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NCT00602667 · OUTCOME

Pharmacogenetic Variation on Central Nervous System Transmitters

Risk-Adapted Therapy for Young Children With Embryonal Brain Tumors, Choroid Plexus Carcinoma, High Grade Glioma or Ependymoma · Source last updated 2026-05-19

Results reported by the registry submitting party. Population, time horizon, units and missing values must be read together.

Measure
COUNT_OF_PARTICIPANTS
Unit
Participants
Interval / dispersion
Not reported
Time frame
At study enrollment (Day 0)

What was measured

Frequencies of genetic polymorphisms were reported.

Analysis population: Eligible patients who had neurotransmitter studies performed. Seventeen patients had studies performed.

Groups in this outcome

Patients With Neurotransmitter Studies

Patients with neurotransmitter studies

Group identifiers and denominators belong to this outcome only. They may differ in another outcome or in safety reporting.

Analysis denominator · Participants

GroupSource count
Patients With Neurotransmitter Studies17

Reported measurements

Genetic Polymorphisms for monoamine oxidase A (MAOA) rs6323

AA

Values in Participants · Interval/dispersion: Not reported
GroupValueSpreadLowerUpperComment
Patients With Neurotransmitter Studies0Not reportedNot reportedNot reportedNot reported

AG

Values in Participants · Interval/dispersion: Not reported
GroupValueSpreadLowerUpperComment
Patients With Neurotransmitter Studies0Not reportedNot reportedNot reportedNot reported

CC

Values in Participants · Interval/dispersion: Not reported
GroupValueSpreadLowerUpperComment
Patients With Neurotransmitter Studies0Not reportedNot reportedNot reportedNot reported

GG

Values in Participants · Interval/dispersion: Not reported
GroupValueSpreadLowerUpperComment
Patients With Neurotransmitter Studies2Not reportedNot reportedNot reportedNot reported

TC

Values in Participants · Interval/dispersion: Not reported
GroupValueSpreadLowerUpperComment
Patients With Neurotransmitter Studies0Not reportedNot reportedNot reportedNot reported

TG

Values in Participants · Interval/dispersion: Not reported
GroupValueSpreadLowerUpperComment
Patients With Neurotransmitter Studies2Not reportedNot reportedNot reportedNot reported

TT

Values in Participants · Interval/dispersion: Not reported
GroupValueSpreadLowerUpperComment
Patients With Neurotransmitter Studies13Not reportedNot reportedNot reportedNot reported
Genetic Polymorphisms for catecholamine-O-methyltransferase (COMT) rs4680

AA

Values in Participants · Interval/dispersion: Not reported
GroupValueSpreadLowerUpperComment
Patients With Neurotransmitter Studies5Not reportedNot reportedNot reportedNot reported

AG

Values in Participants · Interval/dispersion: Not reported
GroupValueSpreadLowerUpperComment
Patients With Neurotransmitter Studies7Not reportedNot reportedNot reportedNot reported

CC

Values in Participants · Interval/dispersion: Not reported
GroupValueSpreadLowerUpperComment
Patients With Neurotransmitter Studies0Not reportedNot reportedNot reportedNot reported

GG

Values in Participants · Interval/dispersion: Not reported
GroupValueSpreadLowerUpperComment
Patients With Neurotransmitter Studies5Not reportedNot reportedNot reportedNot reported

TC

Values in Participants · Interval/dispersion: Not reported
GroupValueSpreadLowerUpperComment
Patients With Neurotransmitter Studies0Not reportedNot reportedNot reportedNot reported

TG

Values in Participants · Interval/dispersion: Not reported
GroupValueSpreadLowerUpperComment
Patients With Neurotransmitter Studies0Not reportedNot reportedNot reportedNot reported

TT

Values in Participants · Interval/dispersion: Not reported
GroupValueSpreadLowerUpperComment
Patients With Neurotransmitter Studies0Not reportedNot reportedNot reportedNot reported
Genetic Polymorphisms for dopamine receptor D (DRD3) rs6280

