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NCT00356031 · BASELINE

Baseline characteristics

Bevacizumab and Radiation Therapy for Sarcomas · Source last updated 2017-05-19

Results reported by the registry submitting party. Population, time horizon, units and missing values must be read together.

denoms
  1. counts
    1. group Id
      BG000
      value
      20
    units
    Participants
groups
  1. description
    Bevacizumab 5mg/kg, external beam radiation therapy (XRT), surgery, Intraoperative radiation therapy (IORT), and postoperative external beam radiation therapy (Post-op XRT) Bevacizumab: Bevacizumab 5mg/kg given intravenously every 2 weeks for a total of 4 doses Radiation Therapy: External beam radiation given two weeks after the first bevacizumab infusion and delivered 5 days a week at 1.8 Gy per day, over 6 weeks. Total radiation dose is 50.4 Gy. For patients with tumors in the retroperitoneum or pelvis, intraoperative radiation therapy (10-20 Gy) may be given for close or positive margins at the discretion of the radiation oncologist and surgeon. For patients with tumors in the extremity or trunk, post-operative external beam radiation therapy (10-20 Gy) will be given for close or positive margins assuming wound healing is good. Surgery: Surgery is performed 6-7 weeks after completion of neoadjuvant therapy.
    id
    BG000
    title
    Bevacizumab, Radiation, and Surgery
measures
  1. classes
    1. categories
      1. measurements
        1. group Id
          BG000
          value
          0
        title
        <=18 years
      2. measurements
        1. group Id
          BG000
          value
          16
        title
        Between 18 and 65 years
      3. measurements
        1. group Id
          BG000
          value
          4
        title
        >=65 years
    param Type
    COUNT_OF_PARTICIPANTS
    title
    Age, Categorical
    unit Of Measure
    Participants
  2. classes
    1. categories
      1. measurements
        1. group Id
          BG000
          spread
          13
          value
          54
    dispersion Type
    STANDARD_DEVIATION
    param Type
    MEAN
    title
    Age, Continuous
    unit Of Measure
    years
  3. classes
    1. categories
      1. measurements
        1. group Id
          BG000
          value
          7
        title
        Female
      2. measurements
        1. group Id
          BG000
          value
          13
        title
        Male
    param Type
    COUNT_OF_PARTICIPANTS
    title
    Sex: Female, Male
    unit Of Measure
    Participants
  4. classes
    1. categories
      1. measurements
        1. group Id
          BG000
          value
          20
      title
      United States
    param Type
    NUMBER
    title
    Region of Enrollment
    unit Of Measure
    participants
  5. classes
    1. categories
      1. measurements
        1. group Id
          BG000
          value
          8
      title
      Fibroblastic
    2. categories
      1. measurements
        1. group Id
          BG000
          value
          6
      title
      Liposarcoma
    3. categories
      1. measurements
        1. group Id
          BG000
          value
          4
      title
      Leiomyosarcoma
    4. categories
      1. measurements
        1. group Id
          BG000
          value
          1
      title
      Fibroblastic Osteosarcoma
    5. categories
      1. measurements
        1. group Id
          BG000
          value
          1
      title
      Not Otherwise Specified
    param Type
    COUNT_OF_PARTICIPANTS
    title
    Sarcoma Histology
    unit Of Measure
    Participants
  6. classes
    1. categories
      1. measurements
        1. group Id
          BG000
          value
          2
      title
      Low
    2. categories
      1. measurements
        1. group Id
          BG000
          value
          8
      title
      Intermediate
    3. categories
      1. measurements
        1. group Id
          BG000
          value
          10
      title
      High
    param Type
    COUNT_OF_PARTICIPANTS
    title
    Sarcoma Grade
    unit Of Measure
    Participants
  7. classes
    1. categories
      1. measurements
        1. group Id
          BG000
          lower Limit
          5
          upper Limit
          20.2
          value
          8.25
    dispersion Type
    FULL_RANGE
    param Type
    MEDIAN
    title
    Median Sarcoma Size
    unit Of Measure
    Centimeters (cm)
  8. classes
    1. categories
      1. measurements
        1. group Id
          BG000
          value
          13
      title
      Extremity
    2. categories
      1. measurements
        1. group Id
          BG000
          value
          1
      title
      Trunk
    3. categories
      1. measurements
        1. group Id
          BG000
          value
          6
      title
      retroperitoneal/pelvis tumors
    param Type
    COUNT_OF_PARTICIPANTS
