TriangleNCT05959564 · STUDY IN CONTEXT
A Chatbot Intervention for Reducing HPV Vaccine Hesitancy
Draft scope assessment: narrower. Linked by condition-string match at the cancer-entity level. The study's eligibility - stage, biomarker, treatment line and prior therapy - has not been reconciled against this page's definition, so its population is narrower than this page in ways not yet recorded. Found by searching ClinicalTrials.gov for this cancer type, restricted to studies that have posted results to the registry. No FDA notice, FDA label or NCI summary held by this site cites this study. Because the search asked for posted results, studies without posted results were never looked for, so their absence from this page means nothing.
Read the full study record and all posted results →
Linked outcomes
Participants' attitudes toward HPV vaccination were measured by seven questions such as "The HPV vaccine is beneficial for adolescents." The responses were recorded on 1 (strongly disagree) to 5 (strongly agree) scales. Final score was the average of all 7 questions.
Participants' intentions toward vaccinating their children against HPV were measured by three questions such as "I am likely to get my child/children the HPV vaccine." Responses were indicated on 1 (strongly disagree) to 5 (strongly agree) scales. The final score was the average of the three questions.
Ratings of the Chatbot were measured by nine questions such as "How would you describe the HPV chatbot you just interacted with? - Engaging" on 1 (strongly disagree) to 5 (strongly agree) scales. The final score was the average of the nine questions.
Reported safety
Quality of life and patient-reported measures
No linked quality-of-life measure is recorded for this setting and study.
Full draft applicability and source-link record
- trial
- release id
- clinical-indications-draft-1
- disease state id
- ds-anal-cancer
- nct id
- NCT05959564
- trial label
- A Chatbot Intervention for Reducing HPV Vaccine Hesitancy
- applicability
- narrower
- applicability note
- Linked by condition-string match at the cancer-entity level. The study's eligibility - stage, biomarker, treatment line and prior therapy - has not been reconciled against this page's definition, so its population is narrower than this page in ways not yet recorded.
- curation status
- draft
- reviewed by
- Source null
- reviewed at
- Source null
- created at
- 2026-09-10T00:00:00Z
- provenance class
- registry-condition-search
- discovery note
- Found by searching ClinicalTrials.gov for this cancer type, restricted to studies that have posted results to the registry. No FDA notice, FDA label or NCI summary held by this site cites this study. Because the search asked for posted results, studies without posted results were never looked for, so their absence from this page means nothing.
- outcome Count
- 3
- harms Count
- 3
- qol Count
- 0
- outcomes
- release id
- clinical-indications-draft-1
- disease state id
- ds-anal-cancer
- nct id
- NCT05959564
- outcome key
- om-0000
- source section id
- NCT05959564-om-0000
- source outcome index
- 0
- endpoint
- Attitudes Toward HPV Vaccination
- endpoint definition
- Participants' attitudes toward HPV vaccination were measured by seven questions such as "The HPV vaccine is beneficial for adolescents." The responses were recorded on 1 (strongly disagree) to 5 (strongly agree) scales. Final score was the average of all 7 questions.
- time origin
- baseline posttest (test took approximately 5 minutes to complete)
- analysis role
- primary
- reporting status
- POSTED
- data cutoff
- Source null
- population note
- Source null
- curation status
- draft
- reviewed by
- Source null
- reviewed at
- Source null
- created at
- 2026-09-10T00:00:00Z
- release id
- clinical-indications-draft-1
- disease state id
- ds-anal-cancer
- nct id
- NCT05959564
- outcome key
- om-0001
- source section id
- NCT05959564-om-0001
- source outcome index
- 1
- endpoint
- Intentions Toward HPV Vaccination
- endpoint definition
- Participants' intentions toward vaccinating their children against HPV were measured by three questions such as "I am likely to get my child/children the HPV vaccine." Responses were indicated on 1 (strongly disagree) to 5 (strongly agree) scales. The final score was the average of the three questions.
- time origin
- baseline posttest (test took approximately 5 minutes to complete)
- analysis role
- primary
- reporting status
- POSTED
- data cutoff
- Source null
- population note
- Source null
- curation status
- draft
- reviewed by
- Source null
- reviewed at
- Source null
- created at
- 2026-09-10T00:00:00Z
- release id
- clinical-indications-draft-1
- disease state id
- ds-anal-cancer
- nct id
- NCT05959564
- outcome key
- om-0002
- source section id
- NCT05959564-om-0002
- source outcome index
- 2
- endpoint
- Ratings of the Chatbot
- endpoint definition
- Ratings of the Chatbot were measured by nine questions such as "How would you describe the HPV chatbot you just interacted with? - Engaging" on 1 (strongly disagree) to 5 (strongly agree) scales. The final score was the average of the nine questions.
