= 9, 80)
Values in Units on a scale · Interval/dispersion: Standard Deviation
Group
Value
Spread
Lower
Upper
Comment
Docetaxel
11.11
23.57
Not reported
Not reported
Not reported
Atezolizumab
9.58
21.34
Not reported
Not reported
Not reported
Appetite Loss: C21D1(n= 9, 75)
Values in Units on a scale · Interval/dispersion: Standard Deviation
Group
Value
Spread
Lower
Upper
Comment
Docetaxel
3.70
11.11
Not reported
Not reported
Not reported
Atezolizumab
12.44
26.15
Not reported
Not reported
Not reported
Appetite Loss: C22D1(n= 8, 69)
Values in Units on a scale · Interval/dispersion: Standard Deviation
Group
Value
Spread
Lower
Upper
Comment
Docetaxel
8.33
15.43
Not reported
Not reported
Not reported
Atezolizumab
6.76
16.74
Not reported
Not reported
Not reported
Appetite Loss: C23D1(n= 8, 66)
Values in Units on a scale · Interval/dispersion: Standard Deviation
Group
Value
Spread
Lower
Upper
Comment
Docetaxel
8.33
15.43
Not reported
Not reported
Not reported
Atezolizumab
7.58
17.34
Not reported
Not reported
Not reported
Appetite Loss: C24D1(n= 5, 64)
Values in Units on a scale · Interval/dispersion: Standard Deviation
Group
Value
Spread
Lower
Upper
Comment
Docetaxel
13.33
18.26
Not reported
Not reported
Not reported
Atezolizumab
8.33
15.71
Not reported
Not reported
Not reported
Appetite Loss: C25D1(n= 3, 60)
Values in Units on a scale · Interval/dispersion: Standard Deviation
Group
Value
Spread
Lower
Upper
Comment
Docetaxel
0.00
0.00
Not reported
Not reported
Not reported
Atezolizumab
6.11
13.01
Not reported
Not reported
Not reported
Appetite Loss: C26D1(n= 3, 55)
Values in Units on a scale · Interval/dispersion: Standard Deviation
Group
Value
Spread
Lower
Upper
Comment
Docetaxel
22.22
19.24
Not reported
Not reported
Not reported
Atezolizumab
5.45
12.45
Not reported
Not reported
Not reported
Appetite Loss: C27D1(n= 3, 52)
Values in Units on a scale · Interval/dispersion: Standard Deviation
Group
Value
Spread
Lower
Upper
Comment
Docetaxel
0.00
0.00
Not reported
Not reported
Not reported
Atezolizumab
9.62
19.06
Not reported
Not reported
Not reported
Appetite Loss: C28D1(n= 1, 49)
Values in Units on a scale · Interval/dispersion: Standard Deviation
Group
Value
Spread
Lower
Upper
Comment
Docetaxel
0.00
NA
Not reported
Not reported
Data not reported because standard deviation (SD) was non-estimable since only 1 participant was evaluated for this category.
Atezolizumab
7.48
15.61
Not reported
Not reported
Not reported
Appetite Loss: C29D1(n= 2, 40)
Values in Units on a scale · Interval/dispersion: Standard Deviation
Group
Value
Spread
Lower
Upper
Comment
Docetaxel
33.33
47.14
Not reported
Not reported
Not reported
Atezolizumab
9.17
16.86
Not reported
Not reported
Not reported
Appetite Loss: C30D1(n= 1, 31)
Values in Units on a scale · Interval/dispersion: Standard Deviation
Group
Value
Spread
Lower
Upper
Comment
Docetaxel
0.00
NA
Not reported
Not reported
Data not reported because SD was non-estimable since only 1 participant was evaluated for this category.
Atezolizumab
1.08
5.99
Not reported
Not reported
Not reported
Appetite Loss: C31D1(n= 0, 24)
Values in Units on a scale · Interval/dispersion: Standard Deviation
Group
Value
Spread
Lower
Upper
Comment
Docetaxel
NA
NA
Not reported
Not reported
Data not reported because no participant was evaluated for this category
Atezolizumab
6.94
13.83
Not reported
Not reported
Not reported
Appetite Loss: C32D1(n= 0, 22)
Values in Units on a scale · Interval/dispersion: Standard Deviation
Group
Value
Spread
Lower
Upper
Comment
Docetaxel
NA
NA
Not reported
Not reported
Data not reported because no participant was evaluated for this category
Atezolizumab
7.58
22.84
Not reported
Not reported
Not reported
Appetite Loss: C33D1(n= 0,16)
Values in Units on a scale · Interval/dispersion: Standard Deviation
Group
Value
Spread
Lower
Upper
Comment
Docetaxel
NA
NA
Not reported
Not reported
Data not reported because no participant was evaluated for this category
Atezolizumab
8.33
25.82
Not reported
Not reported
Not reported
Appetite Loss: C34D1(n= 0, 14)
Values in Units on a scale · Interval/dispersion: Standard Deviation
Group
Value
Spread
Lower
Upper
Comment
Docetaxel
NA
NA
Not reported
Not reported
Data not reported because no participant was evaluated for this category
Atezolizumab
4.76
17.82
Not reported
Not reported
Not reported
Appetite Loss: C35D1(n= 0, 12)
Values in Units on a scale · Interval/dispersion: Standard Deviation
Group
Value
Spread
Lower
Upper
Comment
Docetaxel
NA
NA
Not reported
Not reported
Data not reported because no participant was evaluated for this category
Atezolizumab
8.33
20.72
Not reported
Not reported
Not reported
Appetite Loss: C36D1(n= 0, 8)
Values in Units on a scale · Interval/dispersion: Standard Deviation
Group
Value
Spread
Lower
Upper
Comment
Docetaxel
NA
NA
Not reported
Not reported
Data not reported because no participant was evaluated for this category
Atezolizumab
4.17
11.78
Not reported
Not reported
Not reported
Appetite Loss: C37D1(n= 0, 5)
Values in Units on a scale · Interval/dispersion: Standard Deviation
Group
Value
Spread
Lower
Upper
Comment
Docetaxel
NA
NA
Not reported
Not reported
Data not reported because no participant was evaluated for this category
Atezolizumab
6.67
14.91
Not reported
Not reported
Not reported
Appetite Loss: C38D1(n= 0, 2)
Values in Units on a scale · Interval/dispersion: Standard Deviation
Group
Value
Spread
Lower
Upper
Comment
Docetaxel
NA
NA
Not reported
Not reported
Data not reported because no participant was evaluated for this category
Atezolizumab
0.00
0.00
Not reported
Not reported
Not reported
Appetite Loss: End of treatment (EOT)(n= 265, 246)
Values in Units on a scale · Interval/dispersion: Standard Deviation
Group
Value
Spread
Lower
Upper
Comment
Docetaxel
29.81
31.85
Not reported
Not reported
Not reported
Atezolizumab
31.98
33.51
Not reported
Not reported
Not reported
Appetite Loss: Pro Week 6 Pd(n= 0,1)
Values in Units on a scale · Interval/dispersion: Standard Deviation
Group
Value
Spread
Lower
Upper
Comment
Docetaxel
NA
NA
Not reported
Not reported
Data not reported because no participant was evaluated for this category
Atezolizumab
33.33
NA
Not reported
Not reported
Data not reported because SD was non-estimable since only 1 participant was evaluated for this category.
Values in Units on a scale · Interval/dispersion: Standard Deviation
Group
Value
Spread
Lower
Upper
Comment
Docetaxel
50.00
70.71
Not reported
Not reported
Not reported
Atezolizumab
66.67
NA
Not reported
Not reported
Data not reported because SD was non-estimable since only 1 participant was evaluated for this category.
