NCT00346164 · OUTCOME

Event Free Survival Probability Histologic Grade

Observation, Radiation Therapy, Combination Chemotherapy, and/or Surgery in Treating Young Patients With Soft Tissue Sarcoma · Source last updated 2022-04-28

Results reported by the registry submitting party. Population, time horizon, units and missing values must be read together.

Measure: NUMBER
Unit: Probability
Interval / dispersion: 95% Confidence Interval
Time frame: 5 years

What was measured

Probability of no relapse, secondary malignancy or death after 5 years since enrollment

Analysis population: 94 participants were excluded because of ineligibility, incorrect treatment, or absence of evaluation for tumor invasiveness and histologic grade.

Groups in this outcome

Histologic Grade 1

Not reported

Histologic Grade 2

Not reported

Histologic Grade 3

Not reported

Group identifiers and denominators belong to this outcome only. They may differ in another outcome or in safety reporting.

Analysis denominator · Participants

Group	Source count
Histologic Grade 1	60
Histologic Grade 2	79
Histologic Grade 3	355

Reported measurements

Source class 1

Values in Probability · Interval/dispersion: 95% Confidence Interval
Group	Value	Spread	Lower	Upper	Comment
Histologic Grade 1	0.9636	Not reported	0.8943	1.0000	Not reported
Histologic Grade 2	0.8505	Not reported	0.7382	0.9627	Not reported
Histologic Grade 3	0.6136	Not reported	0.5442	0.6831	Not reported

Source statistical analyses

Group order, estimate direction, methods and comments are retained. No treatment ranking is inferred.

group Description
The Cox proportional hazards model was used to evaluate prognostic impact of histologic (POG) grade after accounting for the effects of disease extent (non-metastatic; metastatic), site of the primary tumor (body wall; extremity; head/neck; visceral), tumor size (\<=5cm; \>5cm), tumor depth (deep; superficial), tumor invasiveness (invasive; non-invasive), and extent of resection of the primary tumor (less than total resection; margin -; margin +) .
group Ids
OG000
OG001
OG002
non Inferiority Type
OTHER
p Value
0.0049
statistical Method
Regression, Cox

Complete source fields

analyses

group Description
The Cox proportional hazards model was used to evaluate prognostic impact of histologic (POG) grade after accounting for the effects of disease extent (non-metastatic; metastatic), site of the primary tumor (body wall; extremity; head/neck; visceral), tumor size (\<=5cm; \>5cm), tumor depth (deep; superficial), tumor invasiveness (invasive; non-invasive), and extent of resection of the primary tumor (less than total resection; margin -; margin +) .
group Ids
OG000
OG001
OG002
non Inferiority Type
OTHER
p Value
0.0049
statistical Method
Regression, Cox

classes

categories
measurements
group Id
OG000
lower Limit
0.8943
upper Limit
1.0000
value
0.9636
group Id
OG001
lower Limit
0.7382
upper Limit
0.9627
value
0.8505
group Id
OG002
lower Limit
0.5442
upper Limit
0.6831
value
0.6136

denoms

counts
group Id
OG000
value
60
group Id
OG001
value
79
group Id
OG002
value
355
units
Participants

description

Probability of no relapse, secondary malignancy or death after 5 years since enrollment

dispersion Type

95% Confidence Interval

groups

id
OG000
title
Histologic Grade 1
id
OG001
title
Histologic Grade 2
id
OG002
title
Histologic Grade 3

param Type

NUMBER

population Description

94 participants were excluded because of ineligibility, incorrect treatment, or absence of evaluation for tumor invasiveness and histologic grade.

reporting Status

POSTED

time Frame

5 years

title

Event Free Survival Probability Histologic Grade

type

SECONDARY

unit Of Measure

Probability

Download exact source JSON → · Snapshot ctgov-results-191f4516d4760045304b24a0

Preserved source evidence · Not medical advice