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NCT01037790 · BASELINE

Baseline characteristics

Phase II Trial of the Cyclin-Dependent Kinase Inhibitor PD 0332991 in Patients With Cancer · Source last updated 2021-03-11

Results reported by the registry submitting party. Population, time horizon, units and missing values must be read together.

denoms
  1. counts
    1. group Id
      BG000
      value
      63
    2. group Id
      BG001
      value
      18
    3. group Id
      BG002
      value
      19
    4. group Id
      BG003
      value
      30
    5. group Id
      BG004
      value
      11
    6. group Id
      BG005
      value
      141
    units
    Participants
groups
  1. description
    Metastatic breast cancer PD-0332991: Given orally, 125 mg QD on a 21-day
    id
    BG000
    title
    Arm 1
  2. description
    Metastatic colorectal cancer that harbors the Kras or BRAF mutation PD-0332991: Given orally, 125 mg QD on a 21-day
    id
    BG001
    title
    Arm 2
  3. description
    Advanced or metastatic esophageal and/or gastric cancer PD-0332991: Given orally, 125 mg QD on a 21-day
    id
    BG002
    title
    Arm 3
  4. description
    Cisplatin-refractory, unresectable germ cell tumors PD-0332991: Given orally, 125 mg QD on a 21-day
    id
    BG003
    title
    Arm 4
  5. description
    Any tumor type if tissue tests positive for CCND1 amplification, CDK4/6 mutation , CCND2 amplification OR any other functional alteration at the G1/S checkpoint. PD-0332991: Given orally, 125 mg QD on a 21-day
    id
    BG004
    title
    Arm 5
  6. description
    Total of all reporting groups
    id
    BG005
    title
    Total
measures
  1. classes
    1. categories
      1. measurements
        1. group Id
          BG000
          value
          0
        2. group Id
          BG001
          value
          0
        3. group Id
          BG002
          value
          0
        4. group Id
          BG003
          value
          1
        5. group Id
          BG004
          value
          0
        6. group Id
          BG005
          value
          1
        title
        <=18 years
      2. measurements
        1. group Id
          BG000
          value
          48
        2. group Id
          BG001
          value
          10
        3. group Id
          BG002
          value
          11
        4. group Id
          BG003
          value
          29
        5. group Id
          BG004
          value
          11
        6. group Id
          BG005
          value
          109
        title
        Between 18 and 65 years
      3. measurements
        1. group Id
          BG000
          value
          15
        2. group Id
          BG001
          value
          8
        3. group Id
          BG002
          value
          8
        4. group Id
          BG003
          value
          0
        5. group Id
          BG004
          value
          0
        6. group Id
          BG005
          value
          31
        title
        >=65 years
    param Type
    COUNT_OF_PARTICIPANTS
    title
    Age, Categorical
    unit Of Measure
    Participants
  2. classes
    1. categories
      1. measurements
        1. group Id
          BG000
          value
          63
        2. group Id
          BG001
          value
          8
        3. group Id
          BG002
          value
          4
        4. group Id
          BG003
          value
          4
        5. group Id
          BG004
          value
          9
        6. group Id
          BG005
          value
          88
        title
        Female
      2. measurements
        1. group Id
          BG000
          value
          0
        2. group Id
          BG001
          value
          10
        3. group Id
          BG002
          value
          15
        4. group Id
          BG003
          value
          26
        5. group Id
          BG004
          value
          2
        6. group Id
          BG005
          value
          53
        title
        Male
    param Type
    COUNT_OF_PARTICIPANTS
    title
    Sex: Female, Male
    unit Of Measure
    Participants
  3. classes
    1. categories
      1. measurements
        1. group Id
          BG000
          value
          0
        2. group Id
          BG001
          value
          0
        3. group Id
          BG002
          value
          0
        4. group Id
          BG003
          value
          0
        5. group Id
          BG004
          value
          0
        6. group Id
          BG005
          value
          0
      title
      Asian
    2. categories
      1. measurements
        1. group Id
          BG000
          value
          3
        2. group Id
          BG001
          value
          1
        3. group Id
          BG002
          value
          1
        4. group Id
          BG003
          value
          3
        5. group Id
          BG004
          value
          0
        6. group Id
          BG005
          value
          8
      title
      Black
    3. categories
      1. measurements
        1. group Id
          BG000
          value
          2
        2. group Id
          BG001
          value
          1
        3. group Id
          BG002
          value
          0
        4. group Id
          BG003
          value
          4
        5. group Id
          BG004
          value
          0
        6. group Id
          BG005
          value
          7
      title
      Other
    4. categories
      1. measurements
        1. group Id
          BG000
          value
          58
        2. group Id
          BG001
          value
          16
        3. group Id
          BG002
          value
          18
        4. group Id
          BG003
          value
          23
        5. group Id
          BG004
          value
          11
        6. group Id
          BG005
          value
          126
      title
      White
    param Type
    COUNT_OF_PARTICIPANTS
    title
    Race/Ethnicity, Customized
    unit Of Measure
    Participants
  4. classes
    1. categories
      1. measurements
        1. group Id
          BG000
          value
          63
        2. group Id
          BG001
          value
          18
        3. group Id
          BG002
          value
          19
        4. group Id
          BG003
          value
          30
        5. group Id
          BG004
          value
          11
        6. group Id
          BG005
          value
          141
      title
      United States
