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NCT00627393 · OUTCOME

Evaluation of Granulocyte Yield

Safety and Effectiveness of Granulocyte Transfusions in Resolving Infection in People With Neutropenia (The RING Study) · Source last updated 2015-04-17

Results reported by the registry submitting party. Population, time horizon, units and missing values must be read together.

Measure
MEDIAN
Unit
Granulocyte Yield (billion cells/liter)
Interval / dispersion
Inter-Quartile Range
Time frame
Measured immediately after each granulocyte donation

Groups in this outcome

Granulocyte Donors

Participants will donate granulocytes after receiving a combination of two drugs, G-CSF and dexamethasone G-CSF/dexamethasone: Twelve hours before each donation, participants will be injected with G-CSF and will take one dose of dexamethasone by mouth. Apheresis machine: Participants will undergo a procedure using an apheresis machine for granulocyte collection. The procedure will last 3 to 4 hours and will involve the drawing of blood from each arm, the separation of granulocytes from the red cells and plasma in the machine, and the return of the red cells and plasma to the participants.

Group identifiers and denominators belong to this outcome only. They may differ in another outcome or in safety reporting.

Analysis denominator · Participants

GroupSource count
Granulocyte Donors237

Analysis denominator · Granulocyte Donations

GroupSource count
Granulocyte Donors340

Reported measurements

Source class 1
Values in Granulocyte Yield (billion cells/liter) · Interval/dispersion: Inter-Quartile Range
GroupValueSpreadLowerUpperComment
Granulocyte Donors174.75Not reported89.76242.41Not reported
Complete source fields
classes
  1. categories
    1. measurements
      1. group Id
        OG000
        lower Limit
        89.76
        upper Limit
        242.41
        value
        174.75
denom Units Selected
Participants
denoms
  1. counts
    1. group Id
      OG000
      value
      237
    units
    Participants
  2. counts
    1. group Id
      OG000
      value
      340
    units
    Granulocyte Donations
dispersion Type
Inter-Quartile Range
groups
  1. description
    Participants will donate granulocytes after receiving a combination of two drugs, G-CSF and dexamethasone G-CSF/dexamethasone: Twelve hours before each donation, participants will be injected with G-CSF and will take one dose of dexamethasone by mouth. Apheresis machine: Participants will undergo a procedure using an apheresis machine for granulocyte collection. The procedure will last 3 to 4 hours and will involve the drawing of blood from each arm, the separation of granulocytes from the red cells and plasma in the machine, and the return of the red cells and plasma to the participants.
    id
    OG000
    title
    Granulocyte Donors
param Type
MEDIAN
reporting Status
POSTED
time Frame
Measured immediately after each granulocyte donation
title
Evaluation of Granulocyte Yield
type
SECONDARY
type Units Analyzed
Granulocyte Donations
unit Of Measure
Granulocyte Yield (billion cells/liter)

Download exact source JSON → · Snapshot ctgov-results-191f4516d4760045304b24a0

Preserved source evidence · Not medical advice