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NCT01675141 · OUTCOME

Expression of Cereblon (CRBN) and How it Relates to Natural Killer (NK) Cell Number and Activity

Lenalidomide Maintenance Therapy for Multiple Myeloma · Source last updated 2018-02-05

Results reported by the registry submitting party. Population, time horizon, units and missing values must be read together.

Measure
Not reported
Unit
Not reported
Interval / dispersion
Not reported
Time frame
participants were followed for the duration of their treatment, an average of 2 years

What was measured

Relative fold change in CRBN and correlation (R2) to NK cell number and activity.

Analysis population: This outcome was not done because this study was closed prior to full enrollment. Given study closure, the primary endpoint could not be and was not evaluated. There was not an adequate amount of specimens collected to arrive to any analyses conclusions.

Groups in this outcome

Lenalidomide Maintenance Therapy for Multiple Myeloma

10 mg oral daily, on days 1-21 of repeated 28 day cycles, to continue until disease progression or unacceptable toxicity. Lenalidomide: 10 mg oral daily, on days 1-21 of repeated 28 day cycles, to continue until disease progression or unacceptable toxicity.

Group identifiers and denominators belong to this outcome only. They may differ in another outcome or in safety reporting.

Analysis denominator · Participants

GroupSource count
Lenalidomide Maintenance Therapy for Multiple Myeloma0

Reported measurements

No numerical measurement classes were posted for this outcome. Missing is not zero.

Complete source fields
denoms
  1. counts
    1. group Id
      OG000
      value
      0
    units
    Participants
description
Relative fold change in CRBN and correlation (R2) to NK cell number and activity.
groups
  1. description
    10 mg oral daily, on days 1-21 of repeated 28 day cycles, to continue until disease progression or unacceptable toxicity. Lenalidomide: 10 mg oral daily, on days 1-21 of repeated 28 day cycles, to continue until disease progression or unacceptable toxicity.
    id
    OG000
    title
    Lenalidomide Maintenance Therapy for Multiple Myeloma
population Description
This outcome was not done because this study was closed prior to full enrollment. Given study closure, the primary endpoint could not be and was not evaluated. There was not an adequate amount of specimens collected to arrive to any analyses conclusions.
reporting Status
POSTED
time Frame
participants were followed for the duration of their treatment, an average of 2 years
title
Expression of Cereblon (CRBN) and How it Relates to Natural Killer (NK) Cell Number and Activity
type
SECONDARY

Download exact source JSON → · Snapshot ctgov-results-25a395029948b04d52b1253f

Preserved source evidence · Not medical advice