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NCT00602667 · OUTCOME

Numbers of Patients With Molecular Abnormalities by Tumor Type

Risk-Adapted Therapy for Young Children With Embryonal Brain Tumors, Choroid Plexus Carcinoma, High Grade Glioma or Ependymoma · Source last updated 2026-05-19

Results reported by the registry submitting party. Population, time horizon, units and missing values must be read together.

Measure: COUNT_OF_PARTICIPANTS
Unit: Participants
Interval / dispersion: Not reported
Time frame: Based on samples obtained at the time of initial surgery or repeat surgery prior to treatment

What was measured

Alterations included single nucleotide variants (SNPs), amplifications, deletions, translocations, indels, and germline alterations. Cytogenetic information shows gains and losses as specified in the table of measured values.

Analysis population: Eligible patients with molecularly confirmed medulloblastoma (n=76) were included in these analyses. Not all patients had data available for each gene.

Groups in this outcome

Low-risk SHH Patients

Sonic hedgehog (SHH) medulloblastoma subgroup patients in the low-risk group

Intermediate-risk SHH Patients

Sonic hedgehog (SHH) medulloblastoma subgroup patients in the intermediate-risk group

High-risk SHH Patients

Sonic hedgehog (SHH) medulloblastoma subgroup patients in the high-risk group

Low-risk Group 3 Patients

Group 3 (G3) medulloblastoma subgroup patients in the low-risk group

Intermediate-risk Group 3 Patients

Group 3 medulloblastoma subgroup patients in the intermediate-risk group

High-risk Group 3 Patients

Group 3 medulloblastoma subgroup patients in the high-risk group

Low-risk Group 4 Patients

Group 4 (G4) medulloblastoma subgroup patients in the low-risk group

Intermediate-risk Group 4 Patients

Group 4 (G4) medulloblastoma subgroup patients in the intermediate-risk group

High-risk Group 4 Patients

Group 4 medulloblastoma subgroup patients in the high-risk group

Group identifiers and denominators belong to this outcome only. They may differ in another outcome or in safety reporting.

Analysis denominator · Participants

Group	Source count
Low-risk SHH Patients	23
Intermediate-risk SHH Patients	8
High-risk SHH Patients	11
Low-risk Group 3 Patients	0
Intermediate-risk Group 3 Patients	13
High-risk Group 3 Patients	11
Low-risk Group 4 Patients	0
Intermediate-risk Group 4 Patients	8
High-risk Group 4 Patients	2

Reported measurements

PTCH1 alteration

Analysis denominator · Participants

Group	Source count
Low-risk SHH Patients	23
Intermediate-risk SHH Patients	8
High-risk SHH Patients	11
Low-risk Group 3 Patients	0
Intermediate-risk Group 3 Patients	12
High-risk Group 3 Patients	11
Low-risk Group 4 Patients	0
Intermediate-risk Group 4 Patients	8
High-risk Group 4 Patients	2

Values in Participants · Interval/dispersion: Not reported
Group	Value	Spread	Lower	Upper	Comment
Low-risk SHH Patients	7	Not reported	Not reported	Not reported	Not reported
Intermediate-risk SHH Patients	4	Not reported	Not reported	Not reported	Not reported
High-risk SHH Patients	3	Not reported	Not reported	Not reported	Not reported
Intermediate-risk Group 3 Patients	0	Not reported	Not reported	Not reported	Not reported
High-risk Group 3 Patients	0	Not reported	Not reported	Not reported	Not reported
Intermediate-risk Group 4 Patients	0	Not reported	Not reported	Not reported	Not reported
High-risk Group 4 Patients	0	Not reported	Not reported	Not reported	Not reported

SUFU alteration

Analysis denominator · Participants

Group	Source count
Low-risk SHH Patients	23
Intermediate-risk SHH Patients	8
High-risk SHH Patients	11
Low-risk Group 3 Patients	0
Intermediate-risk Group 3 Patients	12
High-risk Group 3 Patients	11
Low-risk Group 4 Patients	0
Intermediate-risk Group 4 Patients	8
High-risk Group 4 Patients	2

Values in Participants · Interval/dispersion: Not reported
Group	Value	Spread	Lower	Upper	Comment
Low-risk SHH Patients	6	Not reported	Not reported	Not reported	Not reported
Intermediate-risk SHH Patients	1	Not reported	Not reported	Not reported	Not reported
High-risk SHH Patients	1	Not reported	Not reported	Not reported	Not reported
Intermediate-risk Group 3 Patients	0	Not reported	Not reported	Not reported	Not reported
High-risk Group 3 Patients	0	Not reported	Not reported	Not reported	Not reported
Intermediate-risk Group 4 Patients	0	Not reported	Not reported	Not reported	Not reported
High-risk Group 4 Patients	0	Not reported	Not reported	Not reported	Not reported

KMT2D alteration

Analysis denominator · Participants

Group	Source count
Low-risk SHH Patients	22
Intermediate-risk SHH Patients	6
High-risk SHH Patients	10
Low-risk Group 3 Patients	0
Intermediate-risk Group 3 Patients	9
High-risk Group 3 Patients	6
Low-risk Group 4 Patients	0
Intermediate-risk Group 4 Patients	5
High-risk Group 4 Patients	2

Values in Participants · Interval/dispersion: Not reported
Group	Value	Spread	Lower	Upper	Comment
Low-risk SHH Patients	5	Not reported	Not reported	Not reported	Not reported
Intermediate-risk SHH Patients	1	Not reported	Not reported	Not reported	Not reported
High-risk SHH Patients	3	Not reported	Not reported	Not reported	Not reported
Intermediate-risk Group 3 Patients	0	Not reported	Not reported	Not reported	Not reported
High-risk Group 3 Patients	0	Not reported	Not reported	Not reported	Not reported
Intermediate-risk Group 4 Patients	0	Not reported	Not reported	Not reported	Not reported
High-risk Group 4 Patients	0	Not reported	Not reported	Not reported	Not reported

SMO alteration

Analysis denominator · Participants

Group	Source count
Low-risk SHH Patients	22
Intermediate-risk SHH Patients	6
High-risk SHH Patients	10
Low-risk Group 3 Patients	0
Intermediate-risk Group 3 Patients	9
High-risk Group 3 Patients	6
Low-risk Group 4 Patients	0
Intermediate-risk Group 4 Patients	5
High-risk Group 4 Patients	1

