TriangleNCT01716208 · OUTCOME
Percent Reduction in Complement Levels (CH50)
Results reported by the registry submitting party. Population, time horizon, units and missing values must be read together.
- Measure
- MEAN
- Unit
- Percentage change
- Interval / dispersion
- Full Range
- Time frame
- Up to two weeks
What was measured
Complement CH50 is a blood test that helps us determine whether protein abnormalities and deficiencies in the complement system are responsible for any increase in autoimmune activity.
Groups in this outcome
Ofatumumab + Fresh Frozen Plasma
Ofatumumab will be infused intravenously on day 1 (300 mg initial dose), followed one week later by 2000 mg weekly for 7 doses, followed 4 weeks later by 2000 mg every 4 weeks for 4 doses. Two units (approximately 200 or 250 ml) of FFP will be administered prior to ofatumumab(with the exception of the first dose). A unit of fresh frozen plasma is approximately 250ml (or half a pint). Ofatumumab + Fresh Frozen Plasma
| Group | Source count |
|---|---|
| Ofatumumab + Fresh Frozen Plasma | 12 |
Reported measurements
Source class 1
| Group | Value | Spread | Lower | Upper | Comment |
|---|---|---|---|---|---|
| Ofatumumab + Fresh Frozen Plasma | 54 | Not reported | 20 | 100 | Not reported |
Complete source fields
- classes
- categories
- measurements
- group Id
- OG000
- lower Limit
- 20
- upper Limit
- 100
- value
- 54
- denoms
- counts
- group Id
- OG000
- value
- 12
- units
- Participants
- description
- Complement CH50 is a blood test that helps us determine whether protein abnormalities and deficiencies in the complement system are responsible for any increase in autoimmune activity.
- dispersion Type
- Full Range
- groups
- description
- Ofatumumab will be infused intravenously on day 1 (300 mg initial dose), followed one week later by 2000 mg weekly for 7 doses, followed 4 weeks later by 2000 mg every 4 weeks for 4 doses. Two units (approximately 200 or 250 ml) of FFP will be administered prior to ofatumumab(with the exception of the first dose). A unit of fresh frozen plasma is approximately 250ml (or half a pint). Ofatumumab + Fresh Frozen Plasma
- id
- OG000
- title
- Ofatumumab + Fresh Frozen Plasma
- param Type
- MEAN
- reporting Status
- POSTED
- time Frame
- Up to two weeks
- title
- Percent Reduction in Complement Levels (CH50)
- type
- SECONDARY
- unit Of Measure
- Percentage change
Download exact source JSON → · Snapshot ctgov-results-25a395029948b04d52b1253f
Preserved source evidence · Not medical advice