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DISEASE & TREATMENT SETTING

DOCIVYX: metastatic Breast cancer after prior therapy

Source-derived catalogue. This is not a treatment recommendation or a personalised trial match.

Exact scope

1.1 Breast Cancer DOCIVYX is indicated for the treatment of patients with locally advanced or metastatic breast cancer after failure of prior chemotherapy.

Broader topic: Breast Cancer

Source population
Not part of this definition
Disease extent
metastatic
Treatment line
Not part of this definition
Stage
Not part of this definition
Resectability
Not part of this definition
Biomarkers, prior therapy and derivation
molecular
    prior therapy
    1. class
      after failure of prior chemotherapy
      status
      required
    derivation status
    source-attested
    derivation note
    Scoped from the FDA approved indication for DOCIVYX (product label). Only dimensions stated in that wording are part of this definition.
    source wording
    1.1 Breast Cancer DOCIVYX is indicated for the treatment of patients with locally advanced or metastatic breast cancer after failure of prior chemotherapy.

    Study evidence for this setting

    67 linked studies · Applicability is a draft source assessment, not a determination of your eligibility.

    NCT00075764 · Source cited / selected · Scope: unclear

    S0226 Anastrozole With or Without Fulvestrant as First-Line Therapy in Postmenopausal Women With Metastatic Breast Cancer

    4 outcome links · 2 safety-group records · 0 quality-of-life measures

    →

    NCT00408681 · Registry condition search · Scope: unclear

    Lithium Carbonate in Treating Patients With Acute Intestinal Graft-Versus-Host-Disease (GVHD) After Donor Stem Cell Transplant

    6 outcome links · 1 safety-group records · 0 quality-of-life measures

    →

    NCT00556374 · Source cited / selected · Scope: unclear

    Study to Determine Treatment Effects of Denosumab in Patients With Breast Cancer Receiving Aromatase Inhibitor Therapy

    6 outcome links · 4 safety-group records · 0 quality-of-life measures

    →

    NCT00567190 · Source cited / selected · Scope: unclear

    A Study to Evaluate Pertuzumab + Trastuzumab + Docetaxel vs. Placebo + Trastuzumab + Docetaxel in Previously Untreated HER2-Positive Metastatic Breast Cancer

    6 outcome links · 3 safety-group records · 1 quality-of-life measures

    →

    NCT00602043 · Source cited / selected · Scope: unclear

    F-18 16 Alpha-Fluoroestradiol-Labeled Positron Emission Tomography in Predicting Response to First-Line Hormone Therapy in Patients With Stage IV Breast Cancer

    4 outcome links · 1 safety-group records · 1 quality-of-life measures

    →

    NCT00795769 · Registry condition search · Scope: unclear

    Ondansetron in Preventing Nausea and Vomiting in Patients Undergoing Stem Cell Transplant

    1 outcome links · 1 safety-group records · 0 quality-of-life measures

    →

    NCT00829166 · Source cited / selected · Scope: unclear

    A Study of Trastuzumab Emtansine Versus Capecitabine + Lapatinib in Participants With HER2-positive Locally Advanced or Metastatic Breast Cancer

    6 outcome links · 3 safety-group records · 2 quality-of-life measures

    →

    NCT00863655 · Source cited / selected · Scope: unclear

    Everolimus in Combination With Exemestane in the Treatment of Postmenopausal Women With Estrogen Receptor Positive Locally Advanced or Metastatic Breast Cancer Who Are Refractory t

    6 outcome links · 2 safety-group records · 1 quality-of-life measures

    →

    NCT00869206 · Source cited / selected · Scope: unclear

    Zoledronic Acid in Treating Patients With Metastatic Breast Cancer, Metastatic Prostate Cancer, or Multiple Myeloma With Bone Involvement

    6 outcome links · 2 safety-group records · 1 quality-of-life measures

    →

    NCT00896454 · Source cited / selected · Scope: unclear

    Study of Denosumab in the Treatment of Hypercalcemia of Malignancy in Subjects With Elevated Serum Calcium

    6 outcome links · 1 safety-group records · 0 quality-of-life measures

    →

    NCT01007942 · Source cited / selected · Scope: unclear

    Daily Everolimus in Combination With Trastuzumab and Vinorelbine in HER2/Neu Positive Women With Locally Advanced or Metastatic Breast Cancer

    6 outcome links · 2 safety-group records · 1 quality-of-life measures

    →

    NCT01037790 · Registry condition search · Scope: unclear

    Phase II Trial of the Cyclin-Dependent Kinase Inhibitor PD 0332991 in Patients With Cancer

    1 outcome links · 5 safety-group records · 0 quality-of-life measures

    →

    NCT01120184 · Source cited / selected · Scope: unclear

    A Study of Trastuzumab Emtansine (T-DM1) Plus Pertuzumab/Pertuzumab Placebo Versus Trastuzumab [Herceptin] Plus a Taxane in Participants With Metastatic Breast Cancer (MARIANNE)

    6 outcome links · 3 safety-group records · 8 quality-of-life measures

    →

    NCT01159067 · Registry condition search · Scope: unclear

    Deferasirox for Treating Patients Who Have Undergone Allogeneic Stem Cell Transplant and Have Iron Overload

    4 outcome links · 1 safety-group records · 0 quality-of-life measures

    →

    NCT01242800 · Source cited / selected · Scope: unclear

    Early Surgery or Standard Palliative Therapy in Treating Patients With Stage IV Breast Cancer

    3 outcome links · 2 safety-group records · 1 quality-of-life measures

    →

    NCT01390818 · Registry condition search · Scope: unclear

    Trial of MEK Inhibitor and PI3K/mTOR Inhibitor in Subjects With Locally Advanced or Metastatic Solid Tumors

    6 outcome links · 15 safety-group records · 0 quality-of-life measures

    →

    NCT01419197 · Source cited / selected · Scope: unclear

    A Study of Trastuzumab Emtansine in Comparison With Treatment of Physician's Choice in Participants With HER2-positive Breast Cancer Who Have Received at Least Two Prior Regimens o

    6 outcome links · 3 safety-group records · 2 quality-of-life measures

    →

    NCT01602380 · Source cited / selected · Scope: unclear

    A Global Study to Compare the Effects of Fulvestrant and Arimidex in a Subset of Patients With Breast Cancer.

    6 outcome links · 2 safety-group records · 1 quality-of-life measures

    →

    NCT01631552 · Source cited / selected · Scope: unclear

    Study of Sacituzumab Govitecan-hziy (IMMU-132) in Adults With Epithelial Cancer

    6 outcome links · 1 safety-group records · 0 quality-of-life measures

    →

    NCT01761240 · Registry condition search · Scope: unclear

    Dose Escalation Study MORAb-066 Targeting Tissue Factor (TF)-Expressing Malignancies Including Breast, Pancreatic, Colorectal, NSCLC

    6 outcome links · 5 safety-group records · 0 quality-of-life measures

    →
    Source relationships and population-mapping limitations
    bindings
      mappings

        Download this complete draft source relationship record →

        Preserved source evidence · Not medical advice