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DISEASE & TREATMENT SETTING

Opdivo: recurrent Hodgkin Lymphoma

Source-derived catalogue. This is not a treatment recommendation or a personalised trial match.

Exact scope

Treatment of adult patients with classical Hodgkin lymphoma that has relapsed or progressed after:Autologous hematopoietic stem cell transplantation (HSCT) and brentuximab vedotin, Or3 or more lines of systemic therapy that includes autologous HSCT

Broader topic: Hodgkin Lymphoma

Source population
Not part of this definition
Disease extent
recurrent
Treatment line
Not part of this definition
Stage
Not part of this definition
Resectability
Not part of this definition
Biomarkers, prior therapy and derivation
molecular
    prior therapy
      derivation status
      source-attested
      derivation note
      Scoped from the FDA approved indication for Opdivo (nivolumab) (accelerated-approval table). Only dimensions stated in that wording are part of this definition.
      source wording
      Treatment of adult patients with classical Hodgkin lymphoma that has relapsed or progressed after:Autologous hematopoietic stem cell transplantation (HSCT) and brentuximab vedotin, Or3 or more lines of systemic therapy that includes autologous HSCT

      Study evidence for this setting

      64 linked studies · Applicability is a draft source assessment, not a determination of your eligibility.

      NCT00040846 · Registry condition search · Scope: unclear

      Alemtuzumab, Fludarabine Phosphate, and Low-Dose Total Body Irradiation Before Donor Stem Cell Transplantation in Treating Patients With Hematological Malignancies

      5 outcome links · 6 safety-group records · 0 quality-of-life measures

      →

      NCT00049504 · Registry condition search · Scope: unclear

      Haploidentical Donor Bone Marrow Transplant in Treating Patients With High-Risk Hematologic Cancer

      3 outcome links · 1 safety-group records · 0 quality-of-life measures

      →

      NCT00068718 · Registry condition search · Scope: unclear

      Donor Lymphocyte Infusion in Treating Patients With Persistent, Relapsed, or Progressing Cancer After Donor Hematopoietic Cell Transplant

      6 outcome links · 1 safety-group records · 0 quality-of-life measures

      →

      NCT00072514 · Registry condition search · Scope: unclear

      Gemcitabine Hydrochloride, Carboplatin, Dexamethasone, and Rituximab in Treating Patients With Previously Treated Lymphoid Malignancies

      4 outcome links · 1 safety-group records · 0 quality-of-life measures

      →

      NCT00089011 · Registry condition search · Scope: unclear

      Tacrolimus and Mycophenolate Mofetil in Preventing Graft-Versus-Host Disease in Patients Who Have Undergone Total-Body Irradiation With or Without Fludarabine Phosphate Followed by

      6 outcome links · 2 safety-group records · 0 quality-of-life measures

      →

      NCT00089076 · Registry condition search · Scope: unclear

      MDX-010 in Treating Patients With Recurrent or Refractory Lymphoma

      6 outcome links · 1 safety-group records · 0 quality-of-life measures

      →

      NCT00105001 · Registry condition search · Scope: unclear

      Tacrolimus and Mycophenolate Mofetil With or Without Sirolimus in Preventing Acute Graft-Versus-Host Disease in Patients Who Are Undergoing Donor Stem Cell Transplant for Hematolog

      5 outcome links · 3 safety-group records · 0 quality-of-life measures

      →

      NCT00112723 · Registry condition search · Scope: unclear

      Flavopiridol in Treating Patients With Relapsed or Refractory Lymphoma or Multiple Myeloma

      6 outcome links · 1 safety-group records · 0 quality-of-life measures

      →

      NCT00118352 · Registry condition search · Scope: unclear

      Alemtuzumab, Fludarabine Phosphate, and Total-Body Irradiation Followed by Cyclosporine and Mycophenolate Mofetil in Treating Patients Who Are Undergoing Donor Stem Cell Transplant

      6 outcome links · 3 safety-group records · 0 quality-of-life measures

      →

      NCT00288067 · Registry condition search · Scope: unclear

      Fenretinide and Rituximab in Treating Patients With B-Cell Non-Hodgkin Lymphoma

      2 outcome links · 1 safety-group records · 0 quality-of-life measures

      →

      NCT00408681 · Registry condition search · Scope: unclear

      Lithium Carbonate in Treating Patients With Acute Intestinal Graft-Versus-Host-Disease (GVHD) After Donor Stem Cell Transplant

      6 outcome links · 1 safety-group records · 0 quality-of-life measures

      →

      NCT00481871 · Registry condition search · Scope: unclear

      Study of Pralatrexate & Gemcitabine With B12 & Folic Acid to Treat Relapsed/Refractory Lymphoproliferative Malignancies

      3 outcome links · 3 safety-group records · 0 quality-of-life measures

      →

      NCT00536601 · Registry condition search · Scope: unclear

      High-Dose Chemotherapy With or Without Total-Body Irradiation Followed by Autologous Stem Cell Transplant in Treating Patients With Hematologic Cancer or Solid Tumors

      4 outcome links · 5 safety-group records · 0 quality-of-life measures

      →

      NCT00601718 · Registry condition search · Scope: unclear

      Vorinostat, Rituximab, Ifosfamide, Carboplatin, and Etoposide in Treating Patients With Relapsed or Refractory Lymphoma or Previously Untreated T-Cell Non-Hodgkin Lymphoma or Mantl

      4 outcome links · 1 safety-group records · 0 quality-of-life measures

      →

      NCT00723099 · Registry condition search · Scope: unclear

      Donor Umbilical Cord Blood Transplant in Treating Patients With Hematologic Cancer

      6 outcome links · 1 safety-group records · 0 quality-of-life measures

      →

      NCT00789776 · Registry condition search · Scope: unclear

      Fludarabine Phosphate, Cyclophosphamide, Total-Body Irradiation, and Donor Bone Marrow Transplant Followed by Donor Natural Killer Cell Therapy, Mycophenolate Mofetil, and Tacrolim

      6 outcome links · 2 safety-group records · 1 quality-of-life measures

      →

      NCT00795769 · Registry condition search · Scope: unclear

      Ondansetron in Preventing Nausea and Vomiting in Patients Undergoing Stem Cell Transplant

      1 outcome links · 1 safety-group records · 0 quality-of-life measures

      →

      NCT00848926 · Source cited / selected · Scope: unclear

      A Pivotal Open-Label Trial of Brentuximab Vedotin for Hodgkin Lymphoma

      6 outcome links · 1 safety-group records · 0 quality-of-life measures

      →

      NCT00856388 · Registry condition search · Scope: unclear

      Fludarabine Phosphate, Melphalan, Total-Body Irradiation, Donor Stem Cell Transplant in Treating Patients With Hematologic Cancer or Bone Marrow Failure Disorders

      6 outcome links · 1 safety-group records · 0 quality-of-life measures

      →

      NCT00867529 · Registry condition search · Scope: unclear

      Rituximab in Treating Patients Undergoing Donor Peripheral Blood Stem Cell Transplant for Relapsed or Refractory B-cell Lymphoma

      5 outcome links · 1 safety-group records · 0 quality-of-life measures

      →
      Source relationships and population-mapping limitations
      bindings
        mappings

          Download this complete draft source relationship record →

          Preserved source evidence · Not medical advice