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DISEASE & TREATMENT SETTING

Ontak: recurrent Cutaneous T-cell lymphoma

Source-derived catalogue. This is not a treatment recommendation or a personalised trial match.

Exact scope

Persistent or recurrent cutaneous T-cell lymphoma expressing the CD25 component of IL-2 receptor

Broader topic: Cutaneous T-Cell Lymphomas

Source population
Not part of this definition
Disease extent
recurrent
Treatment line
Not part of this definition
Stage
Not part of this definition
Resectability
Not part of this definition
Biomarkers, prior therapy and derivation
molecular
    prior therapy
      derivation status
      source-attested
      derivation note
      Scoped from the FDA approved indication for Ontak (denileukin diftitox) (accelerated-approval table). Only dimensions stated in that wording are part of this definition.
      source wording
      Persistent or recurrent cutaneous T-cell lymphoma expressing the CD25 component of IL-2 receptor

      Study evidence for this setting

      39 linked studies · Applicability is a draft source assessment, not a determination of your eligibility.

      NCT00007345 · Source cited / selected · Scope: unclear

      Depsipeptide to Treat Patients With Cutaneous T-Cell Lymphoma and Peripheral T-Cell Lymphoma

      6 outcome links · 2 safety-group records · 0 quality-of-life measures

      →

      NCT00040846 · Registry condition search · Scope: unclear

      Alemtuzumab, Fludarabine Phosphate, and Low-Dose Total Body Irradiation Before Donor Stem Cell Transplantation in Treating Patients With Hematological Malignancies

      5 outcome links · 6 safety-group records · 0 quality-of-life measures

      →

      NCT00049504 · Registry condition search · Scope: unclear

      Haploidentical Donor Bone Marrow Transplant in Treating Patients With High-Risk Hematologic Cancer

      3 outcome links · 1 safety-group records · 0 quality-of-life measures

      →

      NCT00072514 · Registry condition search · Scope: unclear

      Gemcitabine Hydrochloride, Carboplatin, Dexamethasone, and Rituximab in Treating Patients With Previously Treated Lymphoid Malignancies

      4 outcome links · 1 safety-group records · 0 quality-of-life measures

      →

      NCT00089011 · Registry condition search · Scope: unclear

      Tacrolimus and Mycophenolate Mofetil in Preventing Graft-Versus-Host Disease in Patients Who Have Undergone Total-Body Irradiation With or Without Fludarabine Phosphate Followed by

      6 outcome links · 2 safety-group records · 0 quality-of-life measures

      →

      NCT00112723 · Registry condition search · Scope: unclear

      Flavopiridol in Treating Patients With Relapsed or Refractory Lymphoma or Multiple Myeloma

      6 outcome links · 1 safety-group records · 0 quality-of-life measures

      →

      NCT00118352 · Registry condition search · Scope: unclear

      Alemtuzumab, Fludarabine Phosphate, and Total-Body Irradiation Followed by Cyclosporine and Mycophenolate Mofetil in Treating Patients Who Are Undergoing Donor Stem Cell Transplant

      6 outcome links · 3 safety-group records · 0 quality-of-life measures

      →

      NCT00131937 · Registry condition search · Scope: unclear

      Sorafenib Tosylate in Treating Patients With Recurrent Aggressive Non-Hodgkin's Lymphoma

      3 outcome links · 1 safety-group records · 0 quality-of-life measures

      →

      NCT00274651 · Registry condition search · Scope: unclear

      A Phase II Clinical Trial of PXD101 in Patients With Recurrent or Refractory Cutaneous and Peripheral T-Cell Lymphomas

      6 outcome links · 2 safety-group records · 2 quality-of-life measures

      →

      NCT00408681 · Registry condition search · Scope: unclear

      Lithium Carbonate in Treating Patients With Acute Intestinal Graft-Versus-Host-Disease (GVHD) After Donor Stem Cell Transplant

      6 outcome links · 1 safety-group records · 0 quality-of-life measures

      →

      NCT00536601 · Registry condition search · Scope: unclear

      High-Dose Chemotherapy With or Without Total-Body Irradiation Followed by Autologous Stem Cell Transplant in Treating Patients With Hematologic Cancer or Solid Tumors

      4 outcome links · 5 safety-group records · 0 quality-of-life measures

      →

      NCT00601718 · Registry condition search · Scope: unclear

      Vorinostat, Rituximab, Ifosfamide, Carboplatin, and Etoposide in Treating Patients With Relapsed or Refractory Lymphoma or Previously Untreated T-Cell Non-Hodgkin Lymphoma or Mantl

      4 outcome links · 1 safety-group records · 0 quality-of-life measures

      →

      NCT00795769 · Registry condition search · Scope: unclear

      Ondansetron in Preventing Nausea and Vomiting in Patients Undergoing Stem Cell Transplant

      1 outcome links · 1 safety-group records · 0 quality-of-life measures

      →

      NCT00856388 · Registry condition search · Scope: unclear

      Fludarabine Phosphate, Melphalan, Total-Body Irradiation, Donor Stem Cell Transplant in Treating Patients With Hematologic Cancer or Bone Marrow Failure Disorders

      6 outcome links · 1 safety-group records · 0 quality-of-life measures

      →

      NCT00918333 · Registry condition search · Scope: unclear

      Panobinostat and Everolimus in Treating Patients With Recurrent Multiple Myeloma, Non-Hodgkin Lymphoma, or Hodgkin Lymphoma

      6 outcome links · 2 safety-group records · 0 quality-of-life measures

      →

      NCT01044745 · Registry condition search · Scope: unclear

      Rituximab in Preventing Acute Graft-Versus-Host Disease in a Donor Stem Cell Transplant for Hematologic Cancer

      4 outcome links · 1 safety-group records · 0 quality-of-life measures

      →

      NCT01076270 · Registry condition search · Scope: unclear

      Plerixafor and Filgrastim For Mobilization of Donor Peripheral Blood Stem Cells Before A Donor Peripheral Blood Stem Cell Transplant in Treating Patients With Hematologic Malignanc

      2 outcome links · 1 safety-group records · 0 quality-of-life measures

      →

      NCT01093586 · Registry condition search · Scope: unclear

      Donor Umbilical Cord Blood Stem Cell Transplant in Treating Patients With Hematologic Malignancies

      6 outcome links · 1 safety-group records · 0 quality-of-life measures

      →

      NCT01110135 · Registry condition search · Scope: unclear

      Bendamustine Hydrochloride, Etoposide, Dexamethasone, and Filgrastim For Peripheral Blood Stem Cell Mobilization in Treating Patients With Refractory or Recurrent Lymphoma or Multi

      1 outcome links · 1 safety-group records · 0 quality-of-life measures

      →

      NCT01159067 · Registry condition search · Scope: unclear

      Deferasirox for Treating Patients Who Have Undergone Allogeneic Stem Cell Transplant and Have Iron Overload

      4 outcome links · 1 safety-group records · 0 quality-of-life measures

      →
      Source relationships and population-mapping limitations
      bindings
        mappings

          Download this complete draft source relationship record →

          Preserved source evidence · Not medical advice