NCT01237054 · OUTCOME

Comparison of Serum Angiogenic Marker Reverse Contrast Transfer Rate (Kep) Between MGUS and SMM/MM Groups

Imaging in MGUS, SMM and MM · Source last updated 2026-02-06

Results reported by the registry submitting party. Population, time horizon, units and missing values must be read together.

Measure: MEAN
Unit: per min
Interval / dispersion: Standard Error
Time frame: 60 days

What was measured

Pharmacokinetic parameter Kep was measured by dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI).

Analysis population: Serum was not available for three patients in the SMM group.

Groups in this outcome

MGUS (Monoclonal Gammopathy of Undetermined Significance)

MGUS (Monoclonal gammopathy of undetermined significance) is a premalignant plasma cell proliferative disorder.

SMM (Smoldering Multiple Myeloma)/MM (Multiple Myeloma)

Smoldering multiple myeloma (SMM)is a premalignant plasma cell proliferative disorder. Multiple myeloma is a plasma cell neoplasm.

Group identifiers and denominators belong to this outcome only. They may differ in another outcome or in safety reporting.

Analysis denominator · Participants

Group	Source count
MGUS (Monoclonal Gammopathy of Undetermined Significance)	10
SMM (Smoldering Multiple Myeloma)/MM (Multiple Myeloma)	17

Reported measurements

Source class 1

Values in per min · Interval/dispersion: Standard Error
Group	Value	Spread	Lower	Upper	Comment
MGUS (Monoclonal Gammopathy of Undetermined Significance)	4.05	0.73	Not reported	Not reported	Not reported
SMM (Smoldering Multiple Myeloma)/MM (Multiple Myeloma)	6.93	0.97	Not reported	Not reported	Not reported

Source statistical analyses

Group order, estimate direction, methods and comments are retained. No treatment ranking is inferred.

group Ids
OG000
OG001
non Inferiority Type
SUPERIORITY
p Value
0.08
statistical Method
Wilcoxon rank sum test

Complete source fields

analyses

group Ids
OG000
OG001
non Inferiority Type
SUPERIORITY
p Value
0.08
statistical Method
Wilcoxon rank sum test

classes

categories
measurements
group Id
OG000
spread
0.73
value
4.05
group Id
OG001
spread
0.97
value
6.93

denoms

counts
group Id
OG000
value
10
group Id
OG001
value
17
units
Participants

description

Pharmacokinetic parameter Kep was measured by dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI).

dispersion Type

Standard Error

groups

description
MGUS (Monoclonal gammopathy of undetermined significance) is a premalignant plasma cell proliferative disorder.
id
OG000
title
MGUS (Monoclonal Gammopathy of Undetermined Significance)
description
Smoldering multiple myeloma (SMM)is a premalignant plasma cell proliferative disorder. Multiple myeloma is a plasma cell neoplasm.
id
OG001
title
SMM (Smoldering Multiple Myeloma)/MM (Multiple Myeloma)

param Type

MEAN

population Description

Serum was not available for three patients in the SMM group.

reporting Status

POSTED

time Frame

60 days

title

Comparison of Serum Angiogenic Marker Reverse Contrast Transfer Rate (Kep) Between MGUS and SMM/MM Groups

type

SECONDARY

unit Of Measure

per min

Download exact source JSON → · Snapshot ctgov-results-25a395029948b04d52b1253f

Preserved source evidence · Not medical advice