NCT01210222 · OUTCOME
Adverse Events as Assessed by NCI CTCAE v 4.0
Trebananib in Treating Patients With Persistent or Recurrent Endometrial Cancer · Source last updated 2018-02-23
Results reported by the registry submitting party. Population, time horizon, units and missing values must be read together.
- Measure
- COUNT_OF_PARTICIPANTS
- Unit
- Participants
- Interval / dispersion
- Not reported
- Time frame
- Up to 5 years
Analysis population: Eligible and evaluable patients
Groups in this outcome
Grade 0
Number of patients who did not experience the specified AE.
Grade 1 (CTCAE v 4.0)
Number of patients who experienced a grade 1 event using Common Terminology Criteria version 4.0
Grade 2 (CTCAE v 4.0)
Number of patients who experienced a grade 2 event using Common Terminology Criteria version 4.0
Grade 3 (CTCAE v 4.0)
Number of patients who experienced a grade 3 event using Common Terminology Criteria version 4.0
Grade 4 (CTCAE v 4.0)
Number of patients who experienced a grade 4 event using Common Terminology Criteria version 4.0
Grade 5 (CTCAE v 4.0)
Number of patients who experienced a grade 5 event using common terminology criteria version 4.0
Group identifiers and denominators belong to this outcome only. They may differ in another outcome or in safety reporting.
Analysis denominator · Participants
| Group | Source count |
|---|
| Grade 0 | 32 |
|---|
| Grade 1 (CTCAE v 4.0) | 32 |
|---|
| Grade 2 (CTCAE v 4.0) | 32 |
|---|
| Grade 3 (CTCAE v 4.0) | 32 |
|---|
| Grade 4 (CTCAE v 4.0) | 32 |
|---|
| Grade 5 (CTCAE v 4.0) | 32 |
|---|
Reported measurements
Fatigue
Values in Participants · Interval/dispersion: Not reported| Group | Value | Spread | Lower | Upper | Comment |
|---|
| Grade 0 | 10 | Not reported | Not reported | Not reported | Not reported |
|---|
| Grade 1 (CTCAE v 4.0) | 11 | Not reported | Not reported | Not reported | Not reported |
|---|
| Grade 2 (CTCAE v 4.0) | 9 | Not reported | Not reported | Not reported | Not reported |
|---|
| Grade 3 (CTCAE v 4.0) | 2 | Not reported | Not reported | Not reported | Not reported |
|---|
| Grade 4 (CTCAE v 4.0) | 0 | Not reported | Not reported | Not reported | Not reported |
|---|
| Grade 5 (CTCAE v 4.0) | 0 | Not reported | Not reported | Not reported | Not reported |
|---|
Anemia
Values in Participants · Interval/dispersion: Not reported| Group | Value | Spread | Lower | Upper | Comment |
|---|
| Grade 0 | 15 | Not reported | Not reported | Not reported | Not reported |
|---|
| Grade 1 (CTCAE v 4.0) | 15 | Not reported | Not reported | Not reported | Not reported |
|---|
| Grade 2 (CTCAE v 4.0) | 2 | Not reported | Not reported | Not reported | Not reported |
|---|
| Grade 3 (CTCAE v 4.0) | 0 | Not reported | Not reported | Not reported | Not reported |
|---|
| Grade 4 (CTCAE v 4.0) | 0 | Not reported | Not reported | Not reported | Not reported |
|---|
| Grade 5 (CTCAE v 4.0) | 0 | Not reported | Not reported | Not reported | Not reported |
|---|
Constipation
Values in Participants · Interval/dispersion: Not reported| Group | Value | Spread | Lower | Upper | Comment |
|---|
| Grade 0 | 16 | Not reported | Not reported | Not reported | Not reported |
|---|
| Grade 1 (CTCAE v 4.0) | 10 | Not reported | Not reported | Not reported | Not reported |
|---|
| Grade 2 (CTCAE v 4.0) | 6 | Not reported | Not reported | Not reported | Not reported |
|---|
| Grade 3 (CTCAE v 4.0) | 0 | Not reported | Not reported | Not reported | Not reported |
