TriangleNCT01869777 · OUTCOME
Number of Participants With Bone Marrow Response
Results reported by the registry submitting party. Population, time horizon, units and missing values must be read together.
- Measure
- COUNT_OF_PARTICIPANTS
- Unit
- Participants
- Interval / dispersion
- Not reported
- Time frame
- 14 days
What was measured
Logistic regression will be used to analyze the significant association between standardized phase angle and marrow response at 14-day bone marrow biopsy to show the odds of having 14-day residual disease (presence cancer cells remaining after treatment) and non-residual disease (no cancer cells remaining after treatment). (14 day bone marrow response is defined as hypoplastic marrow with less than 20% cellularity and 5% blasts. Complete remission is defined as less than 5% marrow blasts, absolute neutrophil count \>1000, platelet count \>100,000 and freedom from red cell transfusions).
Analysis population: 14 participants excluded in analysis due to 14-day bone marrow data not available.
Groups in this outcome
Diagnostic (Bioelectric Impedance Analysis)
Patients undergo bioelectrical impedance phase angle measurement on day 1 of treatment. Patients with AML undergo a second measurement just prior to the nadir marrow. Patients also undergo bioelectrical impedance measurements prior to any invasive procedures (bone marrow biopsy, leukapheresis, PICC line placement, etc.). bioelectric impedance analysis: Undergo bioelectric impedance analysis
| Group | Source count |
|---|---|
| Diagnostic (Bioelectric Impedance Analysis) | 87 |
Reported measurements
Source class 1
Residual disease
| Group | Value | Spread | Lower | Upper | Comment |
|---|---|---|---|---|---|
| Diagnostic (Bioelectric Impedance Analysis) | 47 | Not reported | Not reported | Not reported | Not reported |
No residual disease
| Group | Value | Spread | Lower | Upper | Comment |
|---|---|---|---|---|---|
| Diagnostic (Bioelectric Impedance Analysis) | 40 | Not reported | Not reported | Not reported | Not reported |
Complete source fields
- classes
- categories
- measurements
- group Id
- OG000
- value
- 47
- title
- Residual disease
- measurements
- group Id
- OG000
- value
- 40
- title
- No residual disease
- denoms
- counts
- group Id
- OG000
- value
- 87
- units
- Participants
- description
- Logistic regression will be used to analyze the significant association between standardized phase angle and marrow response at 14-day bone marrow biopsy to show the odds of having 14-day residual disease (presence cancer cells remaining after treatment) and non-residual disease (no cancer cells remaining after treatment). (14 day bone marrow response is defined as hypoplastic marrow with less than 20% cellularity and 5% blasts. Complete remission is defined as less than 5% marrow blasts, absolute neutrophil count \>1000, platelet count \>100,000 and freedom from red cell transfusions).
- groups
- description
- Patients undergo bioelectrical impedance phase angle measurement on day 1 of treatment. Patients with AML undergo a second measurement just prior to the nadir marrow. Patients also undergo bioelectrical impedance measurements prior to any invasive procedures (bone marrow biopsy, leukapheresis, PICC line placement, etc.). bioelectric impedance analysis: Undergo bioelectric impedance analysis
- id
- OG000
- title
- Diagnostic (Bioelectric Impedance Analysis)
- param Type
- COUNT_OF_PARTICIPANTS
- population Description
- 14 participants excluded in analysis due to 14-day bone marrow data not available.
- reporting Status
- POSTED
- time Frame
- 14 days
- title
- Number of Participants With Bone Marrow Response
- type
- SECONDARY
- unit Of Measure
- Participants
Download exact source JSON → · Snapshot ctgov-results-25a395029948b04d52b1253f
Preserved source evidence · Not medical advice