Skip to content
Triangle logo TriangleGet started
← Full study record

NCT00701103 · BASELINE

Baseline characteristics

Dose Escalation Trial of Dalotuzumab (MK-0646) in Advanced Solid Tumors and Multiple Myeloma (MK-0646-001) · Source last updated 2018-08-08

Results reported by the registry submitting party. Population, time horizon, units and missing values must be read together.

denoms
  1. counts
    1. group Id
      BG000
      value
      5
    2. group Id
      BG001
      value
      3
    3. group Id
      BG002
      value
      8
    4. group Id
      BG003
      value
      6
    5. group Id
      BG004
      value
      6
    6. group Id
      BG005
      value
      6
    7. group Id
      BG006
      value
      8
    8. group Id
      BG007
      value
      7
    9. group Id
      BG008
      value
      9
    10. group Id
      BG009
      value
      11
    11. group Id
      BG010
      value
      11
    12. group Id
      BG011
      value
      80
    units
    Participants
groups
  1. description
    Participants received dalotuzumab 1.25 mg/kg (10 mg/mL) IV infusion Q1W.
    id
    BG000
    title
    Dalotuzumab 1.25 mg/kg Q1W (10 mg/mL)
  2. description
    Participants received dalotuzumab 2.5 mg/kg (10 mg/mL) IV infusion Q1W.
    id
    BG001
    title
    Dalotuzumab 2.5 mg/kg Q1W (10 mg/mL)
  3. description
    Participants received dalotuzumab 5 mg/kg (10 mg/mL) IV infusion Q1W.
    id
    BG002
    title
    Dalotuzumab 5 mg/kg Q1W (10 mg/mL)
  4. description
    Participants received dalotuzumab 10 mg/kg (10 mg/mL) IV infusion Q1W.
    id
    BG003
    title
    Dalotuzumab 10 mg/kg Q1W (10 mg/mL)
  5. description
    Participants received dalotuzumab 10 mg/kg (20 mg/mL) IV infusion Q1W.
    id
    BG004
    title
    Dalotuzumab 10 mg/kg Q1W (20 mg/mL)
  6. description
    Participants received dalotuzumab 15 mg/kg (10 mg/mL) IV infusion Q1W.
    id
    BG005
    title
    Dalotuzumab 15 mg/kg Q1W (10 mg/mL)
  7. description
    Participants received dalotuzumab 15 mg/kg (20 mg/ mL) IV infusion Q1W.
    id
    BG006
    title
    Dalotuzumab 15 mg/kg Q1W (20 mg/mL)
  8. description
    Participants received dalotuzumab 20 mg/kg (10 mg/mL) IV infusion Q1W.
    id
    BG007
    title
    Dalotuzumab 20 mg/kg Q1W (10 mg/mL)
  9. description
    Participants received dalotuzumab 20.0 mg/kg (20 mg/mL) IV infusion Q1W.
    id
    BG008
    title
    Dalotuzumab 20 mg/kg Q1W (20 mg/mL)
  10. description
    Participants received dalotuzumab 20 mg/kg (20 mg/mL) IV infusion Q2W.
    id
    BG009
    title
    Dalotuzumab 20 mg/kg Q2W (20 mg/mL)
  11. description
    Participants received dalotuzumab 30 mg/kg (20 mg/mL) IV infusion Q3W.
    id
    BG010
    title
    Dalotuzumab 30 mg/kg Q3W (20 mg/mL)
  12. description
    Total of all reporting groups
    id
    BG011
    title
    Total
measures
  1. classes
    1. categories
      1. measurements
        1. group Id
          BG000
          lower Limit
          59
          spread
          9
          upper Limit
          81
          value
          69
        2. group Id
          BG001
          lower Limit
          50
          spread
          9
          upper Limit
          68
          value
          60
        3. group Id
          BG002
          lower Limit
          51
          spread
          9
          upper Limit
          80
          value
          68
        4. group Id
          BG003
          lower Limit
          40
          spread
          10
          upper Limit
          68
          value
          56
        5. group Id
          BG004
          lower Limit
          26
          spread
          17
          upper Limit
          70
          value
          53
        6. group Id
          BG005
          lower Limit
          23
          spread
          22
          upper Limit
          70
          value
          49
        7. group Id
          BG006
          lower Limit
          29
          spread
          18
          upper Limit
          64
          value
          54
        8. group Id
          BG007
          lower Limit
          27
          spread
          13
          upper Limit
          78
          value
          46
        9. group Id
          BG008
          lower Limit
          22
          spread
          18
          upper Limit
          69
          value
          52
        10. group Id
          BG009
          lower Limit
          23
          spread
          17
          upper Limit
          77