Values in Participants · Interval/dispersion: Not reported
Group	Value	Spread	Lower	Upper	Comment
Low-risk SHH Patients	2	Not reported	Not reported	Not reported	Not reported
Intermediate-risk SHH Patients	0	Not reported	Not reported	Not reported	Not reported
High-risk SHH Patients	1	Not reported	Not reported	Not reported	Not reported
Intermediate-risk Group 3 Patients	0	Not reported	Not reported	Not reported	Not reported
High-risk Group 3 Patients	0	Not reported	Not reported	Not reported	Not reported
Intermediate-risk Group 4 Patients	0	Not reported	Not reported	Not reported	Not reported
High-risk Group 4 Patients	0	Not reported	Not reported	Not reported	Not reported

BCOR alteration

Analysis denominator · Participants

Group	Source count
Low-risk SHH Patients	22
Intermediate-risk SHH Patients	6
High-risk SHH Patients	10
Low-risk Group 3 Patients	0
Intermediate-risk Group 3 Patients	9
High-risk Group 3 Patients	6
Low-risk Group 4 Patients	0
Intermediate-risk Group 4 Patients	5
High-risk Group 4 Patients	1

Values in Participants · Interval/dispersion: Not reported
Group	Value	Spread	Lower	Upper	Comment
Low-risk SHH Patients	1	Not reported	Not reported	Not reported	Not reported
Intermediate-risk SHH Patients	0	Not reported	Not reported	Not reported	Not reported
High-risk SHH Patients	0	Not reported	Not reported	Not reported	Not reported
Intermediate-risk Group 3 Patients	0	Not reported	Not reported	Not reported	Not reported
High-risk Group 3 Patients	0	Not reported	Not reported	Not reported	Not reported
Intermediate-risk Group 4 Patients	0	Not reported	Not reported	Not reported	Not reported
High-risk Group 4 Patients	0	Not reported	Not reported	Not reported	Not reported

PTEN alteration

Analysis denominator · Participants

Group	Source count
Low-risk SHH Patients	23
Intermediate-risk SHH Patients	8
High-risk SHH Patients	11
Low-risk Group 3 Patients	0
Intermediate-risk Group 3 Patients	12
High-risk Group 3 Patients	11
Low-risk Group 4 Patients	0
Intermediate-risk Group 4 Patients	8
High-risk Group 4 Patients	2

Values in Participants · Interval/dispersion: Not reported
Group	Value	Spread	Lower	Upper	Comment
Low-risk SHH Patients	1	Not reported	Not reported	Not reported	Not reported
Intermediate-risk SHH Patients	0	Not reported	Not reported	Not reported	Not reported
High-risk SHH Patients	0	Not reported	Not reported	Not reported	Not reported
Intermediate-risk Group 3 Patients	0	Not reported	Not reported	Not reported	Not reported
High-risk Group 3 Patients	0	Not reported	Not reported	Not reported	Not reported
Intermediate-risk Group 4 Patients	0	Not reported	Not reported	Not reported	Not reported
High-risk Group 4 Patients	0	Not reported	Not reported	Not reported	Not reported

BRCA2 alteration

Analysis denominator · Participants

Group	Source count
Low-risk SHH Patients	22
Intermediate-risk SHH Patients	6
High-risk SHH Patients	10
Low-risk Group 3 Patients	0
Intermediate-risk Group 3 Patients	9
High-risk Group 3 Patients	6
Low-risk Group 4 Patients	0
Intermediate-risk Group 4 Patients	5
High-risk Group 4 Patients	1

Values in Participants · Interval/dispersion: Not reported
Group	Value	Spread	Lower	Upper	Comment
Low-risk SHH Patients	0	Not reported	Not reported	Not reported	Not reported
Intermediate-risk SHH Patients	0	Not reported	Not reported	Not reported	Not reported
High-risk SHH Patients	0	Not reported	Not reported	Not reported	Not reported
Intermediate-risk Group 3 Patients	0	Not reported	Not reported	Not reported	Not reported
High-risk Group 3 Patients	0	Not reported	Not reported	Not reported	Not reported
Intermediate-risk Group 4 Patients	0	Not reported	Not reported	Not reported	Not reported
High-risk Group 4 Patients	0	Not reported	Not reported	Not reported	Not reported

GLI2 alteration

Analysis denominator · Participants

Group	Source count
Low-risk SHH Patients	23
Intermediate-risk SHH Patients	8
High-risk SHH Patients	11
Low-risk Group 3 Patients	0
Intermediate-risk Group 3 Patients	11
High-risk Group 3 Patients	11
Low-risk Group 4 Patients	0
Intermediate-risk Group 4 Patients	7
High-risk Group 4 Patients	1

Values in Participants · Interval/dispersion: Not reported
Group	Value	Spread	Lower	Upper	Comment
Low-risk SHH Patients	0	Not reported	Not reported	Not reported	Not reported
Intermediate-risk SHH Patients	0	Not reported	Not reported	Not reported	Not reported
High-risk SHH Patients	0	Not reported	Not reported	Not reported	Not reported
Intermediate-risk Group 3 Patients	0	Not reported	Not reported	Not reported	Not reported
High-risk Group 3 Patients	0	Not reported	Not reported	Not reported	Not reported
Intermediate-risk Group 4 Patients	0	Not reported	Not reported	Not reported	Not reported
High-risk Group 4 Patients	0	Not reported	Not reported	Not reported	Not reported

SMARCA4 alteration

Analysis denominator · Participants

Group	Source count
Low-risk SHH Patients	22
Intermediate-risk SHH Patients	6
High-risk SHH Patients	10
Low-risk Group 3 Patients	0
Intermediate-risk Group 3 Patients	9
High-risk Group 3 Patients	6
Low-risk Group 4 Patients	0
Intermediate-risk Group 4 Patients	5
High-risk Group 4 Patients	1

Values in Participants · Interval/dispersion: Not reported
Group	Value	Spread	Lower	Upper	Comment
Low-risk SHH Patients	2	Not reported	Not reported	Not reported	Not reported
Intermediate-risk SHH Patients	0	Not reported	Not reported	Not reported	Not reported
High-risk SHH Patients	0	Not reported	Not reported	Not reported	Not reported
Intermediate-risk Group 3 Patients	1	Not reported	Not reported	Not reported	Not reported
High-risk Group 3 Patients	0	Not reported	Not reported	Not reported	Not reported
Intermediate-risk Group 4 Patients	0	Not reported	Not reported	Not reported	Not reported
High-risk Group 4 Patients	0	Not reported	Not reported	Not reported	Not reported

