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DISEASE & TREATMENT SETTING

locally advanced Oropharyngeal Cancer

Source-derived catalogue. This is not a treatment recommendation or a personalised trial match.

Exact scope

Surgery Followed by Postoperative Radiation Therapy (PORT) With or Without Concurrent Chemotherapy for Patients With Locally Advanced Disease

Broader topic: Oropharyngeal Cancer

Source population
Not part of this definition
Disease extent
locally-advanced
Treatment line
Not part of this definition
Stage
Not part of this definition
Resectability
Not part of this definition
Biomarkers, prior therapy and derivation
molecular
    prior therapy
      derivation status
      source-attested
      derivation note
      Scoped from an NCI treatment-summary heading. NCI PDQ is an evidence summary, not a practice guideline, and only the dimensions the heading states are part of this definition.
      source wording
      Surgery Followed by Postoperative Radiation Therapy (PORT) With or Without Concurrent Chemotherapy for Patients With Locally Advanced Disease

      Study evidence for this setting

      24 linked studies · Applicability is a draft source assessment, not a determination of your eligibility.

      NCT00410826 · Registry condition search · Scope: unclear

      Cisplatin and Radiation Therapy With or Without Erlotinib Hydrochloride in Treating Patients With Stage III or Stage IV Head and Neck Cancer

      3 outcome links · 2 safety-group records · 0 quality-of-life measures

      →

      NCT00492089 · Registry condition search · Scope: unclear

      Bevacizumab in Reducing CNS Side Effects in Patients Who Have Undergone Radiation Therapy to the Brain for Primary Brain Tumor, Meningioma, or Head and Neck Cancer

      1 outcome links · 2 safety-group records · 0 quality-of-life measures

      →

      NCT00513435 · Registry condition search · Scope: unclear

      Saracatinib in Treating Patients With Recurrent or Metastatic Head and Neck Cancer

      2 outcome links · 1 safety-group records · 0 quality-of-life measures

      →

      NCT00895245 · Registry condition search · Scope: unclear

      Fosaprepitant Dimeglumine, Palonosetron Hydrochloride, and Dexamethasone in Preventing Nausea and Vomiting Caused by Cisplatin in Patients With Stage III or Stage IV Head and Neck

      4 outcome links · 1 safety-group records · 1 quality-of-life measures

      →

      NCT01192815 · Registry condition search · Scope: unclear

      Erlotinib Hydrochloride and Radiation Therapy in Stage III-IV Squamous Cell Cancer of the Head and Neck

      6 outcome links · 1 safety-group records · 1 quality-of-life measures

      →

      NCT01682031 · Registry condition search · Scope: unclear

      Selenomethionine in Reducing Mucositis in Patients With Locally Advanced Head and Neck Cancer Who Are Receiving Cisplatin and Radiation Therapy

      6 outcome links · 2 safety-group records · 1 quality-of-life measures

      →

      NCT01898494 · Source cited / selected · Scope: unclear

      Transoral Surgery Followed By Low-Dose or Standard-Dose Radiation Therapy With or Without Chemotherapy in Treating Patients With HPV Positive Stage III-IVA Oropharyngeal Cancer

      6 outcome links · 5 safety-group records · 3 quality-of-life measures

      →

      NCT02007200 · Registry condition search · Scope: unclear

      Soy Isoflavones in Preventing Head and Neck Cancer Recurrence in Patients With Stage I-IV Head and Neck Cancer Undergoing Surgery

      4 outcome links · 1 safety-group records · 0 quality-of-life measures

      →

      NCT02113878 · Registry condition search · Scope: unclear

      Phase Ib Study of BKM120 With Cisplatin and XRT in High Risk Locally Advanced Squamous Cell Cancer of Head and Neck

      6 outcome links · 2 safety-group records · 0 quality-of-life measures

      →

      NCT02123511 · Registry condition search · Scope: unclear

      Acetylcysteine Rinse in Reducing Saliva Thickness and Mucositis in Patients With Head and Neck Cancer Undergoing Radiation Therapy

      6 outcome links · 2 safety-group records · 3 quality-of-life measures

      →

      NCT02177838 · Registry condition search · Scope: unclear

      Cetuximab and Radiation Therapy in Treating Patients With Stage III-IV Head and Neck Cancer

      3 outcome links · 1 safety-group records · 0 quality-of-life measures

      →

      NCT02254278 · Source cited / selected · Scope: unclear

      Reduced-Dose Intensity-Modulated Radiation Therapy With or Without Cisplatin in Treating Patients With Advanced Oropharyngeal Cancer

      6 outcome links · 2 safety-group records · 1 quality-of-life measures

      →

      NCT02388932 · Registry condition search · Scope: unclear

      Stereotactic Body Radiation Therapy in Treating Patients With High Risk Locally Advanced Head and Neck Cancer

      6 outcome links · 1 safety-group records · 1 quality-of-life measures

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      NCT02567422 · Registry condition search · Scope: unclear

      Testing the Addition of M6620 (VX-970, Berzosertib) to Usual Chemotherapy and Radiation for Head and Neck Cancer

      6 outcome links · 4 safety-group records · 0 quality-of-life measures

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      NCT02586207 · Registry condition search · Scope: unclear

      Pembrolizumab in Combination With CRT for LA-SCCHN

      2 outcome links · 1 safety-group records · 0 quality-of-life measures

      →

      NCT03032250 · Registry condition search · Scope: unclear

      Prepare to Care, A Supported Self-Management Intervention for Head and Neck Cancer CaregiversHead and Neck Cancer

      6 outcome links · 2 safety-group records · 1 quality-of-life measures

      →

      NCT03174275 · Registry condition search · Scope: unclear

      Carboplatin, Nab-Paclitaxel, Durvalumab Before Surgery and Adjuvant Therapy in Head and Neck Squamous Cell Carcinoma

      6 outcome links · 1 safety-group records · 0 quality-of-life measures

      →

      NCT03258554 · Registry condition search · Scope: unclear

      Radiation Therapy With Durvalumab or Cetuximab in Treating Patients With Locoregionally Advanced Head and Neck Cancer Who Cannot Take Cisplatin

      6 outcome links · 3 safety-group records · 12 quality-of-life measures

      →

      NCT03342911 · Registry condition search · Scope: unclear

      Nivolumab, Carboplatin, and Paclitaxel in Treating Patients With Stage III-IV Head and Neck Squamous Cell Carcinoma That Can Be Removed by Surgery

      2 outcome links · 1 safety-group records · 0 quality-of-life measures

      →

      NCT04162873 · Registry condition search · Scope: unclear

      Celecoxib Through Surgery and Radiation Therapy for the Treatment of Advanced Head and Neck Cancer

      6 outcome links · 2 safety-group records · 2 quality-of-life measures

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      Source relationships and population-mapping limitations
      bindings
        mappings

          Download this complete draft source relationship record →

          Preserved source evidence · Not medical advice