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NCT01236053 · BASELINE

Baseline characteristics

Cancer in Patients With Gabapentin (GPRD) · Source last updated 2017-07-06

Results reported by the registry submitting party. Population, time horizon, units and missing values must be read together.

denoms
  1. counts
    1. group Id
      BG000
      value
      179138
    2. group Id
      BG001
      value
      1710950
    3. group Id
      BG002
      value
      1877
    4. group Id
      BG003
      value
      17853
    5. group Id
      BG004
      value
      212
    6. group Id
      BG005
      value
      2067
    7. group Id
      BG006
      value
      10855
    8. group Id
      BG007
      value
      102836
    9. group Id
      BG008
      value
      300
    10. group Id
      BG009
      value
      2935
    11. group Id
      BG010
      value
      19564
    12. group Id
      BG011
      value
      188924
    units
    Participants
groups
  1. description
    Incidence of all cancers defined as first time incident cancer diagnosis (READ/Oxford Medical Information System \[OXMIS\] codes) in the General Practice Research Database (GPRD) study cohort. Entry into the study cohort began January 1, 1993, or at the time of GPRD registration if after January 1, 1993. Follow-up ended December 31, 2008, or earlier if the respective cancer was diagnosed or if the participant left the GPRD for any reason including death. Participants with a prior history of cancer were excluded.
    id
    BG000
    title
    All-Cancer: Cases
  2. description
    Cancer cases were risk set matched with up to 10 controls for sex, age at GPRD study cohort entry (within two years), calendar year of cohort entry (within one year), and General Practice site. The index date for controls was set as the date at which the follow-up time from cohort entry was the same as the case. The index date was chosen so as to give the control equal follow-up time to that of the case for ascertainment of use of gabapentin. Participants with a history of cancer prior to the index date were excluded as controls.
    id
    BG001
    title
    All-Cancer: Controls
  3. description
    Incidence of stomach cancer defined as first time incident cancer diagnosis (READ/Oxford Medical Information System \[OXMIS\] codes) in the General Practice Research Database (GPRD) study cohort. Entry into the study cohort began January 1, 1993, or at the time of GPRD registration if after January 1, 1993. Follow-up ended December 31, 2008, or earlier if the respective cancer was diagnosed or if the participant left the GPRD for any reason including death. Participants with a prior history of cancer were excluded.
    id
    BG002
    title
    Stomach Cancer: Cases
  4. description
    Cancer cases were risk set matched with up to 10 controls for sex, age at GPRD study cohort entry (within two years), calendar year of cohort entry (within one year), and General Practice site. The index date for controls was set as the date at which the follow-up time from cohort entry was the same as the case. The index date was chosen so as to give the control equal follow-up time to that of the case for ascertainment of use of gabapentin. Participants with a history of cancer prior to the index date were excluded as controls.
    id
    BG003
    title
    Stomach Cancer: Controls
  5. description
    Incidence of anal cancer defined as first time incident cancer diagnosis (READ/Oxford Medical Information System \[OXMIS\] codes) in the General Practice Research Database (GPRD) study cohort. Entry into the study cohort began January 1, 1993, or at the time of GPRD registration if after January 1, 1993. Follow-up ended December 31, 2008, or earlier if the respective cancer was diagnosed or if the participant left the GPRD for any reason including death. Participants with a prior history of cancer were excluded.
    id
    BG004
    title
    Anal Cancer: Cases
  6. description
    Cancer cases were risk set matched with up to 10 controls for sex, age at GPRD study cohort entry (within two years), calendar year of cohort entry (within one year), and General Practice site. The index date for controls was set as the date at which the follow-up time from cohort entry was the same as the case. The index date was chosen so as to give the control equal follow-up time to that of the case for ascertainment of use of gabapentin. Participants with a history of cancer prior to the index date were excluded as controls.
    id
    BG005
    title
    Anal Cancer: Controls
  7. description
    Incidence of lung cancer defined as first time incident cancer diagnosis (READ/Oxford Medical Information System \[OXMIS\] codes) in the General Practice Research Database (GPRD) study cohort. Entry into the study cohort began January 1, 1993, or at the time of GPRD registration if after January 1, 1993. Follow-up ended December 31, 2008, or earlier if the respective cancer was diagnosed or if the participant left the GPRD for any reason including death. Participants with a prior history of cancer were excluded.
    id
    BG006
    title
    Lung Cancer: Cases
  8. description
    Cancer cases were risk set matched with up to 10 controls for sex, age at GPRD study cohort entry (within two years), calendar year of cohort entry (within one year), and General Practice site. The index date for controls was set as the date at which the follow-up time from cohort entry was the same as the case. The index date was chosen so as to give the control equal follow-up time to that of the case for ascertainment of use of gabapentin. Participants with a history of cancer prior to the index date were excluded as controls.
    id
    BG007
    title
    Lung Cancer: Controls
  9. description
    Incidence of bone/joint cancer defined as first time incident cancer diagnosis (READ/Oxford Medical Information System \[OXMIS\] codes) in the General Practice Research Database (GPRD) study cohort. Entry into the study cohort began January 1, 1993, or at the time of GPRD registration if after January 1, 1993. Follow-up ended December 31, 2008, or earlier if the respective cancer was diagnosed or if the participant left the GPRD for any reason including death. Participants with a prior history of cancer were excluded.
    id
    BG008
    title
    Bone/Joint Cancer: Cases
  10. description
    Cancer cases were risk set matched with up to 10 controls for sex, age at GPRD study cohort entry (within two years), calendar year of cohort entry (within one year), and General Practice site. The index date for controls was set as the date at which the follow-up time from cohort entry was the same as the case. The index date was chosen so as to give the control equal follow-up time to that of the case for ascertainment of use of gabapentin. Participants with a history of cancer prior to the index date were excluded as controls.
    id
    BG009
    title
    Bone/Joint Cancer: Controls
  11. description
    Incidence of breast cancer defined as first time incident cancer diagnosis (READ/Oxford Medical Information System \[OXMIS\] codes) in the General Practice Research Database (GPRD) study cohort. Entry into the study cohort began January 1, 1993, or at the time of GPRD registration if after January 1, 1993. Follow-up ended December 31, 2008, or earlier if the respective cancer was diagnosed or if the participant left the GPRD for any reason including death. Participants with a prior history of cancer were excluded.
    id
    BG010
    title
    Breast Cancer: Cases
  12. description
    Cancer cases were risk set matched with up to 10 controls for sex, age at GPRD study cohort entry (within two years), calendar year of cohort entry (within one year), and General Practice site. The index date for controls was set as the date at which the follow-up time from cohort entry was the same as the case. The index date was chosen so as to give the control equal follow-up time to that of the case for ascertainment of use of gabapentin. Participants with a history of cancer prior to the index date were excluded as controls.