TP53 alteration

Analysis denominator · Participants

Group	Source count
Low-risk SHH Patients	23
Intermediate-risk SHH Patients	8
High-risk SHH Patients	11
Low-risk Group 3 Patients	0
Intermediate-risk Group 3 Patients	12
High-risk Group 3 Patients	11
Low-risk Group 4 Patients	0
Intermediate-risk Group 4 Patients	8
High-risk Group 4 Patients	2

Values in Participants · Interval/dispersion: Not reported
Group	Value	Spread	Lower	Upper	Comment
Low-risk SHH Patients	0	Not reported	Not reported	Not reported	Not reported
Intermediate-risk SHH Patients	0	Not reported	Not reported	Not reported	Not reported
High-risk SHH Patients	0	Not reported	Not reported	Not reported	Not reported
Intermediate-risk Group 3 Patients	0	Not reported	Not reported	Not reported	Not reported
High-risk Group 3 Patients	0	Not reported	Not reported	Not reported	Not reported
Intermediate-risk Group 4 Patients	0	Not reported	Not reported	Not reported	Not reported
High-risk Group 4 Patients	0	Not reported	Not reported	Not reported	Not reported

MYCN amplification

Analysis denominator · Participants

Group	Source count
Low-risk SHH Patients	23
Intermediate-risk SHH Patients	8
High-risk SHH Patients	11
Low-risk Group 3 Patients	0
Intermediate-risk Group 3 Patients	12
High-risk Group 3 Patients	11
Low-risk Group 4 Patients	0
Intermediate-risk Group 4 Patients	8
High-risk Group 4 Patients	2

Values in Participants · Interval/dispersion: Not reported
Group	Value	Spread	Lower	Upper	Comment
Low-risk SHH Patients	0	Not reported	Not reported	Not reported	Not reported
Intermediate-risk SHH Patients	1	Not reported	Not reported	Not reported	Not reported
High-risk SHH Patients	0	Not reported	Not reported	Not reported	Not reported
Intermediate-risk Group 3 Patients	0	Not reported	Not reported	Not reported	Not reported
High-risk Group 3 Patients	1	Not reported	Not reported	Not reported	Not reported
Intermediate-risk Group 4 Patients	0	Not reported	Not reported	Not reported	Not reported
High-risk Group 4 Patients	0	Not reported	Not reported	Not reported	Not reported

chr2p gain/amplification

Analysis denominator · Participants

Group	Source count
Low-risk SHH Patients	23
Intermediate-risk SHH Patients	8
High-risk SHH Patients	11
Low-risk Group 3 Patients	0
Intermediate-risk Group 3 Patients	11
High-risk Group 3 Patients	11
Low-risk Group 4 Patients	0
Intermediate-risk Group 4 Patients	7
High-risk Group 4 Patients	1

Values in Participants · Interval/dispersion: Not reported
Group	Value	Spread	Lower	Upper	Comment
Low-risk SHH Patients	5	Not reported	Not reported	Not reported	Not reported
Intermediate-risk SHH Patients	0	Not reported	Not reported	Not reported	Not reported
High-risk SHH Patients	4	Not reported	Not reported	Not reported	Not reported
Intermediate-risk Group 3 Patients	0	Not reported	Not reported	Not reported	Not reported
High-risk Group 3 Patients	1	Not reported	Not reported	Not reported	Not reported
Intermediate-risk Group 4 Patients	0	Not reported	Not reported	Not reported	Not reported
High-risk Group 4 Patients	0	Not reported	Not reported	Not reported	Not reported

chr2p loss/deletion

Analysis denominator · Participants

Group	Source count
Low-risk SHH Patients	23
Intermediate-risk SHH Patients	8
High-risk SHH Patients	11
Low-risk Group 3 Patients	0
Intermediate-risk Group 3 Patients	11
High-risk Group 3 Patients	11
Low-risk Group 4 Patients	0
Intermediate-risk Group 4 Patients	7
High-risk Group 4 Patients	1

Values in Participants · Interval/dispersion: Not reported
Group	Value	Spread	Lower	Upper	Comment
Low-risk SHH Patients	0	Not reported	Not reported	Not reported	Not reported
Intermediate-risk SHH Patients	0	Not reported	Not reported	Not reported	Not reported
High-risk SHH Patients	0	Not reported	Not reported	Not reported	Not reported
Intermediate-risk Group 3 Patients	1	Not reported	Not reported	Not reported	Not reported
High-risk Group 3 Patients	0	Not reported	Not reported	Not reported	Not reported
Intermediate-risk Group 4 Patients	1	Not reported	Not reported	Not reported	Not reported
High-risk Group 4 Patients	0	Not reported	Not reported	Not reported	Not reported

chr2q gain/amplification

Analysis denominator · Participants

Group	Source count
Low-risk SHH Patients	23
Intermediate-risk SHH Patients	8
High-risk SHH Patients	11
Low-risk Group 3 Patients	0
Intermediate-risk Group 3 Patients	11
High-risk Group 3 Patients	11
Low-risk Group 4 Patients	0
Intermediate-risk Group 4 Patients	7
High-risk Group 4 Patients	1

Values in Participants · Interval/dispersion: Not reported
Group	Value	Spread	Lower	Upper	Comment
Low-risk SHH Patients	5	Not reported	Not reported	Not reported	Not reported
Intermediate-risk SHH Patients	0	Not reported	Not reported	Not reported	Not reported
High-risk SHH Patients	4	Not reported	Not reported	Not reported	Not reported
Intermediate-risk Group 3 Patients	0	Not reported	Not reported	Not reported	Not reported
High-risk Group 3 Patients	1	Not reported	Not reported	Not reported	Not reported
Intermediate-risk Group 4 Patients	0	Not reported	Not reported	Not reported	Not reported
High-risk Group 4 Patients	0	Not reported	Not reported	Not reported	Not reported

chr2q loss/deletion

Analysis denominator · Participants

Group	Source count
Low-risk SHH Patients	23
Intermediate-risk SHH Patients	8
High-risk SHH Patients	11
Low-risk Group 3 Patients	0
Intermediate-risk Group 3 Patients	11
High-risk Group 3 Patients	11
Low-risk Group 4 Patients	0
Intermediate-risk Group 4 Patients	7
High-risk Group 4 Patients	1

