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NCT01445080 · OUTCOME

Plasma Inhibitory Activity (PIA)

Sorafenib in Treating Young Patients With Relapsed or Refractory Solid Tumors or Leukemia · Source last updated 2021-02-02

Results reported by the registry submitting party. Population, time horizon, units and missing values must be read together.

Measure
COUNT_OF_PARTICIPANTS
Unit
Participants
Interval / dispersion
Not reported
Time frame
1 week prior to enrollment and then every 28 days

What was measured

Analyze the plasma inhibitory activity (PIA) for FLT3 phosphorylation in peripheral blood samples obtained at the time of PK studies in patients with FLT3-ITD mutation AML (Part C).

Groups in this outcome

Part C: Refractory AML With FLT3-ITD Mutation:150 mg/m^2

Patients receive oral sorafenib 150 mg/m\^2 every 12 hours.

Group identifiers and denominators belong to this outcome only. They may differ in another outcome or in safety reporting.

Analysis denominator · Participants

GroupSource count
Part C: Refractory AML With FLT3-ITD Mutation:150 mg/m^25

Reported measurements

Source class 1
Values in Participants · Interval/dispersion: Not reported
GroupValueSpreadLowerUpperComment
Part C: Refractory AML With FLT3-ITD Mutation:150 mg/m^25Not reportedNot reportedNot reportedNot reported
Complete source fields
classes
  1. categories
    1. measurements
      1. group Id
        OG000
        value
        5
denoms
  1. counts
    1. group Id
      OG000
      value
      5
    units
    Participants
description
Analyze the plasma inhibitory activity (PIA) for FLT3 phosphorylation in peripheral blood samples obtained at the time of PK studies in patients with FLT3-ITD mutation AML (Part C).
groups
  1. description
    Patients receive oral sorafenib 150 mg/m\^2 every 12 hours.
    id
    OG000
    title
    Part C: Refractory AML With FLT3-ITD Mutation:150 mg/m^2
param Type
COUNT_OF_PARTICIPANTS
reporting Status
POSTED
time Frame
1 week prior to enrollment and then every 28 days
title
Plasma Inhibitory Activity (PIA)
type
SECONDARY
unit Of Measure
Participants

Download exact source JSON → · Snapshot ctgov-results-25a395029948b04d52b1253f

Preserved source evidence · Not medical advice