|---|
| Grade 4 (CTCAE v 4.0) | 0 | Not reported | Not reported | Not reported | Not reported |
|---|
| Grade 5 (CTCAE v 4.0) | 0 | Not reported | Not reported | Not reported | Not reported |
|---|
Hypertension
Values in Participants · Interval/dispersion: Not reported| Group | Value | Spread | Lower | Upper | Comment |
|---|
| Grade 0 | 20 | Not reported | Not reported | Not reported | Not reported |
|---|
| Grade 1 (CTCAE v 4.0) | 1 | Not reported | Not reported | Not reported | Not reported |
|---|
| Grade 2 (CTCAE v 4.0) | 7 | Not reported | Not reported | Not reported | Not reported |
|---|
| Grade 3 (CTCAE v 4.0) | 4 | Not reported | Not reported | Not reported | Not reported |
|---|
| Grade 4 (CTCAE v 4.0) | 0 | Not reported | Not reported | Not reported | Not reported |
|---|
| Grade 5 (CTCAE v 4.0) | 0 | Not reported | Not reported | Not reported | Not reported |
|---|
Nausea
Values in Participants · Interval/dispersion: Not reported| Group | Value | Spread | Lower | Upper | Comment |
|---|
| Grade 0 | 20 | Not reported | Not reported | Not reported | Not reported |
|---|
| Grade 1 (CTCAE v 4.0) | 6 | Not reported | Not reported | Not reported | Not reported |
|---|
| Grade 2 (CTCAE v 4.0) | 2 | Not reported | Not reported | Not reported | Not reported |
|---|
| Grade 3 (CTCAE v 4.0) | 4 | Not reported | Not reported | Not reported | Not reported |
|---|
| Grade 4 (CTCAE v 4.0) | 0 | Not reported | Not reported | Not reported | Not reported |
|---|
| Grade 5 (CTCAE v 4.0) | 0 | Not reported | Not reported | Not reported | Not reported |
|---|
Abdominal Pain
Values in Participants · Interval/dispersion: Not reported| Group | Value | Spread | Lower | Upper | Comment |
|---|
| Grade 0 | 20 | Not reported | Not reported | Not reported | Not reported |
|---|
| Grade 1 (CTCAE v 4.0) | 1 | Not reported | Not reported | Not reported | Not reported |
|---|
| Grade 2 (CTCAE v 4.0) | 3 | Not reported | Not reported | Not reported | Not reported |
|---|
| Grade 3 (CTCAE v 4.0) | 8 | Not reported | Not reported | Not reported | Not reported |
|---|
| Grade 4 (CTCAE v 4.0) | 0 | Not reported | Not reported | Not reported | Not reported |
|---|
| Grade 5 (CTCAE v 4.0) | 0 | Not reported | Not reported | Not reported | Not reported |
|---|
Edema Limbs
Values in Participants · Interval/dispersion: Not reported| Group | Value | Spread | Lower | Upper | Comment |
|---|
| Grade 0 | 21 | Not reported | Not reported | Not reported | Not reported |
|---|
| Grade 1 (CTCAE v 4.0) | 4 | Not reported | Not reported | Not reported | Not reported |
|---|
| Grade 2 (CTCAE v 4.0) | 5 | Not reported | Not reported | Not reported | Not reported |
|---|
| Grade 3 (CTCAE v 4.0) | 2 | Not reported | Not reported | Not reported | Not reported |
|---|
| Grade 4 (CTCAE v 4.0) | 0 | Not reported | Not reported | Not reported | Not reported |
|---|
| Grade 5 (CTCAE v 4.0) | 0 | Not reported | Not reported | Not reported | Not reported |
|---|
Anorexia
Values in Participants · Interval/dispersion: Not reported| Group | Value | Spread | Lower | Upper | Comment |
|---|
| Grade 0 | 22 | Not reported | Not reported | Not reported | Not reported |
|---|
| Grade 1 (CTCAE v 4.0) | 6 | Not reported | Not reported | Not reported | Not reported |
|---|
| Grade 2 (CTCAE v 4.0) | 3 | Not reported | Not reported | Not reported | Not reported |
|---|
