Baseline characteristics

Dose-finding Study Comparing Efficacy and Safety of a PARP Inhibitor Against Doxil in BRCA+ve Advanced Ovarian Cancer · Source last updated 2019-12-05

Results reported by the registry submitting party. Population, time horizon, units and missing values must be read together.

denoms

1. counts

   1. group Id

      BG000

      value

      32

   2. group Id

      BG001

      value

      32

   3. group Id

      BG002

      value

      33

   4. group Id

      BG003

      value

      97

   units

   Participants

groups

1. description

   Olaparib (AZD2281) 200 mg oral capsules twice daily

   id

   BG000

   title

   Olaparib 200 mg bd

2. description

   Olaparib (AZD2281) 400 mg oral capsules twice daily

   id

   BG001

   title

   Olaparib 400 mg bd

3. description

   Liposomal doxorubicin 50 mg/m2 intravenously every 4 weeks

   id

   BG002

   title

   Liposomal Doxorubicin

4. description

   Total of all reporting groups

   id

   BG003

   title

   Total

measures

1. classes

   1. categories

      1. measurements

         1. group Id

            BG000

            spread

            8.53

            value

            57.2

         2. group Id

            BG001

            spread

            8.77

            value

            53.8

         3. group Id

            BG002

            spread

            9.32

            value

            54.3

         4. group Id

            BG003

            spread

            8.92

            value

            55.5

   dispersion Type

   STANDARD_DEVIATION

   param Type

   MEAN

   title

   Age, Continuous

   unit Of Measure

   Years

2. classes

   1. categories

      1. measurements

         1. group Id

            BG000

            value

            32

         2. group Id

            BG001

            value

            32

         3. group Id

            BG002

            value

            33

         4. group Id

            BG003

            value

            97

         title

         Female

      2. measurements

         1. group Id

            BG000

            value

            0

         2. group Id

            BG001

            value

            0

         3. group Id

            BG002

            value

            0

         4. group Id

            BG003

            value

            0

         title

         Male

   param Type

   COUNT_OF_PARTICIPANTS

   title

   Sex: Female, Male

   unit Of Measure

   Participants

3. classes

   1. categories

      1. measurements

         1. group Id

            BG000

            value

            0

         2. group Id

            BG001

            value

            0

         3. group Id

            BG002

            value

            1

         4. group Id

            BG003

            value

            1

      title

      African-Caribbean

   2. categories

      1. measurements

         1. group Id

            BG000

            value

            8

         2. group Id

            BG001

            value

            10

         3. group Id

            BG002

            value

            11

         4. group Id

            BG003

            value

            29

      title

      Ashkenazi Jewish

   3. categories

      1. measurements

         1. group Id

            BG000

            value

            0

         2. group Id

            BG001

            value

            0

         3. group Id

            BG002

            value

            2

         4. group Id

            BG003

            value

            2

      title

      Sephardic Jewish

   4. categories

      1. measurements

         1. group Id

            BG000

            value

            20

         2. group Id

            BG001

            value

            21

         3. group Id

            BG002

            value

            19

         4. group Id

            BG003

            value

            60

      title

      Not applicable

   5. categories

      1. measurements

         1. group Id

            BG000

            value

            4

         2. group Id

            BG001

            value

            1

         3. group Id

            BG002

            value

            0

         4. group Id

            BG003

            value

            5

      title

      Other

   description

   Race/Ethnicity (Jewish ethnicity)

   param Type

   NUMBER

   title

   Race/Ethnicity, Customized

   unit Of Measure

   Participants

4. classes

   1. categories

      1. measurements

         1. group Id

            BG000

            value

            26

         2. group Id

            BG001

            value

            28

         3. group Id

            BG002

            value

            27

         4. group Id

            BG003

            value

            81

      title

      Deleterious BRCA1 mutation

   2. categories

      1. measurements

         1. group Id

            BG000

            value

            6

         2. group Id

            BG001

            value

            4

         3. group Id

            BG002

            value

            6

         4. group Id

            BG003

            value

            16

      title

      Deleterious BRCA2 mutation

   param Type

   NUMBER

   title

   BRCA status

   unit Of Measure

   Participants

Download exact source JSON → · Snapshot ctgov-results-191f4516d4760045304b24a0

Preserved source evidence · Not medical advice