Constipation: Baseline (n= 388, 410)
Values in Units on a scale · Interval/dispersion: Standard Deviation
Group
Value
Spread
Lower
Upper
Comment
Docetaxel
19.93
27.39
Not reported
Not reported
Not reported
Atezolizumab
16.50
26.81
Not reported
Not reported
Not reported
Constipation: C2D1(n= 339, 363)
Values in Units on a scale · Interval/dispersion: Standard Deviation
Group
Value
Spread
Lower
Upper
Comment
Docetaxel
19.47
26.42
Not reported
Not reported
Not reported
Atezolizumab
18.09
26.92
Not reported
Not reported
Not reported
Constipation: C3D1(n= 255, 304)
Values in Units on a scale · Interval/dispersion: Standard Deviation
Group
Value
Spread
Lower
Upper
Comment
Docetaxel
19.74
26.91
Not reported
Not reported
Not reported
Atezolizumab
15.13
23.71
Not reported
Not reported
Not reported
Constipation: C4D1(n= 224, 277)
Values in Units on a scale · Interval/dispersion: Standard Deviation
Group
Value
Spread
Lower
Upper
Comment
Docetaxel
17.86
23.38
Not reported
Not reported
Not reported
Atezolizumab
14.56
23.58
Not reported
Not reported
Not reported
Constipation: C5D1(n= 166, 236)
Values in Units on a scale · Interval/dispersion: Standard Deviation
Group
Value
Spread
Lower
Upper
Comment
Docetaxel
13.05
21.33
Not reported
Not reported
Not reported
Atezolizumab
12.15
21.16
Not reported
Not reported
Not reported
Constipation: C6D1(n= 151, 225)
Values in Units on a scale · Interval/dispersion: Standard Deviation
Group
Value
Spread
Lower
Upper
Comment
Docetaxel
14.35
23.89
Not reported
Not reported
Not reported
Atezolizumab
12.89
22.42
Not reported
Not reported
Not reported
Constipation: C7D1(n= 87, 188)
Values in Units on a scale · Interval/dispersion: Standard Deviation
Group
Value
Spread
Lower
Upper
Comment
Docetaxel
13.41
20.62
Not reported
Not reported
Not reported
Atezolizumab
11.52
21.04
Not reported
Not reported
Not reported
Constipation: C8D1(n= 72, 171)
Values in Units on a scale · Interval/dispersion: Standard Deviation
Group
Value
Spread
Lower
Upper
Comment
Docetaxel
8.33
15.57
Not reported
Not reported
Not reported
Atezolizumab
12.28
21.36
Not reported
Not reported
Not reported
Constipation: C9D1(n= 50, 153)
Values in Units on a scale · Interval/dispersion: Standard Deviation
Group
Value
Spread
Lower
Upper
Comment
Docetaxel
9.33
19.10
Not reported
Not reported
Not reported
Atezolizumab
10.68
17.79
Not reported
Not reported
Not reported
Constipation: C10D1(n= 47, 146)
Values in Units on a scale · Interval/dispersion: Standard Deviation
Group
Value
Spread
Lower
Upper
Comment
Docetaxel
9.22
17.99
Not reported
Not reported
Not reported
Atezolizumab
9.82
17.58
Not reported
Not reported
Not reported
Constipation: C11D1(n= 37, 134)
Values in Units on a scale · Interval/dispersion: Standard Deviation
Group
Value
Spread
Lower
Upper
Comment
Docetaxel
5.41
12.46
Not reported
Not reported
Not reported
Atezolizumab
9.95
17.83
Not reported
Not reported
Not reported
Constipation: C12D1(n= 30, 132)
Values in Units on a scale · Interval/dispersion: Standard Deviation
Group
Value
Spread
Lower
Upper
Comment
Docetaxel
11.11
20.22
Not reported
Not reported
Not reported
Atezolizumab
10.86
18.65
Not reported
Not reported
Not reported
Constipation: C13D1(n= 19, 124)
Values in Units on a scale · Interval/dispersion: Standard Deviation
Group
Value
Spread
Lower
Upper
Comment
Docetaxel
5.26
12.49
Not reported
Not reported
Not reported
Atezolizumab
8.60
15.83
Not reported
Not reported
Not reported
Constipation: C14D1(n= 17, 121)
Values in Units on a scale · Interval/dispersion: Standard Deviation
Group
Value
Spread
Lower
Upper
Comment
Docetaxel
15.69
23.91
Not reported
Not reported
Not reported
Atezolizumab
9.09
16.67
Not reported
Not reported
Not reported
Constipation: C15D1(n= 15, 113)
Values in Units on a scale · Interval/dispersion: Standard Deviation
Group
Value
Spread
Lower
Upper
Comment
Docetaxel
2.22
8.61
Not reported
Not reported
Not reported
Atezolizumab
10.03
17.75
Not reported
Not reported
Not reported
Constipation: C16D1(n= 13, 109)
Values in Units on a scale · Interval/dispersion: Standard Deviation
Group
Value
Spread
Lower
Upper
Comment
Docetaxel
20.51
32.03
Not reported
Not reported
Not reported
Atezolizumab
9.79
18.87
Not reported
Not reported
Not reported
Constipation: C17D1(n= 11, 98)
Values in Units on a scale · Interval/dispersion: Standard Deviation
Group
Value
Spread
Lower
Upper
Comment
Docetaxel
12.12
22.47
Not reported
Not reported
Not reported
Atezolizumab
9.86
19.27
Not reported
Not reported
Not reported
Constipation: C18D1(n= 10, 92)
Values in Units on a scale · Interval/dispersion: Standard Deviation
Group
Value
Spread
Lower
Upper
Comment
Docetaxel
6.67
14.05
Not reported
Not reported
Not reported
Atezolizumab
9.06
17.89
Not reported
Not reported
Not reported
Constipation: C19D1(n= 9, 83)
Values in Units on a scale · Interval/dispersion: Standard Deviation
Group
Value
Spread
Lower
Upper
Comment
Docetaxel
7.41
14.70
Not reported
Not reported
Not reported
Atezolizumab
9.64
18.43
Not reported
Not reported
Not reported
Constipation: C20D1(n=9, 80)
Values in Units on a scale · Interval/dispersion: Standard Deviation
Group
Value
Spread
Lower
Upper
Comment
Docetaxel
14.81
33.79
Not reported
Not reported
Not reported
Atezolizumab
12.50
23.35
Not reported
Not reported
Not reported
Constipation: C21D1(n= 9, 75)
Values in Units on a scale · Interval/dispersion: Standard Deviation
Group
Value
Spread
Lower
Upper
Comment
Docetaxel
7.41
14.70
Not reported
Not reported
Not reported
Atezolizumab
14.22
25.22
Not reported
Not reported
Not reported
Constipation: C22D1(n= 8, 69)
Values in Units on a scale · Interval/dispersion: Standard Deviation
Group
Value
Spread
Lower
Upper
Comment
Docetaxel
12.50
24.80
Not reported
Not reported
Not reported
Atezolizumab
11.59
21.26
Not reported
Not reported
Not reported
Constipation: C23D1(n= 8, 66)
Values in Units on a scale · Interval/dispersion: Standard Deviation
Group
Value
Spread
Lower
Upper
Comment
Docetaxel
4.17
11.78
Not reported
Not reported
Not reported
Atezolizumab
10.10
20.23
Not reported
Not reported
Not reported
Constipation: C24D1(n=5, 65)
Values in Units on a scale · Interval/dispersion: Standard Deviation
Group
Value
Spread
Lower
Upper
Comment
Docetaxel
20.00
29.81
Not reported
Not reported
Not reported
Atezolizumab
9.74
17.40
Not reported
Not reported
Not reported
Constipation: C25D1(n= 3, 60)
Values in Units on a scale · Interval/dispersion: Standard Deviation
Group
Value
Spread
Lower
Upper
Comment
Docetaxel
0.00
0.00
Not reported
Not reported
Not reported
Atezolizumab
11.11
19.08
Not reported
Not reported
Not reported
Constipation: C26D1(n= 2, 55)
Values in Units on a scale · Interval/dispersion: Standard Deviation
Group
Value
Spread
Lower
Upper
Comment
Docetaxel
0.00
0.00
Not reported
Not reported
Not reported
Atezolizumab
12.12
20.65
Not reported
Not reported
Not reported
Constipation: C27D1(n= 3, 52)
Values in Units on a scale · Interval/dispersion: Standard Deviation
Group
Value
Spread
Lower
Upper
Comment
Docetaxel
0.00
0.00
Not reported
Not reported
Not reported
Atezolizumab
13.46
20.09
Not reported
Not reported
Not reported
Constipation: C28D1(n= 1, 48)
Values in Units on a scale · Interval/dispersion: Standard Deviation
Group
Value
Spread
Lower
Upper
Comment
Docetaxel
0.00
NA
Not reported
Not reported
Data not reported because SD was non-estimable since only 1 participant was evaluated for this category.
Atezolizumab
11.81
22.27
Not reported
Not reported
Not reported
Constipation: C29D1(n= 2, 40)
Values in Units on a scale · Interval/dispersion: Standard Deviation
Group
Value
Spread
Lower
Upper
Comment
Docetaxel
50.00
70.71
Not reported
Not reported
Not reported
Atezolizumab
15.83
23.86
Not reported
Not reported
Not reported
Constipation: C30D1(n= 1, 31)
Values in Units on a scale · Interval/dispersion: Standard Deviation
Group
Value
Spread
Lower
Upper
Comment
Docetaxel
0.00
NA
Not reported
Not reported
Data not reported because SD was non-estimable since only 1 participant was evaluated for this category.
Atezolizumab
8.60
19.18
Not reported
Not reported
Not reported
Constipation: C31D1(n= 0, 24)
Values in Units on a scale · Interval/dispersion: Standard Deviation
Group
Value
Spread
Lower
Upper
Comment
Docetaxel
NA
NA
Not reported
Not reported
Data not reported because no participant was evaluated for this category
Atezolizumab
9.72
20.80
Not reported
Not reported
Not reported
Constipation: C32D1(n= 0, 22)
Values in Units on a scale · Interval/dispersion: Standard Deviation
Group
Value
Spread
Lower
Upper
Comment
Docetaxel
NA
NA
Not reported
Not reported
Data not reported because no participant was evaluated for this category
Atezolizumab
6.06
13.16
Not reported
Not reported
Not reported
Constipation: C33D1(n= 0, 16)
Values in Units on a scale · Interval/dispersion: Standard Deviation
Group
Value
Spread
Lower
Upper
Comment
Docetaxel
NA
NA
Not reported
Not reported
Data not reported because no participant was evaluated for this category
Atezolizumab
4.17
11.39
Not reported
Not reported
Not reported
Constipation: C34D1(n= 0, 14)
Values in Units on a scale · Interval/dispersion: Standard Deviation
Group
Value
Spread
Lower
Upper
Comment
Docetaxel
NA
NA
Not reported
Not reported
Data not reported because no participant was evaluated for this category
Atezolizumab
7.14
14.19
Not reported
Not reported
Not reported
Constipation: C35D1(n= 0, 12)
Values in Units on a scale · Interval/dispersion: Standard Deviation
Group
Value
Spread
Lower
Upper
Comment
Docetaxel
NA
NA
Not reported
Not reported
Data not reported because no participant was evaluated for this category
Atezolizumab
5.56
12.97
Not reported
Not reported
Not reported
Constipation: C36D1(n= 0, 8)
Values in Units on a scale · Interval/dispersion: Standard Deviation
Group
Value
Spread
Lower
Upper
Comment
Docetaxel
NA
NA
Not reported
Not reported
Data not reported because no participant was evaluated for this category
Atezolizumab
4.17
11.78
Not reported
Not reported
Not reported
Constipation: C37D1(n= 0, 5)
Values in Units on a scale · Interval/dispersion: Standard Deviation
Group
Value
Spread
Lower
Upper
Comment
Docetaxel
NA
NA
Not reported
Not reported
Data not reported because no participant was evaluated for this category
Atezolizumab
0.00
0.00
Not reported
Not reported
Not reported
Constipation: C38D1(n= 0, 2)
Values in Units on a scale · Interval/dispersion: Standard Deviation
Group
Value
Spread
Lower
Upper
Comment
Docetaxel
NA
NA
Not reported
Not reported
Data not reported because no participant was evaluated for this category
Atezolizumab
0.00
0.00
Not reported
Not reported
Not reported
Constipation: EOT (n= 265, 246)
Values in Units on a scale · Interval/dispersion: Standard Deviation
Group
Value
Spread
Lower
Upper
Comment
Docetaxel
19.12
27.28
Not reported
Not reported
Not reported
Atezolizumab
19.78
28.36
Not reported
Not reported
Not reported
Constipation: Pro Week 6 Pd(n= 0,1)
Values in Units on a scale · Interval/dispersion: Standard Deviation
Group
Value
Spread
Lower
Upper
Comment
Docetaxel
NA
NA
Not reported
Not reported
Data not reported because no participant was evaluated for this category
Atezolizumab
66.67
NA
Not reported
Not reported
Data not reported because SD was non-estimable since only 1 participant was evaluated for this category.
