TriangleNCT00387348 · OUTCOME
Change in Hamilton Depression Rating Scale (HAM-D) Scores
Results reported by the registry submitting party. Population, time horizon, units and missing values must be read together.
- Measure
- MEAN
- Unit
- Change in HAM-D scores
- Interval / dispersion
- Standard Deviation
- Time frame
- 4 weeks
What was measured
The change in HAM-D scores was calculated by subtracting the score at 4 weeks from the score at baseline. The HAM-D can have total scores that range from 0 to 50, with higher scores indicating greater depression. Scores over 14 are considered to be in the depressed range.
Analysis population: Participants who had at least 1 follow up HAM-D assessment were included. Two participants died, one without a follow up assessment and one with a HAM-D at 2 weeks. For the participant who had the HAM-D at 2 weeks and then died, the last endpoint was carried forward.
Groups in this outcome
Placebo-Placebo
Participants in this arm were randomized to receive placebo once daily by mouth for the first 4 weeks and placebo once daily by mouth for the second 4 weeks
Placebo-Escitalopram
Participants in this arm were randomized to receive placebo once daily by mouth for the first 4 weeks and escitalopram 10 mg once daily by mouth for the second 4 weeks
Escitalopram-Placebo
Participants in this arm were randomzied to receive escitalopram 10 mg once daily by mouth for the first 4 weeks and placebo once daily by mouth for the second 4 weeks
| Group | Source count |
|---|---|
| Placebo-Placebo | 7 |
| Placebo-Escitalopram | 5 |
| Escitalopram-Placebo | 11 |
Reported measurements
Source class 1
| Group | Value | Spread | Lower | Upper | Comment |
|---|---|---|---|---|---|
| Placebo-Placebo | 6.23 | 8.37 | Not reported | Not reported | Not reported |
| Placebo-Escitalopram | 10.60 | 5.18 | Not reported | Not reported | Not reported |
| Escitalopram-Placebo | 6.45 | 5.18 | Not reported | Not reported | Not reported |
Complete source fields
- classes
- categories
- measurements
- group Id
- OG000
- spread
- 8.37
- value
- 6.23
- group Id
- OG001
- spread
- 5.18
- value
- 10.60
- group Id
- OG002
- spread
- 5.18
- value
- 6.45
- denoms
- counts
- group Id
- OG000
- value
- 7
- group Id
- OG001
- value
- 5
- group Id
- OG002
- value
- 11
- units
- Participants
- description
- The change in HAM-D scores was calculated by subtracting the score at 4 weeks from the score at baseline. The HAM-D can have total scores that range from 0 to 50, with higher scores indicating greater depression. Scores over 14 are considered to be in the depressed range.
- dispersion Type
- Standard Deviation
- groups
- description
- Participants in this arm were randomized to receive placebo once daily by mouth for the first 4 weeks and placebo once daily by mouth for the second 4 weeks
- id
- OG000
- title
- Placebo-Placebo
- description
- Participants in this arm were randomized to receive placebo once daily by mouth for the first 4 weeks and escitalopram 10 mg once daily by mouth for the second 4 weeks
- id
- OG001
- title
- Placebo-Escitalopram
- description
- Participants in this arm were randomzied to receive escitalopram 10 mg once daily by mouth for the first 4 weeks and placebo once daily by mouth for the second 4 weeks
- id
- OG002
- title
- Escitalopram-Placebo
- param Type
- MEAN
- population Description
- Participants who had at least 1 follow up HAM-D assessment were included. Two participants died, one without a follow up assessment and one with a HAM-D at 2 weeks. For the participant who had the HAM-D at 2 weeks and then died, the last endpoint was carried forward.
- reporting Status
- POSTED
- time Frame
- 4 weeks
- title
- Change in Hamilton Depression Rating Scale (HAM-D) Scores
- type
- PRIMARY
- unit Of Measure
- Change in HAM-D scores
Download exact source JSON → · Snapshot ctgov-results-25a395029948b04d52b1253f
Preserved source evidence · Not medical advice