Baseline characteristics

Study Evaluating AMD3100 for Transplantation of Sibling Donor Stem Cells in Patients With Hematological Malignancies · Source last updated 2017-06-06

Results reported by the registry submitting party. Population, time horizon, units and missing values must be read together.

denoms

1. counts

   1. group Id

      BG000

      value

      25

   2. group Id

      BG001

      value

      46

   3. group Id

      BG002

      value

      21

   4. group Id

      BG003

      value

      92

   units

   Participants

groups

1. description

   * Day 1: Mobilization with 240 mcg/kg SC AMD3100 and leukopheresis * If PBSC collected are not adequate, then donor will again be mobilized with AMD3100 and have leukopheresis collection on day 3.

   id

   BG000

   title

   Subcutaneous (SC) Treatment Plan - Donor

2. description

   * Conditioning Regimen * Cyclophosphamide 60mg/kg/day on Days -3 and -2 * TBI 550cGy on Day -1 * GVHD prophylaxis \*Cyclosporin 3.0mg/kg/day beginning on Day -1 then tapered through Day +100 * PBSC transplant on Day 0

   id

   BG001

   title

   Recipients

3. description

   * Day -3: Mobilization with 80-480 mcg/kg/day IV AMD3100 and PK analysis * Day 1: Mobilization with 240 mcg/kg/day SC AMD3100 and leukopheresis * If PBSC collected are not adequate, then donor will again be mobilized with AMD3100 and have leukopheresis collection on day 3.

   id

   BG002

   title

   Intravenous (IV) Treatment Plan - Donor

4. description

   Total of all reporting groups

   id

   BG003

   title

   Total

measures

1. classes

   1. categories

      1. measurements

         1. group Id

            BG000

            lower Limit

            24

            upper Limit

            66

            value

            54

         2. group Id

            BG001

            lower Limit

            23

            upper Limit

            66

            value

            53

         3. group Id

            BG002

            lower Limit

            21

            upper Limit

            67

            value

            51

         4. group Id

            BG003

            lower Limit

            21

            upper Limit

            67

            value

            52

   dispersion Type

   FULL_RANGE

   param Type

   MEDIAN

   title

   Age, Continuous

   unit Of Measure

   years

2. classes

   1. categories

      1. measurements

         1. group Id

            BG000

            value

            5

         2. group Id

            BG001

            value

            26

         3. group Id

            BG002

            value

            8

         4. group Id

            BG003

            value

            39

         title

         Female

      2. measurements

         1. group Id

            BG000

            value

            20

         2. group Id

            BG001

            value

            20

         3. group Id

            BG002

            value

            13

         4. group Id

            BG003

            value

            53

         title

         Male

   param Type

   COUNT_OF_PARTICIPANTS

   title

   Sex: Female, Male

   unit Of Measure

   Participants

3. classes

   1. categories

      1. measurements

         1. group Id

            BG000

            value

            25

         2. group Id

            BG001

            value

            46

         3. group Id

            BG002

            value

            21

         4. group Id

            BG003

            value

            92

      title

      United States

   param Type

   NUMBER

   title

   Region of Enrollment

   unit Of Measure

   participants

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Preserved source evidence · Not medical advice