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NCT00753688 · BASELINE

Baseline characteristics

Pazopanib Versus Placebo in Patients With Soft Tissue Sarcoma Whose Disease Has Progressed During or Following Prior Therapy · Source last updated 2013-08-22

Results reported by the registry submitting party. Population, time horizon, units and missing values must be read together.

denoms
  1. counts
    1. group Id
      BG000
      value
      123
    2. group Id
      BG001
      value
      246
    3. group Id
      BG002
      value
      369
    units
    Participants
groups
  1. description
    Matching placebo tablets administered orally once daily for a duration until participants experienced disease progression, death, unacceptable toxicity, or participants withdrew consent
    id
    BG000
    title
    Placebo
  2. description
    Pazopanib 200 milligrams (mg) and 400 mg film-coated tablets (containing pazopanib monohydrochloride) administered orally at a dose of 800 mg once daily for a duration until participants experienced disease progression, death, unacceptable toxicity, or participants withdrew consent
    id
    BG001
    title
    Pazopanib
  3. description
    Total of all reporting groups
    id
    BG002
    title
    Total
measures
  1. classes
    1. categories
      1. measurements
        1. group Id
          BG000
          spread
          13.77
          value
          51.7
        2. group Id
          BG001
          spread
          14.92
          value
          54.0
        3. group Id
          BG002
          spread
          14.57
          value
          53.2
    dispersion Type
    STANDARD_DEVIATION
    param Type
    MEAN
    title
    Age Continuous
    unit Of Measure
    Years
  2. classes
    1. categories
      1. measurements
        1. group Id
          BG000
          value
          69
        2. group Id
          BG001
          value
          147
        3. group Id
          BG002
          value
          216
        title
        Female
      2. measurements
        1. group Id
          BG000
          value
          54
        2. group Id
          BG001
          value
          99
        3. group Id
          BG002
          value
          153
        title
        Male
    param Type
    COUNT_OF_PARTICIPANTS
    title
    Sex: Female, Male
    unit Of Measure
    Participants
  3. classes
    1. categories
      1. measurements
        1. group Id
          BG000
          value
          2
        2. group Id
          BG001
          value
          4
        3. group Id
          BG002
          value
          6
      title
      African American/African Heritage
    2. categories
      1. measurements
        1. group Id
          BG000
          value
          0
        2. group Id
          BG001
          value
          1
        3. group Id
          BG002
          value
          1
      title
      American Indian or Alaska Native
    3. categories
      1. measurements
        1. group Id
          BG000
          value
          2
        2. group Id
          BG001
          value
          0
        3. group Id
          BG002
          value
          2
      title
      Asian - Central/South Asian Heritage
    4. categories
      1. measurements
        1. group Id
          BG000
          value
          7
        2. group Id
          BG001
          value
          24
        3. group Id
          BG002
          value
          31
      title
      Asian - East Asian Heritage
    5. categories
      1. measurements
        1. group Id
          BG000
          value
          16
        2. group Id
          BG001
          value
          31
        3. group Id
          BG002
          value
          47
      title
      Asian - Japanese Heritage
    6. categories
      1. measurements
        1. group Id
          BG000
          value
          2
        2. group Id
          BG001
          value
          2
        3. group Id
          BG002
          value
          4
      title
      Asian - South East Asian Heritage
    7. categories
      1. measurements
        1. group Id
          BG000
          value
          2
        2. group Id
          BG001
          value
          1
        3. group Id
          BG002
          value
          3
      title
      White - Arabic/North African Heritage
    8. categories
      1. measurements
        1. group Id
          BG000
          value
          89
        2. group Id
          BG001
          value
          174
        3. group Id
          BG002
          value
          263
      title
      White - White/Caucasian/European Heritage
    9. categories
      1. measurements
        1. group Id
          BG000
          value
          1
        2. group Id
          BG001
          value
          0
        3. group Id
          BG002
          value
          1
      title
      Mixed Race
    10. categories
      1. measurements
        1. group Id
          BG000
          value
          2
        2. group Id
          BG001
          value
          9
        3. group Id
          BG002
          value
          11
      title
      Unknown
    param Type
    NUMBER
    title
    Race/Ethnicity, Customized
    unit Of Measure
    participants
  4. classes
    1. categories
      1. measurements
        1. group Id
          BG000
          value
          49
        2. group Id
          BG001
          value
          109
        3. group Id
          BG002
          value
          158
      title
      Leiomyosarcoma
    2. categories
      1. measurements
        1. group Id
          BG000
          value
          13
        2. group Id
          BG001
          value
          25
        3. group Id
          BG002
          value
          38
      title
      Synovial sarcoma
    3. categories
      1. measurements
        1. group Id
          BG000
          value
          61
        2. group Id
          BG001
          value
          112
        3. group Id
          BG002
          value
          173
      title
      Other STS histologies
    description
    Participants were categorized in the following histology subgroups of STS (as per the World Health Organization \[WHO\] classification, 2008): leiomyosarcoma, defined as malignant cancer of smooth muscle; synovial sarcoma, defined as cancer near the joints of the arm or leg; and other STS, defined as sarcoma without the tumor type of leiomyosarcoma or synovial sarcoma.
    param Type
    NUMBER
    title