Constipation: Survival FU-1 (n= 2,1)
Values in Units on a scale · Interval/dispersion: Standard Deviation
Group
Value
Spread
Lower
Upper
Comment
Docetaxel
33.33
47.14
Not reported
Not reported
Not reported
Atezolizumab
66.67
NA
Not reported
Not reported
Data not reported because SD was non-estimable since only 1 participant was evaluated for this category.
Diarrhea: Baseline (n= 388, 411)
Values in Units on a scale · Interval/dispersion: Standard Deviation
Group
Value
Spread
Lower
Upper
Comment
Docetaxel
5.84
13.77
Not reported
Not reported
Not reported
Atezolizumab
7.22
17.86
Not reported
Not reported
Not reported
Diarrhea: C2D1(n= 339, 361)
Values in Units on a scale · Interval/dispersion: Standard Deviation
Group
Value
Spread
Lower
Upper
Comment
Docetaxel
11.21
20.65
Not reported
Not reported
Not reported
Atezolizumab
7.29
17.72
Not reported
Not reported
Not reported
Diarrhea: C3D1(n= 255, 304)
Values in Units on a scale · Interval/dispersion: Standard Deviation
Group
Value
Spread
Lower
Upper
Comment
Docetaxel
10.07
18.68
Not reported
Not reported
Not reported
Atezolizumab
6.14
15.75
Not reported
Not reported
Not reported
Diarrhea: C4D1(n= 223, 280)
Values in Units on a scale · Interval/dispersion: Standard Deviation
Group
Value
Spread
Lower
Upper
Comment
Docetaxel
8.22
16.35
Not reported
Not reported
Not reported
Atezolizumab
6.67
17.71
Not reported
Not reported
Not reported
Diarrhea: C5D1(n= 166, 238)
Values in Units on a scale · Interval/dispersion: Standard Deviation
Group
Value
Spread
Lower
Upper
Comment
Docetaxel
8.43
17.48
Not reported
Not reported
Not reported
Atezolizumab
6.58
16.16
Not reported
Not reported
Not reported
Diarrhea: C6D1(n= 151, 222)
Values in Units on a scale · Interval/dispersion: Standard Deviation
Group
Value
Spread
Lower
Upper
Comment
Docetaxel
7.51
14.99
Not reported
Not reported
Not reported
Atezolizumab
6.31
14.88
Not reported
Not reported
Not reported
Diarrhea: C7D1(n= 87, 189)
Values in Units on a scale · Interval/dispersion: Standard Deviation
Group
Value
Spread
Lower
Upper
Comment
Docetaxel
10.34
17.10
Not reported
Not reported
Not reported
Atezolizumab
7.94
17.24
Not reported
Not reported
Not reported
Diarrhea: C8D1(n= 72, 171)
Values in Units on a scale · Interval/dispersion: Standard Deviation
Group
Value
Spread
Lower
Upper
Comment
Docetaxel
7.41
15.03
Not reported
Not reported
Not reported
Atezolizumab
8.77
17.56
Not reported
Not reported
Not reported
Diarrhea: C9D1(n= 50, 153)
Values in Units on a scale · Interval/dispersion: Standard Deviation
Group
Value
Spread
Lower
Upper
Comment
Docetaxel
11.33
17.31
Not reported
Not reported
Not reported
Atezolizumab
7.63
16.44
Not reported
Not reported
Not reported
Diarrhea: C10D1(n= 47, 146)
Values in Units on a scale · Interval/dispersion: Standard Deviation
Group
Value
Spread
Lower
Upper
Comment
Docetaxel
7.80
14.27
Not reported
Not reported
Not reported
Atezolizumab
5.48
15.67
Not reported
Not reported
Not reported
Diarrhea: C11D1(n= 36, 134)
Values in Units on a scale · Interval/dispersion: Standard Deviation
Group
Value
Spread
Lower
Upper
Comment
Docetaxel
8.33
14.64
Not reported
Not reported
Not reported
Atezolizumab
4.98
14.46
Not reported
Not reported
Not reported
Diarrhea: C12D1(n= 30, 132)
Values in Units on a scale · Interval/dispersion: Standard Deviation
Group
Value
Spread
Lower
Upper
Comment
Docetaxel
10.00
17.83
Not reported
Not reported
Not reported
Atezolizumab
6.31
16.54
Not reported
Not reported
Not reported
Diarrhea: C13D1(n= 18, 124)
Values in Units on a scale · Interval/dispersion: Standard Deviation
Group
Value
Spread
Lower
Upper
Comment
Docetaxel
11.11
16.17
Not reported
Not reported
Not reported
Atezolizumab
5.65
14.55
Not reported
Not reported
Not reported
Diarrhea: C14D1(n= 17, 121)
Values in Units on a scale · Interval/dispersion: Standard Deviation
Group
Value
Spread
Lower
Upper
Comment
Docetaxel
3.92
11.07
Not reported
Not reported
Not reported
Atezolizumab
9.92
19.07
Not reported
Not reported
Not reported
Diarrhea: C15D1(n= 15, 113)
Values in Units on a scale · Interval/dispersion: Standard Deviation
Group
Value
Spread
Lower
Upper
Comment
Docetaxel
8.89
15.26
Not reported
Not reported
Not reported
Atezolizumab
7.96
17.97
Not reported
Not reported
Not reported
Diarrhea: C16D1(n= 12, 108)
Values in Units on a scale · Interval/dispersion: Standard Deviation
Group
Value
Spread
Lower
Upper
Comment
Docetaxel
13.89
17.16
Not reported
Not reported
Not reported
Atezolizumab
6.48
14.02
Not reported
Not reported
Not reported
Diarrhea: C17D1(n= 11, 98)
Values in Units on a scale · Interval/dispersion: Standard Deviation
Group
Value
Spread
Lower
Upper
Comment
Docetaxel
9.09
15.57
Not reported
Not reported
Not reported
Atezolizumab
7.82
16.44
Not reported
Not reported
Not reported
Diarrhea: C18D1(n= 10, 92)
Values in Units on a scale · Interval/dispersion: Standard Deviation
Group
Value
Spread
Lower
Upper
Comment
Docetaxel
13.33
17.21
Not reported
Not reported
Not reported
Atezolizumab
8.70
17.73
Not reported
Not reported
Not reported
Diarrhea: C19D1(n= 9, 84)
Values in Units on a scale · Interval/dispersion: Standard Deviation
Group
Value
Spread
Lower
Upper
Comment
Docetaxel
14.81
17.57
Not reported
Not reported
Not reported
Atezolizumab
7.94
18.38
Not reported
Not reported
Not reported
Diarrhea: C20D1(n= 9, 80)
Values in Units on a scale · Interval/dispersion: Standard Deviation
Group
Value
Spread
Lower
Upper
Comment
Docetaxel
7.41
14.70
Not reported
Not reported
Not reported
Atezolizumab
6.67
14.43
Not reported
Not reported
Not reported
Diarrhea: C21D1(n= 9, 75)
Values in Units on a scale · Interval/dispersion: Standard Deviation
Group
Value
Spread
Lower
Upper
Comment
Docetaxel
18.52
17.57
Not reported
Not reported
Not reported
Atezolizumab
11.11
18.45
Not reported
Not reported
Not reported
Diarrhea: C22D1(n= 8, 68)
Values in Units on a scale · Interval/dispersion: Standard Deviation
Group
Value
Spread
Lower
Upper
Comment
Docetaxel
16.67
25.20
Not reported
Not reported
Not reported
Atezolizumab
7.84
16.41
Not reported
Not reported
Not reported
Diarrhea: C23D1(n= 8, 66)
Values in Units on a scale · Interval/dispersion: Standard Deviation
Group
Value
Spread
Lower
Upper
Comment
Docetaxel
8.33
15.43
Not reported
Not reported
Not reported
Atezolizumab
6.06
16.44
Not reported
Not reported
Not reported
Diarrhea: C24D1(n= 5, 64)
Values in Units on a scale · Interval/dispersion: Standard Deviation
Group
Value
Spread
Lower
Upper
Comment
Docetaxel
6.67
14.91
Not reported
Not reported
Not reported
Atezolizumab
6.25
16.67
Not reported
Not reported
Not reported
Diarrhea: C25D1(n= 3, 60)
Values in Units on a scale · Interval/dispersion: Standard Deviation
Group
Value
Spread
Lower
Upper
Comment
Docetaxel
0.00
0.00
Not reported
Not reported
Not reported
Atezolizumab
6.11
14.38
Not reported
Not reported
Not reported
Diarrhea: C26D1(n= 3, 55)
Values in Units on a scale · Interval/dispersion: Standard Deviation
Group
Value
Spread
Lower
Upper
Comment
Docetaxel
11.11
19.24
Not reported
Not reported
Not reported
Atezolizumab
10.30
21.15
Not reported
Not reported
Not reported
Diarrhea: C27D1(n= 3, 52)
Values in Units on a scale · Interval/dispersion: Standard Deviation
Group
Value
Spread
Lower
Upper
Comment
Docetaxel
11.11
19.24
Not reported
Not reported
Not reported
Atezolizumab
5.77
15.79
Not reported
Not reported
Not reported
Diarrhea: C28D1(n= 1, 48)
Values in Units on a scale · Interval/dispersion: Standard Deviation
Group
Value
Spread
Lower
Upper
Comment
Docetaxel
0.00
NA
Not reported
Not reported
Data not reported because SD was non-estimable since only 1 participant was evaluated for this category.
