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DISEASE & TREATMENT SETTING

Docetaxel: locally advanced Squamous Cell Carcinoma

Source-derived catalogue. This is not a treatment recommendation or a personalised trial match.

Exact scope

1.5 Head and Neck Cancer Docetaxel Injection in combination with cisplatin and fluorouracil is indicated for the induction treatment of patients with locally advanced squamous cell carcinoma of the head and neck (SCCHN).

Broader topic: Squamous Cell Carcinoma

Source population
Not part of this definition
Disease extent
locally-advanced
Treatment line
Not part of this definition
Stage
Not part of this definition
Resectability
Not part of this definition
Biomarkers, prior therapy and derivation
molecular
    prior therapy
      derivation status
      source-attested
      derivation note
      Scoped from the FDA approved indication for Docetaxel (product label). Only dimensions stated in that wording are part of this definition.
      source wording
      1.5 Head and Neck Cancer Docetaxel Injection in combination with cisplatin and fluorouracil is indicated for the induction treatment of patients with locally advanced squamous cell carcinoma of the head and neck (SCCHN).

      Study evidence for this setting

      48 linked studies · Applicability is a draft source assessment, not a determination of your eligibility.

      NCT00112905 · Registry condition search · Scope: unclear

      Sorafenib in Treating Patients With Regional or Metastatic Cancer of the Urothelium

      4 outcome links · 1 safety-group records · 0 quality-of-life measures

      →

      NCT00407485 · Registry condition search · Scope: unclear

      VEGF Trap in Treating Patients With Recurrent, Locally Advanced, or Metastatic Cancer of the Urothelium

      2 outcome links · 1 safety-group records · 0 quality-of-life measures

      →

      NCT00410826 · Registry condition search · Scope: unclear

      Cisplatin and Radiation Therapy With or Without Erlotinib Hydrochloride in Treating Patients With Stage III or Stage IV Head and Neck Cancer

      3 outcome links · 2 safety-group records · 0 quality-of-life measures

      →

      NCT00492089 · Registry condition search · Scope: unclear

      Bevacizumab in Reducing CNS Side Effects in Patients Who Have Undergone Radiation Therapy to the Brain for Primary Brain Tumor, Meningioma, or Head and Neck Cancer

      1 outcome links · 2 safety-group records · 0 quality-of-life measures

      →

      NCT00513435 · Registry condition search · Scope: unclear

      Saracatinib in Treating Patients With Recurrent or Metastatic Head and Neck Cancer

      2 outcome links · 1 safety-group records · 0 quality-of-life measures

      →

      NCT00895245 · Registry condition search · Scope: unclear

      Fosaprepitant Dimeglumine, Palonosetron Hydrochloride, and Dexamethasone in Preventing Nausea and Vomiting Caused by Cisplatin in Patients With Stage III or Stage IV Head and Neck

      4 outcome links · 1 safety-group records · 1 quality-of-life measures

      →

      NCT01192815 · Registry condition search · Scope: unclear

      Erlotinib Hydrochloride and Radiation Therapy in Stage III-IV Squamous Cell Cancer of the Head and Neck

      6 outcome links · 1 safety-group records · 1 quality-of-life measures

      →

      NCT01326923 · Registry condition search · Scope: unclear

      Induction Chemo Then Concurrent Chemoradiotherapy With Cetuximab in Locally Advanced Head and Neck Squamous Cell Cancer

      2 outcome links · 1 safety-group records · 0 quality-of-life measures

      →

      NCT01611662 · Registry condition search · Scope: unclear

      Gemcitabine Hydrochloride and Cisplatin Before Surgery in Treating Patients With Muscle Invasive Bladder Cancer

      1 outcome links · 1 safety-group records · 0 quality-of-life measures

      →

      NCT01682031 · Registry condition search · Scope: unclear

      Selenomethionine in Reducing Mucositis in Patients With Locally Advanced Head and Neck Cancer Who Are Receiving Cisplatin and Radiation Therapy

      6 outcome links · 2 safety-group records · 1 quality-of-life measures

      →

      NCT02001623 · Source cited / selected · Scope: unclear

      Tisotumab Vedotin (HuMax®-TF-ADC) Safety Study in Patients With Solid Tumors

      6 outcome links · 15 safety-group records · 0 quality-of-life measures

      →

      NCT02007200 · Registry condition search · Scope: unclear

      Soy Isoflavones in Preventing Head and Neck Cancer Recurrence in Patients With Stage I-IV Head and Neck Cancer Undergoing Surgery

      4 outcome links · 1 safety-group records · 0 quality-of-life measures

      →

      NCT02113878 · Registry condition search · Scope: unclear

      Phase Ib Study of BKM120 With Cisplatin and XRT in High Risk Locally Advanced Squamous Cell Cancer of Head and Neck

      6 outcome links · 2 safety-group records · 0 quality-of-life measures

      →

      NCT02123511 · Registry condition search · Scope: unclear

      Acetylcysteine Rinse in Reducing Saliva Thickness and Mucositis in Patients With Head and Neck Cancer Undergoing Radiation Therapy

      6 outcome links · 2 safety-group records · 3 quality-of-life measures

      →

      NCT02177838 · Registry condition search · Scope: unclear

      Cetuximab and Radiation Therapy in Treating Patients With Stage III-IV Head and Neck Cancer

      3 outcome links · 1 safety-group records · 0 quality-of-life measures

      →

      NCT02186847 · Source cited / selected · Scope: unclear

      Chemotherapy and Radiation Therapy With or Without Metformin Hydrochloride in Treating Patients With Stage III Non-small Cell Lung Cancer

      5 outcome links · 2 safety-group records · 0 quality-of-life measures

      →

      NCT02388932 · Registry condition search · Scope: unclear

      Stereotactic Body Radiation Therapy in Treating Patients With High Risk Locally Advanced Head and Neck Cancer

      6 outcome links · 1 safety-group records · 1 quality-of-life measures

      →

      NCT02452424 · Registry condition search · Scope: unclear

      A Combination Clinical Study of PLX3397 and Pembrolizumab To Treat Advanced Melanoma and Other Solid Tumors

      2 outcome links · 11 safety-group records · 0 quality-of-life measures

      →

      NCT02466971 · Registry condition search · Scope: unclear

      Testing the Addition of a New Anti-Cancer Drug, Triapine, to the Usual Chemotherapy Treatment (Cisplatin) During Radiation Therapy for Advanced-stage Cervical and Vaginal Cancers

      6 outcome links · 2 safety-group records · 0 quality-of-life measures

      →

      NCT02538510 · Registry condition search · Scope: unclear

      Pembrolizumab and Vorinostat in Treating Patients With Recurrent Squamous Cell Head and Neck Cancer or Salivary Gland Cancer That Is Metastatic and/or Cannot Be Removed by Surgery

      4 outcome links · 2 safety-group records · 0 quality-of-life measures

      →
      Source relationships and population-mapping limitations
      bindings
        mappings

          Download this complete draft source relationship record →

          Preserved source evidence · Not medical advice