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DISEASE & TREATMENT SETTING

Zydelig: recurrent non-Hodgkin lymphoma after prior therapy

Source-derived catalogue. This is not a treatment recommendation or a personalised trial match.

Exact scope

For the treatment of relapsed follicular B-cell Non-Hodgkin Lymphoma (FL) in patients who have received at least 2 prior systemic therapies and relapsed small lymphocytic lymphoma (SLL) in patients who have received at least 2 prior systemic therapies

Broader topic: Non-Hodgkin Lymphoma

Source population
Not part of this definition
Disease extent
recurrent
Treatment line
Not part of this definition
Stage
Not part of this definition
Resectability
Not part of this definition
Biomarkers, prior therapy and derivation
molecular
    prior therapy
    1. class
      who have received at least 2 prior systemic therapies and relapsed small lymphocytic lymphoma (SLL) in pati
      status
      required
    derivation status
    source-attested
    derivation note
    Scoped from the FDA approved indication for Zydelig (idelalisib) (accelerated-approval table). Only dimensions stated in that wording are part of this definition.
    source wording
    For the treatment of relapsed follicular B-cell Non-Hodgkin Lymphoma (FL) in patients who have received at least 2 prior systemic therapies and relapsed small lymphocytic lymphoma (SLL) in patients who have received at least 2 prior systemic therapies

    Study evidence for this setting

    167 linked studies · Applicability is a draft source assessment, not a determination of your eligibility.

    NCT00007345 · Source cited / selected · Scope: unclear

    Depsipeptide to Treat Patients With Cutaneous T-Cell Lymphoma and Peripheral T-Cell Lymphoma

    6 outcome links · 2 safety-group records · 0 quality-of-life measures

    →

    NCT00012298 · Registry condition search · Scope: unclear

    Radiolabeled Monoclonal Antibody Plus Rituximab With and Without Filgrastim and Interleukin-11 in Treating Patients With Relapsed or Refractory Non-Hodgkin's Lymphoma

    6 outcome links · 7 safety-group records · 2 quality-of-life measures

    →

    NCT00040846 · Registry condition search · Scope: unclear

    Alemtuzumab, Fludarabine Phosphate, and Low-Dose Total Body Irradiation Before Donor Stem Cell Transplantation in Treating Patients With Hematological Malignancies

    5 outcome links · 6 safety-group records · 0 quality-of-life measures

    →

    NCT00049504 · Registry condition search · Scope: unclear

    Haploidentical Donor Bone Marrow Transplant in Treating Patients With High-Risk Hematologic Cancer

    3 outcome links · 1 safety-group records · 0 quality-of-life measures

    →

    NCT00054639 · Registry condition search · Scope: unclear

    Oblimersen Sodium and Rituximab in Treating Patients With Recurrent B-cell Non-Hodgkin Lymphoma

    1 outcome links · 1 safety-group records · 0 quality-of-life measures

    →

    NCT00058240 · Registry condition search · Scope: unclear

    Flavopiridol in Treating Patients With Previously Treated Chronic Lymphocytic Leukemia or Lymphocytic Lymphoma

    3 outcome links · 2 safety-group records · 0 quality-of-life measures

    →

    NCT00068718 · Registry condition search · Scope: unclear

    Donor Lymphocyte Infusion in Treating Patients With Persistent, Relapsed, or Progressing Cancer After Donor Hematopoietic Cell Transplant

    6 outcome links · 1 safety-group records · 0 quality-of-life measures

    →

    NCT00072514 · Registry condition search · Scope: unclear

    Gemcitabine Hydrochloride, Carboplatin, Dexamethasone, and Rituximab in Treating Patients With Previously Treated Lymphoid Malignancies

    4 outcome links · 1 safety-group records · 0 quality-of-life measures

    →

    NCT00073918 · Registry condition search · Scope: unclear

    Iodine I 131 Tositumomab, Etoposide and Cyclophosphamide Followed by Autologous Stem Cell Transplant in Treating Patients With Relapsed or Refractory Non-Hodgkin's Lymphoma

    4 outcome links · 1 safety-group records · 0 quality-of-life measures

    →

    NCT00089011 · Registry condition search · Scope: unclear

    Tacrolimus and Mycophenolate Mofetil in Preventing Graft-Versus-Host Disease in Patients Who Have Undergone Total-Body Irradiation With or Without Fludarabine Phosphate Followed by

    6 outcome links · 2 safety-group records · 0 quality-of-life measures

    →

    NCT00089076 · Registry condition search · Scope: unclear

    MDX-010 in Treating Patients With Recurrent or Refractory Lymphoma

    6 outcome links · 1 safety-group records · 0 quality-of-life measures

    →

    NCT00105001 · Registry condition search · Scope: unclear

    Tacrolimus and Mycophenolate Mofetil With or Without Sirolimus in Preventing Acute Graft-Versus-Host Disease in Patients Who Are Undergoing Donor Stem Cell Transplant for Hematolog

    5 outcome links · 3 safety-group records · 0 quality-of-life measures

    →

    NCT00112723 · Registry condition search · Scope: unclear

    Flavopiridol in Treating Patients With Relapsed or Refractory Lymphoma or Multiple Myeloma

    6 outcome links · 1 safety-group records · 0 quality-of-life measures

    →

    NCT00118352 · Registry condition search · Scope: unclear

    Alemtuzumab, Fludarabine Phosphate, and Total-Body Irradiation Followed by Cyclosporine and Mycophenolate Mofetil in Treating Patients Who Are Undergoing Donor Stem Cell Transplant

    6 outcome links · 3 safety-group records · 0 quality-of-life measures

    →

    NCT00119392 · Registry condition search · Scope: unclear

    Yttrium Y 90 Ibritumomab Tiuxetan, Fludarabine, Radiation Therapy, and Donor Stem Cell Transplant in Treating Patients With Relapsed or Refractory Non-Hodgkin's Lymphoma

    5 outcome links · 1 safety-group records · 0 quality-of-life measures

    →

    NCT00131937 · Registry condition search · Scope: unclear

    Sorafenib Tosylate in Treating Patients With Recurrent Aggressive Non-Hodgkin's Lymphoma

    3 outcome links · 1 safety-group records · 0 quality-of-life measures

    →

    NCT00244855 · Registry condition search · Scope: unclear

    Rituximab and Dexamethasone in Treating Patients With Low-Grade Non-Hodgkin Lymphoma

    2 outcome links · 2 safety-group records · 0 quality-of-life measures

    →

    NCT00274651 · Registry condition search · Scope: unclear

    A Phase II Clinical Trial of PXD101 in Patients With Recurrent or Refractory Cutaneous and Peripheral T-Cell Lymphomas

    6 outcome links · 2 safety-group records · 2 quality-of-life measures

    →

    NCT00288067 · Registry condition search · Scope: unclear

    Fenretinide and Rituximab in Treating Patients With B-Cell Non-Hodgkin Lymphoma

    2 outcome links · 1 safety-group records · 0 quality-of-life measures

    →

    NCT00290472 · Registry condition search · Scope: unclear

    CCI-779 in Treating Patients With Recurrent or Refractory B-Cell Non-Hodgkin's Lymphoma or Chronic Lymphocytic Leukemia

    3 outcome links · 1 safety-group records · 0 quality-of-life measures

    →
    Source relationships and population-mapping limitations
    bindings
      mappings

        Download this complete draft source relationship record →

        Preserved source evidence · Not medical advice