    title
    Sarcoma Location
    unit Of Measure
    Participants
Complete source fields
denoms
  1. counts
    1. group Id
      BG000
      value
      20
    units
    Participants
groups
  1. description
    Bevacizumab 5mg/kg, external beam radiation therapy (XRT), surgery, Intraoperative radiation therapy (IORT), and postoperative external beam radiation therapy (Post-op XRT) Bevacizumab: Bevacizumab 5mg/kg given intravenously every 2 weeks for a total of 4 doses Radiation Therapy: External beam radiation given two weeks after the first bevacizumab infusion and delivered 5 days a week at 1.8 Gy per day, over 6 weeks. Total radiation dose is 50.4 Gy. For patients with tumors in the retroperitoneum or pelvis, intraoperative radiation therapy (10-20 Gy) may be given for close or positive margins at the discretion of the radiation oncologist and surgeon. For patients with tumors in the extremity or trunk, post-operative external beam radiation therapy (10-20 Gy) will be given for close or positive margins assuming wound healing is good. Surgery: Surgery is performed 6-7 weeks after completion of neoadjuvant therapy.
    id
    BG000
    title
    Bevacizumab, Radiation, and Surgery
measures
  1. classes
    1. categories
      1. measurements
        1. group Id
          BG000
          value
          0
        title
        <=18 years
      2. measurements
        1. group Id
          BG000
          value
          16
        title
        Between 18 and 65 years
      3. measurements
        1. group Id
          BG000
          value
          4
        title
        >=65 years
    param Type
    COUNT_OF_PARTICIPANTS
    title
    Age, Categorical
    unit Of Measure
    Participants
  2. classes
    1. categories
      1. measurements
        1. group Id
          BG000
          spread
          13
          value
          54
    dispersion Type
    STANDARD_DEVIATION
    param Type
    MEAN
    title
    Age, Continuous
    unit Of Measure
    years
  3. classes
    1. categories
      1. measurements
        1. group Id
          BG000
          value
          7
        title
        Female
      2. measurements
        1. group Id
          BG000
          value
          13
        title
        Male
    param Type
    COUNT_OF_PARTICIPANTS
    title
    Sex: Female, Male
    unit Of Measure
    Participants
  4. classes
    1. categories
      1. measurements
        1. group Id
          BG000
          value
          20
      title
      United States
    param Type
    NUMBER
    title
    Region of Enrollment
    unit Of Measure
    participants
  5. classes
    1. categories
      1. measurements
        1. group Id
          BG000
          value
          8
      title
      Fibroblastic
    2. categories
      1. measurements
        1. group Id
          BG000
          value
          6
      title
      Liposarcoma
    3. categories
      1. measurements
        1. group Id
          BG000
          value
          4
      title
      Leiomyosarcoma
    4. categories
      1. measurements
        1. group Id
          BG000
          value
          1
      title
      Fibroblastic Osteosarcoma
    5. categories
      1. measurements
        1. group Id
          BG000
          value
          1
      title
      Not Otherwise Specified
    param Type
    COUNT_OF_PARTICIPANTS
    title
    Sarcoma Histology
    unit Of Measure
    Participants
  6. classes
    1. categories
      1. measurements
        1. group Id
          BG000
          value
          2
      title
      Low
    2. categories
      1. measurements
        1. group Id
          BG000
          value
          8
      title
      Intermediate
    3. categories
      1. measurements
        1. group Id
          BG000
          value
          10
      title
      High
    param Type
    COUNT_OF_PARTICIPANTS
    title
    Sarcoma Grade
    unit Of Measure
    Participants
  7. classes
    1. categories
      1. measurements
        1. group Id
          BG000
          lower Limit
          5
          upper Limit
          20.2
          value
          8.25
    dispersion Type
    FULL_RANGE
    param Type
    MEDIAN
    title
    Median Sarcoma Size
    unit Of Measure
    Centimeters (cm)
  8. classes
    1. categories
      1. measurements
        1. group Id
          BG000
          value
          13
      title
      Extremity
    2. categories
      1. measurements
        1. group Id
          BG000
          value
          1
      title
      Trunk
    3. categories
      1. measurements
        1. group Id
          BG000
          value
          6
      title
      retroperitoneal/pelvis tumors
    param Type
    COUNT_OF_PARTICIPANTS
    title
    Sarcoma Location
    unit Of Measure
    Participants

Download exact source JSON → · Snapshot ctgov-results-25a395029948b04d52b1253f

Preserved source evidence · Not medical advice