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NCT00408005 · OUTCOME

Disease-free Survival (DFS) for Randomized Methotrexate T-ALL Cohort (Arm I + Arm II vs. Arm III + Arm IV)

Combination Chemotherapy in Treating Young Patients With Newly Diagnosed T-Cell Acute Lymphoblastic Leukemia or T-cell Lymphoblastic Lymphoma · Source last updated 2026-06-23

Results reported by the registry submitting party. Population, time horizon, units and missing values must be read together.

Measure
NUMBER
Unit
percent probability
Interval / dispersion
95% Confidence Interval
Time frame
4 years from randomization at the end of induction

What was measured

Disease Free Probability where DFS time is defined as time from randomization end of induction to first event (relapse, second malignant neoplasm, death) or date of last contact for patients who are event-free.

Analysis population: Includes subjects randomized to Capizzi Methotrexate versus High-Dose Methotrexate

Groups in this outcome

ARM I and ARM II (Combination Chemotherapy)

Capizzi Methotrexate (Combined)

ARM III and ARM IV (Combination Chemotherapy)

High-Dose Methotrexate (Combined)

Group identifiers and denominators belong to this outcome only. They may differ in another outcome or in safety reporting.

Analysis denominator · Participants

GroupSource count
ARM I and ARM II (Combination Chemotherapy)519
ARM III and ARM IV (Combination Chemotherapy)512

Reported measurements

Source class 1
Values in percent probability · Interval/dispersion: 95% Confidence Interval
GroupValueSpreadLowerUpperComment
ARM I and ARM II (Combination Chemotherapy)91.45Not reported88.894.1Not reported
ARM III and ARM IV (Combination Chemotherapy)85.78Not reported82.489.1Not reported
Complete source fields
classes
  1. categories
    1. measurements
      1. group Id
        OG000
        lower Limit
        88.8
        upper Limit
        94.1
        value
        91.45
      2. group Id
        OG001
        lower Limit
        82.4
        upper Limit
        89.1
        value
        85.78
denoms
  1. counts
    1. group Id
      OG000
      value
      519
    2. group Id
      OG001
      value
      512
    units
    Participants
description
Disease Free Probability where DFS time is defined as time from randomization end of induction to first event (relapse, second malignant neoplasm, death) or date of last contact for patients who are event-free.
dispersion Type
95% Confidence Interval
groups
  1. description
    Capizzi Methotrexate (Combined)
    id
    OG000
    title
    ARM I and ARM II (Combination Chemotherapy)
  2. description
    High-Dose Methotrexate (Combined)
    id
    OG001
    title
    ARM III and ARM IV (Combination Chemotherapy)
param Type
NUMBER
population Description
Includes subjects randomized to Capizzi Methotrexate versus High-Dose Methotrexate
reporting Status
POSTED
time Frame
4 years from randomization at the end of induction
title
Disease-free Survival (DFS) for Randomized Methotrexate T-ALL Cohort (Arm I + Arm II vs. Arm III + Arm IV)
type
PRIMARY
unit Of Measure
percent probability

Download exact source JSON → · Snapshot ctgov-results-191f4516d4760045304b24a0

Preserved source evidence · Not medical advice