    id
    BG011
    title
    Breast Cancer: Controls
measures
  1. classes
    1. categories
      1. measurements
        1. group Id
          BG000
          value
          10246
        2. group Id
          BG001
          value
          101968
        3. group Id
          BG002
          value
          16
        4. group Id
          BG003
          value
          155
        5. group Id
          BG004
          value
          12
        6. group Id
          BG005
          value
          118
        7. group Id
          BG006
          value
          36
        8. group Id
          BG007
          value
          369
        9. group Id
          BG008
          value
          120
        10. group Id
          BG009
          value
          1173
        11. group Id
          BG010
          value
          915
        12. group Id
          BG011
          value
          9346
      title
      < 40 years
    2. categories
      1. measurements
        1. group Id
          BG000
          value
          13112
        2. group Id
          BG001
          value
          132244
        3. group Id
          BG002
          value
          48
        4. group Id
          BG003
          value
          469
        5. group Id
          BG004
          value
          18
        6. group Id
          BG005
          value
          200
        7. group Id
          BG006
          value
          294
        8. group Id
          BG007
          value
          2973
        9. group Id
          BG008
          value
          21
        10. group Id
          BG009
          value
          254
        11. group Id
          BG010
          value
          2827
        12. group Id
          BG011
          value
          29167
      title
      40-49 years
    3. categories
      1. measurements
        1. group Id
          BG000
          value
          28392
        2. group Id
          BG001
          value
          279797
        3. group Id
          BG002
          value
          135
        4. group Id
          BG003
          value
          1388
        5. group Id
          BG004
          value
          47
        6. group Id
          BG005
          value
          467
        7. group Id
          BG006
          value
          1256
        8. group Id
          BG007
          value
          12388
        9. group Id
          BG008
          value
          46
        10. group Id
          BG009
          value
          422
        11. group Id
          BG010
          value
          5319
        12. group Id
          BG011
          value
          51266
      title
      50-59 years
    4. categories
      1. measurements
        1. group Id
          BG000
          value
          43077
        2. group Id
          BG001
          value
          415567
        3. group Id
          BG002
          value
          395
        4. group Id
          BG003
          value
          3850
        5. group Id
          BG004
          value
          45
        6. group Id
          BG005
          value
          464
        7. group Id
          BG006
          value
          2944
        8. group Id
          BG007
          value
          28526
        9. group Id
          BG008
          value
          38
        10. group Id
          BG009
          value
          360
        11. group Id
          BG010
          value
          4665
        12. group Id
          BG011
          value
          44769
      title
      60-69 years
    5. categories
      1. measurements
        1. group Id
          BG000
          value
          50072
        2. group Id
          BG001
          value
          475887
        3. group Id
          BG002
          value
          679
        4. group Id
          BG003
          value
          6559
        5. group Id
          BG004
          value
          50
        6. group Id
          BG005
          value
          440
        7. group Id
          BG006
          value
          4092
        8. group Id
          BG007
          value
          38557
        9. group Id
          BG008
          value
          51
        10. group Id
          BG009
          value
          501
        11. group Id
          BG010
          value
          3334
        12. group Id
          BG011
          value
          32051
      title
      70-79 years
    6. categories
      1. measurements
        1. group Id
          BG000
          value
          34239
        2. group Id
          BG001
          value
          305487
        3. group Id
          BG002
          value
          604
        4. group Id
          BG003
          value
          5432
        5. group Id
          BG004
          value
          40
        6. group Id
          BG005
          value
          378
        7. group Id
          BG006
          value
          2233
        8. group Id
          BG007
          value
          20023
        9. group Id
          BG008
          value
          24
        10. group Id
          BG009
          value
          225
        11. group Id
          BG010
          value
          2504
        12. group Id
          BG011
          value
          22325
      title
      80+ years
    param Type
    NUMBER
    title
    Age, Customized
    unit Of Measure
    participants
  2. classes
    1. categories
      1. measurements
        1. group Id
          BG000
          value
          92099
        2. group Id
          BG001
          value
          883331
        3. group Id
          BG002
          value
          716
        4. group Id
          BG003
          value
          6789
        5. group Id
          BG004
          value
          133
        6. group Id
          BG005
          value
          1294
        7. group Id
          BG006
          value
          4259
        8. group Id
          BG007
          value
          40345
        9. group Id
          BG008
          value
          156
        10. group Id
          BG009
          value
          1538
        11. group Id
          BG010
          value
          19564
        12. group Id
          BG011
          value
          188924
        title
        Female
      2. measurements
        1. group Id
          BG000
          value
          87039
        2. group Id
          BG001
          value
          827619
        3. group Id
          BG002
          value
          1161
        4. group Id
          BG003
          value
          11064
        5. group Id
          BG004
          value
          79
        6. group Id
          BG005
          value
          773
        7. group Id
          BG006
          value
          6596
        8. group Id
          BG007
          value
          62491
        9. group Id
          BG008
          value
          144
        10. group Id
          BG009
          value
          1397
        11. group Id
          BG010
          value
          0
        12. group Id
          BG011
          value
          0
        title
        Male
    param Type
    COUNT_OF_PARTICIPANTS
    title
    Sex: Female, Male
    unit Of Measure
    Participants
  3. classes
    1. categories
      1. measurements
        1. group Id
          BG000
          value
          0
        2. group Id
          BG001
          value
          0
        3. group Id
          BG002
          value
          0
        4. group Id
          BG003
          value
          0
        5. group Id
          BG004
          value
          0
        6. group Id
          BG005
          value
          0
        7. group Id
          BG006
          value
          0
        8. group Id
          BG007
          value
          0
        9. group Id
          BG008
          value
          0
        10. group Id
          BG009
          value
          0
        11. group Id
          BG010
          value
          0
        12. group Id
          BG011
          value
          11846
      title
      0-1 years
    2. categories
      1. measurements
        1. group Id
          BG000
          value
          12001
        2. group Id
          BG001
          value
          99830
        3. group Id
          BG002
          value
          115
        4. group Id
          BG003
          value
          866
        5. group Id
          BG004
          value
          14
        6. group Id
          BG005
          value
          135
        7. group Id
          BG006
          value
          644
        8. group Id
          BG007
          value
          5014
        9. group Id
          BG008
          value
          35
        10. group Id
          BG009
          value
          331
        11. group Id
          BG010
          value
          1361
        12. group Id
          BG011
          value
          11846
      title
      2-3 years
    3. categories
      1. measurements
        1. group Id
          BG000
          value
          12675
        2. group Id
          BG001
          value
          108112
        3. group Id
          BG002
          value
          123
        4. group Id
          BG003
          value
          1048
        5. group Id
          BG004
          value
          20
        6. group Id
          BG005
          value
          164
        7. group Id
          BG006
          value
          708
        8. group Id
          BG007
          value
          5868
        9. group Id
          BG008
          value
          35
        10. group Id
          BG009
          value
          308
        11. group Id
          BG010
          value
          1426
        12. group Id
          BG011
          value
          12724
      title
      4-5 years
    4. categories
      1. measurements
        1. group Id
          BG000
          value
          13403
        2. group Id
          BG001
          value
          119691
        3. group Id
          BG002
          value
          157
        4. group Id
          BG003
          value
          1321
        5. group Id
          BG004
          value
          13
        6. group Id
          BG005
          value
          121
        7. group Id
          BG006
          value
          802
        8. group Id
          BG007
          value
          6978
        9. group Id
          BG008
          value
          29
        10. group Id
          BG009
          value
          264
        11. group Id
          BG010
          value
          1508
        12. group Id
          BG011
          value
          14037
      title
      6-7 years
    5. categories
      1. measurements
        1. group Id
          BG000
          value
          141059
        2. group Id
          BG001
          value
          1383317
        3. group Id
          BG002
          value
          1482
        4. group Id
          BG003
          value
          14618
        5. group Id
          BG004
          value
          165
        6. group Id
          BG005
          value
          1647
        7. group Id
          BG006
          value
          8681
        8. group Id
          BG007
          value
          84976
        9. group Id
          BG008
          value
          201
        10. group Id
          BG009
          value
          2032
        11. group Id
          BG010
          value
          15269
        12. group Id
          BG011
          value
          150317
      title
      8+ years
    description
    Entry into the GPRD study cohort began January 1, 1993, or at the time of GPRD registration if after January 1, 1993. Participants were required to have at least 2 years of follow-up prior to the index date.
    param Type
    NUMBER
    title
    Number of participants with the indicated duration of follow-up from registration to index date
    unit Of Measure
    participants
  4. classes
    1. categories
      1. measurements
        1. group Id
          BG000
          value
          0
        2. group Id
          BG001
          value
          0
        3. group Id
          BG002
          value
          0
        4. group Id
          BG003
          value
          3216
        5. group Id
          BG004
          value
          0
        6. group Id
          BG005
          value
          0
        7. group Id
          BG006
          value
          0
        8. group Id
          BG007
          value
          0
        9. group Id
          BG008
          value
          0
        10. group Id
          BG009
          value
          0
        11. group Id
          BG010
          value
          0
        12. group Id
          BG011
          value
          0
      title
      0-1 years
    2. categories
      1. measurements
        1. group Id
          BG000
          value
          24693
        2. group Id
          BG001
          value
          226195
        3. group Id
          BG002
          value
          351
        4. group Id
          BG003
          value
          3216
        5. group Id
          BG004
          value
          32
        6. group Id
          BG005
          value
          319
        7. group Id
          BG006
          value
          1627
        8. group Id
          BG007
          value
          14736
        9. group Id
          BG008
          value
          48
        10. group Id
          BG009
          value
          458
        11. group Id
          BG010
          value
          2784
        12. group Id
          BG011
          value
          26004
      title
      2-3 years
    3. categories
      1. measurements
        1. group Id
          BG000
          value
          24123
        2. group Id
          BG001
          value
          223084
        3. group Id
          BG002
          value
          281
        4. group Id
          BG003
          value
          2628
        5. group Id
          BG004
          value
          32
        6. group Id
          BG005
          value
          288
        7. group Id
          BG006
          value
          1489
        8. group Id
          BG007
          value
          13563
        9. group Id
          BG008
          value
          48
        10. group Id
          BG009
          value
          451
        11. group Id
          BG010
          value
          2718
        12. group Id
          BG011
          value
          25616
      title
      4-5 years
    4. categories
      1. measurements
        1. group Id
          BG000
          value
          25608
        2. group Id
          BG001
          value
          241586
        3. group Id
          BG002
          value
          231
        4. group Id
          BG003
          value
          2108
        5. group Id
          BG004
          value
          26
        6. group Id
          BG005
          value
          257
        7. group Id
          BG006
          value
          1577
        8. group Id
          BG007
          value
          14855
        9. group Id
          BG008
          value
          49
        10. group Id
          BG009
          value
          490
        11. group Id
          BG010
          value
          2830
        12. group Id
          BG011
          value
          27109
      title
      6-7 years
    5. categories
      1. measurements
        1. group Id
          BG000
          value
          104714
        2. group Id
          BG001
          value
          1020085
        3. group Id
          BG002
          value
          1014
        4. group Id
          BG003
          value
          9901
        5. group Id
          BG004
          value
          122
        6. group Id
          BG005
          value
          1203
        7. group Id
          BG006
          value
          6162
        8. group Id
          BG007
          value
          59682
        9. group Id
          BG008
          value
          155
        10. group Id
          BG009
          value
          1536
        11. group Id
          BG010
          value
          11232
        12. group Id
          BG011
          value
          110195
      title
      8+ years
    description
    Entry into the GPRD study cohort began January 1, 1993, or at the time of GPRD registration if after January 1, 1993. Participants were required to have at least 2 years of follow-up prior to the index date.