Values in Participants · Interval/dispersion: Not reported
Group	Value	Spread	Lower	Upper	Comment
Low-risk SHH Patients	0	Not reported	Not reported	Not reported	Not reported
Intermediate-risk SHH Patients	0	Not reported	Not reported	Not reported	Not reported
High-risk SHH Patients	0	Not reported	Not reported	Not reported	Not reported
Intermediate-risk Group 3 Patients	1	Not reported	Not reported	Not reported	Not reported
High-risk Group 3 Patients	0	Not reported	Not reported	Not reported	Not reported
Intermediate-risk Group 4 Patients	1	Not reported	Not reported	Not reported	Not reported
High-risk Group 4 Patients	0	Not reported	Not reported	Not reported	Not reported

chr6p gain/amplification

Analysis denominator · Participants

Group	Source count
Low-risk SHH Patients	23
Intermediate-risk SHH Patients	8
High-risk SHH Patients	11
Low-risk Group 3 Patients	0
Intermediate-risk Group 3 Patients	11
High-risk Group 3 Patients	11
Low-risk Group 4 Patients	0
Intermediate-risk Group 4 Patients	7
High-risk Group 4 Patients	1

Values in Participants · Interval/dispersion: Not reported
Group	Value	Spread	Lower	Upper	Comment
Low-risk SHH Patients	1	Not reported	Not reported	Not reported	Not reported
Intermediate-risk SHH Patients	0	Not reported	Not reported	Not reported	Not reported
High-risk SHH Patients	0	Not reported	Not reported	Not reported	Not reported
Intermediate-risk Group 3 Patients	2	Not reported	Not reported	Not reported	Not reported
High-risk Group 3 Patients	3	Not reported	Not reported	Not reported	Not reported
Intermediate-risk Group 4 Patients	1	Not reported	Not reported	Not reported	Not reported
High-risk Group 4 Patients	0	Not reported	Not reported	Not reported	Not reported

chr6p loss/deletion

Analysis denominator · Participants

Group	Source count
Low-risk SHH Patients	23
Intermediate-risk SHH Patients	8
High-risk SHH Patients	11
Low-risk Group 3 Patients	0
Intermediate-risk Group 3 Patients	11
High-risk Group 3 Patients	11
Low-risk Group 4 Patients	0
Intermediate-risk Group 4 Patients	7
High-risk Group 4 Patients	1

Values in Participants · Interval/dispersion: Not reported
Group	Value	Spread	Lower	Upper	Comment
Low-risk SHH Patients	0	Not reported	Not reported	Not reported	Not reported
Intermediate-risk SHH Patients	0	Not reported	Not reported	Not reported	Not reported
High-risk SHH Patients	0	Not reported	Not reported	Not reported	Not reported
Intermediate-risk Group 3 Patients	0	Not reported	Not reported	Not reported	Not reported
High-risk Group 3 Patients	2	Not reported	Not reported	Not reported	Not reported
Intermediate-risk Group 4 Patients	0	Not reported	Not reported	Not reported	Not reported
High-risk Group 4 Patients	0	Not reported	Not reported	Not reported	Not reported

chr6q gain/amplification

Analysis denominator · Participants

Group	Source count
Low-risk SHH Patients	23
Intermediate-risk SHH Patients	8
High-risk SHH Patients	11
Low-risk Group 3 Patients	0
Intermediate-risk Group 3 Patients	11
High-risk Group 3 Patients	11
Low-risk Group 4 Patients	0
Intermediate-risk Group 4 Patients	7
High-risk Group 4 Patients	1

Values in Participants · Interval/dispersion: Not reported
Group	Value	Spread	Lower	Upper	Comment
Low-risk SHH Patients	1	Not reported	Not reported	Not reported	Not reported
Intermediate-risk SHH Patients	0	Not reported	Not reported	Not reported	Not reported
High-risk SHH Patients	0	Not reported	Not reported	Not reported	Not reported
Intermediate-risk Group 3 Patients	2	Not reported	Not reported	Not reported	Not reported
High-risk Group 3 Patients	3	Not reported	Not reported	Not reported	Not reported
Intermediate-risk Group 4 Patients	1	Not reported	Not reported	Not reported	Not reported
High-risk Group 4 Patients	0	Not reported	Not reported	Not reported	Not reported

chr6q loss/deletion

Analysis denominator · Participants

Group	Source count
Low-risk SHH Patients	23
Intermediate-risk SHH Patients	8
High-risk SHH Patients	11
Low-risk Group 3 Patients	0
Intermediate-risk Group 3 Patients	11
High-risk Group 3 Patients	11
Low-risk Group 4 Patients	0
Intermediate-risk Group 4 Patients	7
High-risk Group 4 Patients	1

Values in Participants · Interval/dispersion: Not reported
Group	Value	Spread	Lower	Upper	Comment
Low-risk SHH Patients	0	Not reported	Not reported	Not reported	Not reported
Intermediate-risk SHH Patients	0	Not reported	Not reported	Not reported	Not reported
High-risk SHH Patients	0	Not reported	Not reported	Not reported	Not reported
Intermediate-risk Group 3 Patients	0	Not reported	Not reported	Not reported	Not reported
High-risk Group 3 Patients	2	Not reported	Not reported	Not reported	Not reported
Intermediate-risk Group 4 Patients	0	Not reported	Not reported	Not reported	Not reported
High-risk Group 4 Patients	0	Not reported	Not reported	Not reported	Not reported

chr8p gain/amplification

Analysis denominator · Participants

Group	Source count
Low-risk SHH Patients	23
Intermediate-risk SHH Patients	8
High-risk SHH Patients	11
Low-risk Group 3 Patients	0
Intermediate-risk Group 3 Patients	11
High-risk Group 3 Patients	11
Low-risk Group 4 Patients	0
Intermediate-risk Group 4 Patients	7
High-risk Group 4 Patients	1

Values in Participants · Interval/dispersion: Not reported
Group	Value	Spread	Lower	Upper	Comment
Low-risk SHH Patients	1	Not reported	Not reported	Not reported	Not reported
Intermediate-risk SHH Patients	0	Not reported	Not reported	Not reported	Not reported
High-risk SHH Patients	0	Not reported	Not reported	Not reported	Not reported
Intermediate-risk Group 3 Patients	1	Not reported	Not reported	Not reported	Not reported
High-risk Group 3 Patients	0	Not reported	Not reported	Not reported	Not reported
Intermediate-risk Group 4 Patients	0	Not reported	Not reported	Not reported	Not reported
High-risk Group 4 Patients	0	Not reported	Not reported	Not reported	Not reported

chr8p loss/deletion

Analysis denominator · Participants

Group	Source count
Low-risk SHH Patients	23
Intermediate-risk SHH Patients	8
High-risk SHH Patients	11
Low-risk Group 3 Patients	0
Intermediate-risk Group 3 Patients	11
High-risk Group 3 Patients	11
Low-risk Group 4 Patients	0
Intermediate-risk Group 4 Patients	7
High-risk Group 4 Patients	1