Atezolizumab
4.86
13.73
Not reported
Not reported
Not reported
Diarrhea: C29D1(n= 2, 40)
Values in Units on a scale · Interval/dispersion: Standard Deviation
Group
Value
Spread
Lower
Upper
Comment
Docetaxel
50.00
70.71
Not reported
Not reported
Not reported
Atezolizumab
9.17
18.47
Not reported
Not reported
Not reported
Diarrhea: C30D1(n= 1, 31)
Values in Units on a scale · Interval/dispersion: Standard Deviation
Group
Value
Spread
Lower
Upper
Comment
Docetaxel
0.00
NA
Not reported
Not reported
Data not reported because SD was non-estimable since only 1 participant was evaluated for this category.
Atezolizumab
7.53
16.58
Not reported
Not reported
Not reported
Diarrhea: C31D1(n= 0, 24)
Values in Units on a scale · Interval/dispersion: Standard Deviation
Group
Value
Spread
Lower
Upper
Comment
Docetaxel
NA
NA
Not reported
Not reported
Data not reported because no participant was evaluated for this category
Atezolizumab
6.94
16.97
Not reported
Not reported
Not reported
Diarrhea: C32D1(n= 0, 22)
Values in Units on a scale · Interval/dispersion: Standard Deviation
Group
Value
Spread
Lower
Upper
Comment
Docetaxel
NA
NA
Not reported
Not reported
Data not reported because no participant was evaluated for this category
Atezolizumab
12.12
16.41
Not reported
Not reported
Not reported
Diarrhea: C33D1(n= 0, 16)
Values in Units on a scale · Interval/dispersion: Standard Deviation
Group
Value
Spread
Lower
Upper
Comment
Docetaxel
NA
NA
Not reported
Not reported
Data not reported because no participant was evaluated for this category
Atezolizumab
8.33
14.91
Not reported
Not reported
Not reported
Diarrhea: C34D1(n= 0, 14)
Values in Units on a scale · Interval/dispersion: Standard Deviation
Group
Value
Spread
Lower
Upper
Comment
Docetaxel
NA
NA
Not reported
Not reported
Data not reported because no participant was evaluated for this category
Atezolizumab
4.76
12.10
Not reported
Not reported
Not reported
Diarrhea: C35D1(n= 0, 12)
Values in Units on a scale · Interval/dispersion: Standard Deviation
Group
Value
Spread
Lower
Upper
Comment
Docetaxel
NA
NA
Not reported
Not reported
Data not reported because no participant was evaluated for this category
Atezolizumab
5.56
12.97
Not reported
Not reported
Not reported
Diarrhea: C36D1(n= 0, 8)
Values in Units on a scale · Interval/dispersion: Standard Deviation
Group
Value
Spread
Lower
Upper
Comment
Docetaxel
NA
NA
Not reported
Not reported
Data not reported because no participant was evaluated for this category
Atezolizumab
4.17
11.78
Not reported
Not reported
Not reported
Diarrhea: C37D1(n= 0, 5)
Values in Units on a scale · Interval/dispersion: Standard Deviation
Group
Value
Spread
Lower
Upper
Comment
Docetaxel
NA
NA
Not reported
Not reported
Data not reported because no participant was evaluated for this category
Atezolizumab
6.67
14.91
Not reported
Not reported
Not reported
Diarrhea: C38D1(n= 0, 2)
Values in Units on a scale · Interval/dispersion: Standard Deviation
Group
Value
Spread
Lower
Upper
Comment
Docetaxel
NA
NA
Not reported
Not reported
Data not reported because no participant was evaluated for this category
Atezolizumab
0.00
0.00
Not reported
Not reported
Not reported
Diarrhea: EOT(n= 265, 246)
Values in Units on a scale · Interval/dispersion: Standard Deviation
Group
Value
Spread
Lower
Upper
Comment
Docetaxel
10.57
19.18
Not reported
Not reported
Not reported
Atezolizumab
9.35
20.39
Not reported
Not reported
Not reported
Diarrhea: Pro Week 6 Pd(n= 0, 1)
Values in Units on a scale · Interval/dispersion: Standard Deviation
Group
Value
Spread
Lower
Upper
Comment
Docetaxel
NA
NA
Not reported
Not reported
Data not reported because no participant was evaluated for this category
Atezolizumab
0.00
NA
Not reported
Not reported
Data not reported because SD was non-estimable since only 1 participant was evaluated for this category.
Diarrhea: Survival FU-1 (n= 2, 1)
Values in Units on a scale · Interval/dispersion: Standard Deviation
Group
Value
Spread
Lower
Upper
Comment
Docetaxel
33.33
47.14
Not reported
Not reported
Not reported
Atezolizumab
33.33
NA
Not reported
Not reported
Data not reported because SD was non-estimable since only 1 participant was evaluated for this category.
Financial Difficulties: Baseline (n=387, 411)
Values in Units on a scale · Interval/dispersion: Standard Deviation
Group
Value
Spread
Lower
Upper
Comment
Docetaxel
20.76
27.61
Not reported
Not reported
Not reported
Atezolizumab
18.09
28.32
Not reported
Not reported
Not reported
Financial Difficulties: C2D1 (n=336, 362)
Values in Units on a scale · Interval/dispersion: Standard Deviation
Group
Value
Spread
Lower
Upper
Comment
Docetaxel
18.45
26.20
Not reported
Not reported
Not reported
Atezolizumab
15.93
26.28
Not reported
Not reported
Not reported
Financial Difficulties: C3D1 (n=253, 305)
Values in Units on a scale · Interval/dispersion: Standard Deviation
Group
Value
Spread
Lower
Upper
Comment
Docetaxel
16.86
24.24
Not reported
Not reported
Not reported
Atezolizumab
15.63
25.79
Not reported
Not reported
Not reported
Financial Difficulties: C4D1 (n=219, 280)
Values in Units on a scale · Interval/dispersion: Standard Deviation
Group
Value
Spread
Lower
Upper
Comment
Docetaxel
16.74
23.97
Not reported
Not reported
Not reported
Atezolizumab
15.12
24.72
Not reported
Not reported
Not reported
Financial Difficulties: C5D1 (n=165, 238)
Values in Units on a scale · Interval/dispersion: Standard Deviation
Group
Value
Spread
Lower
Upper
Comment
Docetaxel
16.57
24.03
Not reported
Not reported
Not reported
Atezolizumab
15.13
25.71
Not reported
Not reported
Not reported
Financial Difficulties: C6D1 (n=149, 224)
Values in Units on a scale · Interval/dispersion: Standard Deviation
Group
Value
Spread
Lower
Upper
Comment
Docetaxel
15.66
24.06
Not reported
Not reported
Not reported
Atezolizumab
16.67
26.41
Not reported
Not reported
Not reported
Financial Difficulties: C7D1 (n=86, 189)
Values in Units on a scale · Interval/dispersion: Standard Deviation
Group
Value
Spread
Lower
Upper
Comment
Docetaxel
16.28
24.92
Not reported
Not reported
Not reported
Atezolizumab
17.46
27.41
Not reported
Not reported
Not reported
Financial Difficulties: C8D1 (n=71, 170)
Values in Units on a scale · Interval/dispersion: Standard Deviation
Group
Value
Spread
Lower
Upper
Comment
Docetaxel
13.15
21.44
Not reported
Not reported
Not reported
Atezolizumab
18.82
27.59
Not reported
Not reported
Not reported
Financial Difficulties: C9D1 (n=49, 152)
Values in Units on a scale · Interval/dispersion: Standard Deviation
Group
Value
Spread
Lower
Upper
Comment
Docetaxel
16.33
28.16
Not reported
Not reported
Not reported
Atezolizumab
17.54
27.38
Not reported
Not reported
Not reported
Financial Difficulties: C10D1 (n=46, 146)
Values in Units on a scale · Interval/dispersion: Standard Deviation
Group
Value
Spread
Lower
Upper
Comment
Docetaxel
14.49
23.99
Not reported
Not reported
Not reported
Atezolizumab
17.81
29.08
Not reported
Not reported
Not reported
Financial Difficulties: C11D1 (n=36, 134)
Values in Units on a scale · Interval/dispersion: Standard Deviation
Group
Value
Spread
Lower
Upper
Comment
Docetaxel
9.26
21.98
Not reported
Not reported
Not reported
Atezolizumab
19.65
30.10
Not reported
Not reported
Not reported
Financial Difficulties: C12D1 (n=30, 132)
Values in Units on a scale · Interval/dispersion: Standard Deviation
Group
Value
Spread
Lower
Upper
Comment
Docetaxel
12.22
23.95
Not reported
Not reported
Not reported
Atezolizumab
18.43
28.92
Not reported
Not reported
Not reported
Financial Difficulties: C13D1 (n=18, 122)
Values in Units on a scale · Interval/dispersion: Standard Deviation
Group
Value
Spread
Lower
Upper
Comment
Docetaxel
12.96
25.92
Not reported
Not reported
Not reported
Atezolizumab
18.31
29.10
Not reported
Not reported
Not reported
Financial Difficulties: C14D1 (n=17, 121)
Values in Units on a scale · Interval/dispersion: Standard Deviation
Group
Value
Spread
Lower
Upper
Comment
Docetaxel
15.69
26.66
Not reported
Not reported
Not reported
Atezolizumab
18.46
29.17
Not reported
Not reported
Not reported
Financial Difficulties: C15D1 (n=15, 113)
Values in Units on a scale · Interval/dispersion: Standard Deviation