          value
          55
        11. group Id
          BG010
          lower Limit
          19
          spread
          15
          upper Limit
          73
          value
          52
        12. group Id
          BG011
          lower Limit
          19
          spread
          16
          upper Limit
          81
          value
          55
    dispersion Type
    STANDARD_DEVIATION
    param Type
    MEAN
    title
    Age, Continuous
    unit Of Measure
    Years
  2. classes
    1. categories
      1. measurements
        1. group Id
          BG000
          value
          1
        2. group Id
          BG001
          value
          1
        3. group Id
          BG002
          value
          4
        4. group Id
          BG003
          value
          6
        5. group Id
          BG004
          value
          3
        6. group Id
          BG005
          value
          3
        7. group Id
          BG006
          value
          4
        8. group Id
          BG007
          value
          2
        9. group Id
          BG008
          value
          5
        10. group Id
          BG009
          value
          5
        11. group Id
          BG010
          value
          6
        12. group Id
          BG011
          value
          40
        title
        Female
      2. measurements
        1. group Id
          BG000
          value
          4
        2. group Id
          BG001
          value
          2
        3. group Id
          BG002
          value
          4
        4. group Id
          BG003
          value
          0
        5. group Id
          BG004
          value
          3
        6. group Id
          BG005
          value
          3
        7. group Id
          BG006
          value
          4
        8. group Id
          BG007
          value
          5
        9. group Id
          BG008
          value
          4
        10. group Id
          BG009
          value
          6
        11. group Id
          BG010
          value
          5
        12. group Id
          BG011
          value
          40
        title
        Male
    param Type
    COUNT_OF_PARTICIPANTS
    title
    Sex: Female, Male
    unit Of Measure
    Participants
population Description
The population consisted of all participants who received at least one dose of study drug.
Complete source fields
denoms
  1. counts
    1. group Id
      BG000
      value
      5
    2. group Id
      BG001
      value
      3
    3. group Id
      BG002
      value
      8
    4. group Id
      BG003
      value
      6
    5. group Id
      BG004
      value
      6
    6. group Id
      BG005
      value
      6
    7. group Id
      BG006
      value
      8
    8. group Id
      BG007
      value
      7
    9. group Id
      BG008
      value
      9
    10. group Id
      BG009
      value
      11
    11. group Id
      BG010
      value
      11
    12. group Id
      BG011
      value
      80
    units
    Participants
groups
  1. description
    Participants received dalotuzumab 1.25 mg/kg (10 mg/mL) IV infusion Q1W.
    id
    BG000
    title
    Dalotuzumab 1.25 mg/kg Q1W (10 mg/mL)
  2. description
    Participants received dalotuzumab 2.5 mg/kg (10 mg/mL) IV infusion Q1W.
    id
    BG001
    title
    Dalotuzumab 2.5 mg/kg Q1W (10 mg/mL)
  3. description
    Participants received dalotuzumab 5 mg/kg (10 mg/mL) IV infusion Q1W.
    id
    BG002
    title
    Dalotuzumab 5 mg/kg Q1W (10 mg/mL)
  4. description
    Participants received dalotuzumab 10 mg/kg (10 mg/mL) IV infusion Q1W.
    id
    BG003
    title
    Dalotuzumab 10 mg/kg Q1W (10 mg/mL)
  5. description
    Participants received dalotuzumab 10 mg/kg (20 mg/mL) IV infusion Q1W.
    id
    BG004
    title
    Dalotuzumab 10 mg/kg Q1W (20 mg/mL)
  6. description
    Participants received dalotuzumab 15 mg/kg (10 mg/mL) IV infusion Q1W.
    id
    BG005
    title
    Dalotuzumab 15 mg/kg Q1W (10 mg/mL)
  7. description
    Participants received dalotuzumab 15 mg/kg (20 mg/ mL) IV infusion Q1W.
    id
    BG006
    title
    Dalotuzumab 15 mg/kg Q1W (20 mg/mL)
  8. description
    Participants received dalotuzumab 20 mg/kg (10 mg/mL) IV infusion Q1W.
    id
    BG007
    title
    Dalotuzumab 20 mg/kg Q1W (10 mg/mL)
  9. description
    Participants received dalotuzumab 20.0 mg/kg (20 mg/mL) IV infusion Q1W.
    id
    BG008
    title
    Dalotuzumab 20 mg/kg Q1W (20 mg/mL)
  10. description
    Participants received dalotuzumab 20 mg/kg (20 mg/mL) IV infusion Q2W.