Values in Participants · Interval/dispersion: Not reported
Group	Value	Spread	Lower	Upper	Comment
Low-risk SHH Patients	0	Not reported	Not reported	Not reported	Not reported
Intermediate-risk SHH Patients	0	Not reported	Not reported	Not reported	Not reported
High-risk SHH Patients	0	Not reported	Not reported	Not reported	Not reported
Intermediate-risk Group 3 Patients	2	Not reported	Not reported	Not reported	Not reported
High-risk Group 3 Patients	7	Not reported	Not reported	Not reported	Not reported
Intermediate-risk Group 4 Patients	4	Not reported	Not reported	Not reported	Not reported
High-risk Group 4 Patients	1	Not reported	Not reported	Not reported	Not reported

chr8q gain/amplification

Analysis denominator · Participants

Group	Source count
Low-risk SHH Patients	23
Intermediate-risk SHH Patients	8
High-risk SHH Patients	11
Low-risk Group 3 Patients	0
Intermediate-risk Group 3 Patients	11
High-risk Group 3 Patients	11
Low-risk Group 4 Patients	0
Intermediate-risk Group 4 Patients	7
High-risk Group 4 Patients	1

Values in Participants · Interval/dispersion: Not reported
Group	Value	Spread	Lower	Upper	Comment
Low-risk SHH Patients	1	Not reported	Not reported	Not reported	Not reported
Intermediate-risk SHH Patients	0	Not reported	Not reported	Not reported	Not reported
High-risk SHH Patients	0	Not reported	Not reported	Not reported	Not reported
Intermediate-risk Group 3 Patients	2	Not reported	Not reported	Not reported	Not reported
High-risk Group 3 Patients	0	Not reported	Not reported	Not reported	Not reported
Intermediate-risk Group 4 Patients	0	Not reported	Not reported	Not reported	Not reported
High-risk Group 4 Patients	0	Not reported	Not reported	Not reported	Not reported

chr8q loss/deletion

Analysis denominator · Participants

Group	Source count
Low-risk SHH Patients	23
Intermediate-risk SHH Patients	8
High-risk SHH Patients	11
Low-risk Group 3 Patients	0
Intermediate-risk Group 3 Patients	11
High-risk Group 3 Patients	11
Low-risk Group 4 Patients	0
Intermediate-risk Group 4 Patients	7
High-risk Group 4 Patients	1

Values in Participants · Interval/dispersion: Not reported
Group	Value	Spread	Lower	Upper	Comment
Low-risk SHH Patients	0	Not reported	Not reported	Not reported	Not reported
Intermediate-risk SHH Patients	0	Not reported	Not reported	Not reported	Not reported
High-risk SHH Patients	0	Not reported	Not reported	Not reported	Not reported
Intermediate-risk Group 3 Patients	1	Not reported	Not reported	Not reported	Not reported
High-risk Group 3 Patients	6	Not reported	Not reported	Not reported	Not reported
Intermediate-risk Group 4 Patients	4	Not reported	Not reported	Not reported	Not reported
High-risk Group 4 Patients	1	Not reported	Not reported	Not reported	Not reported

chr9p gain/amplification

Analysis denominator · Participants

Group	Source count
Low-risk SHH Patients	23
Intermediate-risk SHH Patients	8
High-risk SHH Patients	11
Low-risk Group 3 Patients	0
Intermediate-risk Group 3 Patients	11
High-risk Group 3 Patients	11
Low-risk Group 4 Patients	0
Intermediate-risk Group 4 Patients	7
High-risk Group 4 Patients	1

Values in Participants · Interval/dispersion: Not reported
Group	Value	Spread	Lower	Upper	Comment
Low-risk SHH Patients	4	Not reported	Not reported	Not reported	Not reported
Intermediate-risk SHH Patients	4	Not reported	Not reported	Not reported	Not reported
High-risk SHH Patients	3	Not reported	Not reported	Not reported	Not reported
Intermediate-risk Group 3 Patients	1	Not reported	Not reported	Not reported	Not reported
High-risk Group 3 Patients	0	Not reported	Not reported	Not reported	Not reported
Intermediate-risk Group 4 Patients	1	Not reported	Not reported	Not reported	Not reported
High-risk Group 4 Patients	0	Not reported	Not reported	Not reported	Not reported

chr9p loss/deletion

Analysis denominator · Participants

Group	Source count
Low-risk SHH Patients	23
Intermediate-risk SHH Patients	8
High-risk SHH Patients	11
Low-risk Group 3 Patients	0
Intermediate-risk Group 3 Patients	11
High-risk Group 3 Patients	11
Low-risk Group 4 Patients	0
Intermediate-risk Group 4 Patients	7
High-risk Group 4 Patients	1

Values in Participants · Interval/dispersion: Not reported
Group	Value	Spread	Lower	Upper	Comment
Low-risk SHH Patients	4	Not reported	Not reported	Not reported	Not reported
Intermediate-risk SHH Patients	0	Not reported	Not reported	Not reported	Not reported
High-risk SHH Patients	0	Not reported	Not reported	Not reported	Not reported
Intermediate-risk Group 3 Patients	0	Not reported	Not reported	Not reported	Not reported
High-risk Group 3 Patients	3	Not reported	Not reported	Not reported	Not reported
Intermediate-risk Group 4 Patients	0	Not reported	Not reported	Not reported	Not reported
High-risk Group 4 Patients	0	Not reported	Not reported	Not reported	Not reported

chr9q gain/amplification

Analysis denominator · Participants

Group	Source count
Low-risk SHH Patients	23
Intermediate-risk SHH Patients	8
High-risk SHH Patients	11
Low-risk Group 3 Patients	0
Intermediate-risk Group 3 Patients	11
High-risk Group 3 Patients	11
Low-risk Group 4 Patients	0
Intermediate-risk Group 4 Patients	7
High-risk Group 4 Patients	1

Values in Participants · Interval/dispersion: Not reported
Group	Value	Spread	Lower	Upper	Comment
Low-risk SHH Patients	2	Not reported	Not reported	Not reported	Not reported
Intermediate-risk SHH Patients	0	Not reported	Not reported	Not reported	Not reported
High-risk SHH Patients	1	Not reported	Not reported	Not reported	Not reported
Intermediate-risk Group 3 Patients	0	Not reported	Not reported	Not reported	Not reported
High-risk Group 3 Patients	0	Not reported	Not reported	Not reported	Not reported
Intermediate-risk Group 4 Patients	1	Not reported	Not reported	Not reported	Not reported
High-risk Group 4 Patients	0	Not reported	Not reported	Not reported	Not reported

chr9q loss/deletion

Analysis denominator · Participants

Group	Source count
Low-risk SHH Patients	23
Intermediate-risk SHH Patients	8
High-risk SHH Patients	11
Low-risk Group 3 Patients	0
Intermediate-risk Group 3 Patients	11
High-risk Group 3 Patients	11
Low-risk Group 4 Patients	0
Intermediate-risk Group 4 Patients	7
High-risk Group 4 Patients	1