Group
Value
Spread
Lower
Upper
Comment
Docetaxel
6.67
18.69
Not reported
Not reported
Not reported
Atezolizumab
18.29
28.86
Not reported
Not reported
Not reported
Financial Difficulties: C16D1 (n=12, 109)
Values in Units on a scale · Interval/dispersion: Standard Deviation
Group
Value
Spread
Lower
Upper
Comment
Docetaxel
13.89
30.01
Not reported
Not reported
Not reported
Atezolizumab
18.65
29.20
Not reported
Not reported
Not reported
Financial Difficulties: C17D1 (n=11, 98)
Values in Units on a scale · Interval/dispersion: Standard Deviation
Group
Value
Spread
Lower
Upper
Comment
Docetaxel
15.15
22.92
Not reported
Not reported
Not reported
Atezolizumab
18.37
27.55
Not reported
Not reported
Not reported
Financial Difficulties: C18D1 (n=10, 92)
Values in Units on a scale · Interval/dispersion: Standard Deviation
Group
Value
Spread
Lower
Upper
Comment
Docetaxel
10.00
22.50
Not reported
Not reported
Not reported
Atezolizumab
19.57
28.45
Not reported
Not reported
Not reported
Financial Difficulties: C19D1 (n=9, 84)
Values in Units on a scale · Interval/dispersion: Standard Deviation
Group
Value
Spread
Lower
Upper
Comment
Docetaxel
3.70
11.11
Not reported
Not reported
Not reported
Atezolizumab
19.05
28.94
Not reported
Not reported
Not reported
Financial Difficulties: C20D1 (n=9, 80)
Values in Units on a scale · Interval/dispersion: Standard Deviation
Group
Value
Spread
Lower
Upper
Comment
Docetaxel
11.11
33.33
Not reported
Not reported
Not reported
Atezolizumab
18.75
27.99
Not reported
Not reported
Not reported
Financial Difficulties: C21D1 (n=9, 75)
Values in Units on a scale · Interval/dispersion: Standard Deviation
Group
Value
Spread
Lower
Upper
Comment
Docetaxel
11.11
33.33
Not reported
Not reported
Not reported
Atezolizumab
23.11
30.99
Not reported
Not reported
Not reported
Financial Difficulties: C22D1 (n=8, 68)
Values in Units on a scale · Interval/dispersion: Standard Deviation
Group
Value
Spread
Lower
Upper
Comment
Docetaxel
12.50
35.36
Not reported
Not reported
Not reported
Atezolizumab
18.63
28.44
Not reported
Not reported
Not reported
Financial Difficulties: C23D1 (n=7, 66)
Values in Units on a scale · Interval/dispersion: Standard Deviation
Group
Value
Spread
Lower
Upper
Comment
Docetaxel
9.52
25.20
Not reported
Not reported
Not reported
Atezolizumab
21.72
30.66
Not reported
Not reported
Not reported
Financial Difficulties: C24D1 (n=5, 64)
Values in Units on a scale · Interval/dispersion: Standard Deviation
Group
Value
Spread
Lower
Upper
Comment
Docetaxel
13.33
29.81
Not reported
Not reported
Not reported
Atezolizumab
20.83
29.99
Not reported
Not reported
Not reported
Financial Difficulties: C25D1 (n=3, 60)
Values in Units on a scale · Interval/dispersion: Standard Deviation
Group
Value
Spread
Lower
Upper
Comment
Docetaxel
0.00
0.00
Not reported
Not reported
Not reported
Atezolizumab
21.67
31.19
Not reported
Not reported
Not reported
Financial Difficulties: C26D1 (n=3, 55)
Values in Units on a scale · Interval/dispersion: Standard Deviation
Group
Value
Spread
Lower
Upper
Comment
Docetaxel
0.00
0.00
Not reported
Not reported
Not reported
Atezolizumab
20.00
30.50
Not reported
Not reported
Not reported
Financial Difficulties: C27D1 (n=3, 52)
Values in Units on a scale · Interval/dispersion: Standard Deviation
Group
Value
Spread
Lower
Upper
Comment
Docetaxel
0.00
0.00
Not reported
Not reported
Not reported
Atezolizumab
17.31
28.38
Not reported
Not reported
Not reported
Financial Difficulties: C28D1 (n=1, 48)
Values in Units on a scale · Interval/dispersion: Standard Deviation
Group
Value
Spread
Lower
Upper
Comment
Docetaxel
0.00
NA
Not reported
Not reported
Data not reported because SD was non-estimable since only 1 participant was evaluated for this category.
Atezolizumab
18.06
26.59
Not reported
Not reported
Not reported
Financial Difficulties: C29D1 (n=2, 40)
Values in Units on a scale · Interval/dispersion: Standard Deviation
Group
Value
Spread
Lower
Upper
Comment
Docetaxel
50.00
70.71
Not reported
Not reported
Not reported
Atezolizumab
19.17
28.13
Not reported
Not reported
Not reported
Financial Difficulties: C30D1 (n=1, 31)
Values in Units on a scale · Interval/dispersion: Standard Deviation
Group
Value
Spread
Lower
Upper
Comment
Docetaxel
0.00
NA
Not reported
Not reported
Data not reported because SD was non-estimable since only 1 participant was evaluated for this category.
Atezolizumab
17.20
25.63
Not reported
Not reported
Not reported
Financial Difficulties: C31D1(n=0, 24)
Values in Units on a scale · Interval/dispersion: Standard Deviation
Group
Value
Spread
Lower
Upper
Comment
Docetaxel
NA
NA
Not reported
Not reported
Data not reported because no participant was evaluated for this category
Atezolizumab
20.83
25.66
Not reported
Not reported
Not reported
Financial Difficulties: C32D1(n=0, 22)
Values in Units on a scale · Interval/dispersion: Standard Deviation
Group
Value
Spread
Lower
Upper
Comment
Docetaxel
NA
NA
Not reported
Not reported
Data not reported because no participant was evaluated for this category
Atezolizumab
21.21
26.32
Not reported
Not reported
Not reported
Financial Difficulties: C33D1(n=0, 16)
Values in Units on a scale · Interval/dispersion: Standard Deviation
Group
Value
Spread
Lower
Upper
Comment
Docetaxel
NA
NA
Not reported
Not reported
Data not reported because no participant was evaluated for this category
Atezolizumab
22.92
29.11
Not reported
Not reported
Not reported
Financial Difficulties: C34D1(n=0, 14)
Values in Units on a scale · Interval/dispersion: Standard Deviation
Group
Value
Spread
Lower
Upper
Comment
Docetaxel
NA
NA
Not reported
Not reported
Data not reported because no participant was evaluated for this category
Atezolizumab
26.19
35.03
Not reported
Not reported
Not reported
Financial Difficulties: C35D1(n=0, 12)
Values in Units on a scale · Interval/dispersion: Standard Deviation
Group
Value
Spread
Lower
Upper
Comment
Docetaxel
NA
NA
Not reported
Not reported
Data not reported because no participant was evaluated for this category
Atezolizumab
27.78
37.15
Not reported
Not reported
Not reported
Financial Difficulties: C36D1(n=0, 8)
Values in Units on a scale · Interval/dispersion: Standard Deviation
Group
Value
Spread
Lower
Upper
Comment
Docetaxel
NA
NA
Not reported
Not reported
Data not reported because no participant was evaluated for this category
Atezolizumab
8.33
15.43
Not reported
Not reported
Not reported
Financial Difficulties: C37D1(n=0, 5)
Values in Units on a scale · Interval/dispersion: Standard Deviation
Group
Value
Spread
Lower
Upper
Comment
Docetaxel
NA
NA
Not reported
Not reported
Data not reported because no participant was evaluated for this category
Atezolizumab
26.67
43.46
Not reported
Not reported
Not reported
Financial Difficulties: C38D1(n=0, 2)
Values in Units on a scale · Interval/dispersion: Standard Deviation
Group
Value
Spread
Lower
Upper
Comment
Docetaxel
NA
NA
Not reported
Not reported
Data not reported because no participant was evaluated for this category
Atezolizumab
16.67
23.57
Not reported
Not reported
Not reported
Financial Difficulties: EOT(n=263, 245)
Values in Units on a scale · Interval/dispersion: Standard Deviation
Group
Value
Spread
Lower
Upper
Comment
Docetaxel
21.80
29.23
Not reported
Not reported
Not reported
Atezolizumab
19.46
28.75
Not reported
Not reported
Not reported
Financial Difficulties: Pro Week 6 Pd (n=0, 1)
Values in Units on a scale · Interval/dispersion: Standard Deviation
Group
Value
Spread
Lower
Upper
Comment
Docetaxel
NA
NA
Not reported
Not reported
Data not reported because no participant was evaluated for this category
Atezolizumab
33.33
NA
Not reported
Not reported
Data not reported because SD was non-estimable since only 1 participant was evaluated for this category.
Financial Difficulties:Survival FU-1 (n=2,24)
Values in Units on a scale · Interval/dispersion: Standard Deviation
Group
Value
Spread
Lower
Upper
Comment
Docetaxel
83.33
23.57
Not reported
Not reported
Not reported
Atezolizumab
66.67
NA
Not reported
Not reported
Data not reported because SD was non-estimable since only 1 participant was evaluated for this category.
