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NCT00047320 · FLOW

Participant flow

Neoadjuvant Chemotherapy With or Without Second-Look Surgery Followed by Radiation Therapy With or Without Peripheral Stem Cell Transplantation in Treating Patients With Intracranial Germ Cell Tumors · Source last updated 2018-02-14

Results reported by the registry submitting party. Population, time horizon, units and missing values must be read together.

groups
  1. description
    Patients will receive 6 cycles of Induction chemotherapy consisting of carboplatin and etoposide (Cycles 1, 3, and 5) alternating with ifosfamide and etoposide (Cycles 2, 4, and 6). The entire length of Induction is 18 weeks unless delay occurs due to myelosuppression or unanticipated toxicity. Each cycle of Induction will begin when ANC \> 750/L and platelets \> 75,000/L and when off filgrastim (G-CSF) for at least 48 hours. Following the Induction phase (weeks 0-18) those patient in CR will undergo radiation therapy. carboplatin: Given IV etoposide: Given IV ifosfamide: Given IV radiation therapy: craniospinal irradiation
    id
    FG000
    title
    Radiation Therapy (CR From Induction)
periods
  1. drop Withdraws
    1. reasons
      1. group Id
        FG000
        num Subjects
        8
      type
      Lack of Efficacy
    2. reasons
      1. group Id
        FG000
        num Subjects
        1
      type
      Lost to Follow-up
    3. reasons
      1. group Id
        FG000
        num Subjects
        8
      type
      Physician Decision
    4. reasons
      1. group Id
        FG000
        num Subjects
        9
      type
      Withdrawal by Subject
    5. reasons
      1. group Id
        FG000
        num Subjects
        2
      type
      Ineligible
    milestones
    1. achievements
      1. group Id
        FG000
        num Subjects
        104
      type
      STARTED
    2. achievements
      1. group Id
        FG000
        num Subjects
        76
      type
      COMPLETED
    3. achievements
      1. group Id
        FG000
        num Subjects
        28
      type
      NOT COMPLETED
    title
    Overall Study
Complete source fields
groups
  1. description
    Patients will receive 6 cycles of Induction chemotherapy consisting of carboplatin and etoposide (Cycles 1, 3, and 5) alternating with ifosfamide and etoposide (Cycles 2, 4, and 6). The entire length of Induction is 18 weeks unless delay occurs due to myelosuppression or unanticipated toxicity. Each cycle of Induction will begin when ANC \> 750/L and platelets \> 75,000/L and when off filgrastim (G-CSF) for at least 48 hours. Following the Induction phase (weeks 0-18) those patient in CR will undergo radiation therapy. carboplatin: Given IV etoposide: Given IV ifosfamide: Given IV radiation therapy: craniospinal irradiation
    id
    FG000
    title
    Radiation Therapy (CR From Induction)
periods
  1. drop Withdraws
    1. reasons
      1. group Id
        FG000
        num Subjects
        8
      type
      Lack of Efficacy
    2. reasons
      1. group Id
        FG000
        num Subjects
        1
      type
      Lost to Follow-up
    3. reasons
      1. group Id
        FG000
        num Subjects
        8
      type
      Physician Decision
    4. reasons
      1. group Id
        FG000
        num Subjects
        9
      type
      Withdrawal by Subject
    5. reasons
      1. group Id
        FG000
        num Subjects
        2
      type
      Ineligible
    milestones
    1. achievements
      1. group Id
        FG000
        num Subjects
        104
      type
      STARTED
    2. achievements
      1. group Id
        FG000
        num Subjects
        76
      type
      COMPLETED
    3. achievements
      1. group Id
        FG000
        num Subjects
        28
      type
      NOT COMPLETED
    title
    Overall Study

Download exact source JSON → · Snapshot ctgov-results-191f4516d4760045304b24a0

Preserved source evidence · Not medical advice