    param Type
    NUMBER
    title
    Number of participants with the indicated duration of follow-up from cohort entry to index date
    unit Of Measure
    participants
  5. classes
    1. categories
      1. measurements
        1. group Id
          BG000
          value
          2393
        2. group Id
          BG001
          value
          19861
        3. group Id
          BG002
          value
          30
        4. group Id
          BG003
          value
          190
        5. group Id
          BG004
          value
          5
        6. group Id
          BG005
          value
          30
        7. group Id
          BG006
          value
          255
        8. group Id
          BG007
          value
          1081
        9. group Id
          BG008
          value
          7
        10. group Id
          BG009
          value
          38
        11. group Id
          BG010
          value
          267
        12. group Id
          BG011
          value
          3059
      title
      BMI: < 18.5 kg/m^2
    2. categories
      1. measurements
        1. group Id
          BG000
          value
          61913
        2. group Id
          BG001
          value
          569726
        3. group Id
          BG002
          value
          580
        4. group Id
          BG003
          value
          5429
        5. group Id
          BG004
          value
          82
        6. group Id
          BG005
          value
          674
        7. group Id
          BG006
          value
          3912
        8. group Id
          BG007
          value
          31787
        9. group Id
          BG008
          value
          72
        10. group Id
          BG009
          value
          741
        11. group Id
          BG010
          value
          7813
        12. group Id
          BG011
          value
          75516
      title
      BMI: 18.5 to 24.99 kg/m^2
    3. categories
      1. measurements
        1. group Id
          BG000
          value
          54471
        2. group Id
          BG001
          value
          508109
        3. group Id
          BG002
          value
          579
        4. group Id
          BG003
          value
          5483
        5. group Id
          BG004
          value
          55
        6. group Id
          BG005
          value
          581
        7. group Id
          BG006
          value
          3070
        8. group Id
          BG007
          value
          33035
        9. group Id
          BG008
          value
          70
        10. group Id
          BG009
          value
          580
        11. group Id
          BG010
          value
          5054
        12. group Id
          BG011
          value
          47989
      title
      BMI: 25 to 29.99 kg/m^2
    4. categories
      1. measurements
        1. group Id
          BG000
          value
          22152
        2. group Id
          BG001
          value
          206232
        3. group Id
          BG002
          value
          245
        4. group Id
          BG003
          value
          2001
        5. group Id
          BG004
          value
          21
        6. group Id
          BG005
          value
          254
        7. group Id
          BG006
          value
          1097
        8. group Id
          BG007
          value
          12814
        9. group Id
          BG008
          value
          25
        10. group Id
          BG009
          value
          285
        11. group Id
          BG010
          value
          2773
        12. group Id
          BG011
          value
          25819
      title
      BMI: 30 kg/m^2 or greater
    5. categories
      1. measurements
        1. group Id
          BG000
          value
          38209
        2. group Id
          BG001
          value
          407022
        3. group Id
          BG002
          value
          443
        4. group Id
          BG003
          value
          4750
        5. group Id
          BG004
          value
          49
        6. group Id
          BG005
          value
          528
        7. group Id
          BG006
          value
          2521
        8. group Id
          BG007
          value
          24119
        9. group Id
          BG008
          value
          126
        10. group Id
          BG009
          value
          1291
        11. group Id
          BG010
          value
          3657
        12. group Id
          BG011
          value
          36541
      title
      BMI: Missing
    description
    BMI is calculated as weight in kilograms (kg) (closest to cohort entry date, up to one year prior to index date) divided by height in meters squared (m\^2) (one year or longer prior to index date).
    param Type
    NUMBER
    title
    Number of participants with the indicated Body Mass Index (BMI)
    unit Of Measure
    participants
  6. classes
    1. categories
      1. measurements
        1. group Id
          BG000
          value
          38033
        2. group Id
          BG001
          value
          306184
        3. group Id
          BG002
          value
          375
        4. group Id
          BG003
          value
          2902
        5. group Id
          BG004
          value
          63
        6. group Id
          BG005
          value
          379
        7. group Id
          BG006
          value
          4806
        8. group Id
          BG007
          value
          18856
        9. group Id
          BG008
          value
          51
        10. group Id
          BG009
          value
          476
        11. group Id
          BG010
          value
          3572
        12. group Id
          BG011
          value
          34818
      title
      Current Smoker
    2. categories
      1. measurements
        1. group Id
          BG000
          value
          41270
        2. group Id
          BG001
          value
          354651
        3. group Id
          BG002
          value
          531
        4. group Id
          BG003
          value
          4134
        5. group Id
          BG004
          value
          41
        6. group Id
          BG005
          value
          380
        7. group Id
          BG006
          value
          3594
        8. group Id
          BG007
          value
          24290
        9. group Id
          BG008
          value
          43
        10. group Id
          BG009
          value
          385
        11. group Id
          BG010
          value
          3156
        12. group Id
          BG011
          value
          28210
      title
      Ex-Smoker
    3. categories
      1. measurements
        1. group Id
          BG000
          value
          85483
        2. group Id
          BG001
          value
          854263
        3. group Id
          BG002
          value
          810
        4. group Id
          BG003
          value
          8540
        5. group Id
          BG004
          value
          83
        6. group Id
          BG005
          value
          1048
        7. group Id
          BG006
          value
          1766
        8. group Id
          BG007
          value
          48127
        9. group Id
          BG008
          value
          133
        10. group Id
          BG009
          value
          1255
        11. group Id
          BG010
          value
          11396
        12. group Id
          BG011
          value
          109463
      title
      Never Smoked
    4. categories
      1. measurements
        1. group Id
          BG000
          value
          14352
        2. group Id
          BG001
          value
          195852
        3. group Id
          BG002
          value
          161
        4. group Id
          BG003
          value
          2277
        5. group Id
          BG004
          value
          25
        6. group Id
          BG005
          value
          260
        7. group Id
          BG006
          value
          689
        8. group Id
          BG007
          value
          11563
        9. group Id
          BG008
          value
          73
        10. group Id
          BG009
          value
          819
        11. group Id
          BG010
          value
          1440
        12. group Id
          BG011
          value
          16433
      title
      Unknown
    param Type
    NUMBER
    title
    Number of participants with the indicated smoking status
    unit Of Measure
    participants
  7. classes
    1. categories
      1. measurements
        1. group Id
          BG000
          value
          36134
        2. group Id
          BG001
          value
          340399
        3. group Id
          BG002
          value
          422
        4. group Id
          BG003
          value
          3817
        5. group Id
          BG004
          value
          0
        6. group Id
          BG005
          value
          0
        7. group Id
          BG006
          value
          2412
        8. group Id
          BG007
          value
          21471
        9. group Id
          BG008
          value
          0
        10. group Id
          BG009
          value
          0
        11. group Id
          BG010
          value
          4585
        12. group Id
          BG011
          value
          44823
      title
      0 units/day
    2. categories
      1. measurements
        1. group Id
          BG000
          value
          86422
        2. group Id
          BG001
          value
          801383
        3. group Id
          BG002
          value
          839
        4. group Id
          BG003
          value
          7659
        5. group Id
          BG004
          value
          0
        6. group Id
          BG005
          value
          0
        7. group Id
          BG006
          value
          4661
        8. group Id
          BG007
          value
          46769
        9. group Id
          BG008
          value
          0
        10. group Id
          BG009
          value
          0
        11. group Id
          BG010
          value
          9947
        12. group Id
          BG011
          value
          93964
      title
      1-2 units/day
    3. categories
      1. measurements
        1. group Id
          BG000
          value
          11929
        2. group Id
          BG001
          value
          102201
        3. group Id
          BG002
          value
          115
        4. group Id
          BG003
          value
          1118
        5. group Id
          BG004
          value
          0
        6. group Id
          BG005
          value
          0
        7. group Id
          BG006
          value
          868
        8. group Id
          BG007
          value
          6843
        9. group Id
          BG008
          value
          0
        10. group Id
          BG009
          value
          0
        11. group Id
          BG010
          value
          535
        12. group Id
          BG011
          value
          4544
      title
      3-6 units/day
    4. categories
      1. measurements
        1. group Id
          BG000
          value
          1992
        2. group Id
          BG001
          value
          15014
        3. group Id
          BG002
          value
          18
        4. group Id
          BG003
          value
          157
        5. group Id
          BG004
          value
          0
        6. group Id
          BG005
          value
          0
        7. group Id
          BG006
          value
          202
        8. group Id
          BG007
          value
          1132
        9. group Id
          BG008
          value
          0
        10. group Id
          BG009
          value
          0
        11. group Id
          BG010
          value
          50
        12. group Id
          BG011
          value
          399
      title
      7+ units/day
    5. categories
      1. measurements
        1. group Id
          BG000
          value
          42661
        2. group Id
          BG001
          value
          451953
        3. group Id
          BG002
          value
          483
        4. group Id
          BG003
          value
          5102
        5. group Id
          BG004
          value
          0
        6. group Id
          BG005
          value
          0
        7. group Id
          BG006
          value
          2712
        8. group Id
          BG007
          value
          26621
        9. group Id
          BG008
          value
          0
        10. group Id
          BG009
          value
          0
        11. group Id
          BG010
          value
          4447
        12. group Id
          BG011
          value
          45194
      title
      Missing
    description
    One unit of alcohol was defined as the equivalent of 10 milliliters (ml) of ethyl alcohol. A zero (0) has been entered for the cases and controls of the following cancers because data were not collected in participants: anal, bone/joint, penile, bladder, other nervous system, pancreatic, and renal.
