NCT01158118 · OUTCOME

Kinetics of Immune Reconstitution as Measured by Time to Platelet Engraftment (Recipient Only)

Plerixafor and Sargramostim (GM-CSF) for Mobilization of Allogeneic Sibling Donors · Source last updated 2017-06-05

Results reported by the registry submitting party. Population, time horizon, units and missing values must be read together.

Measure: MEDIAN
Unit: days
Interval / dispersion: Full Range
Time frame: Up to Day 180

What was measured

-Time to platelet engraftment is measured by determining the first of 3 consecutive measurements of platelet count ≥ 20,000/ul without platelet transfusion support for 7 days.

Analysis population: 1 recipient did not have platelet engraftment by Day 180 and is not evaluable for this outcome measure.

Groups in this outcome

Arm 2 - Recipient

Conditioning Regimens * fludarabine and busulfan +/- thymoglobulin * fractionated total body irradiation and cyclophosphamide * busulfan and cyclophosphamide * single dose total body irradiation and cyclophosphamide Day -2 = GvHD prophylaxis Day 0 or +1 = PBSC transplant Day +7 until neutrophil engraftment = G-CSF 5 ug/kg/day

Group identifiers and denominators belong to this outcome only. They may differ in another outcome or in safety reporting.

Analysis denominator · Participants

Group	Source count
Arm 2 - Recipient	20

Reported measurements

Source class 1

Values in days · Interval/dispersion: Full Range
Group	Value	Spread	Lower	Upper	Comment
Arm 2 - Recipient	22	Not reported	15	106	Not reported

Complete source fields

classes

categories
measurements
group Id
OG000
lower Limit
15
upper Limit
106
value
22

denoms

counts
group Id
OG000
value
20
units
Participants

description

-Time to platelet engraftment is measured by determining the first of 3 consecutive measurements of platelet count ≥ 20,000/ul without platelet transfusion support for 7 days.

dispersion Type

Full Range

groups

description
Conditioning Regimens * fludarabine and busulfan +/- thymoglobulin * fractionated total body irradiation and cyclophosphamide * busulfan and cyclophosphamide * single dose total body irradiation and cyclophosphamide Day -2 = GvHD prophylaxis Day 0 or +1 = PBSC transplant Day +7 until neutrophil engraftment = G-CSF 5 ug/kg/day
id
OG000
title
Arm 2 - Recipient

param Type

MEDIAN

population Description

1 recipient did not have platelet engraftment by Day 180 and is not evaluable for this outcome measure.

reporting Status

POSTED

time Frame

Up to Day 180

title

Kinetics of Immune Reconstitution as Measured by Time to Platelet Engraftment (Recipient Only)

type

SECONDARY

unit Of Measure

days

Download exact source JSON → · Snapshot ctgov-results-25a395029948b04d52b1253f

Preserved source evidence · Not medical advice