- time origin
- baseline posttest (test took approximately 5 minutes to complete)
- analysis role
- secondary
- reporting status
- POSTED
- data cutoff
- Source null
- population note
- participants in the no chatbot control condition were not asked to rate the chatbot.
- curation status
- draft
- reviewed by
- Source null
- reviewed at
- Source null
- created at
- 2026-09-10T00:00:00Z
- arms
- release id
- clinical-indications-draft-1
- disease state id
- ds-anal-cancer
- nct id
- NCT05959564
- outcome key
- om-0000
- arm key
- OG000
- arm label
- Personalized Chatbot Condition
- regimen
- After reading a standard CDC HPV vaccine message, participants interacted with a chatbot designed to deliver personalized HPV vaccine messages (i.e., tailored to their personalities). Personalized Chatbot Intervention: In this intervention, participants first saw a standard CDC HPV vaccine message. After that they were invited to interact with a chatbot designed to deliver additional HPV vaccine messages, which were tailored to their personalities.
- analyzed count
- 152
- analyzed unit
- Participants
- is comparator
- Source null
- source pointer
- NCT05959564-om-0000#groups/OG000
- release id
- clinical-indications-draft-1
- disease state id
- ds-anal-cancer
- nct id
- NCT05959564
- outcome key
- om-0000
- arm key
- OG001
- arm label
- Non-Personalized Chatbot Condition
- regimen
- After reading a standard CDC HPV vaccine message, participants interacted with a chatbot designed to deliver HPV vaccine messages, which were not tailored to their personalities. Non-Personalized Chatbot Intervention: In this intervention, participants first saw a standard CDC HPV vaccine message. After that they were invited to interact with a chatbot designed to deliver additional HPV vaccine messages, which were not tailored to their personalities.
- analyzed count
- 154
- analyzed unit
- Participants
- is comparator
- Source null
- source pointer
- NCT05959564-om-0000#groups/OG001
- release id
- clinical-indications-draft-1
- disease state id
- ds-anal-cancer
- nct id
- NCT05959564
- outcome key
- om-0000
- arm key
- OG002
- arm label
- No Chatbot Control Condition
- regimen
- Participants read a standard CDC HPV vaccine message without interacting with any chatbot that delivers additional messages. No Chatbot Control: In this intervention, participants saw a standard CDC HPV vaccine message only and did not interact with any chatbot.
- analyzed count
- 150
- analyzed unit
- Participants
- is comparator
- Source null
- source pointer
- NCT05959564-om-0000#groups/OG002
- release id
- clinical-indications-draft-1
- disease state id
- ds-anal-cancer
- nct id
- NCT05959564
- outcome key
- om-0001
- arm key
- OG000
- arm label
- Personalized Chatbot Condition
- regimen
- After reading a standard CDC HPV vaccine message, participants interacted with a chatbot designed to deliver personalized HPV vaccine messages (i.e., tailored to their personalities). Personalized Chatbot Intervention: In this intervention, participants first saw a standard CDC HPV vaccine message. After that they were invited to interact with a chatbot designed to deliver additional HPV vaccine messages, which were tailored to their personalities.
- analyzed count
- 152
- analyzed unit
- Participants
- is comparator
- Source null
- source pointer
- NCT05959564-om-0001#groups/OG000
- release id
- clinical-indications-draft-1
- disease state id
- ds-anal-cancer
- nct id
- NCT05959564
- outcome key
- om-0001
- arm key
- OG001
- arm label
- Non-Personalized Chatbot Condition
- regimen
- After reading a standard CDC HPV vaccine message, participants interacted with a chatbot designed to deliver HPV vaccine messages, which were not tailored to their personalities. Non-Personalized Chatbot Intervention: In this intervention, participants first saw a standard CDC HPV vaccine message. After that they were invited to interact with a chatbot designed to deliver additional HPV vaccine messages, which were not tailored to their personalities.
- analyzed count
- 154
- analyzed unit
- Participants
- is comparator
- Source null
- source pointer
- NCT05959564-om-0001#groups/OG001
- release id
- clinical-indications-draft-1
- disease state id
- ds-anal-cancer
- nct id
- NCT05959564
- outcome key
- om-0001
- arm key
- OG002
- arm label
- No Chatbot Control Condition
- regimen
- Participants read a standard CDC HPV vaccine message without interacting with any chatbot that delivers additional messages. No Chatbot Control: In this intervention, participants saw a standard CDC HPV vaccine message only and did not interact with any chatbot.