| Grade 3 (CTCAE v 4.0) | 1 | Not reported | Not reported | Not reported | Not reported |
|---|
| Grade 4 (CTCAE v 4.0) | 0 | Not reported | Not reported | Not reported | Not reported |
|---|
| Grade 5 (CTCAE v 4.0) | 0 | Not reported | Not reported | Not reported | Not reported |
|---|
Peripheral Sensory Neuropathy
Values in Participants · Interval/dispersion: Not reported| Group | Value | Spread | Lower | Upper | Comment |
|---|
| Grade 0 | 22 | Not reported | Not reported | Not reported | Not reported |
|---|
| Grade 1 (CTCAE v 4.0) | 10 | Not reported | Not reported | Not reported | Not reported |
|---|
| Grade 2 (CTCAE v 4.0) | 0 | Not reported | Not reported | Not reported | Not reported |
|---|
| Grade 3 (CTCAE v 4.0) | 0 | Not reported | Not reported | Not reported | Not reported |
|---|
| Grade 4 (CTCAE v 4.0) | 0 | Not reported | Not reported | Not reported | Not reported |
|---|
| Grade 5 (CTCAE v 4.0) | 0 | Not reported | Not reported | Not reported | Not reported |
|---|
Cough
Values in Participants · Interval/dispersion: Not reported| Group | Value | Spread | Lower | Upper | Comment |
|---|
| Grade 0 | 24 | Not reported | Not reported | Not reported | Not reported |
|---|
| Grade 1 (CTCAE v 4.0) | 7 | Not reported | Not reported | Not reported | Not reported |
|---|
| Grade 2 (CTCAE v 4.0) | 1 | Not reported | Not reported | Not reported | Not reported |
|---|
| Grade 3 (CTCAE v 4.0) | 0 | Not reported | Not reported | Not reported | Not reported |
|---|
| Grade 4 (CTCAE v 4.0) | 0 | Not reported | Not reported | Not reported | Not reported |
|---|
| Grade 5 (CTCAE v 4.0) | 0 | Not reported | Not reported | Not reported | Not reported |
|---|
Diarrhea
Values in Participants · Interval/dispersion: Not reported| Group | Value | Spread | Lower | Upper | Comment |
|---|
| Grade 0 | 24 | Not reported | Not reported | Not reported | Not reported |
|---|
| Grade 1 (CTCAE v 4.0) | 6 | Not reported | Not reported | Not reported | Not reported |
|---|
| Grade 2 (CTCAE v 4.0) | 2 | Not reported | Not reported | Not reported | Not reported |
|---|
| Grade 3 (CTCAE v 4.0) | 0 | Not reported | Not reported | Not reported | Not reported |
|---|
| Grade 4 (CTCAE v 4.0) | 0 | Not reported | Not reported | Not reported | Not reported |
|---|
| Grade 5 (CTCAE v 4.0) | 0 | Not reported | Not reported | Not reported | Not reported |
|---|
Hyperglycemia
Values in Participants · Interval/dispersion: Not reported| Group | Value | Spread | Lower | Upper | Comment |
|---|
| Grade 0 | 24 | Not reported | Not reported | Not reported | Not reported |
|---|
| Grade 1 (CTCAE v 4.0) | 6 | Not reported | Not reported | Not reported | Not reported |
|---|
| Grade 2 (CTCAE v 4.0) | 2 | Not reported | Not reported | Not reported | Not reported |
|---|
| Grade 3 (CTCAE v 4.0) | 0 | Not reported | Not reported | Not reported | Not reported |
|---|
| Grade 4 (CTCAE v 4.0) | 0 | Not reported | Not reported | Not reported | Not reported |
|---|
| Grade 5 (CTCAE v 4.0) | 0 | Not reported | Not reported | Not reported | Not reported |
|---|
Hyponatremia
Values in Participants · Interval/dispersion: Not reported| Group | Value | Spread | Lower | Upper | Comment |
|---|
| Grade 0 | 24 | Not reported | Not reported | Not reported | Not reported |
|---|
| Grade 1 (CTCAE v 4.0) | 5 | Not reported | Not reported | Not reported | Not reported |
|---|
| Grade 2 (CTCAE v 4.0) | 0 | Not reported | Not reported | Not reported | Not reported |