    Number of participants in the indicated soft tissue sarcoma (STS) subgroups at Baseline
    unit Of Measure
    participants
Complete source fields
denoms
  1. counts
    1. group Id
      BG000
      value
      123
    2. group Id
      BG001
      value
      246
    3. group Id
      BG002
      value
      369
    units
    Participants
groups
  1. description
    Matching placebo tablets administered orally once daily for a duration until participants experienced disease progression, death, unacceptable toxicity, or participants withdrew consent
    id
    BG000
    title
    Placebo
  2. description
    Pazopanib 200 milligrams (mg) and 400 mg film-coated tablets (containing pazopanib monohydrochloride) administered orally at a dose of 800 mg once daily for a duration until participants experienced disease progression, death, unacceptable toxicity, or participants withdrew consent
    id
    BG001
    title
    Pazopanib
  3. description
    Total of all reporting groups
    id
    BG002
    title
    Total
measures
  1. classes
    1. categories
      1. measurements
        1. group Id
          BG000
          spread
          13.77
          value
          51.7
        2. group Id
          BG001
          spread
          14.92
          value
          54.0
        3. group Id
          BG002
          spread
          14.57
          value
          53.2
    dispersion Type
    STANDARD_DEVIATION
    param Type
    MEAN
    title
    Age Continuous
    unit Of Measure
    Years
  2. classes
    1. categories
      1. measurements
        1. group Id
          BG000
          value
          69
        2. group Id
          BG001
          value
          147
        3. group Id
          BG002
          value
          216
        title
        Female
      2. measurements
        1. group Id
          BG000
          value
          54
        2. group Id
          BG001
          value
          99
        3. group Id
          BG002
          value
          153
        title
        Male
    param Type
    COUNT_OF_PARTICIPANTS
    title
    Sex: Female, Male
    unit Of Measure
    Participants
  3. classes
    1. categories
      1. measurements
        1. group Id
          BG000
          value
          2
        2. group Id
          BG001
          value
          4
        3. group Id
          BG002
          value
          6
      title
      African American/African Heritage
    2. categories
      1. measurements
        1. group Id
          BG000
          value
          0
        2. group Id
          BG001
          value
          1
        3. group Id
          BG002
          value
          1
      title
      American Indian or Alaska Native
    3. categories
      1. measurements
        1. group Id
          BG000
          value
          2
        2. group Id
          BG001
          value
          0
        3. group Id
          BG002
          value
          2
      title
      Asian - Central/South Asian Heritage
    4. categories
      1. measurements
        1. group Id
          BG000
          value
          7
        2. group Id
          BG001
          value
          24
        3. group Id
          BG002
          value
          31
      title
      Asian - East Asian Heritage
    5. categories
      1. measurements
        1. group Id
          BG000
          value
          16
        2. group Id
          BG001
          value
          31
        3. group Id
          BG002
          value
          47
      title
      Asian - Japanese Heritage
    6. categories
      1. measurements
        1. group Id
          BG000
          value
          2
        2. group Id
          BG001
          value
          2
        3. group Id
          BG002
          value
          4
      title
      Asian - South East Asian Heritage
    7. categories
      1. measurements
        1. group Id
          BG000
          value
          2
        2. group Id
          BG001
          value
          1
        3. group Id
          BG002
          value
          3
      title
      White - Arabic/North African Heritage
    8. categories
      1. measurements
        1. group Id
          BG000
          value
          89
        2. group Id
          BG001
          value
          174
        3. group Id
          BG002
          value
          263
      title
      White - White/Caucasian/European Heritage
    9. categories
      1. measurements
        1. group Id
          BG000
          value
          1
        2. group Id
          BG001
          value
          0
        3. group Id
          BG002
          value
          1
      title
      Mixed Race
    10. categories
      1. measurements
        1. group Id
          BG000
          value
          2
        2. group Id
          BG001
          value
          9
        3. group Id
          BG002
          value
          11
      title
      Unknown
    param Type
    NUMBER
    title
    Race/Ethnicity, Customized
    unit Of Measure
    participants
  4. classes
    1. categories
      1. measurements
        1. group Id
          BG000
          value
          49
        2. group Id
          BG001
          value
          109
        3. group Id
          BG002
          value
          158
      title
      Leiomyosarcoma
    2. categories
      1. measurements
        1. group Id
          BG000
          value
          13
        2. group Id
          BG001
          value
          25
        3. group Id
          BG002
          value
          38
      title
      Synovial sarcoma
    3. categories
      1. measurements
        1. group Id
          BG000
          value
          61
        2. group Id
          BG001
          value
          112
        3. group Id
          BG002
          value
          173
      title
      Other STS histologies
    description
    Participants were categorized in the following histology subgroups of STS (as per the World Health Organization \[WHO\] classification, 2008): leiomyosarcoma, defined as malignant cancer of smooth muscle; synovial sarcoma, defined as cancer near the joints of the arm or leg; and other STS, defined as sarcoma without the tumor type of leiomyosarcoma or synovial sarcoma.
    param Type
    NUMBER
    title
    Number of participants in the indicated soft tissue sarcoma (STS) subgroups at Baseline
    unit Of Measure
    participants

Download exact source JSON → · Snapshot ctgov-results-191f4516d4760045304b24a0

Preserved source evidence · Not medical advice