TriangleNCT00721123 · OUTCOME
Percentage of Participants Classified as Responders by Disease Activity Scores Over Time, Through 264 Weeks
Results reported by the registry submitting party. Population, time horizon, units and missing values must be read together.
- Measure
- NUMBER
- Unit
- Percentage of Participants
- Interval / dispersion
- Not reported
- Time frame
- through 264 Weeks
What was measured
The disease activity score 28 (DAS28) is a combined index for measuring disease activity in rheumatic arthritis (RA) that includes swollen and tender joint counts, erythrocyte sedimentation rate (ESR), and general health (GH) status. The DAS28 scale ranges from 0 to 10, where lower scores represent less disease activity. Participants with DAS28 scores less than 2.6 were categorized as responders with remission and those with DAS 28 scores of 3.2 or less were categorized as responders with low disease activity (LDA). The percentage of participants classified as responders in each category was recorded over time.
Analysis population: All exposure population, which includes all participants who entered the study and received at least one dose of tocilizumab at any time.
Groups in this outcome
Week 24
Participants with scores at 24 weeks post-baseline.
Week 48
Participants with scores at 48 weeks post-baseline.
Week 108
Participants with scores at 108 weeks post-baseline.
Week 156
Participants with scores at 156 weeks post-baseline.
Week 204
Participants with scores at 204 weeks post-baseline.
Week 264
Participants with scores at 264 weeks post-baseline.
| Group | Source count |
|---|---|
| Week 24 | 516 |
| Week 48 | 470 |
| Week 108 | 430 |
| Week 156 | 410 |
| Week 204 | 381 |
| Week 264 | 363 |
Reported measurements
Responders with Remission (DAS<2.6)
| Group | Value | Spread | Lower | Upper | Comment |
|---|---|---|---|---|---|
| Week 24 | 24.6 | Not reported | Not reported | Not reported | Not reported |
| Week 48 | 43.0 | Not reported | Not reported | Not reported | Not reported |
| Week 108 | 53.7 | Not reported | Not reported | Not reported | Not reported |
| Week 156 | 54.9 | Not reported | Not reported | Not reported | Not reported |
| Week 204 | 57.2 | Not reported | Not reported | Not reported | Not reported |
| Week 264 | 60.6 | Not reported | Not reported | Not reported | Not reported |
Responders with Low Disease Activity (DAS</= 3.2)
| Group | Value | Spread | Lower | Upper | Comment |
|---|---|---|---|---|---|
| Week 24 | 41.7 | Not reported | Not reported | Not reported | Not reported |
| Week 48 | 57.7 | Not reported | Not reported | Not reported | Not reported |
| Week 108 | 67.0 | Not reported | Not reported | Not reported | Not reported |
| Week 156 | 71.2 | Not reported | Not reported | Not reported | Not reported |
| Week 204 | 70.6 | Not reported | Not reported | Not reported | Not reported |
| Week 264 | 72.2 | Not reported | Not reported | Not reported | Not reported |
Complete source fields
- classes
- categories
- measurements
- group Id
- OG000
- value
- 24.6
- group Id
- OG001
- value
- 43.0
- group Id
- OG002
- value
- 53.7
- group Id
- OG003
- value
- 54.9
- group Id
- OG004
- value
- 57.2
- group Id
- OG005
- value
- 60.6
- title
- Responders with Remission (DAS<2.6)
- categories
- measurements
- group Id
- OG000
- value
- 41.7
- group Id
- OG001
- value
- 57.7
- group Id
- OG002
- value
- 67.0
- group Id
- OG003
- value
- 71.2
- group Id
- OG004
- value
- 70.6
- group Id
- OG005
- value
- 72.2
- title
- Responders with Low Disease Activity (DAS</= 3.2)
- denoms
- counts
- group Id
- OG000
- value
- 516
- group Id
- OG001
- value
- 470
- group Id
- OG002
- value
- 430
- group Id
- OG003
- value
- 410
- group Id
- OG004
- value
- 381
- group Id
- OG005
- value
- 363
- units
- Participants
- description
- The disease activity score 28 (DAS28) is a combined index for measuring disease activity in rheumatic arthritis (RA) that includes swollen and tender joint counts, erythrocyte sedimentation rate (ESR), and general health (GH) status. The DAS28 scale ranges from 0 to 10, where lower scores represent less disease activity. Participants with DAS28 scores less than 2.6 were categorized as responders with remission and those with DAS 28 scores of 3.2 or less were categorized as responders with low disease activity (LDA). The percentage of participants classified as responders in each category was recorded over time.
- groups
- description
- Participants with scores at 24 weeks post-baseline.
- id
- OG000
- title
- Week 24
- description
- Participants with scores at 48 weeks post-baseline.
- id
- OG001
- title
- Week 48
- description
- Participants with scores at 108 weeks post-baseline.
- id
- OG002
- title
- Week 108
- description
- Participants with scores at 156 weeks post-baseline.
- id
- OG003
- title
- Week 156
- description
- Participants with scores at 204 weeks post-baseline.
- id
- OG004
- title
- Week 204
- description
- Participants with scores at 264 weeks post-baseline.
- id
- OG005
- title
- Week 264
- param Type
- NUMBER
- population Description
- All exposure population, which includes all participants who entered the study and received at least one dose of tocilizumab at any time.
- reporting Status
- POSTED
- time Frame
- through 264 Weeks
- title
- Percentage of Participants Classified as Responders by Disease Activity Scores Over Time, Through 264 Weeks
- type
- SECONDARY
- unit Of Measure
- Percentage of Participants
Download exact source JSON → · Snapshot ctgov-results-25a395029948b04d52b1253f
Preserved source evidence · Not medical advice