|---|
| Grade 3 (CTCAE v 4.0) | 2 | Not reported | Not reported | Not reported | Not reported |
|---|
| Grade 4 (CTCAE v 4.0) | 1 | Not reported | Not reported | Not reported | Not reported |
|---|
| Grade 5 (CTCAE v 4.0) | 0 | Not reported | Not reported | Not reported | Not reported |
|---|
Hypoalbuminemia
Values in Participants · Interval/dispersion: Not reported| Group | Value | Spread | Lower | Upper | Comment |
|---|
| Grade 0 | 24 | Not reported | Not reported | Not reported | Not reported |
|---|
| Grade 1 (CTCAE v 4.0) | 3 | Not reported | Not reported | Not reported | Not reported |
|---|
| Grade 2 (CTCAE v 4.0) | 3 | Not reported | Not reported | Not reported | Not reported |
|---|
| Grade 3 (CTCAE v 4.0) | 2 | Not reported | Not reported | Not reported | Not reported |
|---|
| Grade 4 (CTCAE v 4.0) | 0 | Not reported | Not reported | Not reported | Not reported |
|---|
| Grade 5 (CTCAE v 4.0) | 0 | Not reported | Not reported | Not reported | Not reported |
|---|
Dyspnea
Values in Participants · Interval/dispersion: Not reported| Group | Value | Spread | Lower | Upper | Comment |
|---|
| Grade 0 | 25 | Not reported | Not reported | Not reported | Not reported |
|---|
| Grade 1 (CTCAE v 4.0) | 4 | Not reported | Not reported | Not reported | Not reported |
|---|
| Grade 2 (CTCAE v 4.0) | 1 | Not reported | Not reported | Not reported | Not reported |
|---|
| Grade 3 (CTCAE v 4.0) | 2 | Not reported | Not reported | Not reported | Not reported |
|---|
| Grade 4 (CTCAE v 4.0) | 0 | Not reported | Not reported | Not reported | Not reported |
|---|
| Grade 5 (CTCAE v 4.0) | 0 | Not reported | Not reported | Not reported | Not reported |
|---|
Vomiting
Values in Participants · Interval/dispersion: Not reported| Group | Value | Spread | Lower | Upper | Comment |
|---|
| Grade 0 | 25 | Not reported | Not reported | Not reported | Not reported |
|---|
| Grade 1 (CTCAE v 4.0) | 2 | Not reported | Not reported | Not reported | Not reported |
|---|
| Grade 2 (CTCAE v 4.0) | 3 | Not reported | Not reported | Not reported | Not reported |
|---|
| Grade 3 (CTCAE v 4.0) | 2 | Not reported | Not reported | Not reported | Not reported |
|---|
| Grade 4 (CTCAE v 4.0) | 0 | Not reported | Not reported | Not reported | Not reported |
|---|
| Grade 5 (CTCAE v 4.0) | 0 | Not reported | Not reported | Not reported | Not reported |
|---|
Ascites
Values in Participants · Interval/dispersion: Not reported| Group | Value | Spread | Lower | Upper | Comment |
|---|
| Grade 0 | 27 | Not reported | Not reported | Not reported | Not reported |
|---|
| Grade 1 (CTCAE v 4.0) | 0 | Not reported | Not reported | Not reported | Not reported |
|---|
| Grade 2 (CTCAE v 4.0) | 2 | Not reported | Not reported | Not reported | Not reported |
|---|
| Grade 3 (CTCAE v 4.0) | 3 | Not reported | Not reported | Not reported | Not reported |
|---|
| Grade 4 (CTCAE v 4.0) | 0 | Not reported | Not reported | Not reported | Not reported |
|---|
| Grade 5 (CTCAE v 4.0) | 0 | Not reported | Not reported | Not reported | Not reported |
|---|
Bloating
Values in Participants · Interval/dispersion: Not reported| Group | Value | Spread | Lower | Upper | Comment |
|---|
| Grade 0 | 28 | Not reported | Not reported | Not reported | Not reported |
|---|
| Grade 1 (CTCAE v 4.0) | 1 | Not reported | Not reported | Not reported | Not reported |
|---|
| Grade 2 (CTCAE v 4.0) | 3 | Not reported | Not reported | Not reported | Not reported |
