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NCT01431209 · OUTCOME

Overall Response Rate

Ruxolitinib Phosphate to Treat Diffuse Large B-Cell or Peripheral T-Cell Non-Hodgkin Lymphoma After Stem Cell Transplant · Source last updated 2023-10-05

Results reported by the registry submitting party. Population, time horizon, units and missing values must be read together.

Measure
COUNT_OF_PARTICIPANTS
Unit
Participants
Interval / dispersion
Not reported
Time frame
24 weeks

What was measured

Number of patients achieving overall response rate

Groups in this outcome

Diffuse Large B-cell Lymphoma (DLBCL)

Patients receive ruxolitinib phosphate PO BID on days 1-28. Courses repeat every 28 days in the absence of disease progression or unacceptable toxicity. Laboratory Biomarker Analysis: Correlative studies Ruxolitinib Phosphate: Given PO

Peripheral T-cell Non-Hodgkin Lymphoma (PTCL)

Patients receive ruxolitinib phosphate PO BID on days 1-28. Courses repeat every 28 days in the absence of disease progression or unacceptable toxicity. Laboratory Biomarker Analysis: Correlative studies Ruxolitinib Phosphate: Given PO

Group identifiers and denominators belong to this outcome only. They may differ in another outcome or in safety reporting.

Analysis denominator · Participants

GroupSource count
Diffuse Large B-cell Lymphoma (DLBCL)47
Peripheral T-cell Non-Hodgkin Lymphoma (PTCL)13

Reported measurements

Source class 1

Complete Response

Values in Participants · Interval/dispersion: Not reported
GroupValueSpreadLowerUpperComment
Diffuse Large B-cell Lymphoma (DLBCL)1Not reportedNot reportedNot reportedNot reported
Peripheral T-cell Non-Hodgkin Lymphoma (PTCL)1Not reportedNot reportedNot reportedNot reported

Partial Response

Values in Participants · Interval/dispersion: Not reported
GroupValueSpreadLowerUpperComment
Diffuse Large B-cell Lymphoma (DLBCL)3Not reportedNot reportedNot reportedNot reported
Peripheral T-cell Non-Hodgkin Lymphoma (PTCL)1Not reportedNot reportedNot reportedNot reported

Stable disease

Values in Participants · Interval/dispersion: Not reported
GroupValueSpreadLowerUpperComment
Diffuse Large B-cell Lymphoma (DLBCL)5Not reportedNot reportedNot reportedNot reported
Peripheral T-cell Non-Hodgkin Lymphoma (PTCL)3Not reportedNot reportedNot reportedNot reported

Progressive disease

Values in Participants · Interval/dispersion: Not reported
GroupValueSpreadLowerUpperComment
Diffuse Large B-cell Lymphoma (DLBCL)34Not reportedNot reportedNot reportedNot reported
Peripheral T-cell Non-Hodgkin Lymphoma (PTCL)7Not reportedNot reportedNot reportedNot reported

Not assessed

Values in Participants · Interval/dispersion: Not reported
GroupValueSpreadLowerUpperComment
Diffuse Large B-cell Lymphoma (DLBCL)4Not reportedNot reportedNot reportedNot reported
Peripheral T-cell Non-Hodgkin Lymphoma (PTCL)1Not reportedNot reportedNot reportedNot reported
Complete source fields
classes
  1. categories
    1. measurements
      1. group Id
        OG000
        value
        1
      2. group Id
        OG001
        value
        1
      title
      Complete Response
    2. measurements
      1. group Id
        OG000
        value
        3
      2. group Id
        OG001
        value
        1
      title
      Partial Response
    3. measurements
      1. group Id
        OG000
        value
        5
      2. group Id
        OG001
        value
        3
      title
      Stable disease
    4. measurements
      1. group Id
        OG000
        value
        34
      2. group Id
        OG001
        value
        7
      title
      Progressive disease
    5. measurements
      1. group Id
        OG000
        value
        4
      2. group Id
        OG001
        value
        1
      title
      Not assessed
denoms
  1. counts
    1. group Id
      OG000
      value
      47
    2. group Id
      OG001
      value
      13
    units
    Participants
description
Number of patients achieving overall response rate
groups
  1. description
    Patients receive ruxolitinib phosphate PO BID on days 1-28. Courses repeat every 28 days in the absence of disease progression or unacceptable toxicity. Laboratory Biomarker Analysis: Correlative studies Ruxolitinib Phosphate: Given PO
    id
    OG000
    title
    Diffuse Large B-cell Lymphoma (DLBCL)
  2. description
    Patients receive ruxolitinib phosphate PO BID on days 1-28. Courses repeat every 28 days in the absence of disease progression or unacceptable toxicity. Laboratory Biomarker Analysis: Correlative studies Ruxolitinib Phosphate: Given PO
    id
    OG001
    title
    Peripheral T-cell Non-Hodgkin Lymphoma (PTCL)
param Type
COUNT_OF_PARTICIPANTS
reporting Status
POSTED
time Frame
24 weeks
title
Overall Response Rate
type
PRIMARY
unit Of Measure
Participants

Download exact source JSON → · Snapshot ctgov-results-25a395029948b04d52b1253f

Preserved source evidence · Not medical advice