    param Type
    NUMBER
    title
    Number of participants with the indicated alcohol consumption (per day)
    unit Of Measure
    participants
  8. classes
    1. categories
      1. measurements
        1. group Id
          BG000
          value
          0
        2. group Id
          BG001
          value
          0
        3. group Id
          BG002
          value
          796
        4. group Id
          BG003
          value
          5202
        5. group Id
          BG004
          value
          0
        6. group Id
          BG005
          value
          0
        7. group Id
          BG006
          value
          0
        8. group Id
          BG007
          value
          0
        9. group Id
          BG008
          value
          0
        10. group Id
          BG009
          value
          0
        11. group Id
          BG010
          value
          0
        12. group Id
          BG011
          value
          0
      title
      Acid suppressing drugs (>6 mo. before index date)
    2. categories
      1. measurements
        1. group Id
          BG000
          value
          87337
        2. group Id
          BG001
          value
          765861
        3. group Id
          BG002
          value
          924
        4. group Id
          BG003
          value
          7779
        5. group Id
          BG004
          value
          92
        6. group Id
          BG005
          value
          924
        7. group Id
          BG006
          value
          5626
        8. group Id
          BG007
          value
          46417
        9. group Id
          BG008
          value
          130
        10. group Id
          BG009
          value
          1008
        11. group Id
          BG010
          value
          9603
        12. group Id
          BG011
          value
          91302
      title
      Back pain
    3. categories
      1. measurements
        1. group Id
          BG000
          value
          0
        2. group Id
          BG001
          value
          0
        3. group Id
          BG002
          value
          0
        4. group Id
          BG003
          value
          0
        5. group Id
          BG004
          value
          0
        6. group Id
          BG005
          value
          0
        7. group Id
          BG006
          value
          0
        8. group Id
          BG007
          value
          0
        9. group Id
          BG008
          value
          0
        10. group Id
          BG009
          value
          0
        11. group Id
          BG010
          value
          894
        12. group Id
          BG011
          value
          5508
      title
      Benign breast disease
    4. categories
      1. measurements
        1. group Id
          BG000
          value
          0
        2. group Id
          BG001
          value
          0
        3. group Id
          BG002
          value
          0
        4. group Id
          BG003
          value
          0
        5. group Id
          BG004
          value
          0
        6. group Id
          BG005
          value
          0
        7. group Id
          BG006
          value
          2532
        8. group Id
          BG007
          value
          6639
        9. group Id
          BG008
          value
          0
        10. group Id
          BG009
          value
          0
        11. group Id
          BG010
          value
          0
        12. group Id
          BG011
          value
          0
      title
      Chronic obstructive pulmonary disease (COPD)
    5. categories
      1. measurements
        1. group Id
          BG000
          value
          0
        2. group Id
          BG001
          value
          0
        3. group Id
          BG002
          value
          0
        4. group Id
          BG003
          value
          0
        5. group Id
          BG004
          value
          0
        6. group Id
          BG005
          value
          0
        7. group Id
          BG006
          value
          0
        8. group Id
          BG007
          value
          0
        9. group Id
          BG008
          value
          0
        10. group Id
          BG009
          value
          0
        11. group Id
          BG010
          value
          0
        12. group Id
          BG011
          value
          0
      title
      Chronic pancreatitis
    6. categories
      1. measurements
        1. group Id
          BG000
          value
          0
        2. group Id
          BG001
          value
          0
        3. group Id
          BG002
          value
          0
        4. group Id
          BG003
          value
          0
        5. group Id
          BG004
          value
          0
        6. group Id
          BG005
          value
          0
        7. group Id
          BG006
          value
          0
        8. group Id
          BG007
          value
          0
        9. group Id
          BG008
          value
          0
        10. group Id
          BG009
          value
          0
        11. group Id
          BG010
          value
          2916
        12. group Id
          BG011
          value
          22576
      title
      Current estrogen (within 6 months of index date)
    7. categories
      1. measurements
        1. group Id
          BG000
          value
          15280
        2. group Id
          BG001
          value
          130210
        3. group Id
          BG002
          value
          208
        4. group Id
          BG003
          value
          1592
        5. group Id
          BG004
          value
          17
        6. group Id
          BG005
          value
          139
        7. group Id
          BG006
          value
          1086
        8. group Id
          BG007
          value
          9448
        9. group Id
          BG008
          value
          15
        10. group Id
          BG009
          value
          155
        11. group Id
          BG010
          value
          1162
        12. group Id
          BG011
          value
          9899
      title
      Diabetes
    8. categories
      1. measurements
        1. group Id
          BG000
          value
          0
        2. group Id
          BG001
          value
          0
        3. group Id
          BG002
          value
          0
        4. group Id
          BG003
          value
          0
        5. group Id
          BG004
          value
          0
        6. group Id
          BG005
          value
          0
        7. group Id
          BG006
          value
          0
        8. group Id
          BG007
          value
          0
        9. group Id
          BG008
          value
          0
        10. group Id
          BG009
          value
          0
        11. group Id
          BG010
          value
          0
        12. group Id
          BG011
          value
          0
      title
      Diuretic use (at any time up to the index date)
    9. categories
      1. measurements
        1. group Id
          BG000
          value
          3015
        2. group Id
          BG001
          value
          24226
        3. group Id
          BG002
          value
          32
        4. group Id
          BG003
          value
          271
        5. group Id
          BG004
          value
          8
        6. group Id
          BG005
          value
          23
        7. group Id
          BG006
          value
          214
        8. group Id
          BG007
          value
          1577
        9. group Id
          BG008
          value
          3
        10. group Id
          BG009
          value
          33
        11. group Id
          BG010
          value
          285
        12. group Id
          BG011
          value
          2486
      title
      Epilepsy
    10. categories
      1. measurements
        1. group Id
          BG000
          value
          0
        2. group Id
          BG001
          value
          0
        3. group Id
          BG002
          value
          0
        4. group Id
          BG003
          value
          0
        5. group Id
          BG004
          value
          3
        6. group Id
          BG005
          value
          0
        7. group Id
          BG006
          value
          0
        8. group Id
          BG007
          value
          0
        9. group Id
          BG008
          value
          0
        10. group Id
          BG009
          value
          0
        11. group Id
          BG010
          value
          0
        12. group Id
          BG011
          value
          0
      title
      Human immunodeficiency virus (HIV)
    11. categories
      1. measurements
        1. group Id
          BG000
          value
          0
        2. group Id
          BG001
          value
          0
        3. group Id
          BG002
          value
          0
        4. group Id
          BG003
          value
          0
        5. group Id
          BG004
          value
          15
        6. group Id
          BG005
          value
          7
        7. group Id
          BG006
          value
          0
        8. group Id
          BG007
          value
          0
        9. group Id
          BG008
          value
          0
        10. group Id
          BG009
          value
          0
        11. group Id
          BG010
          value
          0
        12. group Id
          BG011
          value
          0
      title
      Human papillomavirus (HPV) (genital)
    12. categories
      1. measurements
        1. group Id
          BG000
          value
          0
        2. group Id
          BG001
          value
          0
        3. group Id
          BG002
          value
          0
        4. group Id
          BG003
          value
          0
        5. group Id
          BG004
          value
          0
        6. group Id
          BG005
          value
          0
        7. group Id
          BG006
          value
          0
        8. group Id
          BG007
          value
          0
        9. group Id
          BG008
          value
          0
        10. group Id
          BG009
          value
          0
        11. group Id
          BG010
          value
          0
        12. group Id
          BG011
          value
          0
      title
      Hypertension
    description
    Medication use was defined by British National Formulary codes for the medications. Comorbid conditions were defined by READ/OXMIS codes at any time up to the index date, except for diabetes, which was assessed up to 2 years prior to index date for the pancreatic cancer analysis. A zero (0) indicates that data were not collected for the respective comorbidity, except for the following: HIV (Anal Cancer Controls, Penile Cancer Cases \& Controls,) and Epilepsy (Penile Cancer Cases). mo., months.
