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DISEASE & TREATMENT SETTING

Lynparza: advanced peritoneal cancer with BRCA stated without a specific alteration (first-line)

Source-derived catalogue. This is not a treatment recommendation or a personalised trial match.

Exact scope

• for the maintenance treatment of adult patients with deleterious or suspected deleterious germline or somatic BRCA -mutated advanced epithelial ovarian, fallopian tube or primary peritoneal cancer who are in complete or partial response to first-line platinum-based chemotherapy.

Broader topic: Malignant Peritoneal Neoplasm

Source population
Not part of this definition
Disease extent
advanced
Treatment line
first-line
Stage
Not part of this definition
Resectability
Not part of this definition
Biomarkers, prior therapy and derivation
molecular
  1. gene
    BRCA
    alteration
    stated without a specific alteration
    status
    present
prior therapy
    derivation status
    source-attested
    derivation note
    Scoped from the FDA approved indication for Lynparza (product label). Only dimensions stated in that wording are part of this definition.
    source wording
    • for the maintenance treatment of adult patients with deleterious or suspected deleterious germline or somatic BRCA -mutated advanced epithelial ovarian, fallopian tube or primary peritoneal cancer who are in complete or partial response to first-line platinum-based chemotherapy.

    Study evidence for this setting

    1 linked studies · Applicability is a draft source assessment, not a determination of your eligibility.

    Source relationships and population-mapping limitations
    bindings
      mappings

        Download this complete draft source relationship record →

        Preserved source evidence · Not medical advice