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DISEASE & TREATMENT SETTING

Primary Central Nervous System Lymphoma

Source-derived catalogue. This is not a treatment recommendation or a personalised trial match.

Exact scope

Primary Central Nervous System Lymphoma

Source population
Not part of this definition
Disease extent
Not part of this definition
Treatment line
Not part of this definition
Stage
Not part of this definition
Resectability
Not part of this definition
Biomarkers, prior therapy and derivation
molecular
    prior therapy
      derivation status
      source-attested
      derivation note
      Derived from NCI topic(s): Primary Central Nervous System Lymphoma. Strongest NCIt resolution: exact. Entity-level scope; stage, biomarker and treatment line are not yet part of this definition.
      source wording
      Source null
      1 more-specific settings

      Study evidence for this setting

      12 linked studies · Applicability is a draft source assessment, not a determination of your eligibility.

      NCT00103038 · Registry condition search · Scope: narrower

      Ferumoxytol in Improving MR Imaging in Patients With High-Grade Brain Tumors or Cerebral Metastases

      5 outcome links · 1 safety-group records · 0 quality-of-life measures

      →

      NCT00112593 · Registry condition search · Scope: narrower

      Fludarabine and Total-Body Irradiation Followed By Donor Stem Cell Transplant and Cyclosporine and Mycophenolate Mofetil in Treating HIV-Positive Patients With or Without Cancer

      6 outcome links · 1 safety-group records · 0 quality-of-life measures

      →

      NCT00918333 · Registry condition search · Scope: narrower

      Panobinostat and Everolimus in Treating Patients With Recurrent Multiple Myeloma, Non-Hodgkin Lymphoma, or Hodgkin Lymphoma

      6 outcome links · 2 safety-group records · 0 quality-of-life measures

      →

      NCT01011920 · Registry condition search · Scope: narrower

      Trial for Patients With Newly Diagnosed Primary Central Nervous System (CNS) Lymphoma

      4 outcome links · 5 safety-group records · 0 quality-of-life measures

      →

      NCT01789255 · Registry condition search · Scope: narrower

      Vorinostat, Tacrolimus, and Methotrexate in Preventing GVHD After Stem Cell Transplant in Patients With Hematological Malignancies

      6 outcome links · 1 safety-group records · 0 quality-of-life measures

      →

      NCT01973062 · Registry condition search · Scope: narrower

      Yttrium Y 90 Ibritumomab Tiuxetan and Rituximab in Primary Central Nervous System Non-Hodgkin Lymphoma

      5 outcome links · 1 safety-group records · 0 quality-of-life measures

      →

      NCT02113007 · Registry condition search · Scope: narrower

      Study of High-Dose Rituximab With Temozolomide as Treatment for Primary Central Nervous System (CNS) Lymphoma

      3 outcome links · 1 safety-group records · 0 quality-of-life measures

      →

      NCT02301364 · Registry condition search · Scope: narrower

      Buparlisib (BKM120) In Patients With Recurrent/Refractory Primary Central Nervous System Lymphoma (PCNSL) and Recurrent/Refractory Secondary Central Nervous System Lymphoma (SCNSL)

      4 outcome links · 1 safety-group records · 0 quality-of-life measures

      →

      NCT02420795 · Registry condition search · Scope: narrower

      Akt/ERK Inhibitor ONC201 in Treating Patients With Relapsed or Refractory Non-Hodgkin's Lymphoma

      4 outcome links · 3 safety-group records · 0 quality-of-life measures

      →

      NCT03038672 · Registry condition search · Scope: narrower

      Nivolumab With or Without Varlilumab in Treating Patients With Relapsed or Refractory Aggressive B-cell Lymphomas

      6 outcome links · 3 safety-group records · 0 quality-of-life measures

      →

      NCT03255018 · Registry condition search · Scope: narrower

      Pembrolizumab in Relapsed and Refractory Gray-Zone Lymphoma (GZL), Primary Central Nervous System Lymphoma (PCNSL), and Other Extranodal Diffuse Large B-cell Lymphomas

      6 outcome links · 2 safety-group records · 0 quality-of-life measures

      →

      NCT04548648 · Registry condition search · Scope: narrower

      A Pilot Study of Acalabrutinib in Relapsed/Refractory Primary and Secondary CNS Lymphomas

      6 outcome links · 1 safety-group records · 0 quality-of-life measures

      →
      Source relationships and population-mapping limitations
      bindings
      1. release id
        clinical-indications-draft-1
        disease state id
        ds-primary-central-nervous-system-lymphoma
        binding id
        ncit-C9301
        source collection
        ncit-concept
        source key
        C9301
        source excerpt
        Source null
        match status
        exact
        match note
        Source null
        recorded at
        2026-09-10T00:00:00Z
      mappings

        Download this complete draft source relationship record →

        Preserved source evidence · Not medical advice