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DISEASE & TREATMENT SETTING

CARMUSTINE: metastatic Hodgkin's Lymphoma

Source-derived catalogue. This is not a treatment recommendation or a personalised trial match.

Exact scope

1 INDICATIONS AND USAGE Carmustine for Injection, USP is a nitrosourea indicated as palliative therapy as a single agent or in established combination therapy with other approved chemotherapeutic agents in the following: Brain tumors glioblastoma, brainstem glioma, medulloblastoma, astrocytoma, ependymoma, and metastatic brain tumors ( 1 ) Multiple myeloma-in combination with prednisone ( 1 ) Relapsed or refractory Hodgkin's lymphoma in combination with other approved drugs ( 1 ) Relapsed or refractory Non-Hodgkin's lymphomas in combination with other approved drugs ( 1 ) Carmustine for Injection, USP is indicated as palliative therapy as a single agent or in established combination therapy in the following: Brain tumors glioblastoma, brainstem glioma, medulloblastoma, astrocytoma, ependymoma, and metastatic brain tumors.

Broader topic: Hodgkin Lymphoma

Source population
Not part of this definition
Disease extent
metastatic
Treatment line
Not part of this definition
Stage
Not part of this definition
Resectability
Not part of this definition
Biomarkers, prior therapy and derivation
molecular
    prior therapy
      derivation status
      source-attested
      derivation note
      Scoped from the FDA approved indication for CARMUSTINE (product label). Only dimensions stated in that wording are part of this definition.
      source wording
      1 INDICATIONS AND USAGE Carmustine for Injection, USP is a nitrosourea indicated as palliative therapy as a single agent or in established combination therapy with other approved chemotherapeutic agents in the following: Brain tumors glioblastoma, brainstem glioma, medulloblastoma, astrocytoma, ependymoma, and metastatic brain tumors ( 1 ) Multiple myeloma-in combination with prednisone ( 1 ) Relapsed or refractory Hodgkin's lymphoma in combination with other approved drugs ( 1 ) Relapsed or refractory Non-Hodgkin's lymphomas in combination with other approved drugs ( 1 ) Carmustine for Injection, USP is indicated as palliative therapy as a single agent or in established combination therapy in the following: Brain tumors glioblastoma, brainstem glioma, medulloblastoma, astrocytoma, ependymoma, and metastatic brain tumors.

      Study evidence for this setting

      24 linked studies · Applicability is a draft source assessment, not a determination of your eligibility.

      NCT00040846 · Registry condition search · Scope: unclear

      Alemtuzumab, Fludarabine Phosphate, and Low-Dose Total Body Irradiation Before Donor Stem Cell Transplantation in Treating Patients With Hematological Malignancies

      5 outcome links · 6 safety-group records · 0 quality-of-life measures

      →

      NCT00049504 · Registry condition search · Scope: unclear

      Haploidentical Donor Bone Marrow Transplant in Treating Patients With High-Risk Hematologic Cancer

      3 outcome links · 1 safety-group records · 0 quality-of-life measures

      →

      NCT00089011 · Registry condition search · Scope: unclear

      Tacrolimus and Mycophenolate Mofetil in Preventing Graft-Versus-Host Disease in Patients Who Have Undergone Total-Body Irradiation With or Without Fludarabine Phosphate Followed by

      6 outcome links · 2 safety-group records · 0 quality-of-life measures

      →

      NCT00105001 · Registry condition search · Scope: unclear

      Tacrolimus and Mycophenolate Mofetil With or Without Sirolimus in Preventing Acute Graft-Versus-Host Disease in Patients Who Are Undergoing Donor Stem Cell Transplant for Hematolog

      5 outcome links · 3 safety-group records · 0 quality-of-life measures

      →

      NCT00112593 · Registry condition search · Scope: unclear

      Fludarabine and Total-Body Irradiation Followed By Donor Stem Cell Transplant and Cyclosporine and Mycophenolate Mofetil in Treating HIV-Positive Patients With or Without Cancer

      6 outcome links · 1 safety-group records · 0 quality-of-life measures

      →

      NCT00288067 · Registry condition search · Scope: unclear

      Fenretinide and Rituximab in Treating Patients With B-Cell Non-Hodgkin Lymphoma

      2 outcome links · 1 safety-group records · 0 quality-of-life measures

      →

      NCT00408681 · Registry condition search · Scope: unclear

      Lithium Carbonate in Treating Patients With Acute Intestinal Graft-Versus-Host-Disease (GVHD) After Donor Stem Cell Transplant

