Participant flow

A Study of Apalutamide (ARN-509) in Men With Non-Metastatic Castration-Resistant Prostate Cancer · Source last updated 2026-08-31

Results reported by the registry submitting party. Population, time horizon, units and missing values must be read together.

groups

1. description

   Participants received apalutamide matched placebo tablets orally on a continuous once daily dosing regimen along with androgen deprivation therapy (ADT) until disease progression, withdrawal of consent or unacceptable toxicity or death.

   id

   FG000

   title

   Placebo

2. description

   Participants received apalutamide orally at a starting dose of 240 milligram (mg) (8 x 30 mg capsules then 4 x 60 mg tablets) in a continuous treatment cycles (each treatment cycle is of 28 days) once daily dosing regimen along with androgen deprivation therapy (ADT) until disease progression, withdrawal of consent or unacceptable toxicity or death.

   id

   FG001

   title

   Apalutamide

periods

1. drop Withdraws

   1. reasons

      1. group Id

         FG000

         num Subjects

         38

      2. group Id

         FG001

         num Subjects

         59

      type

      Death

   2. reasons

      1. group Id

         FG000

         num Subjects

         37

      2. group Id

         FG001

         num Subjects

         50

      type

      Withdrawal by Subject

   3. reasons

      1. group Id

         FG000

         num Subjects

         3

      2. group Id

         FG001

         num Subjects

         7

      type

      Lost to Follow-up

   4. reasons

      1. group Id

         FG000

         num Subjects

         316

      2. group Id

         FG001

         num Subjects

         687

      type

      Ongoing

   5. reasons

      1. group Id

         FG000

         num Subjects

         7

      2. group Id

         FG001

         num Subjects

         3

      type

      Other

   milestones

   1. achievements

      1. group Id

         FG000

         num Subjects

         401

      2. group Id

         FG001

         num Subjects

         806

      type

      STARTED

   2. achievements

      1. group Id

         FG000

         num Subjects

         398

      2. group Id

         FG001

         num Subjects

         803

      type

      Treated

   3. achievements

      1. group Id

         FG000

         num Subjects

         0

      2. group Id

         FG001

         num Subjects

         0

      type

      COMPLETED

   4. achievements

      1. group Id

         FG000

         num Subjects

         401

      2. group Id

         FG001

         num Subjects

         806

      type

      NOT COMPLETED

   title

   Overall Study

Download exact source JSON → · Snapshot ctgov-results-191f4516d4760045304b24a0

Preserved source evidence · Not medical advice