|---|
| Grade 3 (CTCAE v 4.0) | 0 | Not reported | Not reported | Not reported | Not reported |
|---|
| Grade 4 (CTCAE v 4.0) | 0 | Not reported | Not reported | Not reported | Not reported |
|---|
| Grade 5 (CTCAE v 4.0) | 0 | Not reported | Not reported | Not reported | Not reported |
|---|
Lymphedema
Values in Participants · Interval/dispersion: Not reported| Group | Value | Spread | Lower | Upper | Comment |
|---|
| Grade 0 | 28 | Not reported | Not reported | Not reported | Not reported |
|---|
| Grade 1 (CTCAE v 4.0) | 1 | Not reported | Not reported | Not reported | Not reported |
|---|
| Grade 2 (CTCAE v 4.0) | 1 | Not reported | Not reported | Not reported | Not reported |
|---|
| Grade 3 (CTCAE v 4.0) | 2 | Not reported | Not reported | Not reported | Not reported |
|---|
| Grade 4 (CTCAE v 4.0) | 0 | Not reported | Not reported | Not reported | Not reported |
|---|
| Grade 5 (CTCAE v 4.0) | 0 | Not reported | Not reported | Not reported | Not reported |
|---|
Thromboembolic Event
Values in Participants · Interval/dispersion: Not reported| Group | Value | Spread | Lower | Upper | Comment |
|---|
| Grade 0 | 28 | Not reported | Not reported | Not reported | Not reported |
|---|
| Grade 1 (CTCAE v 4.0) | 0 | Not reported | Not reported | Not reported | Not reported |
|---|
| Grade 2 (CTCAE v 4.0) | 2 | Not reported | Not reported | Not reported | Not reported |
|---|
| Grade 3 (CTCAE v 4.0) | 2 | Not reported | Not reported | Not reported | Not reported |
|---|
| Grade 4 (CTCAE v 4.0) | 0 | Not reported | Not reported | Not reported | Not reported |
|---|
| Grade 5 (CTCAE v 4.0) | 0 | Not reported | Not reported | Not reported | Not reported |
|---|
Localized Edema
Values in Participants · Interval/dispersion: Not reported| Group | Value | Spread | Lower | Upper | Comment |
|---|
| Grade 0 | 29 | Not reported | Not reported | Not reported | Not reported |
|---|
| Grade 1 (CTCAE v 4.0) | 3 | Not reported | Not reported | Not reported | Not reported |
|---|
| Grade 2 (CTCAE v 4.0) | 0 | Not reported | Not reported | Not reported | Not reported |
|---|
| Grade 3 (CTCAE v 4.0) | 0 | Not reported | Not reported | Not reported | Not reported |
|---|
| Grade 4 (CTCAE v 4.0) | 0 | Not reported | Not reported | Not reported | Not reported |
|---|
| Grade 5 (CTCAE v 4.0) | 0 | Not reported | Not reported | Not reported | Not reported |
|---|
Complete source fields
- classes
- categories
- measurements
- group Id
- OG000
- value
- 10
- group Id
- OG001
- value
- 11
- group Id
- OG002
- value
- 9
- group Id
- OG003
- value
- 2
- group Id
- OG004
- value
- 0
- group Id
- OG005
- value
- 0
- title
- Fatigue
- categories
- measurements
- group Id
- OG000
- value
- 15
- group Id
- OG001
- value
- 15
- group Id
- OG002
- value
- 2
- group Id
- OG003
- value
- 0
- group Id
- OG004
- value
- 0
- group Id
- OG005
- value
- 0
- title
- Anemia
- categories
- measurements
- group Id
- OG000
- value
- 16
- group Id
- OG001
- value
- 10
- group Id
- OG002
- value
- 6
- group Id
- OG003
- value
- 0
- group Id
- OG004
- value
- 0
- group Id
- OG005
- value
- 0
- title
- Constipation
- categories
- measurements
- group Id
- OG000
- value
- 20
- group Id
- OG001
- value
- 1
- group Id
- OG002
- value
- 7
- group Id
- OG003
- value
- 4
- group Id
- OG004
- value
- 0
- group Id
- OG005
- value
- 0
- title
- Hypertension
- categories
- measurements
- group Id
- OG000
