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DISEASE & TREATMENT SETTING

LYMPHIR: refractory Cutaneous T-cell lymphoma after prior therapy

Source-derived catalogue. This is not a treatment recommendation or a personalised trial match.

Exact scope

1 INDICATIONS AND USAGE LYMPHIR is indicated for the treatment of adult patients with relapsed or refractory Stage I-III cutaneous T-cell lymphoma (CTCL) after at least one prior systemic therapy.

Broader topic: Cutaneous T-Cell Lymphomas

Source population
Not part of this definition
Disease extent
refractory
Treatment line
Not part of this definition
Stage
Not part of this definition
Resectability
Not part of this definition
Biomarkers, prior therapy and derivation
molecular
    prior therapy
    1. class
      after at least one prior systemic therapy
      status
      required
    derivation status
    source-attested
    derivation note
    Scoped from the FDA approved indication for LYMPHIR (product label). Only dimensions stated in that wording are part of this definition.
    source wording
    1 INDICATIONS AND USAGE LYMPHIR is indicated for the treatment of adult patients with relapsed or refractory Stage I-III cutaneous T-cell lymphoma (CTCL) after at least one prior systemic therapy.

    Study evidence for this setting

    36 linked studies · Applicability is a draft source assessment, not a determination of your eligibility.

    NCT00040846 · Registry condition search · Scope: unclear

    Alemtuzumab, Fludarabine Phosphate, and Low-Dose Total Body Irradiation Before Donor Stem Cell Transplantation in Treating Patients With Hematological Malignancies

    5 outcome links · 6 safety-group records · 0 quality-of-life measures

    →

    NCT00049504 · Registry condition search · Scope: unclear

    Haploidentical Donor Bone Marrow Transplant in Treating Patients With High-Risk Hematologic Cancer

    3 outcome links · 1 safety-group records · 0 quality-of-life measures

    →

    NCT00089011 · Registry condition search · Scope: unclear

    Tacrolimus and Mycophenolate Mofetil in Preventing Graft-Versus-Host Disease in Patients Who Have Undergone Total-Body Irradiation With or Without Fludarabine Phosphate Followed by

    6 outcome links · 2 safety-group records · 0 quality-of-life measures

    →

    NCT00112723 · Registry condition search · Scope: unclear

    Flavopiridol in Treating Patients With Relapsed or Refractory Lymphoma or Multiple Myeloma

    6 outcome links · 1 safety-group records · 0 quality-of-life measures

    →

    NCT00118352 · Registry condition search · Scope: unclear

    Alemtuzumab, Fludarabine Phosphate, and Total-Body Irradiation Followed by Cyclosporine and Mycophenolate Mofetil in Treating Patients Who Are Undergoing Donor Stem Cell Transplant

    6 outcome links · 3 safety-group records · 0 quality-of-life measures

    →

    NCT00274651 · Registry condition search · Scope: unclear

    A Phase II Clinical Trial of PXD101 in Patients With Recurrent or Refractory Cutaneous and Peripheral T-Cell Lymphomas

    6 outcome links · 2 safety-group records · 2 quality-of-life measures

    →

    NCT00408681 · Registry condition search · Scope: unclear

    Lithium Carbonate in Treating Patients With Acute Intestinal Graft-Versus-Host-Disease (GVHD) After Donor Stem Cell Transplant

    6 outcome links · 1 safety-group records · 0 quality-of-life measures

    →

    NCT00425555 · Source cited / selected · Scope: unclear

    Study of Oral LBH589 in Adult Patients With Refractory Cutaneous T-Cell Lymphoma

    6 outcome links · 2 safety-group records · 3 quality-of-life measures

    →

    NCT00536601 · Registry condition search · Scope: unclear

    High-Dose Chemotherapy With or Without Total-Body Irradiation Followed by Autologous Stem Cell Transplant in Treating Patients With Hematologic Cancer or Solid Tumors

    4 outcome links · 5 safety-group records · 0 quality-of-life measures

    →

    NCT00601718 · Registry condition search · Scope: unclear

    Vorinostat, Rituximab, Ifosfamide, Carboplatin, and Etoposide in Treating Patients With Relapsed or Refractory Lymphoma or Previously Untreated T-Cell Non-Hodgkin Lymphoma or Mantl

    4 outcome links · 1 safety-group records · 0 quality-of-life measures

    →

    NCT00795769 · Registry condition search · Scope: unclear

    Ondansetron in Preventing Nausea and Vomiting in Patients Undergoing Stem Cell Transplant

    1 outcome links · 1 safety-group records · 0 quality-of-life measures

    →

    NCT00856388 · Registry condition search · Scope: unclear

    Fludarabine Phosphate, Melphalan, Total-Body Irradiation, Donor Stem Cell Transplant in Treating Patients With Hematologic Cancer or Bone Marrow Failure Disorders

    6 outcome links · 1 safety-group records · 0 quality-of-life measures

    →

    NCT00918333 · Registry condition search · Scope: unclear

    Panobinostat and Everolimus in Treating Patients With Recurrent Multiple Myeloma, Non-Hodgkin Lymphoma, or Hodgkin Lymphoma

    6 outcome links · 2 safety-group records · 0 quality-of-life measures

    →

    NCT01044745 · Registry condition search · Scope: unclear

    Rituximab in Preventing Acute Graft-Versus-Host Disease in a Donor Stem Cell Transplant for Hematologic Cancer

    4 outcome links · 1 safety-group records · 0 quality-of-life measures

    →

    NCT01076270 · Registry condition search · Scope: unclear

    Plerixafor and Filgrastim For Mobilization of Donor Peripheral Blood Stem Cells Before A Donor Peripheral Blood Stem Cell Transplant in Treating Patients With Hematologic Malignanc

    2 outcome links · 1 safety-group records · 0 quality-of-life measures

    →

    NCT01093586 · Registry condition search · Scope: unclear

    Donor Umbilical Cord Blood Stem Cell Transplant in Treating Patients With Hematologic Malignancies

    6 outcome links · 1 safety-group records · 0 quality-of-life measures

    →

    NCT01110135 · Registry condition search · Scope: unclear

    Bendamustine Hydrochloride, Etoposide, Dexamethasone, and Filgrastim For Peripheral Blood Stem Cell Mobilization in Treating Patients With Refractory or Recurrent Lymphoma or Multi

    1 outcome links · 1 safety-group records · 0 quality-of-life measures

    →

    NCT01159067 · Registry condition search · Scope: unclear

    Deferasirox for Treating Patients Who Have Undergone Allogeneic Stem Cell Transplant and Have Iron Overload

    4 outcome links · 1 safety-group records · 0 quality-of-life measures

    →

    NCT01233921 · Registry condition search · Scope: unclear

    Palifermin in Preventing Chronic Graft-Versus-Host Disease in Patients Who Have Undergone Donor Stem Cell Transplant for Hematologic Cancer

    2 outcome links · 2 safety-group records · 0 quality-of-life measures

    →

    NCT01258998 · Registry condition search · Scope: unclear

    Study of Akt Inhibitor MK2206 in Patients With Relapsed Lymphoma

    6 outcome links · 1 safety-group records · 0 quality-of-life measures

    →
    Source relationships and population-mapping limitations
    bindings
      mappings

        Download this complete draft source relationship record →

        Preserved source evidence · Not medical advice