    param Type
    NUMBER
    title
    Number of participants using indicated class of medications or having the indicated comorbidities
    unit Of Measure
    participants
Complete source fields
denoms
  1. counts
    1. group Id
      BG000
      value
      179138
    2. group Id
      BG001
      value
      1710950
    3. group Id
      BG002
      value
      1877
    4. group Id
      BG003
      value
      17853
    5. group Id
      BG004
      value
      212
    6. group Id
      BG005
      value
      2067
    7. group Id
      BG006
      value
      10855
    8. group Id
      BG007
      value
      102836
    9. group Id
      BG008
      value
      300
    10. group Id
      BG009
      value
      2935
    11. group Id
      BG010
      value
      19564
    12. group Id
      BG011
      value
      188924
    units
    Participants
groups
  1. description
    Incidence of all cancers defined as first time incident cancer diagnosis (READ/Oxford Medical Information System \[OXMIS\] codes) in the General Practice Research Database (GPRD) study cohort. Entry into the study cohort began January 1, 1993, or at the time of GPRD registration if after January 1, 1993. Follow-up ended December 31, 2008, or earlier if the respective cancer was diagnosed or if the participant left the GPRD for any reason including death. Participants with a prior history of cancer were excluded.
    id
    BG000
    title
    All-Cancer: Cases
  2. description
    Cancer cases were risk set matched with up to 10 controls for sex, age at GPRD study cohort entry (within two years), calendar year of cohort entry (within one year), and General Practice site. The index date for controls was set as the date at which the follow-up time from cohort entry was the same as the case. The index date was chosen so as to give the control equal follow-up time to that of the case for ascertainment of use of gabapentin. Participants with a history of cancer prior to the index date were excluded as controls.
    id
    BG001
    title
    All-Cancer: Controls
  3. description
    Incidence of stomach cancer defined as first time incident cancer diagnosis (READ/Oxford Medical Information System \[OXMIS\] codes) in the General Practice Research Database (GPRD) study cohort. Entry into the study cohort began January 1, 1993, or at the time of GPRD registration if after January 1, 1993. Follow-up ended December 31, 2008, or earlier if the respective cancer was diagnosed or if the participant left the GPRD for any reason including death. Participants with a prior history of cancer were excluded.
    id
    BG002
    title
    Stomach Cancer: Cases
  4. description
    Cancer cases were risk set matched with up to 10 controls for sex, age at GPRD study cohort entry (within two years), calendar year of cohort entry (within one year), and General Practice site. The index date for controls was set as the date at which the follow-up time from cohort entry was the same as the case. The index date was chosen so as to give the control equal follow-up time to that of the case for ascertainment of use of gabapentin. Participants with a history of cancer prior to the index date were excluded as controls.
    id
    BG003
    title
    Stomach Cancer: Controls
  5. description
    Incidence of anal cancer defined as first time incident cancer diagnosis (READ/Oxford Medical Information System \[OXMIS\] codes) in the General Practice Research Database (GPRD) study cohort. Entry into the study cohort began January 1, 1993, or at the time of GPRD registration if after January 1, 1993. Follow-up ended December 31, 2008, or earlier if the respective cancer was diagnosed or if the participant left the GPRD for any reason including death. Participants with a prior history of cancer were excluded.
    id
    BG004
    title
    Anal Cancer: Cases
  6. description
    Cancer cases were risk set matched with up to 10 controls for sex, age at GPRD study cohort entry (within two years), calendar year of cohort entry (within one year), and General Practice site. The index date for controls was set as the date at which the follow-up time from cohort entry was the same as the case. The index date was chosen so as to give the control equal follow-up time to that of the case for ascertainment of use of gabapentin. Participants with a history of cancer prior to the index date were excluded as controls.
    id
    BG005
    title
    Anal Cancer: Controls
  7. description
    Incidence of lung cancer defined as first time incident cancer diagnosis (READ/Oxford Medical Information System \[OXMIS\] codes) in the General Practice Research Database (GPRD) study cohort. Entry into the study cohort began January 1, 1993, or at the time of GPRD registration if after January 1, 1993. Follow-up ended December 31, 2008, or earlier if the respective cancer was diagnosed or if the participant left the GPRD for any reason including death. Participants with a prior history of cancer were excluded.
    id
    BG006
    title
    Lung Cancer: Cases
  8. description
    Cancer cases were risk set matched with up to 10 controls for sex, age at GPRD study cohort entry (within two years), calendar year of cohort entry (within one year), and General Practice site. The index date for controls was set as the date at which the follow-up time from cohort entry was the same as the case. The index date was chosen so as to give the control equal follow-up time to that of the case for ascertainment of use of gabapentin. Participants with a history of cancer prior to the index date were excluded as controls.
    id
    BG007
    title
    Lung Cancer: Controls
  9. description
    Incidence of bone/joint cancer defined as first time incident cancer diagnosis (READ/Oxford Medical Information System \[OXMIS\] codes) in the General Practice Research Database (GPRD) study cohort. Entry into the study cohort began January 1, 1993, or at the time of GPRD registration if after January 1, 1993. Follow-up ended December 31, 2008, or earlier if the respective cancer was diagnosed or if the participant left the GPRD for any reason including death. Participants with a prior history of cancer were excluded.
    id
    BG008
    title
    Bone/Joint Cancer: Cases
  10. description
    Cancer cases were risk set matched with up to 10 controls for sex, age at GPRD study cohort entry (within two years), calendar year of cohort entry (within one year), and General Practice site. The index date for controls was set as the date at which the follow-up time from cohort entry was the same as the case. The index date was chosen so as to give the control equal follow-up time to that of the case for ascertainment of use of gabapentin. Participants with a history of cancer prior to the index date were excluded as controls.
    id
    BG009
    title
    Bone/Joint Cancer: Controls
  11. description
    Incidence of breast cancer defined as first time incident cancer diagnosis (READ/Oxford Medical Information System \[OXMIS\] codes) in the General Practice Research Database (GPRD) study cohort. Entry into the study cohort began January 1, 1993, or at the time of GPRD registration if after January 1, 1993. Follow-up ended December 31, 2008, or earlier if the respective cancer was diagnosed or if the participant left the GPRD for any reason including death. Participants with a prior history of cancer were excluded.
    id
    BG010
    title
    Breast Cancer: Cases
  12. description
    Cancer cases were risk set matched with up to 10 controls for sex, age at GPRD study cohort entry (within two years), calendar year of cohort entry (within one year), and General Practice site. The index date for controls was set as the date at which the follow-up time from cohort entry was the same as the case. The index date was chosen so as to give the control equal follow-up time to that of the case for ascertainment of use of gabapentin. Participants with a history of cancer prior to the index date were excluded as controls.
