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NCT00392327 · OUTCOME

Metacognition Index (MI) on the Behavior Rating Inventory of Executive Function (BRIEF) at 9+/-3 Months Post Diagnosis for SPNET Patients

Chemotherapy and Radiation Therapy in Treating Young Patients With Newly Diagnosed, Previously Untreated, High-Risk Medulloblastoma/PNET · Source last updated 2026-06-08

Results reported by the registry submitting party. Population, time horizon, units and missing values must be read together.

Measure
MEAN
Unit
T-Score
Interval / dispersion
Standard Deviation
Time frame
6 - 12 months post diagnosis

What was measured

Metacognition index (MI) was measured by BRIEF test. Assessments within the time window, from eligible and evaluable patients are reported. If the patient had disease progression, only the assessments before progression date were reported. The MI is a standard T- score, and it ranges from 0 to 100. The higher score reported suggests a higher level of dysfunction. Mean and standard deviation of MI were calculated and reported.

Analysis population: Eligible SPNET patients are included.

Groups in this outcome

Regimen A (SPNET Patients)

SPNET patients who received regimen A (no carboplatin / no isotretinoin)

Regimen B (SPNET Patients)

SPNET patients who received regimen B (carboplatin / no isotretinoin)

Regimen C (SPNET Patients)

SPNET patients who received regimen C (no carboplatin / isotretinoin)

Regimen D (SPNET Patients)

SPNET patients who received regimen D (carboplatin / isotretinoin)

Group identifiers and denominators belong to this outcome only. They may differ in another outcome or in safety reporting.

Analysis denominator · Participants

GroupSource count
Regimen A (SPNET Patients)4
Regimen B (SPNET Patients)3
Regimen C (SPNET Patients)7
Regimen D (SPNET Patients)4

Reported measurements

Source class 1
Values in T-Score · Interval/dispersion: Standard Deviation
GroupValueSpreadLowerUpperComment
Regimen A (SPNET Patients)53.815.73Not reportedNot reportedNot reported
Regimen B (SPNET Patients)66.71.53Not reportedNot reportedNot reported
Regimen C (SPNET Patients)46.18.28Not reportedNot reportedNot reported
Regimen D (SPNET Patients)64.36.5Not reportedNot reportedNot reported
Complete source fields
classes
  1. categories
    1. measurements
      1. group Id
        OG000
        spread
        15.73
        value
        53.8
      2. group Id
        OG001
        spread
        1.53
        value
        66.7
      3. group Id
        OG002
        spread
        8.28
        value
        46.1
      4. group Id
        OG003
        spread
        6.5
        value
        64.3
denoms
  1. counts
    1. group Id
      OG000
      value
      4
    2. group Id
      OG001
      value
      3
    3. group Id
      OG002
      value
      7
    4. group Id
      OG003
      value
      4
    units
    Participants
description
Metacognition index (MI) was measured by BRIEF test. Assessments within the time window, from eligible and evaluable patients are reported. If the patient had disease progression, only the assessments before progression date were reported. The MI is a standard T- score, and it ranges from 0 to 100. The higher score reported suggests a higher level of dysfunction. Mean and standard deviation of MI were calculated and reported.
dispersion Type
Standard Deviation
groups
  1. description
    SPNET patients who received regimen A (no carboplatin / no isotretinoin)
    id
    OG000
    title
    Regimen A (SPNET Patients)
  2. description
    SPNET patients who received regimen B (carboplatin / no isotretinoin)
    id
    OG001
    title
    Regimen B (SPNET Patients)
  3. description
    SPNET patients who received regimen C (no carboplatin / isotretinoin)
    id
    OG002
    title
    Regimen C (SPNET Patients)
  4. description
    SPNET patients who received regimen D (carboplatin / isotretinoin)
    id
    OG003
    title
    Regimen D (SPNET Patients)
param Type
MEAN
population Description
Eligible SPNET patients are included.
reporting Status
POSTED
time Frame
6 - 12 months post diagnosis
title
Metacognition Index (MI) on the Behavior Rating Inventory of Executive Function (BRIEF) at 9+/-3 Months Post Diagnosis for SPNET Patients
type
SECONDARY
unit Of Measure
T-Score

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Preserved source evidence · Not medical advice