    id
    BG009
    title
    Dalotuzumab 20 mg/kg Q2W (20 mg/mL)
  11. description
    Participants received dalotuzumab 30 mg/kg (20 mg/mL) IV infusion Q3W.
    id
    BG010
    title
    Dalotuzumab 30 mg/kg Q3W (20 mg/mL)
  12. description
    Total of all reporting groups
    id
    BG011
    title
    Total
measures
  1. classes
    1. categories
      1. measurements
        1. group Id
          BG000
          lower Limit
          59
          spread
          9
          upper Limit
          81
          value
          69
        2. group Id
          BG001
          lower Limit
          50
          spread
          9
          upper Limit
          68
          value
          60
        3. group Id
          BG002
          lower Limit
          51
          spread
          9
          upper Limit
          80
          value
          68
        4. group Id
          BG003
          lower Limit
          40
          spread
          10
          upper Limit
          68
          value
          56
        5. group Id
          BG004
          lower Limit
          26
          spread
          17
          upper Limit
          70
          value
          53
        6. group Id
          BG005
          lower Limit
          23
          spread
          22
          upper Limit
          70
          value
          49
        7. group Id
          BG006
          lower Limit
          29
          spread
          18
          upper Limit
          64
          value
          54
        8. group Id
          BG007
          lower Limit
          27
          spread
          13
          upper Limit
          78
          value
          46
        9. group Id
          BG008
          lower Limit
          22
          spread
          18
          upper Limit
          69
          value
          52
        10. group Id
          BG009
          lower Limit
          23
          spread
          17
          upper Limit
          77
          value
          55
        11. group Id
          BG010
          lower Limit
          19
          spread
          15
          upper Limit
          73
          value
          52
        12. group Id
          BG011
          lower Limit
          19
          spread
          16
          upper Limit
          81
          value
          55
    dispersion Type
    STANDARD_DEVIATION
    param Type
    MEAN
    title
    Age, Continuous
    unit Of Measure
    Years
  2. classes
    1. categories
      1. measurements
        1. group Id
          BG000
          value
          1
        2. group Id
          BG001
          value
          1
        3. group Id
          BG002
          value
          4
        4. group Id
          BG003
          value
          6
        5. group Id
          BG004
          value
          3
        6. group Id
          BG005
          value
          3
        7. group Id
          BG006
          value
          4
        8. group Id
          BG007
          value
          2
        9. group Id
          BG008
          value
          5
        10. group Id
          BG009
          value
          5
        11. group Id
          BG010
          value
          6
        12. group Id
          BG011
          value
          40
        title
        Female
      2. measurements
        1. group Id
          BG000
          value
          4
        2. group Id
          BG001
          value
          2
        3. group Id
          BG002
          value
          4
        4. group Id
          BG003
          value
          0
        5. group Id
          BG004
          value
          3
        6. group Id
          BG005
          value
          3
        7. group Id
          BG006
          value
          4
        8. group Id
          BG007
          value
          5
        9. group Id
          BG008
          value
          4
        10. group Id
          BG009
          value
          6
        11. group Id
          BG010
          value
          5
        12. group Id
          BG011
          value
          40
        title
        Male
    param Type
    COUNT_OF_PARTICIPANTS
    title
    Sex: Female, Male
    unit Of Measure
    Participants
population Description
The population consisted of all participants who received at least one dose of study drug.

Download exact source JSON → · Snapshot ctgov-results-25a395029948b04d52b1253f

Preserved source evidence · Not medical advice