Baseline characteristics

Photodynamic Therapy (PDT) For Recurrent High Grade Gliomas · Source last updated 2019-08-20

Results reported by the registry submitting party. Population, time horizon, units and missing values must be read together.

denoms

1. counts

   1. group Id

      BG000

      value

      1

   units

   Participants

groups

1. description

   Photofrin photodynamic therapy. Drug - 2.5 mg/kg, light - 240 mJ/cm2. Photofrin photodynamic therapy.: The subjects will receive a dose of 2.5 mg/kg of Photofrin intravenously 24 hours before planned surgical resection. Tumor resection will be carried out in the standard fashion in order to achieve the maximum tumor resection compatible with preservation of neurological function. After resection, Intralipid will be infused into the craniotomy and kept for approximately 45 min, while PDT will be performed. The illumination time will be calculated from the power density (mW) emitted by the laser and the radius (r) of the cavity to deliver a total light dose of 240 J/cm2 at a using the following formula: Treatment Time (sec) = Light dose (J/cm2) x Cavity surface (cm2) x 1000 Power density (mW) Cavity Surface (cm2) = 4 x 3.14 x r2 The optical fiber will be placed in the center of the surgical cavity and photoillumination will commence.

   id

   BG000

   title

   Photofrin Photodynamic Therapy.

measures

1. classes

   1. categories

      1. measurements

         1. group Id

            BG000

            value

            0

         title

         <=18 years

      2. measurements

         1. group Id

            BG000

            value

            0

         title

         Between 18 and 65 years

      3. measurements

         1. group Id

            BG000

            value

            1

         title

         >=65 years

      denoms

      1. counts

         1. group Id

            BG000

            value

            1

         units

         Participants

   param Type

   COUNT_OF_PARTICIPANTS

   title

   Age, Categorical

   unit Of Measure

   Participants

2. classes

   1. categories

      1. measurements

         1. group Id

            BG000

            value

            1

         title

         Female

      2. measurements

         1. group Id

            BG000

            value

            0

         title

         Male

      denoms

      1. counts

         1. group Id

            BG000

            value

            1

         units

         Participants

   param Type

   COUNT_OF_PARTICIPANTS

   title

   Sex: Female, Male

   unit Of Measure

   Participants

3. classes

   1. denoms

      1. counts

         1. group Id

            BG000

            value

            0

         units

         Participants

   param Type

   COUNT_OF_PARTICIPANTS

   population Description

   Race and Ethnicity were not collected from any participant.

   title

   Race and Ethnicity Not Collected

   unit Of Measure

   Participants

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Preserved source evidence · Not medical advice