Insomnia: Baseline (n= 388, 413)
Values in Units on a scale · Interval/dispersion: Standard Deviation
Group
Value
Spread
Lower
Upper
Comment
Docetaxel
28.87
30.55
Not reported
Not reported
Not reported
Atezolizumab
26.15
28.72
Not reported
Not reported
Not reported
Insomnia: C2D1(n= 340, 367)
Values in Units on a scale · Interval/dispersion: Standard Deviation
Group
Value
Spread
Lower
Upper
Comment
Docetaxel
27.55
30.87
Not reported
Not reported
Not reported
Atezolizumab
26.52
28.61
Not reported
Not reported
Not reported
Insomnia: C3D1(n= 253, 304)
Values in Units on a scale · Interval/dispersion: Standard Deviation
Group
Value
Spread
Lower
Upper
Comment
Docetaxel
25.69
29.15
Not reported
Not reported
Not reported
Atezolizumab
24.89
27.32
Not reported
Not reported
Not reported
Insomnia: C4D1(n= 222, 279)
Values in Units on a scale · Interval/dispersion: Standard Deviation
Group
Value
Spread
Lower
Upper
Comment
Docetaxel
21.32
26.07
Not reported
Not reported
Not reported
Atezolizumab
23.66
26.48
Not reported
Not reported
Not reported
Insomnia: C5D1(n= 166, 237)
Values in Units on a scale · Interval/dispersion: Standard Deviation
Group
Value
Spread
Lower
Upper
Comment
Docetaxel
21.49
25.43
Not reported
Not reported
Not reported
Atezolizumab
25.88
29.84
Not reported
Not reported
Not reported
Insomnia: C6D1(n= 150, 225)
Values in Units on a scale · Interval/dispersion: Standard Deviation
Group
Value
Spread
Lower
Upper
Comment
Docetaxel
22.00
26.71
Not reported
Not reported
Not reported
Atezolizumab
23.41
27.73
Not reported
Not reported
Not reported
Insomnia: C7D1(n= 87, 189)
Values in Units on a scale · Interval/dispersion: Standard Deviation
Group
Value
Spread
Lower
Upper
Comment
Docetaxel
21.07
25.47
Not reported
Not reported
Not reported
Atezolizumab
23.99
26.65
Not reported
Not reported
Not reported
Insomnia: C8D1(n= 70, 169)
Values in Units on a scale · Interval/dispersion: Standard Deviation
Group
Value
Spread
Lower
Upper
Comment
Docetaxel
15.24
23.87
Not reported
Not reported
Not reported
Atezolizumab
23.87
26.27
Not reported
Not reported
Not reported
Insomnia: C9D1(n= 49, 153)
Values in Units on a scale · Interval/dispersion: Standard Deviation
Group
Value
Spread
Lower
Upper
Comment
Docetaxel
16.33
26.46
Not reported
Not reported
Not reported
Atezolizumab
22.88
27.16
Not reported
Not reported
Not reported
Insomnia: C10D1(n= 46, 144)
Values in Units on a scale · Interval/dispersion: Standard Deviation
Group
Value
Spread
Lower
Upper
Comment
Docetaxel
13.77
19.34
Not reported
Not reported
Not reported
Atezolizumab
21.53
26.87
Not reported
Not reported
Not reported
Insomnia: C11D1(n= 36, 133)
Values in Units on a scale · Interval/dispersion: Standard Deviation
Group
Value
Spread
Lower
Upper
Comment
Docetaxel
9.26
18.87
Not reported
Not reported
Not reported
Atezolizumab
20.55
27.44
Not reported
Not reported
Not reported
Insomnia: C12D1(n= 29, 132)
Values in Units on a scale · Interval/dispersion: Standard Deviation
Group
Value
Spread
Lower
Upper
Comment
Docetaxel
16.09
30.37
Not reported
Not reported
Not reported
Atezolizumab
21.46
24.41
Not reported
Not reported
Not reported
Insomnia: C13D1(n= 17, 124)
Values in Units on a scale · Interval/dispersion: Standard Deviation
Group
Value
Spread
Lower
Upper
Comment
Docetaxel
17.65
29.15
Not reported
Not reported
Not reported
Atezolizumab
23.39
28.51
Not reported
Not reported
Not reported
Insomnia: C14D1(n= 17, 121)
Values in Units on a scale · Interval/dispersion: Standard Deviation
Group
Value
Spread
Lower
Upper
Comment
Docetaxel
25.49
27.71
Not reported
Not reported
Not reported
Atezolizumab
23.69
26.33
Not reported
Not reported
Not reported
Insomnia: C15D1(n= 15, 113)
Values in Units on a scale · Interval/dispersion: Standard Deviation
Group
Value
Spread
Lower
Upper
Comment
Docetaxel
22.22
29.99
Not reported
Not reported
Not reported
Atezolizumab
21.53
28.84
Not reported
Not reported
Not reported
Insomnia: C16D1(n= 13, 108)
Values in Units on a scale · Interval/dispersion: Standard Deviation
Group
Value
Spread
Lower
Upper
Comment
Docetaxel
20.51
25.60
Not reported
Not reported
Not reported
Atezolizumab
21.60
31.01
Not reported
Not reported
Not reported
Insomnia: C17D1(n= 11, 98)
Values in Units on a scale · Interval/dispersion: Standard Deviation
Group
Value
Spread
Lower
Upper
Comment
Docetaxel
21.21
26.97
Not reported
Not reported
Not reported
Atezolizumab
20.07
28.21
Not reported
Not reported
Not reported
Insomnia: C18D1(n= 10, 92)
Values in Units on a scale · Interval/dispersion: Standard Deviation
Group
Value
Spread
Lower
Upper
Comment
Docetaxel
20.00
32.20
Not reported
Not reported
Not reported
Atezolizumab
21.38
27.77
Not reported
Not reported
Not reported
Insomnia: C19D1(n= 9, 83)
Values in Units on a scale · Interval/dispersion: Standard Deviation
Group
Value
Spread
Lower
Upper
Comment
Docetaxel
18.52
24.22
Not reported
Not reported
Not reported
Atezolizumab
22.49
28.09
Not reported
Not reported
Not reported
Insomnia: C20D1(n= 9, 80)
Values in Units on a scale · Interval/dispersion: Standard Deviation
Group
Value
Spread
Lower
Upper
Comment
Docetaxel
18.52
33.79
Not reported
Not reported
Not reported
Atezolizumab
20.83
29.71
Not reported
Not reported
Not reported
Insomnia: C21D1(n= 9, 75)
Values in Units on a scale · Interval/dispersion: Standard Deviation
Group
Value
Spread
Lower
Upper
Comment
Docetaxel
22.22
33.33
Not reported
Not reported
Not reported
Atezolizumab
20.89
29.90
Not reported
Not reported
Not reported
Insomnia: C22D1(n= 8, 69)
Values in Units on a scale · Interval/dispersion: Standard Deviation
Group
Value
Spread
Lower
Upper
Comment
Docetaxel
16.67
35.63
Not reported
Not reported
Not reported
Atezolizumab
18.84
26.49
Not reported
Not reported
Not reported
Insomnia: C23D1(n= 8, 66)
Values in Units on a scale · Interval/dispersion: Standard Deviation
Group
Value
Spread
Lower
Upper
Comment
Docetaxel
20.83
35.36
Not reported
Not reported
Not reported
Atezolizumab
19.70
28.03
Not reported
Not reported
Not reported
Insomnia: C24D1(n= 5, 64)
Values in Units on a scale · Interval/dispersion: Standard Deviation
Group
Value
Spread
Lower
Upper
Comment
Docetaxel
26.67
27.89
Not reported
Not reported
Not reported
Atezolizumab
19.79
25.00
Not reported
Not reported
Not reported
Insomnia: C25D1(n= 3, 60)
Values in Units on a scale · Interval/dispersion: Standard Deviation
Group
Value
Spread
Lower
Upper
Comment
Docetaxel
11.11
19.24
Not reported
Not reported
Not reported
Atezolizumab
18.89
23.26
Not reported
Not reported
Not reported
Insomnia: C26D1(n= 3, 55)
Values in Units on a scale · Interval/dispersion: Standard Deviation
Group
Value
Spread
Lower
Upper
Comment
Docetaxel
11.11
19.24
Not reported
Not reported
Not reported
Atezolizumab
21.21
27.49
Not reported
Not reported
Not reported
Insomnia: C27D1(n= 3, 52)
Values in Units on a scale · Interval/dispersion: Standard Deviation
Group
Value
Spread
Lower
Upper
Comment
Docetaxel
11.11
19.24
Not reported
Not reported
Not reported
Atezolizumab
19.23
28.27
Not reported
Not reported
Not reported
Insomnia: C28D1(n= 1, 49)
Values in Units on a scale · Interval/dispersion: Standard Deviation
Group
Value
Spread
Lower
Upper
Comment
Docetaxel
0.00
NA
Not reported
Not reported
Data not reported because SD was non-estimable since only 1 participant was evaluated for this category.
Atezolizumab
21.09
27.80
Not reported
Not reported
Not reported
Insomnia: C29D1(n= 2, 40)
Values in Units on a scale · Interval/dispersion: Standard Deviation
Group
Value
Spread
Lower
Upper
Comment
Docetaxel
33.33
47.14
Not reported
Not reported
Not reported
Atezolizumab
21.67
26.74
Not reported
Not reported
Not reported
Insomnia: C30D1(n= 1, 31)
Values in Units on a scale · Interval/dispersion: Standard Deviation
Group
Value
Spread
Lower
Upper
Comment
Docetaxel
0.00
NA
Not reported
Not reported
Data not reported because SD was non-estimable since only 1 participant was evaluated for this category.
Atezolizumab
20.43
28.12
Not reported
Not reported
Not reported
Insomnia: C31D1(n= 0, 24)
Values in Units on a scale · Interval/dispersion: Standard Deviation
Group
Value
Spread
Lower
Upper
Comment
Docetaxel
NA
NA
Not reported
Not reported
Data not reported because no participant was evaluated for this category
Atezolizumab
20.83
27.47
Not reported
Not reported
Not reported
Insomnia: C32D1(n= 0, 22)
Values in Units on a scale · Interval/dispersion: Standard Deviation
Group
Value
Spread
Lower
Upper
Comment
Docetaxel
NA
NA
Not reported
Not reported
Data not reported because no participant was evaluated for this category
Atezolizumab
19.70
26.55
Not reported
Not reported
Not reported
Insomnia: C33D1(n= 0, 16)
Values in Units on a scale · Interval/dispersion: Standard Deviation
Group
Value
Spread
Lower
Upper
Comment
Docetaxel
NA
NA
Not reported
Not reported
Data not reported because no participant was evaluated for this category
Atezolizumab
20.83
34.16
Not reported
Not reported
Not reported
Insomnia: C34D1(n= 0, 14)
Values in Units on a scale · Interval/dispersion: Standard Deviation
Group
Value
Spread
Lower
Upper
Comment
Docetaxel
NA
NA
Not reported
Not reported
Data not reported because no participant was evaluated for this category
Atezolizumab
23.81
24.21
Not reported
Not reported
Not reported
Insomnia: C35D1(n= 0, 12)
Values in Units on a scale · Interval/dispersion: Standard Deviation
Group
Value
Spread
Lower
Upper
Comment
Docetaxel
NA
NA
Not reported
Not reported
Data not reported because no participant was evaluated for this category
Atezolizumab
25.00
28.87
Not reported
Not reported
Not reported
Insomnia: C36D1(n= 0, 8)
Values in Units on a scale · Interval/dispersion: Standard Deviation
Group
Value
Spread
Lower
Upper
Comment
Docetaxel
NA
NA
Not reported
Not reported
Data not reported because no participant was evaluated for this category
Atezolizumab
25.00
23.57
Not reported
Not reported
Not reported
Insomnia: C37D1(n= 0, 5)
Values in Units on a scale · Interval/dispersion: Standard Deviation
Group
Value
Spread
Lower
Upper
Comment
Docetaxel
NA
NA
Not reported
Not reported
Data not reported because no participant was evaluated for this category
Atezolizumab
33.33
23.57
Not reported
Not reported
Not reported
Insomnia: C38D1(n= 0, 2)
Values in Units on a scale · Interval/dispersion: Standard Deviation
Group
Value
Spread
Lower
Upper
Comment
Docetaxel
NA
NA
Not reported
Not reported
Data not reported because no participant was evaluated for this category
Atezolizumab
16.67
23.57
Not reported
Not reported
Not reported
Insomnia: EOT(n= 264, 246)
Values in Units on a scale · Interval/dispersion: Standard Deviation
Group
Value
Spread
Lower
Upper
Comment
Docetaxel
28.91
30.65
Not reported
Not reported
Not reported
Atezolizumab
29.95
30.30
Not reported
Not reported
Not reported
Insomnia: Pro Week Pd(n= 0, 1)
Values in Units on a scale · Interval/dispersion: Standard Deviation
Group
Value
Spread
Lower
Upper
Comment
Docetaxel
NA
NA
Not reported
Not reported
Data not reported because no participant was evaluated for this category
Atezolizumab
66.67
NA
Not reported
Not reported
Data not reported because SD was non-estimable since only 1 participant was evaluated for this category.