      6 outcome links · 1 safety-group records · 0 quality-of-life measures

      →

      NCT00601718 · Registry condition search · Scope: unclear

      Vorinostat, Rituximab, Ifosfamide, Carboplatin, and Etoposide in Treating Patients With Relapsed or Refractory Lymphoma or Previously Untreated T-Cell Non-Hodgkin Lymphoma or Mantl

      4 outcome links · 1 safety-group records · 0 quality-of-life measures

      →

      NCT00795769 · Registry condition search · Scope: unclear

      Ondansetron in Preventing Nausea and Vomiting in Patients Undergoing Stem Cell Transplant

      1 outcome links · 1 safety-group records · 0 quality-of-life measures

      →

      NCT00856388 · Registry condition search · Scope: unclear

      Fludarabine Phosphate, Melphalan, Total-Body Irradiation, Donor Stem Cell Transplant in Treating Patients With Hematologic Cancer or Bone Marrow Failure Disorders

      6 outcome links · 1 safety-group records · 0 quality-of-life measures

      →

      NCT00896454 · Source cited / selected · Scope: unclear

      Study of Denosumab in the Treatment of Hypercalcemia of Malignancy in Subjects With Elevated Serum Calcium

      6 outcome links · 1 safety-group records · 0 quality-of-life measures

      →

      NCT01076270 · Registry condition search · Scope: unclear

      Plerixafor and Filgrastim For Mobilization of Donor Peripheral Blood Stem Cells Before A Donor Peripheral Blood Stem Cell Transplant in Treating Patients With Hematologic Malignanc

      2 outcome links · 1 safety-group records · 0 quality-of-life measures

      →

      NCT01159067 · Registry condition search · Scope: unclear

      Deferasirox for Treating Patients Who Have Undergone Allogeneic Stem Cell Transplant and Have Iron Overload

      4 outcome links · 1 safety-group records · 0 quality-of-life measures

      →

      NCT01233921 · Registry condition search · Scope: unclear

      Palifermin in Preventing Chronic Graft-Versus-Host Disease in Patients Who Have Undergone Donor Stem Cell Transplant for Hematologic Cancer

      2 outcome links · 2 safety-group records · 0 quality-of-life measures

      →

      NCT01273766 · Registry condition search · Scope: unclear

      Deferasirox in Treating Iron Overload Caused By Blood Transfusions in Patients With Hematologic Malignancies

      3 outcome links · 3 safety-group records · 0 quality-of-life measures

      →

      NCT01771107 · Registry condition search · Scope: unclear

      Brentuximab Vedotin and Combination Chemotherapy in Treating Patients With Stage II-IV HIV-Associated Hodgkin Lymphoma

      6 outcome links · 2 safety-group records · 0 quality-of-life measures

      →

      NCT01789255 · Registry condition search · Scope: unclear

      Vorinostat, Tacrolimus, and Methotrexate in Preventing GVHD After Stem Cell Transplant in Patients With Hematological Malignancies

      6 outcome links · 1 safety-group records · 0 quality-of-life measures

      →

      NCT01805037 · Registry condition search · Scope: unclear

      Brentuximab Vedotin + Rituximab as Frontline Therapy for Pts w/ CD30+ and/or EBV+ Lymphomas

      6 outcome links · 1 safety-group records · 0 quality-of-life measures

      →

      NCT02213913 · Registry condition search · Scope: unclear

      Lenalidomide and Combination Chemotherapy (DA-EPOCH-R) in Treating Patients With MYC-Associated B-Cell Lymphomas

      6 outcome links · 4 safety-group records · 0 quality-of-life measures

      →

      NCT02595866 · Registry condition search · Scope: unclear

      Testing the Addition of an Experimental Medication MK-3475 (Pembrolizumab) to Usual Anti-Retroviral Medications in Patients With HIV and Cancer

      6 outcome links · 5 safety-group records · 0 quality-of-life measures

      →
      Source relationships and population-mapping limitations
      bindings
        mappings

          Download this complete draft source relationship record →

          Preserved source evidence · Not medical advice