TriangleNCT00416624 · OUTCOME
Mean Hemoglobin Change From Week 1 to Week 16
Results reported by the registry submitting party. Population, time horizon, units and missing values must be read together.
- Measure
- MEAN
- Unit
- g/dL
- Interval / dispersion
- Standard Deviation
- Time frame
- Week 1 and Week 16
What was measured
To compare the effects of the 3 different epoetin alfa dosing schedules and an every-3-weeks darbepoetin alfa schedule. The positive numbers represent hemoglobin increases and negative numbers represent hemoglobin decreases.
Analysis population: All patients that were evaluable per protocol and had hemoglobin data.
Groups in this outcome
Epoetin Alfa - 40k Weekly
Patients receive Epoetin alfa 40,000 units subcutaneously every week for 15 weeks (15 doses)
Epoetin Alfa - 80k Every 3 Weeks
Patients receive Epoetin alfa 80,000 units subcutaneously every 3 weeks for 15 weeks (5 doses)
Epoetin Alfa - 120k Every 3 Weeks
Patients receive Epoetin alfa 120,000 units subcutaneously every 3 weeks for 15 weeks (5 doses)
Darbepoetin Alfa - 500 mcg Every 3 Weeks
Patients receive Darbepoetin alfa 500 micrograms (mcg) subcutaneously every 3 weeks for 15 weeks (5 doses)
| Group | Source count |
|---|---|
| Epoetin Alfa - 40k Weekly | 61 |
| Epoetin Alfa - 80k Every 3 Weeks | 60 |
| Epoetin Alfa - 120k Every 3 Weeks | 58 |
| Darbepoetin Alfa - 500 mcg Every 3 Weeks | 57 |
Reported measurements
Source class 1
| Group | Value | Spread | Lower | Upper | Comment |
|---|---|---|---|---|---|
| Epoetin Alfa - 40k Weekly | 11.0 | 1.03 | Not reported | Not reported | Not reported |
| Epoetin Alfa - 80k Every 3 Weeks | 10.3 | 1.04 | Not reported | Not reported | Not reported |
| Epoetin Alfa - 120k Every 3 Weeks | 10.6 | 0.8 | Not reported | Not reported | Not reported |
| Darbepoetin Alfa - 500 mcg Every 3 Weeks | 10.7 | 0.96 | Not reported | Not reported | Not reported |
Complete source fields
- classes
- categories
- measurements
- group Id
- OG000
- spread
- 1.03
- value
- 11.0
- group Id
- OG001
- spread
- 1.04
- value
- 10.3
- group Id
- OG002
- spread
- 0.8
- value
- 10.6
- group Id
- OG003
- spread
- 0.96
- value
- 10.7
- denoms
- counts
- group Id
- OG000
- value
- 61
- group Id
- OG001
- value
- 60
- group Id
- OG002
- value
- 58
- group Id
- OG003
- value
- 57
- units
- Participants
- description
- To compare the effects of the 3 different epoetin alfa dosing schedules and an every-3-weeks darbepoetin alfa schedule. The positive numbers represent hemoglobin increases and negative numbers represent hemoglobin decreases.
- dispersion Type
- Standard Deviation
- groups
- description
- Patients receive Epoetin alfa 40,000 units subcutaneously every week for 15 weeks (15 doses)
- id
- OG000
- title
- Epoetin Alfa - 40k Weekly
- description
- Patients receive Epoetin alfa 80,000 units subcutaneously every 3 weeks for 15 weeks (5 doses)
- id
- OG001
- title
- Epoetin Alfa - 80k Every 3 Weeks
- description
- Patients receive Epoetin alfa 120,000 units subcutaneously every 3 weeks for 15 weeks (5 doses)
- id
- OG002
- title
- Epoetin Alfa - 120k Every 3 Weeks
- description
- Patients receive Darbepoetin alfa 500 micrograms (mcg) subcutaneously every 3 weeks for 15 weeks (5 doses)
- id
- OG003
- title
- Darbepoetin Alfa - 500 mcg Every 3 Weeks
- param Type
- MEAN
- population Description
- All patients that were evaluable per protocol and had hemoglobin data.
- reporting Status
- POSTED
- time Frame
- Week 1 and Week 16
- title
- Mean Hemoglobin Change From Week 1 to Week 16
- type
- SECONDARY
- unit Of Measure
- g/dL
Download exact source JSON → · Snapshot ctgov-results-25a395029948b04d52b1253f
Preserved source evidence · Not medical advice