Baseline characteristics

EXTEND (Eltrombopag Extended Dosing Study) · Source last updated 2017-04-17

Results reported by the registry submitting party. Population, time horizon, units and missing values must be read together.

denoms

1. counts

   1. group Id

      BG000

      value

      302

   units

   Participants

groups

1. description

   Open-label eltrombopag was supplied in 25, 50, 75 mg tablets. All subjects started at 50mg once daily and dose was increased or decreased based on platelet count (target range 50-200Gi/L). Alternate days and interruption of dosing was permitted to maintain target range of platelet count. Doses could range from 25 to 75mg. Subjects could remain on treatment up to 2 years.

   id

   BG000

   title

   Eltrombopag

measures

1. classes

   1. categories

      1. measurements

         1. group Id

            BG000

            spread

            15.61

            value

            48.9

   dispersion Type

   STANDARD_DEVIATION

   param Type

   MEAN

   title

   Age, Continuous

   unit Of Measure

   Years

2. classes

   1. categories

      1. measurements

         1. group Id

            BG000

            value

            201

         title

         Female

      2. measurements

         1. group Id

            BG000

            value

            101

         title

         Male

   param Type

   COUNT_OF_PARTICIPANTS

   title

   Sex: Female, Male

   unit Of Measure

   Participants

3. classes

   1. categories

      1. measurements

         1. group Id

            BG000

            value

            101

      title

      Yes

   2. categories

      1. measurements

         1. group Id

            BG000

            value

            201

      title

      No

   param Type

   NUMBER

   title

   Concomitant ITP Medication at Baseline

   unit Of Measure

   Participant

4. classes

   1. categories

      1. measurements

         1. group Id

            BG000

            value

            115

      title

      Yes

   2. categories

      1. measurements

         1. group Id

            BG000

            value

            187

      title

      No

   param Type

   NUMBER

   title

   Splenectomy Status at Baseline

   unit Of Measure

   Participants

5. classes

   1. categories

      1. measurements

         1. group Id

            BG000

            value

            211

      title

      <30 Gi/L

   2. categories

      1. measurements

         1. group Id

            BG000

            value

            52

      title

      30 - 50 Gi/L

   3. categories

      1. measurements

         1. group Id

            BG000

            value

            39

      title

      > 50 Gi/L

   param Type

   NUMBER

   title

   Baseline Platelet Count

   unit Of Measure

   Participants

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Preserved source evidence · Not medical advice