TriangleNCT00387348 · OUTCOME
Depression Response Rate of Escitalopram Oxalate 10 mg Once Daily Compared to Placebo Once Daily for Major Depressive Disorder
Results reported by the registry submitting party. Population, time horizon, units and missing values must be read together.
- Measure
- NUMBER
- Unit
- number of participants with response
- Interval / dispersion
- Not reported
- Time frame
- 4 weeks
What was measured
Response rate was defined as a 50% reduction in the Hamilton Depression Rating Scale (HAM-D) scores over 4 weeks. The HAM-D can have total scores that range from 0 to 50, with higher scores indicating greater depression. Scores over 14 are considered to be in the depressed range.
Analysis population: The efficacy analysis was intent to treat and all randomized participants were analyzed
Groups in this outcome
Placebo-Placebo
Participants in this arm were randomized to receive placebo once daily by mouth for the first 4 weeks and placebo oncedaily by mouth for the second 4 weeks
Placebo-Escitalopram
Participants in this arm were randomized to receive placebo once daily by mouth for the first 4 weeks and escitalopram 10 mg once daily by mouth for the second 4 weeks
Escitalopram-Placebo
Participants in this arm were randomzied to receive escitalopram f10 mg once daily by mouth or the first 4 weeks and placebo once daily by mouth for the second 4 weeks
| Group | Source count |
|---|---|
| Placebo-Placebo | 8 |
| Placebo-Escitalopram | 5 |
| Escitalopram-Placebo | 11 |
Reported measurements
Source class 1
| Group | Value | Spread | Lower | Upper | Comment |
|---|---|---|---|---|---|
| Placebo-Placebo | 3 | 0.52 | Not reported | Not reported | Not reported |
| Placebo-Escitalopram | 1 | 0.47 | Not reported | Not reported | Not reported |
| Escitalopram-Placebo | 6 | 0.52 | Not reported | Not reported | Not reported |
Complete source fields
- classes
- categories
- measurements
- group Id
- OG000
- spread
- 0.52
- value
- 3
- group Id
- OG001
- spread
- 0.47
- value
- 1
- group Id
- OG002
- spread
- 0.52
- value
- 6
- denoms
- counts
- group Id
- OG000
- value
- 8
- group Id
- OG001
- value
- 5
- group Id
- OG002
- value
- 11
- units
- Participants
- description
- Response rate was defined as a 50% reduction in the Hamilton Depression Rating Scale (HAM-D) scores over 4 weeks. The HAM-D can have total scores that range from 0 to 50, with higher scores indicating greater depression. Scores over 14 are considered to be in the depressed range.
- groups
- description
- Participants in this arm were randomized to receive placebo once daily by mouth for the first 4 weeks and placebo oncedaily by mouth for the second 4 weeks
- id
- OG000
- title
- Placebo-Placebo
- description
- Participants in this arm were randomized to receive placebo once daily by mouth for the first 4 weeks and escitalopram 10 mg once daily by mouth for the second 4 weeks
- id
- OG001
- title
- Placebo-Escitalopram
- description
- Participants in this arm were randomzied to receive escitalopram f10 mg once daily by mouth or the first 4 weeks and placebo once daily by mouth for the second 4 weeks
- id
- OG002
- title
- Escitalopram-Placebo
- param Type
- NUMBER
- population Description
- The efficacy analysis was intent to treat and all randomized participants were analyzed
- reporting Status
- POSTED
- time Frame
- 4 weeks
- title
- Depression Response Rate of Escitalopram Oxalate 10 mg Once Daily Compared to Placebo Once Daily for Major Depressive Disorder
- type
- PRIMARY
- unit Of Measure
- number of participants with response
Download exact source JSON → · Snapshot ctgov-results-25a395029948b04d52b1253f
Preserved source evidence · Not medical advice