    id
    BG011
    title
    Breast Cancer: Controls
measures
  1. classes
    1. categories
      1. measurements
        1. group Id
          BG000
          value
          10246
        2. group Id
          BG001
          value
          101968
        3. group Id
          BG002
          value
          16
        4. group Id
          BG003
          value
          155
        5. group Id
          BG004
          value
          12
        6. group Id
          BG005
          value
          118
        7. group Id
          BG006
          value
          36
        8. group Id
          BG007
          value
          369
        9. group Id
          BG008
          value
          120
        10. group Id
          BG009
          value
          1173
        11. group Id
          BG010
          value
          915
        12. group Id
          BG011
          value
          9346
      title
      < 40 years
    2. categories
      1. measurements
        1. group Id
          BG000
          value
          13112
        2. group Id
          BG001
          value
          132244
        3. group Id
          BG002
          value
          48
        4. group Id
          BG003
          value
          469
        5. group Id
          BG004
          value
          18
        6. group Id
          BG005
          value
          200
        7. group Id
          BG006
          value
          294
        8. group Id
          BG007
          value
          2973
        9. group Id
          BG008
          value
          21
        10. group Id
          BG009
          value
          254
        11. group Id
          BG010
          value
          2827
        12. group Id
          BG011
          value
          29167
      title
      40-49 years
    3. categories
      1. measurements
        1. group Id
          BG000
          value
          28392
        2. group Id
          BG001
          value
          279797
        3. group Id
          BG002
          value
          135
        4. group Id
          BG003
          value
          1388
        5. group Id
          BG004
          value
          47
        6. group Id
          BG005
          value
          467
        7. group Id
          BG006
          value
          1256
        8. group Id
          BG007
          value
          12388
        9. group Id
          BG008
          value
          46
        10. group Id
          BG009
          value
          422
        11. group Id
          BG010
          value
          5319
        12. group Id
          BG011
          value
          51266
      title
      50-59 years
    4. categories
      1. measurements
        1. group Id
          BG000
          value
          43077
        2. group Id
          BG001
          value
          415567
        3. group Id
          BG002
          value
          395
        4. group Id
          BG003
          value
          3850
        5. group Id
          BG004
          value
          45
        6. group Id
          BG005
          value
          464
        7. group Id
          BG006
          value
          2944
        8. group Id
          BG007
          value
          28526
        9. group Id
          BG008
          value
          38
        10. group Id
          BG009
          value
          360
        11. group Id
          BG010
          value
          4665
        12. group Id
          BG011
          value
          44769
      title
      60-69 years
    5. categories
      1. measurements
        1. group Id
          BG000
          value
          50072
        2. group Id
          BG001
          value
          475887
        3. group Id
          BG002
          value
          679
        4. group Id
          BG003
          value
          6559
        5. group Id
          BG004
          value
          50
        6. group Id
          BG005
          value
          440
        7. group Id
          BG006
          value
          4092
        8. group Id
          BG007
          value
          38557
        9. group Id
          BG008
          value
          51
        10. group Id
          BG009
          value
          501
        11. group Id
          BG010
          value
          3334
        12. group Id
          BG011
          value
          32051
      title
      70-79 years
    6. categories
      1. measurements
        1. group Id
          BG000
          value
          34239
        2. group Id
          BG001
          value
          305487
        3. group Id
          BG002
          value
          604
        4. group Id
          BG003
          value
          5432
        5. group Id
          BG004
          value
          40
        6. group Id
          BG005
          value
          378
        7. group Id
          BG006
          value
          2233
        8. group Id
          BG007
          value
          20023
        9. group Id
          BG008
          value
          24
        10. group Id
          BG009
          value
          225
        11. group Id
          BG010
          value
          2504
        12. group Id
          BG011
          value
          22325
      title
      80+ years
    param Type
    NUMBER
    title
    Age, Customized
    unit Of Measure
    participants
  2. classes
    1. categories
      1. measurements
        1. group Id
          BG000
          value
          92099
        2. group Id
          BG001
          value
          883331
        3. group Id
          BG002
          value
          716
        4. group Id
          BG003
          value
          6789
        5. group Id
          BG004
          value
          133
        6. group Id
          BG005
          value
          1294
        7. group Id
          BG006
          value
          4259
        8. group Id
          BG007
          value
          40345
        9. group Id
          BG008
          value
          156
        10. group Id
          BG009
          value
          1538
        11. group Id
          BG010
          value
          19564
        12. group Id
          BG011
          value
          188924
        title
        Female
      2. measurements
        1. group Id
          BG000
          value
          87039
        2. group Id
          BG001
          value
          827619
        3. group Id
          BG002
          value
          1161
        4. group Id
          BG003
          value
          11064
        5. group Id
          BG004
          value
          79
        6. group Id
          BG005
          value
          773
        7. group Id
          BG006
          value
          6596
        8. group Id
          BG007
          value
          62491
        9. group Id
          BG008
          value
          144
        10. group Id
          BG009
          value
          1397
        11. group Id
          BG010
          value
          0
        12. group Id
          BG011
          value
          0
        title
        Male
    param Type
    COUNT_OF_PARTICIPANTS
    title
    Sex: Female, Male
    unit Of Measure
    Participants
  3. classes
    1. categories
      1. measurements
        1. group Id
          BG000
          value
          0
        2. group Id
          BG001
          value
          0
        3. group Id
          BG002
          value
          0
        4. group Id
          BG003
          value
          0
        5. group Id
          BG004
          value
          0
        6. group Id
          BG005
          value
          0
        7. group Id
          BG006
          value
          0
        8. group Id
          BG007
          value
          0
        9. group Id
          BG008
          value
          0
        10. group Id
          BG009
          value
          0
        11. group Id
          BG010
          value
          0
        12. group Id
          BG011
          value
          11846
      title
      0-1 years
    2. categories
      1. measurements
        1. group Id
          BG000
          value
          12001
        2. group Id
          BG001
          value
          99830
        3. group Id
          BG002
          value
          115
        4. group Id
          BG003
          value
          866
        5. group Id
          BG004
          value
          14
        6. group Id
          BG005
          value
          135
        7. group Id
          BG006
          value
          644
        8. group Id
          BG007
          value
          5014
        9. group Id
          BG008
          value
          35
        10. group Id
          BG009
          value
          331
        11. group Id
          BG010
          value
          1361
        12. group Id
          BG011
          value
          11846
      title
      2-3 years
    3. categories
      1. measurements
        1. group Id
          BG000
          value
          12675
        2. group Id
          BG001
          value
          108112
        3. group Id
          BG002
          value
          123
        4. group Id
          BG003
          value
          1048
        5. group Id
          BG004
          value
          20
        6. group Id
          BG005
          value
          164
        7. group Id
          BG006
          value
          708
        8. group Id
          BG007
          value
          5868
        9. group Id
          BG008
          value
          35
        10. group Id
          BG009
          value
          308
        11. group Id
          BG010
          value
          1426
        12. group Id
          BG011
          value
          12724
      title
      4-5 years
    4. categories
      1. measurements
        1. group Id
          BG000
          value
          13403
        2. group Id
          BG001
          value
          119691
        3. group Id
          BG002
          value
          157
        4. group Id
          BG003
          value
          1321
        5. group Id
          BG004
          value
          13
        6. group Id
          BG005
          value
          121
        7. group Id
          BG006
          value
          802
        8. group Id
          BG007
          value
          6978
        9. group Id
          BG008
          value
          29
        10. group Id
          BG009
          value
          264
        11. group Id
          BG010
          value
          1508
        12. group Id
          BG011
          value
          14037
      title
      6-7 years
    5. categories
      1. measurements
        1. group Id
          BG000
          value
          141059
        2. group Id
          BG001
          value
          1383317
        3. group Id
          BG002
          value
          1482
        4. group Id
          BG003
          value
          14618
        5. group Id
          BG004
          value
          165
        6. group Id
          BG005
          value
          1647
        7. group Id
          BG006
          value
          8681
        8. group Id
          BG007
          value
          84976
        9. group Id
          BG008
          value
          201
        10. group Id
          BG009
          value
          2032
        11. group Id
          BG010
          value
          15269
        12. group Id
          BG011
          value
          150317
      title
      8+ years
    description
    Entry into the GPRD study cohort began January 1, 1993, or at the time of GPRD registration if after January 1, 1993. Participants were required to have at least 2 years of follow-up prior to the index date.
    param Type
    NUMBER
    title
    Number of participants with the indicated duration of follow-up from registration to index date
    unit Of Measure
    participants
  4. classes
    1. categories
      1. measurements
        1. group Id
          BG000
          value
          0
        2. group Id
          BG001
          value
          0
        3. group Id
          BG002
          value
          0
        4. group Id
          BG003
          value
          3216
        5. group Id
          BG004
          value
          0
        6. group Id
          BG005
          value
          0
        7. group Id
          BG006
          value
          0
        8. group Id
          BG007
          value
          0
        9. group Id
          BG008
          value
          0
        10. group Id
          BG009
          value
          0
        11. group Id
          BG010
          value
          0
        12. group Id
          BG011
          value
          0
      title
      0-1 years
    2. categories
      1. measurements
        1. group Id
          BG000
          value
          24693
        2. group Id
          BG001
          value
          226195
        3. group Id
          BG002
          value
          351
        4. group Id
          BG003
          value
          3216
        5. group Id
          BG004
          value
          32
        6. group Id
          BG005
          value
          319
        7. group Id
          BG006
          value
          1627
        8. group Id
          BG007
          value
          14736
        9. group Id
          BG008
          value
          48
        10. group Id
          BG009
          value
          458
        11. group Id
          BG010
          value
          2784
        12. group Id
          BG011
          value
          26004
      title
      2-3 years
    3. categories
      1. measurements
        1. group Id
          BG000
          value
          24123
        2. group Id
          BG001
          value
          223084
        3. group Id
          BG002
          value
          281
        4. group Id
          BG003
          value
          2628
        5. group Id
          BG004
          value
          32
        6. group Id
          BG005
          value
          288
        7. group Id
          BG006
          value
          1489
        8. group Id
          BG007
          value
          13563
        9. group Id
          BG008
          value
          48
        10. group Id
          BG009
          value
          451
        11. group Id
          BG010
          value
          2718
        12. group Id
          BG011
          value
          25616
      title
      4-5 years
    4. categories
      1. measurements
        1. group Id
          BG000
          value
          25608
        2. group Id
          BG001
          value
          241586
        3. group Id
          BG002
          value
          231
        4. group Id
          BG003
          value
          2108
        5. group Id
          BG004
          value
          26
        6. group Id
          BG005
          value
          257
        7. group Id
          BG006
          value
          1577
        8. group Id
          BG007
          value
          14855
        9. group Id
          BG008
          value
          49
        10. group Id
          BG009
          value
          490
        11. group Id
          BG010
          value
          2830
        12. group Id
          BG011
          value
          27109
      title
      6-7 years
    5. categories
      1. measurements
        1. group Id
          BG000
          value
          104714
        2. group Id
          BG001
          value
          1020085
        3. group Id
          BG002
          value
          1014
        4. group Id
          BG003
          value
          9901
        5. group Id
          BG004
          value
          122
        6. group Id
          BG005
          value
          1203
        7. group Id
          BG006
          value
          6162
        8. group Id
          BG007
          value
          59682
        9. group Id
          BG008
          value
          155
        10. group Id
          BG009
          value
          1536
        11. group Id
          BG010
          value
          11232
        12. group Id
          BG011
          value
          110195
      title
      8+ years
    description
    Entry into the GPRD study cohort began January 1, 1993, or at the time of GPRD registration if after January 1, 1993. Participants were required to have at least 2 years of follow-up prior to the index date.