Values in Participants · Interval/dispersion: Not reported
Group	Value	Spread	Lower	Upper	Comment
Low-risk SHH Patients	6	Not reported	Not reported	Not reported	Not reported
Intermediate-risk SHH Patients	5	Not reported	Not reported	Not reported	Not reported
High-risk SHH Patients	2	Not reported	Not reported	Not reported	Not reported
Intermediate-risk Group 3 Patients	0	Not reported	Not reported	Not reported	Not reported
High-risk Group 3 Patients	3	Not reported	Not reported	Not reported	Not reported
Intermediate-risk Group 4 Patients	0	Not reported	Not reported	Not reported	Not reported
High-risk Group 4 Patients	0	Not reported	Not reported	Not reported	Not reported

chr10p gain/amplification

Analysis denominator · Participants

Group	Source count
Low-risk SHH Patients	23
Intermediate-risk SHH Patients	8
High-risk SHH Patients	11
Low-risk Group 3 Patients	0
Intermediate-risk Group 3 Patients	11
High-risk Group 3 Patients	11
Low-risk Group 4 Patients	0
Intermediate-risk Group 4 Patients	7
High-risk Group 4 Patients	1

Values in Participants · Interval/dispersion: Not reported
Group	Value	Spread	Lower	Upper	Comment
Low-risk SHH Patients	0	Not reported	Not reported	Not reported	Not reported
Intermediate-risk SHH Patients	0	Not reported	Not reported	Not reported	Not reported
High-risk SHH Patients	0	Not reported	Not reported	Not reported	Not reported
Intermediate-risk Group 3 Patients	0	Not reported	Not reported	Not reported	Not reported
High-risk Group 3 Patients	0	Not reported	Not reported	Not reported	Not reported
Intermediate-risk Group 4 Patients	0	Not reported	Not reported	Not reported	Not reported
High-risk Group 4 Patients	0	Not reported	Not reported	Not reported	Not reported

chr10p loss/deletion

Analysis denominator · Participants

Group	Source count
Low-risk SHH Patients	23
Intermediate-risk SHH Patients	8
High-risk SHH Patients	11
Low-risk Group 3 Patients	0
Intermediate-risk Group 3 Patients	11
High-risk Group 3 Patients	11
Low-risk Group 4 Patients	0
Intermediate-risk Group 4 Patients	7
High-risk Group 4 Patients	1

Values in Participants · Interval/dispersion: Not reported
Group	Value	Spread	Lower	Upper	Comment
Low-risk SHH Patients	0	Not reported	Not reported	Not reported	Not reported
Intermediate-risk SHH Patients	0	Not reported	Not reported	Not reported	Not reported
High-risk SHH Patients	0	Not reported	Not reported	Not reported	Not reported
Intermediate-risk Group 3 Patients	5	Not reported	Not reported	Not reported	Not reported
High-risk Group 3 Patients	7	Not reported	Not reported	Not reported	Not reported
Intermediate-risk Group 4 Patients	0	Not reported	Not reported	Not reported	Not reported
High-risk Group 4 Patients	0	Not reported	Not reported	Not reported	Not reported

chr10q gain/amplification

Analysis denominator · Participants

Group	Source count
Low-risk SHH Patients	23
Intermediate-risk SHH Patients	8
High-risk SHH Patients	11
Low-risk Group 3 Patients	0
Intermediate-risk Group 3 Patients	11
High-risk Group 3 Patients	11
Low-risk Group 4 Patients	0
Intermediate-risk Group 4 Patients	7
High-risk Group 4 Patients	1

Values in Participants · Interval/dispersion: Not reported
Group	Value	Spread	Lower	Upper	Comment
Low-risk SHH Patients	0	Not reported	Not reported	Not reported	Not reported
Intermediate-risk SHH Patients	0	Not reported	Not reported	Not reported	Not reported
High-risk SHH Patients	0	Not reported	Not reported	Not reported	Not reported
Intermediate-risk Group 3 Patients	0	Not reported	Not reported	Not reported	Not reported
High-risk Group 3 Patients	0	Not reported	Not reported	Not reported	Not reported
Intermediate-risk Group 4 Patients	0	Not reported	Not reported	Not reported	Not reported
High-risk Group 4 Patients	0	Not reported	Not reported	Not reported	Not reported

chr10q loss/deletion

Analysis denominator · Participants

Group	Source count
Low-risk SHH Patients	23
Intermediate-risk SHH Patients	8
High-risk SHH Patients	11
Low-risk Group 3 Patients	0
Intermediate-risk Group 3 Patients	11
High-risk Group 3 Patients	11
Low-risk Group 4 Patients	0
Intermediate-risk Group 4 Patients	7
High-risk Group 4 Patients	1

Values in Participants · Interval/dispersion: Not reported
Group	Value	Spread	Lower	Upper	Comment
Low-risk SHH Patients	3	Not reported	Not reported	Not reported	Not reported
Intermediate-risk SHH Patients	2	Not reported	Not reported	Not reported	Not reported
High-risk SHH Patients	1	Not reported	Not reported	Not reported	Not reported
Intermediate-risk Group 3 Patients	5	Not reported	Not reported	Not reported	Not reported
High-risk Group 3 Patients	8	Not reported	Not reported	Not reported	Not reported
Intermediate-risk Group 4 Patients	0	Not reported	Not reported	Not reported	Not reported
High-risk Group 4 Patients	0	Not reported	Not reported	Not reported	Not reported

chr20p gain/amplification

Analysis denominator · Participants

Group	Source count
Low-risk SHH Patients	23
Intermediate-risk SHH Patients	8
High-risk SHH Patients	11
Low-risk Group 3 Patients	0
Intermediate-risk Group 3 Patients	11
High-risk Group 3 Patients	11
Low-risk Group 4 Patients	0
Intermediate-risk Group 4 Patients	7
High-risk Group 4 Patients	1