- analyzed count
- 150
- analyzed unit
- Participants
- is comparator
- Source null
- source pointer
- NCT05959564-om-0001#groups/OG002
- release id
- clinical-indications-draft-1
- disease state id
- ds-anal-cancer
- nct id
- NCT05959564
- outcome key
- om-0002
- arm key
- OG000
- arm label
- Personalized Chatbot Condition
- regimen
- After reading a standard CDC HPV vaccine message, participants interacted with a chatbot designed to deliver personalized HPV vaccine messages (i.e., tailored to their personalities). Personalized Chatbot Intervention: In this intervention, participants first saw a standard CDC HPV vaccine message. After that they were invited to interact with a chatbot designed to deliver additional HPV vaccine messages, which were tailored to their personalities.
- analyzed count
- 130
- analyzed unit
- Participants
- is comparator
- Source null
- source pointer
- NCT05959564-om-0002#groups/OG000
- release id
- clinical-indications-draft-1
- disease state id
- ds-anal-cancer
- nct id
- NCT05959564
- outcome key
- om-0002
- arm key
- OG001
- arm label
- Non-Personalized Chatbot Condition
- regimen
- After reading a standard CDC HPV vaccine message, participants interacted with a chatbot designed to deliver HPV vaccine messages, which were not tailored to their personalities. Non-Personalized Chatbot Intervention: In this intervention, participants first saw a standard CDC HPV vaccine message. After that they were invited to interact with a chatbot designed to deliver additional HPV vaccine messages, which were not tailored to their personalities.
- analyzed count
- 130
- analyzed unit
- Participants
- is comparator
- Source null
- source pointer
- NCT05959564-om-0002#groups/OG001
- release id
- clinical-indications-draft-1
- disease state id
- ds-anal-cancer
- nct id
- NCT05959564
- outcome key
- om-0002
- arm key
- OG002
- arm label
- No Chatbot Control Condition
- regimen
- Participants read a standard CDC HPV vaccine message without interacting with any chatbot that delivers additional messages. No Chatbot Control: In this intervention, participants saw a standard CDC HPV vaccine message only and did not interact with any chatbot.
- analyzed count
- 0
- analyzed unit
- Participants
- is comparator
- Source null
- source pointer
- NCT05959564-om-0002#groups/OG002
- harms
- release id
- clinical-indications-draft-1
- disease state id
- ds-anal-cancer
- nct id
- NCT05959564
- harm key
- EG000
- source section id
- NCT05959564-ae
- event group key
- EG000
- event group label
- Personalized Chatbot Condition
- serious affected
- 0
- serious at risk
- 0
- other affected
- 0
- other at risk
- 0
- frequency threshold
- 0
- collection period
- Source null
- event definition
- Deaths and/or adverse events were not monitored/assessed as this was an online study where participants completed the survey on their own computer at a location of their choice.
- undenominated note
- Source null
- curation status
- draft
- reviewed by
- Source null
- reviewed at
- Source null
- created at
- 2026-09-10T00:00:00Z
- release id
- clinical-indications-draft-1
- disease state id
- ds-anal-cancer
- nct id
- NCT05959564
- harm key
- EG001
- source section id
- NCT05959564-ae
- event group key
- EG001
- event group label
- Non-Personalized Chatbot Condition
- serious affected
- 0
- serious at risk
- 0
- other affected
- 0
- other at risk
- 0
- frequency threshold
- 0
- collection period
- Source null
- event definition
- Deaths and/or adverse events were not monitored/assessed as this was an online study where participants completed the survey on their own computer at a location of their choice.
- undenominated note
- Source null
- curation status
- draft
- reviewed by
- Source null
- reviewed at
- Source null
- created at
- 2026-09-10T00:00:00Z
- release id
- clinical-indications-draft-1
- disease state id
- ds-anal-cancer
- nct id
- NCT05959564
- harm key
- EG002
- source section id
- NCT05959564-ae
- event group key
- EG002
- event group label
- No Chatbot Control Condition
- serious affected
- 0
- serious at risk
- 0
- other affected
- 0
- other at risk
- 0
- frequency threshold
- 0
- collection period
- Source null
- event definition
- Deaths and/or adverse events were not monitored/assessed as this was an online study where participants completed the survey on their own computer at a location of their choice.
- undenominated note
- Source null
- curation status
- draft
- reviewed by
- Source null
- reviewed at
- Source null
- created at
- 2026-09-10T00:00:00Z
- quality of life
- setting source links
Preserved source evidence · Not medical advice