    param Type
    NUMBER
    title
    Number of participants with the indicated duration of follow-up from cohort entry to index date
    unit Of Measure
    participants
  5. classes
    1. categories
      1. measurements
        1. group Id
          BG000
          value
          2393
        2. group Id
          BG001
          value
          19861
        3. group Id
          BG002
          value
          30
        4. group Id
          BG003
          value
          190
        5. group Id
          BG004
          value
          5
        6. group Id
          BG005
          value
          30
        7. group Id
          BG006
          value
          255
        8. group Id
          BG007
          value
          1081
        9. group Id
          BG008
          value
          7
        10. group Id
          BG009
          value
          38
        11. group Id
          BG010
          value
          267
        12. group Id
          BG011
          value
          3059
      title
      BMI: < 18.5 kg/m^2
    2. categories
      1. measurements
        1. group Id
          BG000
          value
          61913
        2. group Id
          BG001
          value
          569726
        3. group Id
          BG002
          value
          580
        4. group Id
          BG003
          value
          5429
        5. group Id
          BG004
          value
          82
        6. group Id
          BG005
          value
          674
        7. group Id
          BG006
          value
          3912
        8. group Id
          BG007
          value
          31787
        9. group Id
          BG008
          value
          72
        10. group Id
          BG009
          value
          741
        11. group Id
          BG010
          value
          7813
        12. group Id
          BG011
          value
          75516
      title
      BMI: 18.5 to 24.99 kg/m^2
    3. categories
      1. measurements
        1. group Id
          BG000
          value
          54471
        2. group Id
          BG001
          value
          508109
        3. group Id
          BG002
          value
          579
        4. group Id
          BG003
          value
          5483
        5. group Id
          BG004
          value
          55
        6. group Id
          BG005
          value
          581
        7. group Id
          BG006
          value
          3070
        8. group Id
          BG007
          value
          33035
        9. group Id
          BG008
          value
          70
        10. group Id
          BG009
          value
          580
        11. group Id
          BG010
          value
          5054
        12. group Id
          BG011
          value
          47989
      title
      BMI: 25 to 29.99 kg/m^2
    4. categories
      1. measurements
        1. group Id
          BG000
          value
          22152
        2. group Id
          BG001
          value
          206232
        3. group Id
          BG002
          value
          245
        4. group Id
          BG003
          value
          2001
        5. group Id
          BG004
          value
          21
        6. group Id
          BG005
          value
          254
        7. group Id
          BG006
          value
          1097
        8. group Id
          BG007
          value
          12814
        9. group Id
          BG008
          value
          25
        10. group Id
          BG009
          value
          285
        11. group Id
          BG010
          value
          2773
        12. group Id
          BG011
          value
          25819
      title
      BMI: 30 kg/m^2 or greater
    5. categories
      1. measurements
        1. group Id
          BG000
          value
          38209
        2. group Id
          BG001
          value
          407022
        3. group Id
          BG002
          value
          443
        4. group Id
          BG003
          value
          4750
        5. group Id
          BG004
          value
          49
        6. group Id
          BG005
          value
          528
        7. group Id
          BG006
          value
          2521
        8. group Id
          BG007
          value
          24119
        9. group Id
          BG008
          value
          126
        10. group Id
          BG009
          value
          1291
        11. group Id
          BG010
          value
          3657
        12. group Id
          BG011
          value
          36541
      title
      BMI: Missing
    description
    BMI is calculated as weight in kilograms (kg) (closest to cohort entry date, up to one year prior to index date) divided by height in meters squared (m\^2) (one year or longer prior to index date).
    param Type
    NUMBER
    title
    Number of participants with the indicated Body Mass Index (BMI)
    unit Of Measure
    participants
  6. classes
    1. categories
      1. measurements
        1. group Id
          BG000
          value
          38033
        2. group Id
          BG001
          value
          306184
        3. group Id
          BG002
          value
          375
        4. group Id
          BG003
          value
          2902
        5. group Id
          BG004
          value
          63
        6. group Id
          BG005
          value
          379
        7. group Id
          BG006
          value
          4806
        8. group Id
          BG007
          value
          18856
        9. group Id
          BG008
          value
          51
        10. group Id
          BG009
          value
          476
        11. group Id
          BG010
          value
          3572
        12. group Id
          BG011
          value
          34818
      title
      Current Smoker
    2. categories
      1. measurements
        1. group Id
          BG000
          value
          41270
        2. group Id
          BG001
          value
          354651
        3. group Id
          BG002
          value
          531
        4. group Id
          BG003
          value
          4134
        5. group Id
          BG004
          value
          41
        6. group Id
          BG005
          value
          380
        7. group Id
          BG006
          value
          3594
        8. group Id
          BG007
          value
          24290
        9. group Id
          BG008
          value
          43
        10. group Id
          BG009
          value
          385
        11. group Id
          BG010
          value
          3156
        12. group Id
          BG011
          value
          28210
      title
      Ex-Smoker
    3. categories
      1. measurements
        1. group Id
          BG000
          value
          85483
        2. group Id
          BG001
          value
          854263
        3. group Id
          BG002
          value
          810
        4. group Id
          BG003
          value
          8540
        5. group Id
          BG004
          value
          83
        6. group Id
          BG005
          value
          1048
        7. group Id
          BG006
          value
          1766
        8. group Id
          BG007
          value
          48127
        9. group Id
          BG008
          value
          133
        10. group Id
          BG009
          value
          1255
        11. group Id
          BG010
          value
          11396
        12. group Id
          BG011
          value
          109463
      title
      Never Smoked
    4. categories
      1. measurements
        1. group Id
          BG000
          value
          14352
        2. group Id
          BG001
          value
          195852
        3. group Id
          BG002
          value
          161
        4. group Id
          BG003
          value
          2277
        5. group Id
          BG004
          value
          25
        6. group Id
          BG005
          value
          260
        7. group Id
          BG006
          value
          689
        8. group Id
          BG007
          value
          11563
        9. group Id
          BG008
          value
          73
        10. group Id
          BG009
          value
          819
        11. group Id
          BG010
          value
          1440
        12. group Id
          BG011
          value
          16433
      title
      Unknown
    param Type
    NUMBER
    title
    Number of participants with the indicated smoking status
    unit Of Measure
    participants
  7. classes
    1. categories
      1. measurements
        1. group Id
          BG000
          value
          36134
        2. group Id
          BG001
          value
          340399
        3. group Id
          BG002
          value
          422
        4. group Id
          BG003
          value
          3817
        5. group Id
          BG004
          value
          0
        6. group Id
          BG005
          value
          0
        7. group Id
          BG006
          value
          2412
        8. group Id
          BG007
          value
          21471
        9. group Id
          BG008
          value
          0
        10. group Id
          BG009
          value
          0
        11. group Id
          BG010
          value
          4585
        12. group Id
          BG011
          value
          44823
      title
      0 units/day
    2. categories
      1. measurements
        1. group Id
          BG000
          value
          86422
        2. group Id
          BG001
          value
          801383
        3. group Id
          BG002
          value
          839
        4. group Id
          BG003
          value
          7659
        5. group Id
          BG004
          value
          0
        6. group Id
          BG005
          value
          0
        7. group Id
          BG006
          value
          4661
        8. group Id
          BG007
          value
          46769
        9. group Id
          BG008
          value
          0
        10. group Id
          BG009
          value
          0
        11. group Id
          BG010
          value
          9947
        12. group Id
          BG011
          value
          93964
      title
      1-2 units/day
    3. categories
      1. measurements
        1. group Id
          BG000
          value
          11929
        2. group Id
          BG001
          value
          102201
        3. group Id
          BG002
          value
          115
        4. group Id
          BG003
          value
          1118
        5. group Id
          BG004
          value
          0
        6. group Id
          BG005
          value
          0
        7. group Id
          BG006
          value
          868
        8. group Id
          BG007
          value
          6843
        9. group Id
          BG008
          value
          0
        10. group Id
          BG009
          value
          0
        11. group Id
          BG010
          value
          535
        12. group Id
          BG011
          value
          4544
      title
      3-6 units/day
    4. categories
      1. measurements
        1. group Id
          BG000
          value
          1992
        2. group Id
          BG001
          value
          15014
        3. group Id
          BG002
          value
          18
        4. group Id
          BG003
          value
          157
        5. group Id
          BG004
          value
          0
        6. group Id
          BG005
          value
          0
        7. group Id
          BG006
          value
          202
        8. group Id
          BG007
          value
          1132
        9. group Id
          BG008
          value
          0
        10. group Id
          BG009
          value
          0
        11. group Id
          BG010
          value
          50
        12. group Id
          BG011
          value
          399
      title
      7+ units/day
    5. categories
      1. measurements
        1. group Id
          BG000
          value
          42661
        2. group Id
          BG001
          value
          451953
        3. group Id
          BG002
          value
          483
        4. group Id
          BG003
          value
          5102
        5. group Id
          BG004
          value
          0
        6. group Id
          BG005
          value
          0
        7. group Id
          BG006
          value
          2712
        8. group Id
          BG007
          value
          26621
        9. group Id
          BG008
          value
          0
        10. group Id
          BG009
          value
          0
        11. group Id
          BG010
          value
          4447
        12. group Id
          BG011
          value
          45194
      title
      Missing
    description
    One unit of alcohol was defined as the equivalent of 10 milliliters (ml) of ethyl alcohol. A zero (0) has been entered for the cases and controls of the following cancers because data were not collected in participants: anal, bone/joint, penile, bladder, other nervous system, pancreatic, and renal.