- value
- 20
- group Id
- OG001
- value
- 6
- group Id
- OG002
- value
- 2
- group Id
- OG003
- value
- 4
- group Id
- OG004
- value
- 0
- group Id
- OG005
- value
- 0
- title
- Nausea
- categories
- measurements
- group Id
- OG000
- value
- 20
- group Id
- OG001
- value
- 1
- group Id
- OG002
- value
- 3
- group Id
- OG003
- value
- 8
- group Id
- OG004
- value
- 0
- group Id
- OG005
- value
- 0
- title
- Abdominal Pain
- categories
- measurements
- group Id
- OG000
- value
- 21
- group Id
- OG001
- value
- 4
- group Id
- OG002
- value
- 5
- group Id
- OG003
- value
- 2
- group Id
- OG004
- value
- 0
- group Id
- OG005
- value
- 0
- title
- Edema Limbs
- categories
- measurements
- group Id
- OG000
- value
- 22
- group Id
- OG001
- value
- 6
- group Id
- OG002
- value
- 3
- group Id
- OG003
- value
- 1
- group Id
- OG004
- value
- 0
- group Id
- OG005
- value
- 0
- title
- Anorexia
- categories
- measurements
- group Id
- OG000
- value
- 22
- group Id
- OG001
- value
- 10
- group Id
- OG002
- value
- 0
- group Id
- OG003
- value
- 0
- group Id
- OG004
- value
- 0
- group Id
- OG005
- value
- 0
- title
- Peripheral Sensory Neuropathy
- categories
- measurements
- group Id
- OG000
- value
- 24
- group Id
- OG001
- value
- 7
- group Id
- OG002
- value
- 1
- group Id
- OG003
- value
- 0
- group Id
- OG004
- value
- 0
- group Id
- OG005
- value
- 0
- title
- Cough
- categories
- measurements
- group Id
- OG000
- value
- 24
- group Id
- OG001
- value
- 6
- group Id
- OG002
- value
- 2
- group Id
- OG003
- value
- 0
- group Id
- OG004
- value
- 0
- group Id
- OG005
- value
- 0
- title
- Diarrhea
- categories
- measurements
- group Id
- OG000
- value
- 24
- group Id
- OG001
- value
- 6
- group Id
- OG002
- value
- 2
- group Id
- OG003
- value
- 0
- group Id
- OG004
- value
- 0
- group Id
- OG005
- value
- 0
- title
- Hyperglycemia
- denoms
- counts
- group Id
- OG000
- value
- 32
- group Id
- OG001
- value
- 32
- group Id
- OG002
- value
- 32
- group Id
- OG003
- value
- 32
- group Id
- OG004
- value
- 32
- group Id
- OG005
- value
- 32
- units
- Participants
- groups
- description
- Number of patients who did not experience the specified AE.
- id
- OG000
- title
- Grade 0
- description
- Number of patients who experienced a grade 1 event using Common Terminology Criteria version 4.0
- id
- OG001
- title
- Grade 1 (CTCAE v 4.0)
- description
- Number of patients who experienced a grade 2 event using Common Terminology Criteria version 4.0
- id
- OG002
- title
- Grade 2 (CTCAE v 4.0)
- description
- Number of patients who experienced a grade 3 event using Common Terminology Criteria version 4.0
- id
- OG003
- title
- Grade 3 (CTCAE v 4.0)
- description
- Number of patients who experienced a grade 4 event using Common Terminology Criteria version 4.0
- id
- OG004
- title
- Grade 4 (CTCAE v 4.0)
- description
- Number of patients who experienced a grade 5 event using common terminology criteria version 4.0
- id
- OG005
- title
- Grade 5 (CTCAE v 4.0)
- param Type
- COUNT_OF_PARTICIPANTS
- population Description
- Eligible and evaluable patients
- reporting Status
- POSTED
- time Frame
- Up to 5 years
- title
- Adverse Events as Assessed by NCI CTCAE v 4.0
- type
- PRIMARY
- unit Of Measure
- Participants
Download exact source JSON → · Snapshot ctgov-results-25a395029948b04d52b1253f
Preserved source evidence · Not medical advice
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