Insomnia: Survival FU-1 (n= 2, 1)
Values in Units on a scale · Interval/dispersion: Standard Deviation
Group
Value
Spread
Lower
Upper
Comment
Docetaxel
50.00
70.71
Not reported
Not reported
Not reported
Atezolizumab
100.00
NA
Not reported
Not reported
Data not reported because SD was non-estimable since only 1 participant was evaluated for this category.
Dyspnea: C1D1 (n= 389, 412)
Values in Units on a scale · Interval/dispersion: Standard Deviation
Group
Value
Spread
Lower
Upper
Comment
Docetaxel
33.50
31.11
Not reported
Not reported
Not reported
Atezolizumab
32.04
28.73
Not reported
Not reported
Not reported
Dyspnea: C2D1 (n= 341, 368)
Values in Units on a scale · Interval/dispersion: Standard Deviation
Group
Value
Spread
Lower
Upper
Comment
Docetaxel
32.55
29.03
Not reported
Not reported
Not reported
Atezolizumab
31.88
29.70
Not reported
Not reported
Not reported
Dyspnea: C3D1 (n= 255, 302)
Values in Units on a scale · Interval/dispersion: Standard Deviation
Group
Value
Spread
Lower
Upper
Comment
Docetaxel
29.93
27.54
Not reported
Not reported
Not reported
Atezolizumab
27.15
26.73
Not reported
Not reported
Not reported
Dyspnea: C4D1 (n= 389, 277)
Values in Units on a scale · Interval/dispersion: Standard Deviation
Group
Value
Spread
Lower
Upper
Comment
Docetaxel
28.38
24.37
Not reported
Not reported
Not reported
Atezolizumab
28.28
27.48
Not reported
Not reported
Not reported
Dyspnea: C5D1 (n= 222, 236)
Values in Units on a scale · Interval/dispersion: Standard Deviation
Group
Value
Spread
Lower
Upper
Comment
Docetaxel
29.52
24.46
Not reported
Not reported
Not reported
Atezolizumab
27.82
27.03
Not reported
Not reported
Not reported
Dyspnea: C6D1 (n= 166, 222)
Values in Units on a scale · Interval/dispersion: Standard Deviation
Group
Value
Spread
Lower
Upper
Comment
Docetaxel
30.02
26.32
Not reported
Not reported
Not reported
Atezolizumab
26.88
25.63
Not reported
Not reported
Not reported
Dyspnea: C7D1 (n= 151, 188)
Values in Units on a scale · Interval/dispersion: Standard Deviation
Group
Value
Spread
Lower
Upper
Comment
Docetaxel
27.13
25.31
Not reported
Not reported
Not reported
Atezolizumab
25.53
25.99
Not reported
Not reported
Not reported
Dyspnea: C8D1 (n= 86, 169)
Values in Units on a scale · Interval/dispersion: Standard Deviation
Group
Value
Spread
Lower
Upper
Comment
Docetaxel
28.70
29.76
Not reported
Not reported
Not reported
Atezolizumab
26.43
26.70
Not reported
Not reported
Not reported
Dyspnea: C9D1 (n= 72, 152)
Values in Units on a scale · Interval/dispersion: Standard Deviation
Group
Value
Spread
Lower
Upper
Comment
Docetaxel
26.67
28.57
Not reported
Not reported
Not reported
Atezolizumab
24.12
24.92
Not reported
Not reported
Not reported
Dyspnea: C10D1 (n= 50, 146)
Values in Units on a scale · Interval/dispersion: Standard Deviation
Group
Value
Spread
Lower
Upper
Comment
Docetaxel
27.66
28.93
Not reported
Not reported
Not reported
Atezolizumab
23.52
23.54
Not reported
Not reported
Not reported
Dyspnea: C11D1 (n= 47, 134)
Values in Units on a scale · Interval/dispersion: Standard Deviation
Group
Value
Spread
Lower
Upper
Comment
Docetaxel
25.23
30.84
Not reported
Not reported
Not reported
Atezolizumab
22.89
25.00
Not reported
Not reported
Not reported
Dyspnea: C12D1 (n= 37, 132)
Values in Units on a scale · Interval/dispersion: Standard Deviation
Group
Value
Spread
Lower
Upper
Comment
Docetaxel
26.67
26.84
Not reported
Not reported
Not reported
Atezolizumab
22.73
25.83
Not reported
Not reported
Not reported
Dyspnea: C13D1 (n= 30, 123)
Values in Units on a scale · Interval/dispersion: Standard Deviation
Group
Value
Spread
Lower
Upper
Comment
Docetaxel
19.30
23.08
Not reported
Not reported
Not reported
Atezolizumab
25.47
26.68
Not reported
Not reported
Not reported
Dyspnea: C14D1 (n= 19, 119)
Values in Units on a scale · Interval/dispersion: Standard Deviation
Group
Value
Spread
Lower
Upper
Comment
Docetaxel
20.37
25.92
Not reported
Not reported
Not reported
Atezolizumab
21.85
25.47
Not reported
Not reported
Not reported
Dyspnea: C15D1 (n= 16, 113)
Values in Units on a scale · Interval/dispersion: Standard Deviation
Group
Value
Spread
Lower
Upper
Comment
Docetaxel
16.67
17.21
Not reported
Not reported
Not reported
Atezolizumab
22.71
24.51
Not reported
Not reported
Not reported
Dyspnea: C16D1 (n= 13, 109)
Values in Units on a scale · Interval/dispersion: Standard Deviation
Group
Value
Spread
Lower
Upper
Comment
Docetaxel
20.51
16.88
Not reported
Not reported
Not reported
Atezolizumab
21.71
25.00
Not reported
Not reported
Not reported
Dyspnea: C17D1 (n= 11, 98)
Values in Units on a scale · Interval/dispersion: Standard Deviation
Group
Value
Spread
Lower
Upper
Comment
Docetaxel
15.15
17.41
Not reported
Not reported
Not reported
Atezolizumab
21.43
23.57
Not reported
Not reported
Not reported
Dyspnea: C18D1 (n= 10, 92)
Values in Units on a scale · Interval/dispersion: Standard Deviation
Group
Value
Spread
Lower
Upper
Comment
Docetaxel
20.00
17.21
Not reported
Not reported
Not reported
Atezolizumab
22.83
25.64
Not reported
Not reported
Not reported
Dyspnea: C19D1 (n= 9, 84)
Values in Units on a scale · Interval/dispersion: Standard Deviation
Group
Value
Spread
Lower
Upper
Comment
Docetaxel
11.11
16.67
Not reported
Not reported
Not reported
Atezolizumab
23.41
23.59
Not reported
Not reported
Not reported
Dyspnea: C20D1 (n= 9, 80)
Values in Units on a scale · Interval/dispersion: Standard Deviation
Group
Value
Spread
Lower
Upper
Comment
Docetaxel
18.52
17.57
Not reported
Not reported
Not reported
Atezolizumab
21.67
24.36
Not reported
Not reported
Not reported
Dyspnea: C21D1 (n= 9, 75)
Values in Units on a scale · Interval/dispersion: Standard Deviation
Group
Value
Spread
Lower
Upper
Comment
Docetaxel
18.52
17.57
Not reported
Not reported
Not reported
Atezolizumab
19.11
20.63
Not reported
Not reported
Not reported
Dyspnea: C22D1 (n= 8, 68)
Values in Units on a scale · Interval/dispersion: Standard Deviation
Group
Value
Spread
Lower
Upper
Comment
Docetaxel
20.83
35.36
Not reported
Not reported
Not reported
Atezolizumab
20.59
23.06
Not reported
Not reported
Not reported
Dyspnea: C23D1 (n= 8, 65)
Values in Units on a scale · Interval/dispersion: Standard Deviation
Group
Value
Spread
Lower
Upper
Comment
Docetaxel
12.50
17.25
Not reported
Not reported
Not reported
Atezolizumab
18.46
21.27
Not reported
Not reported
Not reported
Dyspnea: C24D1 (n= 5, 64)
Values in Units on a scale · Interval/dispersion: Standard Deviation
Group
Value
Spread
Lower
Upper
Comment
Docetaxel
6.67
14.91
Not reported
Not reported
Not reported
Atezolizumab
19.79
24.28
Not reported
Not reported
Not reported
Dyspnea: C25D1 (n= 3, 60)
Values in Units on a scale · Interval/dispersion: Standard Deviation
Group
Value
Spread
Lower
Upper
Comment
Docetaxel
11.11
19.24
Not reported
Not reported
Not reported
Atezolizumab
20.00
22.30
Not reported
Not reported
Not reported
Dyspnea: C26D1 (n= 3, 55)
Values in Units on a scale · Interval/dispersion: Standard Deviation
Group
Value
Spread
Lower
Upper
Comment
Docetaxel
0.00
0.00
Not reported
Not reported
Not reported
Atezolizumab
20.00
24.51
Not reported
Not reported
Not reported
Dyspnea: C27D1 (n= 3, 52)
Values in Units on a scale · Interval/dispersion: Standard Deviation
Group
Value
Spread
Lower
Upper
Comment
Docetaxel
0.00
0.00
Not reported
Not reported
Not reported
Atezolizumab
16.03
19.23
Not reported
Not reported
Not reported
Dyspnea: C28D1 (n= 1, 49)
Values in Units on a scale · Interval/dispersion: Standard Deviation
Group
Value
Spread
Lower
Upper
Comment
Docetaxel
0.00
NA
Not reported
Not reported
Data not reported because SD was non-estimable since only 1 participant was evaluated for this category.
