TriangleNCT01286077 · OUTCOME
Change From Baseline in Biochemical Bone Markers: Carboxyterminal Collagen Crosslinks (CTX-I)
Results reported by the registry submitting party. Population, time horizon, units and missing values must be read together.
- Measure
- MEAN
- Unit
- Nanogram per liter
- Interval / dispersion
- Standard Deviation
- Time frame
- Baseline up to end of study (approximately 4 years 7 months)
What was measured
Change from Baseline in Biochemical Bone Markers: CTX-I was assessed
Analysis population: FAS was used for analysis. "N" (number of subjects analyzed) signifies the subjects evaluable this measure and n=number pf participants analysed for this outcome measure at specific time point. Missing data was imputed by last observation carried forward (LOCF) method.
Groups in this outcome
Bortezomib
bortezomib (Velcade) 1.6 mg/m² bolus injection on Days 1, 8, 15 and 22 every 5 weeks for 4 cycles
Non-treated Control
no treatment, observation only
| Group | Source count |
|---|---|
| Bortezomib | 42 |
| Non-treated Control | 40 |
Reported measurements
Source class 1
| Group | Value | Spread | Lower | Upper | Comment |
|---|---|---|---|---|---|
| Bortezomib | -66.50 | 258.26 | Not reported | Not reported | Not reported |
| Non-treated Control | -77.68 | 158.23 | Not reported | Not reported | Not reported |
Complete source fields
- classes
- categories
- measurements
- group Id
- OG000
- spread
- 258.26
- value
- -66.50
- group Id
- OG001
- spread
- 158.23
- value
- -77.68
- denoms
- counts
- group Id
- OG000
- value
- 42
- group Id
- OG001
- value
- 40
- units
- Participants
- description
- Change from Baseline in Biochemical Bone Markers: CTX-I was assessed
- dispersion Type
- Standard Deviation
- groups
- description
- bortezomib (Velcade) 1.6 mg/m² bolus injection on Days 1, 8, 15 and 22 every 5 weeks for 4 cycles
- id
- OG000
- title
- Bortezomib
- description
- no treatment, observation only
- id
- OG001
- title
- Non-treated Control
- param Type
- MEAN
- population Description
- FAS was used for analysis. "N" (number of subjects analyzed) signifies the subjects evaluable this measure and n=number pf participants analysed for this outcome measure at specific time point. Missing data was imputed by last observation carried forward (LOCF) method.
- reporting Status
- POSTED
- time Frame
- Baseline up to end of study (approximately 4 years 7 months)
- title
- Change From Baseline in Biochemical Bone Markers: Carboxyterminal Collagen Crosslinks (CTX-I)
- type
- SECONDARY
- unit Of Measure
- Nanogram per liter
Download exact source JSON → · Snapshot ctgov-results-25a395029948b04d52b1253f
Preserved source evidence · Not medical advice