NCT00716976 · OUTCOME

Change in Hearing Thresholds For Key Frequencies at 500 hz

Sodium Thiosulfate in Preventing Hearing Loss in Young Patients Receiving Cisplatin for Newly Diagnosed Germ Cell Tumor, Hepatoblastoma, Medulloblastoma, Neuroblastoma, Osteosarcoma, or Other Malignancy · Source last updated 2023-11-09

Results reported by the registry submitting party. Population, time horizon, units and missing values must be read together.

Measure: MEAN
Unit: Decibels
Interval / dispersion: Standard Deviation
Time frame: 4 weeks after last dose of cisplatin

What was measured

Mean change in hearing threshold (post-pre) at 500 hz.

Analysis population: 38 eligible patients in the STS arm had paired audiometry at 500 hz; 45 patients in the observation arm had paired audiometry at 500 hz.

Groups in this outcome

STS Arm (Sodium Thiosulfate Treatment)

Sodium thiosulfate treatment.

Observation Arm

No sodium thiosulfate treatment.

Group identifiers and denominators belong to this outcome only. They may differ in another outcome or in safety reporting.

Analysis denominator · Participants

Group	Source count
STS Arm (Sodium Thiosulfate Treatment)	38
Observation Arm	45

Reported measurements

Source class 1

Values in Decibels · Interval/dispersion: Standard Deviation
Group	Value	Spread	Lower	Upper	Comment
STS Arm (Sodium Thiosulfate Treatment)	-1.45	5.80	Not reported	Not reported	Not reported
Observation Arm	-1.11	8.59	Not reported	Not reported	Not reported

Complete source fields

classes

categories
measurements
group Id
OG000
spread
5.80
value
-1.45
group Id
OG001
spread
8.59
value
-1.11

denoms

counts
group Id
OG000
value
38
group Id
OG001
value
45
units
Participants

description

Mean change in hearing threshold (post-pre) at 500 hz.

dispersion Type

Standard Deviation

groups

description
Sodium thiosulfate treatment.
id
OG000
title
STS Arm (Sodium Thiosulfate Treatment)
description
No sodium thiosulfate treatment.
id
OG001
title
Observation Arm

param Type

MEAN

population Description

38 eligible patients in the STS arm had paired audiometry at 500 hz; 45 patients in the observation arm had paired audiometry at 500 hz.

reporting Status

POSTED

time Frame

4 weeks after last dose of cisplatin

title

Change in Hearing Thresholds For Key Frequencies at 500 hz

type

SECONDARY

unit Of Measure

Decibels

Download exact source JSON → · Snapshot ctgov-results-191f4516d4760045304b24a0

Preserved source evidence · Not medical advice