    param Type
    NUMBER
    title
    Region of Enrollment
    unit Of Measure
    participants
Complete source fields
denoms
  1. counts
    1. group Id
      BG000
      value
      63
    2. group Id
      BG001
      value
      18
    3. group Id
      BG002
      value
      19
    4. group Id
      BG003
      value
      30
    5. group Id
      BG004
      value
      11
    6. group Id
      BG005
      value
      141
    units
    Participants
groups
  1. description
    Metastatic breast cancer PD-0332991: Given orally, 125 mg QD on a 21-day
    id
    BG000
    title
    Arm 1
  2. description
    Metastatic colorectal cancer that harbors the Kras or BRAF mutation PD-0332991: Given orally, 125 mg QD on a 21-day
    id
    BG001
    title
    Arm 2
  3. description
    Advanced or metastatic esophageal and/or gastric cancer PD-0332991: Given orally, 125 mg QD on a 21-day
    id
    BG002
    title
    Arm 3
  4. description
    Cisplatin-refractory, unresectable germ cell tumors PD-0332991: Given orally, 125 mg QD on a 21-day
    id
    BG003
    title
    Arm 4
  5. description
    Any tumor type if tissue tests positive for CCND1 amplification, CDK4/6 mutation , CCND2 amplification OR any other functional alteration at the G1/S checkpoint. PD-0332991: Given orally, 125 mg QD on a 21-day
    id
    BG004
    title
    Arm 5
  6. description
    Total of all reporting groups
    id
    BG005
    title
    Total
measures
  1. classes
    1. categories
      1. measurements
        1. group Id
          BG000
          value
          0
        2. group Id
          BG001
          value
          0
        3. group Id
          BG002
          value
          0
        4. group Id
          BG003
          value
          1
        5. group Id
          BG004
          value
          0
        6. group Id
          BG005
          value
          1
        title
        <=18 years
      2. measurements
        1. group Id
          BG000
          value
          48
        2. group Id
          BG001
          value
          10
        3. group Id
          BG002
          value
          11
        4. group Id
          BG003
          value
          29
        5. group Id
          BG004
          value
          11
        6. group Id
          BG005
          value
          109
        title
        Between 18 and 65 years
      3. measurements
        1. group Id
          BG000
          value
          15
        2. group Id
          BG001
          value
          8
        3. group Id
          BG002
          value
          8
        4. group Id
          BG003
          value
          0
        5. group Id
          BG004
          value
          0
        6. group Id
          BG005
          value
          31
        title
        >=65 years
    param Type
    COUNT_OF_PARTICIPANTS
    title
    Age, Categorical
    unit Of Measure
    Participants
  2. classes
    1. categories
      1. measurements
        1. group Id
          BG000
          value
          63
        2. group Id
          BG001
          value
          8
        3. group Id
          BG002
          value
          4
        4. group Id
          BG003
          value
          4
        5. group Id
          BG004
          value
          9
        6. group Id
          BG005
          value
          88
        title
        Female
      2. measurements
        1. group Id
          BG000
          value
          0
        2. group Id
          BG001
          value
          10
        3. group Id
          BG002
          value
          15
        4. group Id
          BG003
          value
          26
        5. group Id
          BG004
          value
          2
        6. group Id
          BG005
          value
          53
        title
        Male
    param Type
    COUNT_OF_PARTICIPANTS
    title
    Sex: Female, Male
    unit Of Measure
    Participants
  3. classes
    1. categories
      1. measurements
        1. group Id
          BG000
          value
          0
        2. group Id
          BG001
          value
          0
        3. group Id
          BG002
          value
          0
        4. group Id
          BG003
          value
          0
        5. group Id
          BG004
          value
          0
        6. group Id
          BG005
          value
          0
      title
      Asian
    2. categories
      1. measurements
        1. group Id
          BG000
          value
          3
        2. group Id
          BG001
          value
          1
        3. group Id
          BG002
          value
          1
        4. group Id
          BG003
          value
          3
        5. group Id
          BG004
          value
          0
        6. group Id
          BG005
          value
          8
      title
      Black
    3. categories
      1. measurements
        1. group Id
          BG000
          value
          2
        2. group Id
          BG001
          value
          1
        3. group Id
          BG002
          value
          0
        4. group Id
          BG003
          value
          4
        5. group Id
          BG004
          value
          0
        6. group Id
          BG005
          value
          7
      title
      Other
    4. categories
      1. measurements
        1. group Id
          BG000
          value
          58
        2. group Id
          BG001
          value
          16
        3. group Id
          BG002
          value
          18
        4. group Id
          BG003
          value
          23
        5. group Id
          BG004
          value
          11
        6. group Id
          BG005
          value
          126
      title
      White
    param Type
    COUNT_OF_PARTICIPANTS
    title
    Race/Ethnicity, Customized
    unit Of Measure
    Participants
  4. classes
    1. categories
      1. measurements
        1. group Id
          BG000
          value
          63
        2. group Id
          BG001
          value
          18
        3. group Id
          BG002
          value
          19
        4. group Id
          BG003
          value
          30
        5. group Id
          BG004
          value
          11
        6. group Id
          BG005
          value
          141
      title
      United States
    param Type
    NUMBER
    title
    Region of Enrollment
    unit Of Measure
    participants

Download exact source JSON → · Snapshot ctgov-results-25a395029948b04d52b1253f

Preserved source evidence · Not medical advice