Values in Participants · Interval/dispersion: Not reported
Group	Value	Spread	Lower	Upper	Comment
Low-risk SHH Patients	0	Not reported	Not reported	Not reported	Not reported
Intermediate-risk SHH Patients	0	Not reported	Not reported	Not reported	Not reported
High-risk SHH Patients	0	Not reported	Not reported	Not reported	Not reported
Intermediate-risk Group 3 Patients	0	Not reported	Not reported	Not reported	Not reported
High-risk Group 3 Patients	0	Not reported	Not reported	Not reported	Not reported
Intermediate-risk Group 4 Patients	0	Not reported	Not reported	Not reported	Not reported
High-risk Group 4 Patients	0	Not reported	Not reported	Not reported	Not reported

chr20p loss/deletion

Analysis denominator · Participants

Group	Source count
Low-risk SHH Patients	23
Intermediate-risk SHH Patients	8
High-risk SHH Patients	11
Low-risk Group 3 Patients	0
Intermediate-risk Group 3 Patients	11
High-risk Group 3 Patients	11
Low-risk Group 4 Patients	0
Intermediate-risk Group 4 Patients	7
High-risk Group 4 Patients	1

Values in Participants · Interval/dispersion: Not reported
Group	Value	Spread	Lower	Upper	Comment
Low-risk SHH Patients	2	Not reported	Not reported	Not reported	Not reported
Intermediate-risk SHH Patients	1	Not reported	Not reported	Not reported	Not reported
High-risk SHH Patients	1	Not reported	Not reported	Not reported	Not reported
Intermediate-risk Group 3 Patients	3	Not reported	Not reported	Not reported	Not reported
High-risk Group 3 Patients	4	Not reported	Not reported	Not reported	Not reported
Intermediate-risk Group 4 Patients	0	Not reported	Not reported	Not reported	Not reported
High-risk Group 4 Patients	0	Not reported	Not reported	Not reported	Not reported

chr20q gain/amplification

Analysis denominator · Participants

Group	Source count
Low-risk SHH Patients	23
Intermediate-risk SHH Patients	8
High-risk SHH Patients	11
Low-risk Group 3 Patients	0
Intermediate-risk Group 3 Patients	11
High-risk Group 3 Patients	11
Low-risk Group 4 Patients	0
Intermediate-risk Group 4 Patients	7
High-risk Group 4 Patients	1

Values in Participants · Interval/dispersion: Not reported
Group	Value	Spread	Lower	Upper	Comment
Low-risk SHH Patients	0	Not reported	Not reported	Not reported	Not reported
Intermediate-risk SHH Patients	0	Not reported	Not reported	Not reported	Not reported
High-risk SHH Patients	0	Not reported	Not reported	Not reported	Not reported
Intermediate-risk Group 3 Patients	0	Not reported	Not reported	Not reported	Not reported
High-risk Group 3 Patients	0	Not reported	Not reported	Not reported	Not reported
Intermediate-risk Group 4 Patients	0	Not reported	Not reported	Not reported	Not reported
High-risk Group 4 Patients	0	Not reported	Not reported	Not reported	Not reported

chr20q loss/deletion

Analysis denominator · Participants

Group	Source count
Low-risk SHH Patients	23
Intermediate-risk SHH Patients	8
High-risk SHH Patients	11
Low-risk Group 3 Patients	0
Intermediate-risk Group 3 Patients	11
High-risk Group 3 Patients	11
Low-risk Group 4 Patients	0
Intermediate-risk Group 4 Patients	7
High-risk Group 4 Patients	1

Values in Participants · Interval/dispersion: Not reported
Group	Value	Spread	Lower	Upper	Comment
Low-risk SHH Patients	1	Not reported	Not reported	Not reported	Not reported
Intermediate-risk SHH Patients	0	Not reported	Not reported	Not reported	Not reported
High-risk SHH Patients	1	Not reported	Not reported	Not reported	Not reported
Intermediate-risk Group 3 Patients	3	Not reported	Not reported	Not reported	Not reported
High-risk Group 3 Patients	4	Not reported	Not reported	Not reported	Not reported
Intermediate-risk Group 4 Patients	0	Not reported	Not reported	Not reported	Not reported
High-risk Group 4 Patients	0	Not reported	Not reported	Not reported	Not reported