Atezolizumab
17.01
20.55
Not reported
Not reported
Not reported
Dyspnea: C29D1 (n= 2, 40)
Values in Units on a scale · Interval/dispersion: Standard Deviation
Group
Value
Spread
Lower
Upper
Comment
Docetaxel
33.33
47.14
Not reported
Not reported
Not reported
Atezolizumab
15.00
21.28
Not reported
Not reported
Not reported
Dyspnea: C30D1 (n= 1, 31)
Values in Units on a scale · Interval/dispersion: Standard Deviation
Group
Value
Spread
Lower
Upper
Comment
Docetaxel
0.00
NA
Not reported
Not reported
Data not reported because SD was non-estimable since only 1 participant was evaluated for this category.
Atezolizumab
16.13
18.99
Not reported
Not reported
Not reported
Dyspnea: C31D1 (n= 0, 24)
Values in Units on a scale · Interval/dispersion: Standard Deviation
Group
Value
Spread
Lower
Upper
Comment
Docetaxel
NA
NA
Not reported
Not reported
Data not reported because no participant was evaluated for this category
Atezolizumab
22.22
23.40
Not reported
Not reported
Not reported
Dyspnea: C32D1 (n= 0, 22)
Values in Units on a scale · Interval/dispersion: Standard Deviation
Group
Value
Spread
Lower
Upper
Comment
Docetaxel
NA
NA
Not reported
Not reported
Data not reported because no participant was evaluated for this category
Atezolizumab
22.73
21.54
Not reported
Not reported
Not reported
Dyspnea: C33D1 (n= 0, 16)
Values in Units on a scale · Interval/dispersion: Standard Deviation
Group
Value
Spread
Lower
Upper
Comment
Docetaxel
NA
NA
Not reported
Not reported
Data not reported because no participant was evaluated for this category
Atezolizumab
25.00
31.03
Not reported
Not reported
Not reported
Dyspnea: C34D1 (n= 0, 14)
Values in Units on a scale · Interval/dispersion: Standard Deviation
Group
Value
Spread
Lower
Upper
Comment
Docetaxel
NA
NA
Not reported
Not reported
Data not reported because no participant was evaluated for this category
Atezolizumab
26.19
26.73
Not reported
Not reported
Not reported
Dyspnea: C35D1 (n= 0, 12)
Values in Units on a scale · Interval/dispersion: Standard Deviation
Group
Value
Spread
Lower
Upper
Comment
Docetaxel
NA
NA
Not reported
Not reported
Data not reported because no participant was evaluated for this category
Atezolizumab
25.00
25.13
Not reported
Not reported
Not reported
Dyspnea: C36D1 (n= 0, 8)
Values in Units on a scale · Interval/dispersion: Standard Deviation
Group
Value
Spread
Lower
Upper
Comment
Docetaxel
NA
NA
Not reported
Not reported
Data not reported because no participant was evaluated for this category
Atezolizumab
20.83
17.25
Not reported
Not reported
Not reported
Dyspnea: C37D1 (n= 0, 5)
Values in Units on a scale · Interval/dispersion: Standard Deviation
Group
Value
Spread
Lower
Upper
Comment
Docetaxel
NA
NA
Not reported
Not reported
Data not reported because no participant was evaluated for this category
Atezolizumab
26.67
14.91
Not reported
Not reported
Not reported
Dyspnea: C38D1 (n= 0, 2)
Values in Units on a scale · Interval/dispersion: Standard Deviation
Group
Value
Spread
Lower
Upper
Comment
Docetaxel
NA
NA
Not reported
Not reported
Data not reported because no participant was evaluated for this category
Atezolizumab
33.33
0.00
Not reported
Not reported
Not reported
Dyspnea: EOT(n= 266, 247)
Values in Units on a scale · Interval/dispersion: Standard Deviation
Group
Value
Spread
Lower
Upper
Comment
Docetaxel
38.72
30.51
Not reported
Not reported
Not reported
Atezolizumab
39.41
32.57
Not reported
Not reported
Not reported
Dyspnea: Pro Week 6 Pd (n= 0, 1)
Values in Units on a scale · Interval/dispersion: Standard Deviation
Group
Value
Spread
Lower
Upper
Comment
Docetaxel
NA
NA
Not reported
Not reported
Data not reported because no participant was evaluated for this category
Atezolizumab
33.33
NA
Not reported
Not reported
Data not reported because SD was non-estimable since only 1 participant was evaluated for this category.
Dyspnea: Survival Follow-Up 1 (n= 2, 1)
Values in Units on a scale · Interval/dispersion: Standard Deviation
Group
Value
Spread
Lower
Upper
Comment
Docetaxel
33.33
47.14
Not reported
Not reported
Not reported
Atezolizumab
33.33
NA
Not reported
Not reported
Data not reported because SD was non-estimable since only 1 participant was evaluated for this category.
Complete source fields
classes
categories
measurements
group Id
OG000
spread
31.57
value
26.58
group Id
OG001
spread
29.41
value
22.92
title
Appetite Loss: Baseline (n= 390, 413)
categories
measurements
group Id
OG000
spread
30.39
value
27.49
group Id
OG001
spread
31.16
value
26.99
title
Appetite Loss: Cycle (C) 2 Day (D) 1(n= 342, 368)
categories
measurements
group Id
OG000
spread
28.84
value
21.35
group Id
OG001
spread
28.94
value
21.16
title
Appetite Loss: C3D1(n= 256, 304)
categories
measurements
group Id
OG000
spread
25.36
value
18.75
group Id
OG001
spread
26.60
value
18.40
title
Appetite Loss: C4D1(n= 224, 279)
categories
measurements
group Id
OG000
spread
23.89
value
18.88
group Id
OG001
spread
27.52
value
16.67
title
Appetite Loss: C5D1(n= 166, 238)
categories
measurements
group Id
OG000
spread
25.68
value
18.98
group Id
OG001
spread
25.39
value
14.88
title
Appetite Loss: C6D1(n= 151, 224)
categories
measurements
group Id
OG000
spread
24.75
value
15.91
group Id
OG001
spread
23.06
value
12.46
title
Appetite Loss: C7D1(n= 88, 190)
categories
measurements
group Id
OG000
spread
22.20
value
13.89
group Id
OG001
spread
23.27
value
12.94
title
Appetite Loss: C8D1(n= 72, 170)
categories
measurements
group Id
OG000
spread
18.52
value
8.00
group Id
OG001
spread
22.35
value
11.33
title
Appetite Loss: C9D1(n= 50, 153)
categories
measurements
group Id
OG000
spread
15.87
value
7.80
group Id
OG001
spread
21.45
value
12.33
title
Appetite Loss: C10D1(n= 47, 146)
categories
measurements
group Id
OG000
spread
23.85
value
11.71
group Id
OG001
spread
22.43
value
11.44
title
Appetite Loss: C11D1(n= 37, 134)
categories
measurements
group Id
OG000
spread
20.22
value
11.11
group Id
OG001
spread
18.81
value
8.84
title
Appetite Loss: C12D1(n= 30, 132)
denoms
counts
group Id
OG000
value
425
group Id
OG001
value
425
units
Participants
description
EORTC QLQ-C30 included global health status (GHS)/quality of life (QOL), functional scales (physical, role, cognitive, emotional, social), symptom scales (fatigue, pain, nausea/vomiting), and single items (dyspnea, appetite loss, insomnia, constipation, diarrhea, financial difficulties). Most questions from QLQ-C30 were a 4-point scale (1/Not at All to 4/Very Much), except Items 29-30, which comprise GHS scale and were a 7-point scale (1/Very Poor to 7/Excellent). For this instrument, GHS/QOL and functional scales were linearly transformed so each score ranged 0-100, where lower scores indicate poorer functioning (e.g., worsening) and higher scores indicate better functioning (e.g., improvement). Symptom scales/items were also linearly transformed so each score ranged 0-100, where higher scores indicate worse symptoms (e.g., more severe/worsened) and lower scores indicate less symptoms (e.g., less severe/improvement).
dispersion Type
Standard Deviation
groups
description
Docetaxel 75 milligrams per square meter (mg/m\^2) was administered intravenously (IV) on Day 1 of each 21-day cycle until disease progression, death, unacceptable toxicity, withdrawal of consent, or study termination by sponsor, whichever occurred first.
id
OG000
title
Docetaxel
description
Atezolizumab 1200 mg was administered IV on Day 1 of each 21-day cycle until disease progression or loss of clinical benefit, death, unacceptable toxicity, withdrawal of consent, or study termination by sponsor, whichever occurred first.
id
OG001
title
Atezolizumab
param Type
MEAN
population Description
The PP-ITT analysis set. Here, 'n' signifies those participants evaluated for this measure at specific time point for each group respectively. All 850 participants contributed to the endpoint but not all completed evaluation of every timepoint. Convention 'CxDx' refers to cycle number and day number.
reporting Status
POSTED
time Frame
Day 1 of each treatment Cycle up to EOT (up to approximately 2.25 years); 6 week following PD ( Pro Week 6 Pd) (up to approximately 2.25 years); survival follow-up-1 (up to approximately 2.25 years) (1 Cycle= 21 days)
title
EORTC QLQ Core 30 (C30) Questionnaire Score: Single Items
Triangle