NCT00346164 · OUTCOME

Overall Survival Probability Extent of Resection of the Primary Tumor

Observation, Radiation Therapy, Combination Chemotherapy, and/or Surgery in Treating Young Patients With Soft Tissue Sarcoma · Source last updated 2022-04-28

Results reported by the registry submitting party. Population, time horizon, units and missing values must be read together.

Measure: NUMBER
Unit: Probability
Interval / dispersion: 95% Confidence Interval
Time frame: 5 years

What was measured

Probability of survival after 5 years since enrollment.

Analysis population: 94 participants were excluded because of ineligibility, incorrect treatment, or absence of evaluation for tumor invasiveness and histologic grade.

Groups in this outcome

Less Than Total Resection

Not reported

Negative Margins

Not reported

Positive Margins

Not reported

Group identifiers and denominators belong to this outcome only. They may differ in another outcome or in safety reporting.

Analysis denominator · Participants

Group	Source count
Less Than Total Resection	163
Negative Margins	247
Positive Margins	84

Reported measurements

Source class 1

Values in Probability · Interval/dispersion: 95% Confidence Interval
Group	Value	Spread	Lower	Upper	Comment
Less Than Total Resection	0.5975	Not reported	0.4913	0.7036	Not reported
Negative Margins	0.9353	Not reported	0.8923	0.9782	Not reported
Positive Margins	0.7764	Not reported	0.6565	0.8963	Not reported

Source statistical analyses

Group order, estimate direction, methods and comments are retained. No treatment ranking is inferred.

group Description
The Cox proportional hazards model was used to evaluate prognostic impact of the resection extent of the primary tumor (less than total resection; margin -; margin +) after accounting for the effects of site of the primary tumor (body wall; extremity; head/neck; visceral), disease extent (non-metastatic; metastatic), tumor size (\<=5cm; \>5cm), tumor depth (deep; superficial), tumor invasiveness (invasive; non-invasive), and histologic (POG) grade.
group Ids
OG000
OG001
OG002
non Inferiority Type
OTHER
p Value
0.0096
statistical Method
Regression, Cox

Complete source fields

analyses

group Description
The Cox proportional hazards model was used to evaluate prognostic impact of the resection extent of the primary tumor (less than total resection; margin -; margin +) after accounting for the effects of site of the primary tumor (body wall; extremity; head/neck; visceral), disease extent (non-metastatic; metastatic), tumor size (\<=5cm; \>5cm), tumor depth (deep; superficial), tumor invasiveness (invasive; non-invasive), and histologic (POG) grade.
group Ids
OG000
OG001
OG002
non Inferiority Type
OTHER
p Value
0.0096
statistical Method
Regression, Cox

classes

categories
measurements
group Id
OG000
lower Limit
0.4913
upper Limit
0.7036
value
0.5975
group Id
OG001
lower Limit
0.8923
upper Limit
0.9782
value
0.9353
group Id
OG002
lower Limit
0.6565
upper Limit
0.8963
value
0.7764

denoms

counts
group Id
OG000
value
163
group Id
OG001
value
247
group Id
OG002
value
84
units
Participants

description

Probability of survival after 5 years since enrollment.

dispersion Type

95% Confidence Interval

groups

id
OG000
title
Less Than Total Resection
id
OG001
title
Negative Margins
id
OG002
title
Positive Margins

param Type

NUMBER

population Description

94 participants were excluded because of ineligibility, incorrect treatment, or absence of evaluation for tumor invasiveness and histologic grade.

reporting Status

POSTED

time Frame

5 years

title

Overall Survival Probability Extent of Resection of the Primary Tumor

type

SECONDARY

unit Of Measure

Probability

Download exact source JSON → · Snapshot ctgov-results-191f4516d4760045304b24a0

Preserved source evidence · Not medical advice