NCT00967343 · OUTCOME

Incidence and Severity Graft-versus-host Disease (GVHD)

Efficacy and Safety of a Donor Lymphocyte Preparation Depleted of Functional Host Alloreactive T-cells (ATIR) in Patients Undergoing a Peripheral Blood Stem Cell Transplant From a Related, Haploidentical Donor · Source last updated 2021-06-14

Results reported by the registry submitting party. Population, time horizon, units and missing values must be read together.

Measure: NUMBER
Unit: Percentage of participants
Interval / dispersion: Not reported
Time frame: Up to 24 months after the transplantation

What was measured

GVHD was graded according to standard criteria as referred to in the reference module (Filipovich et al. 2005; Przepiorka et al. 1995).

Groups in this outcome

ATIR

Donor lymphocyte preparation depleted of host functional alloreactive T-cells: Single intravenous infusion with 2x10E6 T-cells/kg

Group identifiers and denominators belong to this outcome only. They may differ in another outcome or in safety reporting.

Analysis denominator · Participants

Group	Source count
ATIR	40

Reported measurements

Grade II acute GVHD (moderate)

Values in Percentage of participants · Interval/dispersion: Not reported
Group	Value	Spread	Lower	Upper	Comment
ATIR	7.5	Not reported	Not reported	Not reported	Not reported

Grade III (moderate) or IV (severe) acute GVHD

Values in Percentage of participants · Interval/dispersion: Not reported
Group	Value	Spread	Lower	Upper	Comment
ATIR	12.5	Not reported	Not reported	Not reported	Not reported

Severe chronic GVHD

Values in Percentage of participants · Interval/dispersion: Not reported
Group	Value	Spread	Lower	Upper	Comment
ATIR	5	Not reported	Not reported	Not reported	Not reported

Complete source fields

classes

categories
measurements
group Id
OG000
value
7.5
title
Grade II acute GVHD (moderate)
categories
measurements
group Id
OG000
value
12.5
title
Grade III (moderate) or IV (severe) acute GVHD
categories
measurements
group Id
OG000
value
5
title
Severe chronic GVHD

denoms

counts
group Id
OG000
value
40
units
Participants

description

GVHD was graded according to standard criteria as referred to in the reference module (Filipovich et al. 2005; Przepiorka et al. 1995).

groups

description
Donor lymphocyte preparation depleted of host functional alloreactive T-cells: Single intravenous infusion with 2x10E6 T-cells/kg
id
OG000
title
ATIR

param Type

NUMBER

reporting Status

POSTED

time Frame

Up to 24 months after the transplantation

title

Incidence and Severity Graft-versus-host Disease (GVHD)

type

SECONDARY

unit Of Measure

Percentage of participants

Download exact source JSON → · Snapshot ctgov-results-25a395029948b04d52b1253f

Preserved source evidence · Not medical advice