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NCT00602667 · OUTCOME

Number of Successful Collections for Frozen and Fixed Tumor Samples

Risk-Adapted Therapy for Young Children With Embryonal Brain Tumors, Choroid Plexus Carcinoma, High Grade Glioma or Ependymoma · Source last updated 2026-05-19

Results reported by the registry submitting party. Population, time horizon, units and missing values must be read together.

Measure
COUNT_OF_PARTICIPANTS
Unit
Participants
Interval / dispersion
Not reported
Time frame
Based on samples obtained at the time of initial surgery or repeat surgery prior to treatment

What was measured

Successful collections will be defined as the number of patients who have frozen/fixed tumor samples available.

Analysis population: All eligible patients enrolled (n=290) were included in this analysis. The numbers of patients with pre-study samples were considered for these results.

Groups in this outcome

Low-Risk Group

Patients with gross total resection (GTR)/no evidence of metastatic disease (M0) medulloblastoma, nodular desmoplastic or high grade glioma histology will receive induction chemotherapy and low-risk therapy.

Intermediate-Risk Group

Patients with (M0) medulloblastoma or nodular desmoplastic histology with less than a GTR, other histologic diagnoses with no metastatic disease, will receive induction chemotherapy and intermediate-risk therapy.

High-Risk Group

Patients with central nervous system (CNS) metastatic disease will receive induction chemotherapy and high-risk therapy.

Group identifiers and denominators belong to this outcome only. They may differ in another outcome or in safety reporting.

Analysis denominator · Participants

GroupSource count
Low-Risk Group57
Intermediate-Risk Group156
High-Risk Group77

Reported measurements

Number with frozen tumor tissue
Values in Participants · Interval/dispersion: Not reported
GroupValueSpreadLowerUpperComment
Low-Risk Group27Not reportedNot reportedNot reportedNot reported
Intermediate-Risk Group73Not reportedNot reportedNot reportedNot reported
High-Risk Group32Not reportedNot reportedNot reportedNot reported
Number with fixed tumor tissue
Values in Participants · Interval/dispersion: Not reported
GroupValueSpreadLowerUpperComment
Low-Risk Group54Not reportedNot reportedNot reportedNot reported
Intermediate-Risk Group153Not reportedNot reportedNot reportedNot reported
High-Risk Group71Not reportedNot reportedNot reportedNot reported
Complete source fields
classes
  1. categories
    1. measurements
      1. group Id
        OG000
        value
        27
      2. group Id
        OG001
        value
        73
      3. group Id
        OG002
        value
        32
    title
    Number with frozen tumor tissue
  2. categories
    1. measurements
      1. group Id
        OG000
        value
        54
      2. group Id
        OG001
        value
        153
      3. group Id
        OG002
        value
        71
    title
    Number with fixed tumor tissue
denoms
  1. counts
    1. group Id
      OG000
      value
      57
    2. group Id
      OG001
      value
      156
    3. group Id
      OG002
      value
      77
    units
    Participants
description
Successful collections will be defined as the number of patients who have frozen/fixed tumor samples available.
groups
  1. description
    Patients with gross total resection (GTR)/no evidence of metastatic disease (M0) medulloblastoma, nodular desmoplastic or high grade glioma histology will receive induction chemotherapy and low-risk therapy.
    id
    OG000
    title
    Low-Risk Group
  2. description
    Patients with (M0) medulloblastoma or nodular desmoplastic histology with less than a GTR, other histologic diagnoses with no metastatic disease, will receive induction chemotherapy and intermediate-risk therapy.
    id
    OG001
    title
    Intermediate-Risk Group
  3. description
    Patients with central nervous system (CNS) metastatic disease will receive induction chemotherapy and high-risk therapy.
    id
    OG002
    title
    High-Risk Group
param Type
COUNT_OF_PARTICIPANTS
population Description
All eligible patients enrolled (n=290) were included in this analysis. The numbers of patients with pre-study samples were considered for these results.
reporting Status
POSTED
time Frame
Based on samples obtained at the time of initial surgery or repeat surgery prior to treatment
title
Number of Successful Collections for Frozen and Fixed Tumor Samples
type
SECONDARY
unit Of Measure
Participants

Download exact source JSON → · Snapshot ctgov-results-191f4516d4760045304b24a0

Preserved source evidence · Not medical advice