Baseline characteristics

Treatment of Patients With Newly Diagnosed Medulloblastoma, Supratentorial Primitive Neuroectodermal Tumor, or Atypical Teratoid Rhabdoid Tumor · Source last updated 2024-02-08

Results reported by the registry submitting party. Population, time horizon, units and missing values must be read together.

denoms

1. counts

   1. group Id

      BG000

      value

      269

   2. group Id

      BG001

      value

      144

   3. group Id

      BG002

      value

      413

   units

   Participants

groups

1. description

   Participants assigned to the average-risk arm had localized tumor without overt evidence of invasion beyond the posterior fossa (or supratentorial compartment for PNET's/ATRT). Participants with T4 disease met the following criteria: gross total resection defined as residual tumor or imaging abnormality whose size was \<1.5 cm\^2 on postoperative CT or MR images, no evidence of CNS or extraneural metastasis, and brain stem invasion by the tumor in the absence of imaging evidence of residual tumor (tumor size \<1.5 cm\^2).

   id

   BG000

   title

   Average-Risk Group

2. description

   Participants assigned to the high-risk arm were determined to have the presence of metastatic disease within the neuraxis (i.e., evidence of subarachnoid dissemination), OR presence of residual disease (≥1.5 cm\^2) at the primary site after surgery.

   id

   BG001

   title

   High-Risk Group

3. description

   Total of all reporting groups

   id

   BG002

   title

   Total

measures

1. classes

   1. categories

      1. measurements

         1. group Id

            BG000

            spread

            4.08

            value

            9.15

         2. group Id

            BG001

            spread

            3.93

            value

            8.66

         3. group Id

            BG002

            spread

            4.03

            value

            8.98

   dispersion Type

   STANDARD_DEVIATION

   param Type

   MEAN

   title

   Age, Continuous

   unit Of Measure

   Years

2. classes

   1. categories

      1. measurements

         1. group Id

            BG000

            lower Limit

            3.06

            upper Limit

            21.56

            value

            8.42

         2. group Id

            BG001

            lower Limit

            3.13

            upper Limit

            20.43

            value

            7.87

         3. group Id

            BG002

            lower Limit

            3.06

            upper Limit

            21.56

            value

            8.33

   dispersion Type

   FULL_RANGE

   param Type

   MEDIAN

   title

   Age, Continuous

   unit Of Measure

   years

3. classes

   1. categories

      1. measurements

         1. group Id

            BG000

            value

            105

         2. group Id

            BG001

            value

            56

         3. group Id

            BG002

            value

            161

         title

         Female

      2. measurements

         1. group Id

            BG000

            value

            164

         2. group Id

            BG001

            value

            88

         3. group Id

            BG002

            value

            252

         title

         Male

   param Type

   COUNT_OF_PARTICIPANTS

   title

   Sex: Female, Male

   unit Of Measure

   Participants

population Description

Participants had a diagnosis of medulloblastoma, supratentorial primitive neuroectodermal tumor (PNET), PNET variants (ependymoblastoma, pineoblastoma, CNS neuroblastoma), or atypical teratoid rhabdoid tumor (ATRT).

Download exact source JSON → · Snapshot ctgov-results-191f4516d4760045304b24a0

Preserved source evidence · Not medical advice