Complete source fields

classes

categories
measurements
group Id
OG000
value
7
group Id
OG001
value
4
group Id
OG002
value
3
group Id
OG004
value
0
group Id
OG005
value
0
group Id
OG007
value
0
group Id
OG008
value
0
denoms
counts
group Id
OG000
value
23
group Id
OG001
value
8
group Id
OG002
value
11
group Id
OG003
value
0
group Id
OG004
value
12
group Id
OG005
value
11
group Id
OG006
value
0
group Id
OG007
value
8
group Id
OG008
value
2
units
Participants
title
PTCH1 alteration
categories
measurements
group Id
OG000
value
6
group Id
OG001
value
1
group Id
OG002
value
1
group Id
OG004
value
0
group Id
OG005
value
0
group Id
OG007
value
0
group Id
OG008
value
0
denoms
counts
group Id
OG000
value
23
group Id
OG001
value
8
group Id
OG002
value
11
group Id
OG003
value
0
group Id
OG004
value
12
group Id
OG005
value
11
group Id
OG006
value
0
group Id
OG007
value
8
group Id
OG008
value
2
units
Participants
title
SUFU alteration
categories
measurements
group Id
OG000
value
5
group Id
OG001
value
1
group Id
OG002
value
3
group Id
OG004
value
0
group Id
OG005
value
0
group Id
OG007
value
0
group Id
OG008
value
0
denoms
counts
group Id
OG000
value
22
group Id
OG001
value
6
group Id
OG002
value
10
group Id
OG003
value
0
group Id
OG004
value
9
group Id
OG005
value
6
group Id
OG006
value
0
group Id
OG007
value
5
group Id
OG008
value
2
units
Participants
title
KMT2D alteration
categories
measurements
group Id
OG000
value
2
group Id
OG001
value
0
group Id
OG002
value
1
group Id
OG004
value
0
group Id
OG005
value
0
group Id
OG007
value
0
group Id
OG008
value
0
denoms
counts
group Id
OG000
value
22
group Id
OG001
value
6
group Id
OG002
value
10
group Id
OG003
value
0
group Id
OG004
value
9
group Id
OG005
value
6
group Id
OG006
value
0
group Id
OG007
value
5
group Id
OG008
value
1
units
Participants
title
SMO alteration
categories
measurements
group Id
OG000
value
1
group Id
OG001
value
0
group Id
OG002
value
0
group Id
OG004
value
0
group Id
OG005
value
0
group Id
OG007
value
0
group Id
OG008
value
0
denoms
counts
group Id
OG000
value
22
group Id
OG001
value
6
group Id
OG002
value
10
group Id
OG003
value
0
group Id
OG004
value
9
group Id
OG005
value
6
group Id
OG006
value
0
group Id
OG007
value
5
group Id
OG008
value
1
units
Participants
title
BCOR alteration
categories
measurements
group Id
OG000
value
1
group Id
OG001
value
0
group Id
OG002
value
0
group Id
OG004
value
0
group Id
OG005
value
0
group Id
OG007
value
0
group Id
OG008
value
0
denoms
counts
group Id
OG000
value
23
group Id
OG001
value
8
group Id
OG002
value
11
group Id
OG003
value
0
group Id
OG004
value
12
group Id
OG005
value
11
group Id
OG006
value
0
group Id
OG007
value
8
group Id
OG008
value
2
units
Participants
title
PTEN alteration
categories
measurements
group Id
OG000
value
0
group Id
OG001
value
0
group Id
OG002
value
0
group Id
OG004
value
0
group Id
OG005
value
0
group Id
OG007
value
0
group Id
OG008
value
0
denoms
counts
group Id
OG000
value
22
group Id
OG001
value
6
group Id
OG002
value
10
group Id
OG003
value
0
group Id
OG004
value
9
group Id
OG005
value
6
group Id
OG006
value
0
group Id
OG007
value
5
group Id
OG008
value
1
units
Participants
title
BRCA2 alteration
categories
measurements
group Id
OG000
value
0
group Id
OG001
value
0
group Id
OG002
value
0
group Id
OG004
value
0
group Id
OG005
value
0
group Id
OG007
value
0
group Id
OG008
value
0
denoms
counts
group Id
OG000
value
23
group Id
OG001
value
8
group Id
OG002
value
11
group Id
OG003
value
0
group Id
OG004
value
11
group Id
OG005
value
11
group Id
OG006
value
0
group Id
OG007
value
7
group Id
OG008
value
1
units
Participants
title
GLI2 alteration
categories
measurements
group Id
OG000
value
2
group Id
OG001
value
0
group Id
OG002
value
0
group Id
OG004
value
1
group Id
OG005
value
0
group Id
OG007
value
0
group Id
OG008
value
0
denoms
counts
group Id
OG000
value
22
group Id
OG001
value
6
group Id
OG002
value
10
group Id
OG003
value
0
group Id
OG004
value
9
group Id
OG005
value
6
group Id
OG006
value
0
group Id
OG007
value
5
group Id
OG008
value
1
units
Participants
title
SMARCA4 alteration
categories
measurements
group Id
OG000
value
0
group Id
OG001
value
0
group Id
OG002
value
0
group Id
OG004
value
0
group Id
OG005
value
0
group Id
OG007
value
0
group Id
OG008
value
0
denoms
counts
group Id
OG000
value
23
group Id
OG001
value
8
group Id
OG002
value
11
group Id
OG003
value
0
group Id
OG004
value
12
group Id
OG005
value
11
group Id
OG006
value
0
group Id
OG007
value
8
group Id
OG008
value
2
units
Participants
title
TP53 alteration
categories
measurements
group Id
OG000
value
0
group Id
OG001
value
1
group Id
OG002
value
0
group Id
OG004
value
0
group Id
OG005
value
1
group Id
OG007
value
0
group Id
OG008
value
0
denoms
counts
group Id
OG000
value
23
group Id
OG001
value
8
group Id
OG002
value
11
group Id
OG003
value
0
group Id
OG004
value
12
group Id
OG005
value
11
group Id
OG006
value
0
group Id
OG007
value
8
group Id
OG008
value
2
units
Participants
title
MYCN amplification
categories
measurements
group Id
OG000
value
5
group Id
OG001
value
0
group Id
OG002
value
4
group Id
OG004
value
0
group Id
OG005
value
1
group Id
OG007
value
0
group Id
OG008
value
0
denoms
counts
group Id
OG000
value
23
group Id
OG001
value
8
group Id
OG002
value
11
group Id
OG003
value
0
group Id
OG004
value
11
group Id
OG005
value
11
group Id
OG006
value
0
group Id
OG007
value
7
group Id
OG008
value
1
units
Participants
title
chr2p gain/amplification

denoms

counts
group Id
OG000
value
23
group Id
OG001
value
8
group Id
OG002
value
11
group Id
OG003
value
0
group Id
OG004
value
13
group Id
OG005
value
11
group Id
OG006
value
0
group Id
OG007
value
8
group Id
OG008
value
2
units
Participants

description

Alterations included single nucleotide variants (SNPs), amplifications, deletions, translocations, indels, and germline alterations. Cytogenetic information shows gains and losses as specified in the table of measured values.

groups

description
Sonic hedgehog (SHH) medulloblastoma subgroup patients in the low-risk group
id
OG000
title
Low-risk SHH Patients
description
Sonic hedgehog (SHH) medulloblastoma subgroup patients in the intermediate-risk group
id
OG001
title
Intermediate-risk SHH Patients
description
Sonic hedgehog (SHH) medulloblastoma subgroup patients in the high-risk group
id
OG002
title
High-risk SHH Patients
description
Group 3 (G3) medulloblastoma subgroup patients in the low-risk group
id
OG003
title
Low-risk Group 3 Patients
description
Group 3 medulloblastoma subgroup patients in the intermediate-risk group
id
OG004
title
Intermediate-risk Group 3 Patients
description
Group 3 medulloblastoma subgroup patients in the high-risk group
id
OG005
title
High-risk Group 3 Patients
description
Group 4 (G4) medulloblastoma subgroup patients in the low-risk group
id
OG006
title
Low-risk Group 4 Patients
description
Group 4 (G4) medulloblastoma subgroup patients in the intermediate-risk group
id
OG007
title
Intermediate-risk Group 4 Patients
description
Group 4 medulloblastoma subgroup patients in the high-risk group
id
OG008
title
High-risk Group 4 Patients

param Type

COUNT_OF_PARTICIPANTS

population Description

Eligible patients with molecularly confirmed medulloblastoma (n=76) were included in these analyses. Not all patients had data available for each gene.

reporting Status

POSTED

time Frame

Based on samples obtained at the time of initial surgery or repeat surgery prior to treatment

title

Numbers of Patients With Molecular Abnormalities by Tumor Type

type

SECONDARY

unit Of Measure

Participants

Download exact source JSON → · Snapshot ctgov-results-191f4516d4760045304b24a0

Preserved source evidence · Not medical advice