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DISEASE & TREATMENT SETTING

Zirabev: metastatic Renal cell carcinoma

Source-derived catalogue. This is not a treatment recommendation or a personalised trial match.

Exact scope

1.4 Metastatic Renal Cell Carcinoma ZIRABEV, in combination with interferon alfa, is indicated for the treatment of metastatic renal cell carcinoma (mRCC).

Broader topic: Renal Cell Cancer

Source population
Not part of this definition
Disease extent
metastatic
Treatment line
Not part of this definition
Stage
Not part of this definition
Resectability
Not part of this definition
Biomarkers, prior therapy and derivation
molecular
    prior therapy
      derivation status
      source-attested
      derivation note
      Scoped from the FDA approved indication for Zirabev (product label). Only dimensions stated in that wording are part of this definition.
      source wording
      1.4 Metastatic Renal Cell Carcinoma ZIRABEV, in combination with interferon alfa, is indicated for the treatment of metastatic renal cell carcinoma (mRCC).

      Study evidence for this setting

      27 linked studies · Applicability is a draft source assessment, not a determination of your eligibility.

      NCT00073307 · Source cited / selected · Scope: unclear

      Study of BAY43-9006 in Patients With Unresectable and/or Metastatic Renal Cell Cancer

      6 outcome links · 4 safety-group records · 2 quality-of-life measures

      →

      NCT00334282 · Source cited / selected · Scope: unclear

      Safety and Efficacy of GW786034 (Pazopanib) In Metastatic Renal Cell Carcinoma

      6 outcome links · 2 safety-group records · 4 quality-of-life measures

      →

      NCT00387764 · Source cited / selected · Scope: unclear

      Extension Study to VEG105192 to Assess Pazopanib in Patients With Advanced/Metastatic Renal Cell Cancer

      6 outcome links · 1 safety-group records · 0 quality-of-life measures

      →

      NCT00410124 · Source cited / selected · Scope: unclear

      RAD001 Plus Best Supportive Care (BSC) Versus BSC Plus Placebo in Patients With Metastatic Carcinoma of the Kidney Which Has Progressed After Treatment With Sorafenib and/or Suniti

      6 outcome links · 3 safety-group records · 3 quality-of-life measures

      →

      NCT00720941 · Source cited / selected · Scope: unclear

      Pazopanib Versus Sunitinib in the Treatment of Locally Advanced and/or Metastatic Renal Cell Carcinoma

      6 outcome links · 4 safety-group records · 8 quality-of-life measures

      →

      NCT00738530 · Source cited / selected · Scope: unclear

      A Study of Avastin (Bevacizumab) Added to Interferon Alfa-2a (Roferon) Therapy in Patients With Metastatic Renal Cell Cancer With Nephrectomy

      6 outcome links · 2 safety-group records · 0 quality-of-life measures

      →

      NCT01064310 · Source cited / selected · Scope: unclear

      Patient Preference Study of Pazopanib Versus Sunitinib in Advanced or Metastatic Kidney Cancer

      6 outcome links · 3 safety-group records · 3 quality-of-life measures

      →

      NCT01136733 · Source cited / selected · Scope: unclear

      A Study of E7080 Alone, and in Combination With Everolimus in Subjects With Unresectable Advanced or Metastatic Renal Cell Carcinoma Following One Prior Vascular Endothelial Growth

      6 outcome links · 7 safety-group records · 0 quality-of-life measures

      →

      NCT01631552 · Source cited / selected · Scope: unclear

      Study of Sacituzumab Govitecan-hziy (IMMU-132) in Adults With Epithelial Cancer

      6 outcome links · 1 safety-group records · 0 quality-of-life measures

      →

      NCT01806675 · Registry condition search · Scope: unclear

      18F-FPPRGD2 PET/CT or PET/MRI in Predicting Early Response in Patients With Cancer Receiving Anti-Angiogenesis Therapy

      5 outcome links · 3 safety-group records · 1 quality-of-life measures

      →

      NCT01835158 · Source cited / selected · Scope: unclear

      Cabozantinib-s-malate or Sunitinib Malate in Treating Patients With Previously Untreated Locally Advanced or Metastatic Kidney Cancer

      3 outcome links · 2 safety-group records · 0 quality-of-life measures

      →

      NCT01865747 · Source cited / selected · Scope: unclear

      A Study of Cabozantinib (XL184) vs Everolimus in Subjects With Metastatic Renal Cell Carcinoma

      3 outcome links · 2 safety-group records · 0 quality-of-life measures

      →

      NCT02231749 · Source cited / selected · Scope: unclear

      Nivolumab Combined With Ipilimumab Versus Sunitinib in Previously Untreated Advanced or Metastatic Renal Cell Carcinoma (CheckMate 214)

      6 outcome links · 3 safety-group records · 0 quality-of-life measures

      →

      NCT02599194 · Registry condition search · Scope: unclear

      18F-FSPG PET/CT for Cancer Patients on Therapy

      3 outcome links · 1 safety-group records · 0 quality-of-life measures

      →

      NCT02721732 · Registry condition search · Scope: unclear

      Pembrolizumab in Treating Patients With Rare Tumors That Cannot Be Removed by Surgery or Are Metastatic

      6 outcome links · 1 safety-group records · 0 quality-of-life measures

      →

      NCT02853331 · Source cited / selected · Scope: unclear

      Study to Evaluate the Efficacy and Safety of Pembrolizumab (MK-3475) in Combination With Axitinib Versus Sunitinib Monotherapy in Participants With Renal Cell Carcinoma (MK-3475-42

      6 outcome links · 2 safety-group records · 4 quality-of-life measures

      →

      NCT02983045 · Registry condition search · Scope: unclear

      A Dose Escalation and Cohort Expansion Study of NKTR-214 in Combination With Nivolumab and Other Anti-Cancer Therapies in Patients With Select Advanced Solid Tumors

      3 outcome links · 10 safety-group records · 0 quality-of-life measures

      →

      NCT03141177 · Source cited / selected · Scope: unclear

      A Study of Nivolumab Combined With Cabozantinib Compared to Sunitinib in Previously Untreated Advanced or Metastatic Renal Cell Carcinoma

      6 outcome links · 3 safety-group records · 0 quality-of-life measures

      →

      NCT03154190 · Registry condition search · Scope: unclear

      Health Care Coach Support in Reducing Acute Care Use and Cost in Patients With Cancer

      6 outcome links · 2 safety-group records · 0 quality-of-life measures

      →

      NCT03595124 · Source cited / selected · Scope: unclear

      A Study to Compare Treatments for a Type of Kidney Cancer Called TFE/Translocation Renal Cell Carcinoma (tRCC)

      6 outcome links · 3 safety-group records · 0 quality-of-life measures

      →
      Source relationships and population-mapping limitations
      bindings
        mappings

          Download this complete draft source relationship record →

          Preserved source evidence · Not medical advice