AA

Values in Participants · Interval/dispersion: Not reported
GroupValueSpreadLowerUpperComment
Patients With Neurotransmitter Studies0Not reportedNot reportedNot reportedNot reported

AG

Values in Participants · Interval/dispersion: Not reported
GroupValueSpreadLowerUpperComment
Patients With Neurotransmitter Studies0Not reportedNot reportedNot reportedNot reported

CC

Values in Participants · Interval/dispersion: Not reported
GroupValueSpreadLowerUpperComment
Patients With Neurotransmitter Studies6Not reportedNot reportedNot reportedNot reported

GG

Values in Participants · Interval/dispersion: Not reported
GroupValueSpreadLowerUpperComment
Patients With Neurotransmitter Studies0Not reportedNot reportedNot reportedNot reported

TC

Values in Participants · Interval/dispersion: Not reported
GroupValueSpreadLowerUpperComment
Patients With Neurotransmitter Studies4Not reportedNot reportedNot reportedNot reported

TG

Values in Participants · Interval/dispersion: Not reported
GroupValueSpreadLowerUpperComment
Patients With Neurotransmitter Studies0Not reportedNot reportedNot reportedNot reported

TT

Values in Participants · Interval/dispersion: Not reported
GroupValueSpreadLowerUpperComment
Patients With Neurotransmitter Studies7Not reportedNot reportedNot reportedNot reported
Complete source fields
classes
  1. categories
    1. measurements
      1. group Id
        OG000
        value
        0
      title
      AA
    2. measurements
      1. group Id
        OG000
        value
        0
      title
      AG
    3. measurements
      1. group Id
        OG000
        value
        0
      title
      CC
    4. measurements
      1. group Id
        OG000
        value
        2
      title
      GG
    5. measurements
      1. group Id
        OG000
        value
        0
      title
      TC
    6. measurements
      1. group Id
        OG000
        value
        2
      title
      TG
    7. measurements
      1. group Id
        OG000
        value
        13
      title
      TT
    title
    Genetic Polymorphisms for monoamine oxidase A (MAOA) rs6323
  2. categories
    1. measurements
      1. group Id
        OG000
        value
        5
      title
      AA
    2. measurements
      1. group Id
        OG000
        value
        7
      title
      AG
    3. measurements
      1. group Id
        OG000
        value
        0
      title
      CC
    4. measurements
      1. group Id
        OG000
        value
        5
      title
      GG
    5. measurements
      1. group Id
        OG000
        value
        0
      title
      TC
    6. measurements
      1. group Id
        OG000
        value
        0
      title
      TG
    7. measurements
      1. group Id
        OG000
        value
        0
      title
      TT
    title
    Genetic Polymorphisms for catecholamine-O-methyltransferase (COMT) rs4680
  3. categories
    1. measurements
      1. group Id
        OG000
        value
        0
      title
      AA
    2. measurements
      1. group Id
        OG000
        value
        0
      title
      AG
    3. measurements
      1. group Id
        OG000
        value
        6
      title
      CC
    4. measurements
      1. group Id
        OG000
        value
        0
      title
      GG
    5. measurements
      1. group Id
        OG000
        value
        4
      title
      TC
    6. measurements
      1. group Id
        OG000
        value
        0
      title
      TG
    7. measurements
      1. group Id
        OG000
        value
        7
      title
      TT
    title
    Genetic Polymorphisms for dopamine receptor D (DRD3) rs6280
denoms
  1. counts
    1. group Id
      OG000
      value
      17
    units
    Participants
description
Frequencies of genetic polymorphisms were reported.
groups
  1. description
    Patients with neurotransmitter studies
    id
    OG000
    title
    Patients With Neurotransmitter Studies
param Type
COUNT_OF_PARTICIPANTS
population Description
Eligible patients who had neurotransmitter studies performed. Seventeen patients had studies performed.
reporting Status
POSTED
time Frame
At study enrollment (Day 0)
title
Pharmacogenetic Variation on Central Nervous System Transmitters
type
SECONDARY
unit Of Measure
Participants

Download exact source JSON → · Snapshot ctgov-results-191f4516d4760045304b24a0

Preserved source evidence · Not medical advice