NCT00370331 · OUTCOME
Summary of Median Platelet Counts
RAISE: Randomized Placebo-Controlled Idiopathic Thrombocytopenic Purpura (ITP) Study With Eltrombopag · Source last updated 2017-04-18
Results reported by the registry submitting party. Population, time horizon, units and missing values must be read together.
- Measure
- MEDIAN
- Unit
- platelets/microliter (ul)
- Interval / dispersion
- Full Range
- Time frame
- Baseline; Day 8 through Week 26 on-treatment; and 1, 2, 4 week follow-up visits
What was measured
Platelet counts were measured by blood draw.
Analysis population: ITT Population
Groups in this outcome
Placebo
Matching placebo tablets taken once a day
Eltrombopag 50 mg QD
Eltrombopag 50 mg oral tablets taken once a day (QD)
Group identifiers and denominators belong to this outcome only. They may differ in another outcome or in safety reporting.
Analysis denominator · Participants
| Group | Source count |
|---|
| Placebo | 62 |
|---|
| Eltrombopag 50 mg QD | 135 |
|---|
Reported measurements
Baseline
Values in platelets/microliter (ul) · Interval/dispersion: Full Range| Group | Value | Spread | Lower | Upper | Comment |
|---|
| Placebo | 16,000 | Not reported | 2000 | 87,000 | Not reported |
|---|
| Eltrombopag 50 mg QD | 16,000 | Not reported | 0 | 78,000 | Not reported |
|---|
Day 8
Values in platelets/microliter (ul) · Interval/dispersion: Full Range| Group | Value | Spread | Lower | Upper | Comment |
|---|
| Placebo | 17,500 | Not reported | 3000 | 354,000 | Not reported |
|---|
| Eltrombopag 50 mg QD | 36,000 | Not reported | 1000 | 593,000 | Not reported |
|---|
Day 15
Values in platelets/microliter (ul) · Interval/dispersion: Full Range| Group | Value | Spread | Lower | Upper | Comment |
|---|
| Placebo | 18,000 | Not reported | 2000 | 214,000 | Not reported |
|---|
| Eltrombopag 50 mg QD | 54,000 | Not reported | 2000 | 750,000 | Not reported |
|---|
Day 22
Values in platelets/microliter (ul) · Interval/dispersion: Full Range| Group | Value | Spread | Lower | Upper | Comment |
|---|
| Placebo | 18,500 | Not reported | 1000 | 271,000 | Not reported |
|---|
| Eltrombopag 50 mg QD | 54,000 | Not reported | 1000 | 507,000 | Not reported |
|---|
Day 29
Values in platelets/microliter (ul) · Interval/dispersion: Full Range| Group | Value | Spread | Lower | Upper | Comment |
|---|
| Placebo | 18,000 | Not reported | 3000 | 313,000 | Not reported |
|---|
| Eltrombopag 50 mg QD | 53,000 | Not reported | 1000 | 400,000 | Not reported |
|---|
Day 36
Values in platelets/microliter (ul) · Interval/dispersion: Full Range| Group | Value | Spread | Lower | Upper | Comment |
|---|
| Placebo | 19,000 | Not reported | 4000 | 297,000 | Not reported |
|---|
| Eltrombopag 50 mg QD | 60,000 | Not reported | 1000 | 952,000 | Not reported |
|---|
Day 43
Values in platelets/microliter (ul) · Interval/dispersion: Full Range| Group | Value | Spread | Lower | Upper | Comment |
|---|
| Placebo | 20,000 | Not reported | 3000 | 275,000 | Not reported |
|---|
| Eltrombopag 50 mg QD | 59,000 | Not reported | 1000 | 545,000 | Not reported |
|---|
Week 10
Values in platelets/microliter (ul) · Interval/dispersion: Full Range| Group | Value | Spread | Lower | Upper | Comment |
|---|
| Placebo | 20,000 | Not reported | 0 | 293,000 | Not reported |
|---|
| Eltrombopag 50 mg QD | 61,500 | Not reported | 1000 | 433,000 | Not reported |
|---|
Week 14
Values in platelets/microliter (ul) · Interval/dispersion: Full Range| Group | Value | Spread | Lower | Upper | Comment |
|---|
| Placebo | 17,500 | Not reported | 1000 | 303,000 | Not reported |
|---|
| Eltrombopag 50 mg QD | 60,000 | Not reported | 1000 | 409,000 | Not reported |
|---|
Week 18
Values in platelets/microliter (ul) · Interval/dispersion: Full Range| Group | Value | Spread | Lower | Upper | Comment |
|---|
| Placebo | 20,500 | Not reported | 2000 | 281,000 | Not reported |
|---|
| Eltrombopag 50 mg QD | 61,000 | Not reported | 3000 | 363,000 | Not reported |
|---|
Week 22
Values in platelets/microliter (ul) · Interval/dispersion: Full Range| Group | Value | Spread | Lower | Upper | Comment |
|---|
| Placebo | 23,000 | Not reported | 1000 | 315,000 | Not reported |
|---|
| Eltrombopag 50 mg QD | 72,000 | Not reported | 3000 | 408,000 | Not reported |
|---|
Week 26
Values in platelets/microliter (ul) · Interval/dispersion: Full Range| Group | Value | Spread | Lower | Upper | Comment |