    param Type
    NUMBER
    title
    Number of participants with the indicated alcohol consumption (per day)
    unit Of Measure
    participants
  8. classes
    1. categories
      1. measurements
        1. group Id
          BG000
          value
          0
        2. group Id
          BG001
          value
          0
        3. group Id
          BG002
          value
          796
        4. group Id
          BG003
          value
          5202
        5. group Id
          BG004
          value
          0
        6. group Id
          BG005
          value
          0
        7. group Id
          BG006
          value
          0
        8. group Id
          BG007
          value
          0
        9. group Id
          BG008
          value
          0
        10. group Id
          BG009
          value
          0
        11. group Id
          BG010
          value
          0
        12. group Id
          BG011
          value
          0
      title
      Acid suppressing drugs (>6 mo. before index date)
    2. categories
      1. measurements
        1. group Id
          BG000
          value
          87337
        2. group Id
          BG001
          value
          765861
        3. group Id
          BG002
          value
          924
        4. group Id
          BG003
          value
          7779
        5. group Id
          BG004
          value
          92
        6. group Id
          BG005
          value
          924
        7. group Id
          BG006
          value
          5626
        8. group Id
          BG007
          value
          46417
        9. group Id
          BG008
          value
          130
        10. group Id
          BG009
          value
          1008
        11. group Id
          BG010
          value
          9603
        12. group Id
          BG011
          value
          91302
      title
      Back pain
    3. categories
      1. measurements
        1. group Id
          BG000
          value
          0
        2. group Id
          BG001
          value
          0
        3. group Id
          BG002
          value
          0
        4. group Id
          BG003
          value
          0
        5. group Id
          BG004
          value
          0
        6. group Id
          BG005
          value
          0
        7. group Id
          BG006
          value
          0
        8. group Id
          BG007
          value
          0
        9. group Id
          BG008
          value
          0
        10. group Id
          BG009
          value
          0
        11. group Id
          BG010
          value
          894
        12. group Id
          BG011
          value
          5508
      title
      Benign breast disease
    4. categories
      1. measurements
        1. group Id
          BG000
          value
          0
        2. group Id
          BG001
          value
          0
        3. group Id
          BG002
          value
          0
        4. group Id
          BG003
          value
          0
        5. group Id
          BG004
          value
          0
        6. group Id
          BG005
          value
          0
        7. group Id
          BG006
          value
          2532
        8. group Id
          BG007
          value
          6639
        9. group Id
          BG008
          value
          0
        10. group Id
          BG009
          value
          0
        11. group Id
          BG010
          value
          0
        12. group Id
          BG011
          value
          0
      title
      Chronic obstructive pulmonary disease (COPD)
    5. categories
      1. measurements
        1. group Id
          BG000
          value
          0
        2. group Id
          BG001
          value
          0
        3. group Id
          BG002
          value
          0
        4. group Id
          BG003
          value
          0
        5. group Id
          BG004
          value
          0
        6. group Id
          BG005
          value
          0
        7. group Id
          BG006
          value
          0
        8. group Id
          BG007
          value
          0
        9. group Id
          BG008
          value
          0
        10. group Id
          BG009
          value
          0
        11. group Id
          BG010
          value
          0
        12. group Id
          BG011
          value
          0
      title
      Chronic pancreatitis
    6. categories
      1. measurements
        1. group Id
          BG000
          value
          0
        2. group Id
          BG001
          value
          0
        3. group Id
          BG002
          value
          0
        4. group Id
          BG003
          value
          0
        5. group Id
          BG004
          value
          0
        6. group Id
          BG005
          value
          0
        7. group Id
          BG006
          value
          0
        8. group Id
          BG007
          value
          0
        9. group Id
          BG008
          value
          0
        10. group Id
          BG009
          value
          0
        11. group Id
          BG010
          value
          2916
        12. group Id
          BG011
          value
          22576
      title
      Current estrogen (within 6 months of index date)
    7. categories
      1. measurements
        1. group Id
          BG000
          value
          15280
        2. group Id
          BG001
          value
          130210
        3. group Id
          BG002
          value
          208
        4. group Id
          BG003
          value
          1592
        5. group Id
          BG004
          value
          17
        6. group Id
          BG005
          value
          139
        7. group Id
          BG006
          value
          1086
        8. group Id
          BG007
          value
          9448
        9. group Id
          BG008
          value
          15
        10. group Id
          BG009
          value
          155
        11. group Id
          BG010
          value
          1162
        12. group Id
          BG011
          value
          9899
      title
      Diabetes
    8. categories
      1. measurements
        1. group Id
          BG000
          value
          0
        2. group Id
          BG001
          value
          0
        3. group Id
          BG002
          value
          0
        4. group Id
          BG003
          value
          0
        5. group Id
          BG004
          value
          0
        6. group Id
          BG005
          value
          0
        7. group Id
          BG006
          value
          0
        8. group Id
          BG007
          value
          0
        9. group Id
          BG008
          value
          0
        10. group Id
          BG009
          value
          0
        11. group Id
          BG010
          value
          0
        12. group Id
          BG011
          value
          0
      title
      Diuretic use (at any time up to the index date)
    9. categories
      1. measurements
        1. group Id
          BG000
          value
          3015
        2. group Id
          BG001
          value
          24226
        3. group Id
          BG002
          value
          32
        4. group Id
          BG003
          value
          271
        5. group Id
          BG004
          value
          8
        6. group Id
          BG005
          value
          23
        7. group Id
          BG006
          value
          214
        8. group Id
          BG007
          value
          1577
        9. group Id
          BG008
          value
          3
        10. group Id
          BG009
          value
          33
        11. group Id
          BG010
          value
          285
        12. group Id
          BG011
          value
          2486
      title
      Epilepsy
    10. categories
      1. measurements
        1. group Id
          BG000
          value
          0
        2. group Id
          BG001
          value
          0
        3. group Id
          BG002
          value
          0
        4. group Id
          BG003
          value
          0
        5. group Id
          BG004
          value
          3
        6. group Id
          BG005
          value
          0
        7. group Id
          BG006
          value
          0
        8. group Id
          BG007
          value
          0
        9. group Id
          BG008
          value
          0
        10. group Id
          BG009
          value
          0
        11. group Id
          BG010
          value
          0
        12. group Id
          BG011
          value
          0
      title
      Human immunodeficiency virus (HIV)
    11. categories
      1. measurements
        1. group Id
          BG000
          value
          0
        2. group Id
          BG001
          value
          0
        3. group Id
          BG002
          value
          0
        4. group Id
          BG003
          value
          0
        5. group Id
          BG004
          value
          15
        6. group Id
          BG005
          value
          7
        7. group Id
          BG006
          value
          0
        8. group Id
          BG007
          value
          0
        9. group Id
          BG008
          value
          0
        10. group Id
          BG009
          value
          0
        11. group Id
          BG010
          value
          0
        12. group Id
          BG011
          value
          0
      title
      Human papillomavirus (HPV) (genital)
    12. categories
      1. measurements
        1. group Id
          BG000
          value
          0
        2. group Id
          BG001
          value
          0
        3. group Id
          BG002
          value
          0
        4. group Id
          BG003
          value
          0
        5. group Id
          BG004
          value
          0
        6. group Id
          BG005
          value
          0
        7. group Id
          BG006
          value
          0
        8. group Id
          BG007
          value
          0
        9. group Id
          BG008
          value
          0
        10. group Id
          BG009
          value
          0
        11. group Id
          BG010
          value
          0
        12. group Id
          BG011
          value
          0
      title
      Hypertension
    description
    Medication use was defined by British National Formulary codes for the medications. Comorbid conditions were defined by READ/OXMIS codes at any time up to the index date, except for diabetes, which was assessed up to 2 years prior to index date for the pancreatic cancer analysis. A zero (0) indicates that data were not collected for the respective comorbidity, except for the following: HIV (Anal Cancer Controls, Penile Cancer Cases \& Controls,) and Epilepsy (Penile Cancer Cases). mo., months.
    param Type
    NUMBER
    title
    Number of participants using indicated class of medications or having the indicated comorbidities
    unit Of Measure
    participants

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Preserved source evidence · Not medical advice