TriangleNCT00134017 · OUTCOME
Percentage of Participants Who Develop Acute Graft-versus-host Disease (GVHD)
Results reported by the registry submitting party. Population, time horizon, units and missing values must be read together.
- Measure
- COUNT_OF_PARTICIPANTS
- Unit
- Participants
- Interval / dispersion
- Not reported
- Time frame
- Day 100
What was measured
Percentage of participants who developed grades II-IV and grades III-IV acute GVHD. Acute GVHD is defined by the Przepiorka criteria, which stages the degree of organ involvement in the skin, liver, and gastrointestinal (GI) tract, based on severity, with Stage 1+ being least severe and stage 4+ being the most severe. Grading of acute GVHD is as follows: Grade I (skin involvement stages 1+ to 2+, with no liver or GI involvement), Grade II (skin involvement stages 1+ to 3+, liver 1+, GI tract 1+), Grade III (skin involvement stages 2+ to 3+, liver 1+, GI tract 2+ to 4+), Grade IV (skin involvement stages 4+, Liver 4+).
Analysis population: The study data was analyzed early after 117 participants had been treated. This was done in order to publish the data and establish a new local standard of care at our institution. GVHD data was collected on 15 additional participants for a total of 132. GVHD data was not collected on the remaining 10 participants.
Groups in this outcome
Bone Marrow Transplant
Myeloablative bone marrow transplant with a busulfan (Bu), cyclophosphamide (Cy), preparative regimen and post-transplant cyclophosphamide (PTCy) as GVHD prophylaxis.
| Group | Source count |
|---|---|
| Bone Marrow Transplant | 132 |
Reported measurements
Grades II-IV acute GVHD
| Group | Value | Spread | Lower | Upper | Comment |
|---|---|---|---|---|---|
| Bone Marrow Transplant | 49 | Not reported | Not reported | Not reported | Not reported |
Grades III-IV acute GVHD
| Group | Value | Spread | Lower | Upper | Comment |
|---|---|---|---|---|---|
| Bone Marrow Transplant | 10 | Not reported | Not reported | Not reported | Not reported |
Complete source fields
- classes
- categories
- measurements
- group Id
- OG000
- value
- 49
- title
- Grades II-IV acute GVHD
- categories
- measurements
- group Id
- OG000
- value
- 10
- title
- Grades III-IV acute GVHD
- denoms
- counts
- group Id
- OG000
- value
- 132
- units
- Participants
- description
- Percentage of participants who developed grades II-IV and grades III-IV acute GVHD. Acute GVHD is defined by the Przepiorka criteria, which stages the degree of organ involvement in the skin, liver, and gastrointestinal (GI) tract, based on severity, with Stage 1+ being least severe and stage 4+ being the most severe. Grading of acute GVHD is as follows: Grade I (skin involvement stages 1+ to 2+, with no liver or GI involvement), Grade II (skin involvement stages 1+ to 3+, liver 1+, GI tract 1+), Grade III (skin involvement stages 2+ to 3+, liver 1+, GI tract 2+ to 4+), Grade IV (skin involvement stages 4+, Liver 4+).
- groups
- description
- Myeloablative bone marrow transplant with a busulfan (Bu), cyclophosphamide (Cy), preparative regimen and post-transplant cyclophosphamide (PTCy) as GVHD prophylaxis.
- id
- OG000
- title
- Bone Marrow Transplant
- param Type
- COUNT_OF_PARTICIPANTS
- population Description
- The study data was analyzed early after 117 participants had been treated. This was done in order to publish the data and establish a new local standard of care at our institution. GVHD data was collected on 15 additional participants for a total of 132. GVHD data was not collected on the remaining 10 participants.
- reporting Status
- POSTED
- time Frame
- Day 100
- title
- Percentage of Participants Who Develop Acute Graft-versus-host Disease (GVHD)
- type
- PRIMARY
- unit Of Measure
- Participants
Download exact source JSON → · Snapshot ctgov-results-25a395029948b04d52b1253f
Preserved source evidence · Not medical advice