|---|
| Placebo | 23,000 | Not reported | 2000 | 315,000 | Not reported |
|---|
| Eltrombopag 50 mg QD | 73,500 | Not reported | 1000 | 429,000 | Not reported |
|---|
1 Week Follow-up
Values in platelets/microliter (ul) · Interval/dispersion: Full Range| Group | Value | Spread | Lower | Upper | Comment |
|---|
| Placebo | 19,000 | Not reported | 0 | 323,000 | Not reported |
|---|
| Eltrombopag 50 mg QD | 38,500 | Not reported | 1000 | 409,000 | Not reported |
|---|
2 Week Follow-up
Values in platelets/microliter (ul) · Interval/dispersion: Full Range| Group | Value | Spread | Lower | Upper | Comment |
|---|
| Placebo | 18,000 | Not reported | 1000 | 340,000 | Not reported |
|---|
| Eltrombopag 50 mg QD | 21,000 | Not reported | 1000 | 434,000 | Not reported |
|---|
4 Week Follow-up
Values in platelets/microliter (ul) · Interval/dispersion: Full Range| Group | Value | Spread | Lower | Upper | Comment |
|---|
| Placebo | 18,000 | Not reported | 1000 | 301,000 | Not reported |
|---|
| Eltrombopag 50 mg QD | 24,000 | Not reported | 1000 | 446,000 | Not reported |
|---|
Complete source fields
- classes
- categories
- measurements
- group Id
- OG000
- lower Limit
- 2000
- upper Limit
- 87,000
- value
- 16,000
- group Id
- OG001
- lower Limit
- 0
- upper Limit
- 78,000
- value
- 16,000
- title
- Baseline
- categories
- measurements
- group Id
- OG000
- lower Limit
- 3000
- upper Limit
- 354,000
- value
- 17,500
- group Id
- OG001
- lower Limit
- 1000
- upper Limit
- 593,000
- value
- 36,000
- title
- Day 8
- categories
- measurements
- group Id
- OG000
- lower Limit
- 2000
- upper Limit
- 214,000
- value
- 18,000
- group Id
- OG001
- lower Limit
- 2000
- upper Limit
- 750,000
- value
- 54,000
- title
- Day 15
- categories
- measurements
- group Id
- OG000
- lower Limit
- 1000
- upper Limit
- 271,000
- value
- 18,500
- group Id
- OG001
- lower Limit
- 1000
- upper Limit
- 507,000
- value
- 54,000
- title
- Day 22
- categories
- measurements
- group Id
- OG000
- lower Limit
- 3000
- upper Limit
- 313,000
- value
- 18,000
- group Id
- OG001
- lower Limit
- 1000
- upper Limit
- 400,000
- value
- 53,000
- title
- Day 29
- categories
- measurements
- group Id
- OG000
- lower Limit
- 4000
- upper Limit
- 297,000
- value
- 19,000
- group Id
- OG001
- lower Limit
- 1000
- upper Limit
- 952,000
- value
- 60,000
- title
- Day 36
- categories
- measurements
- group Id
- OG000
- lower Limit
- 3000
- upper Limit
- 275,000
- value
- 20,000
- group Id
- OG001
- lower Limit
- 1000
- upper Limit
- 545,000
- value
- 59,000
- title
- Day 43
- categories
- measurements
- group Id
- OG000
- lower Limit
- 0
- upper Limit
- 293,000
- value
- 20,000
- group Id
- OG001
- lower Limit
- 1000
- upper Limit
- 433,000
- value
- 61,500
- title
- Week 10
- categories
- measurements
- group Id
- OG000
- lower Limit
- 1000
- upper Limit
- 303,000
- value
- 17,500
- group Id
- OG001
- lower Limit
- 1000
- upper Limit
- 409,000
- value
- 60,000
- title
- Week 14
- categories
- measurements
- group Id
- OG000
- lower Limit
- 2000
- upper Limit
- 281,000
- value
- 20,500
- group Id
- OG001
- lower Limit
- 3000
- upper Limit
- 363,000
- value
- 61,000
- title
- Week 18
- categories
- measurements
- group Id
- OG000
- lower Limit
- 1000
- upper Limit
- 315,000
- value
- 23,000
- group Id
- OG001
- lower Limit
- 3000
- upper Limit
- 408,000
- value
- 72,000
- title
- Week 22
- categories
- measurements
- group Id
- OG000
- lower Limit
- 2000
- upper Limit
- 315,000
- value
- 23,000
- group Id
- OG001
- lower Limit
- 1000
- upper Limit
- 429,000
- value
- 73,500
- title
- Week 26
- denoms
- counts
- group Id
- OG000
- value
- 62
- group Id
- OG001
- value
- 135
- units
- Participants
- description
- Platelet counts were measured by blood draw.
- dispersion Type
- Full Range
- groups
- description
- Matching placebo tablets taken once a day
- id
- OG000
- title
- Placebo
- description
- Eltrombopag 50 mg oral tablets taken once a day (QD)
- id
- OG001
- title
- Eltrombopag 50 mg QD
- param Type
- MEDIAN
- population Description
- ITT Population
- reporting Status
- POSTED
- time Frame
- Baseline; Day 8 through Week 26 on-treatment; and 1, 2, 4 week follow-up visits
- title
- Summary of Median Platelet Counts
- type
- SECONDARY
- unit Of Measure
- platelets/microliter (ul)
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